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Material Safety Data Sheet: O-Ethyl-O-2,4,5-Trichlorophenyl-Ethylthiophosphonate

Identification

Product Name: O-Ethyl-O-2,4,5-Trichlorophenyl-Ethylthiophosphonate
Synonyms: ETP, Trichlorophenyl Thiophosphonate
Chemical Formula: C10H12Cl3O2PS
CAS Number: 78-00-2
Recommended Use: Industrial chemical synthesis, research laboratories
Supplier: Indicate local supplier contact information on label
Emergency Contact: Poison Control Center, local emergency number

Hazard Identification

Classification: Acute Toxicity (Oral), Acute Toxicity (Dermal), Skin Irritation, Eye Damage, Specific Target Organ Toxicity
Signal Word: Danger
Hazard Statements: Toxic if swallowed, causes skin and eye irritation, suspected of causing harm to organs through repeated exposure, harmful to aquatic life with long-lasting effects
Pictograms: Skull and crossbones, exclamation mark, environment
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Precautionary Statements: Wash hands thoroughly after handling, do not eat, drink or smoke when using, avoid release to environment

Composition / Information on Ingredients

Chemical Identity: O-Ethyl-O-2,4,5-Trichlorophenyl-Ethylthiophosphonate
Purity/Concentration: >98%
Impurities/Hazardous Components: None reported above 0.1%
Other Identifiers: None known
Molecular Weight: 349.6 g/mol
EC Number: 201-114-5

First Aid Measures

Inhalation: Move to fresh air immediately, keep airways clear, provide artificial respiration if needed, seek medical help
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes, call poison control
Eye Contact: Rinse with water for at least 15 minutes, hold eyelids apart, remove contact lenses, seek urgent medical attention
Ingestion: Give water to conscious person, do not induce vomiting, seek immediate emergency medical advice
Note to Physician: Monitor respiration, treat symptomatically, keep under medical observation due to risk of delayed effects

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, do not use water jet
Hazards from Combustion: Phosphorus oxides, sulfur oxides, hydrochloric acid fumes, toxic and irritating gases
Protective Equipment: Self-contained breathing apparatus, full protective suit, maintain safe distance
Special Procedures: Cool containers exposed to flame with water spray, prevent runoff into water sources

Accidental Release Measures

Personal Protection: Use chemical-resistant gloves, safety goggles, respirators rated for organic vapors, and protective clothing
Environmental Precautions: Prevent entry into drains, waterways, or soil, report releases to regulatory authorities
Cleanup Methods: Absorb spill with inert material, place in chemical waste container, wash spill site after removal, ventilate area, avoid dust formation

Handling and Storage

Handling Practices: Use only in well-ventilated areas, avoid contact with skin, eyes, and clothing, prevent inhalation of vapor or mist, keep away from foodstuffs
Storage Conditions: Store in tightly closed original containers, away from incompatible materials such as strong oxidants and acids, out of direct sunlight, keep containers dry and cool
Incompatible Products: Strong oxidizing agents, acids, moisture

Exposure Controls and Personal Protection

Engineering Controls: Use fume hoods for laboratory operations, local exhaust ventilation for working areas
Occupational Exposure Limits: No official limits, follow strict hygiene and PPE practices
Personal Protection: Chemical-resistant gloves (nitrile, butyl rubber), safety goggles, body protection, respirators suitable for organic vapors, do not wear contact lenses, wash hands after handling, remove contaminated clothing before entering eating areas

Physical and Chemical Properties

Appearance: Pale yellow to colorless liquid
Odor: Characteristic, sharp, unpleasant
pH: Not applicable
Boiling Point: 185–195°C (under reduced pressure)
Melting Point: Not determined
Flash Point: >85°C
Solubility (Water): Negligible
Solubility (Solvents): Soluble in chloroform, acetone
Vapor Density: Not available
Density: Approximately 1.5 g/cm3
Partition Coefficient: Not determined
Decomposition Temperature: Decomposes on strong heating
Viscosity: Not available

Stability and Reactivity

Chemical Stability: Stable under standard storage conditions
Reactivity: Sensitive to light and heat, reacts with strong oxidizers
Hazardous Polymerization: Will not occur under normal conditions
Conditions to Avoid: Excessive heat, direct sunlight, moist environments
Hazardous Decomposition Products: Hydrogen chloride, phosphorus oxides, sulfur oxides

Toxicological Information

Likely Routes of Exposure: Inhalation, dermal, oral
Acute Toxicity: Highly toxic, fatal in small doses
LD50 (oral, rat): Approx. 3 mg/kg
LC50 (inhalation, rat): Data not available
Skin Corrosion/Irritation: Severe irritant, risk of local effects
Eye Damage/Irritation: Serious damage possible
Chronic Effects: Repeated or prolonged exposure affects nervous system, liver, kidneys, possibly endocrine organs
Carcinogenicity: Not identified as carcinogen by recognized authorities
Other Health Effects: May cause respiratory depression, convulsions, delayed neurotoxicity, cholinesterase inhibition

Ecological Information

Toxicity to Aquatic Life: Harmful, risk of bioaccumulation in organisms
Degradability: Slow breakdown in environment, persistent in soil and water
Mobility: Low water solubility, binds to sediments
Bioaccumulative Potential: Possible, due to high lipophilicity
Other Effects: High risk to non-target species including beneficial insects, amphibians, aquatic invertebrates

Disposal Considerations

Waste Treatment Methods: Incinerate in licensed facility using approved method, do not discharge to sewer systems
Contaminated Packaging: Treat packages as hazardous, triple rinse, puncture before final disposal
Disposal Restrictions: No landfilling of pure substance or large contaminated materials, follow all national and international regulations for hazardous chemical waste

Transport Information

UN Number: 3018
UN Proper Shipping Name: Organophosphorus Pesticide, Liquid, Toxic, Flammable
Transport Hazard Class: 6.1 (Toxic Substances)
Packing Group: I (High Danger)
Environmental Hazards: Marine pollutant
Special Transport Precautions: Keep containers tightly closed, segregate from incompatible substances, label clearly, emergency procedures for spills required during transport

Regulatory Information

OSHA Status: Regulated hazardous material
TSCA Status: Listed
SARA Title III: Subject to reporting under Section 313 (Toxic Release Inventory)
European Regulations: Classified as toxic and dangerous for environment under Directive 67/548/EEC
Canada WHMIS: Controlled product, D1A (dangerously toxic material), D2B (irritant)
Other Regulations: Specific national and local requirements may apply, consult relevant authorities for up-to-date compliance