© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Neomycin Sulfate
Synonyms: Neomycin Sulfate Salt, Neomycin B Sulfate
Chemical Formula: C23H46N6O13·2H2SO4
CAS Number: 1405-10-3
Use: Antibiotic in pharmaceutical, veterinary, and laboratory settings
Supplier: Contact details for manufacturer or distributor
Emergency Contact: Phone number for 24-hour emergency assistance
Classification: Eye irritant, skin irritant, respiratory sensitizer
Hazard Statements: Causes allergic skin reactions, risk of severe eye irritation, may cause respiratory irritation, may trigger asthmatic symptoms in sensitive individuals
Pictograms: Exclamation mark, health hazard
Signal Word: Warning
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, store in a tightly closed container, use personal protective equipment if direct exposure risk exists
Chemical: Neomycin Sulfate
Concentration: 100% pure or as labeled in commercial products
Impurities: Trace levels of related aminoglycoside compounds possible, not typically present in significant amounts
Molecular Weight: Approximately 614.64 g/mol for neomycin base, varies with sulfate addition
Other Ingredients: None for pure bulk product; formulation may include stabilizers or fillers in drug preparations
Inhalation: Move person to fresh air, seek medical attention if symptoms develop such as coughing or difficulty breathing, provide respiratory support if signs of distress appear
Skin Contact: Remove contaminated clothing, wash skin with soap and water for at least 15 minutes, consult a physician if irritation or sensitization occurs
Eye Contact: Rinse cautiously with water for several minutes, hold eyelids open to ensure thorough irrigation, remove contact lenses if present, seek medical care for persistent irritation
Ingestion: Rinse mouth with water, do not induce vomiting, get emergency medical help if large quantities ingested or if symptoms like nausea or abdominal pain persist
Most Important Symptoms: Allergic reactions, redness, blistering, breathing difficulties, eye pain or vision changes
Suitable Extinguishing Media: Water spray, dry chemical powder, carbon dioxide, alcohol-resistant foam
Unsuitable Media: Do not use high-pressure water streams that may spread dust
Specific Hazards: Product does not ignite easily, but decomposition at high temperatures can release toxic fumes including nitrogen oxides, sulfur oxides
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective clothing to prevent exposure to smoke and decomposition products
Special Procedures: Prevent fire-fighting runoff from entering drains or watercourses, cool containers with water if exposed to heat
Personal Precautions: Wear protective equipment including gloves, eye protection, and a dust mask or particulate respirator
Environmental Precautions: Prevent further leakage or spillage, do not allow to enter soil, sewers, or waterways where aquatic organisms may be impacted
Methods for Clean-Up: Scoop up spilled material mechanically, avoid creating airborne dust, place in suitable, labeled containers for disposal, clean spill area thoroughly with water, ventilate area if necessary
Handling: Handle in a well-ventilated area, minimize dust generation and accumulation, avoid contact with skin, eyes, and clothing, use only with adequate protection
Storage: Store in a cool, dry, well-ventilated place away from incompatible substances such as strong oxidizers, acids, or bases, keep container tightly sealed and properly labeled
Special Sensitivity: Protect from moisture and extreme temperature fluctuations to maintain product potency and prevent degradation
Occupational Exposure Limits: No specific OSHA, ACGIH, or NIOSH limits for Neomycin Sulfate; minimize exposure using good workplace practices
Engineering Controls: Use local exhaust ventilation to reduce airborne dust, enclose processing steps if possible
Personal Protective Equipment: Use chemical-resistant gloves, safety goggles, protective clothing to reduce risk of skin and eye contact; in dusty conditions, use NIOSH-approved dust respirators
Hygiene Measures: Wash hands and exposed skin thoroughly after working with material, do not eat, drink, or smoke during handling
Appearance: White to slightly yellow, odorless, crystalline powder
Solubility: Highly soluble in water, low solubility in organic solvents like ethanol or ether
Odor: Odorless
Melting Point: Decomposes before melting
Boiling Point: Not applicable
pH (1% solution): 5.0 - 7.5
Partition Coefficient: Not available
Vapor Pressure / Density: Not volatile under normal conditions
Flash Point: Not flammable
Explosive Properties: Low risk, but dust can create air/dust mixture
Other Data: Stable under ordinary environmental conditions, hygroscopic
Chemical Stability: Stable at room temperature, protected from moisture and light
Conditions to Avoid: Exposure to excessive heat, open flames, sources of ignition, contact with incompatible chemicals
Incompatible Materials: Strong oxidizing agents, strong acids and bases
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon monoxide and carbon dioxide under fire conditions
Polymerization: No hazardous polymerization expected
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: May cause irritation to mucous membranes, skin, eyes; ingestion may affect gastrointestinal tract
Chronic Effects: Prolonged or repeated exposure can cause allergic reactions, particularly in sensitized individuals, potential for nephrotoxicity and ototoxicity with high or prolonged exposure in clinical situations
Symptoms: Rash, redness, skin sensitization, cough, breathing difficulties, abdominal pain, nausea, hearing loss in clinical misuse
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA or ACGIH
Reproductive Toxicity: No conclusive data, though animal studies suggest risk at high doses
Other Data: Systemic absorption through intact skin considered low; risk increases with injury or broken skin
Ecotoxicity: Neomycin Sulfate is toxic to aquatic organisms at low concentrations, may cause long-term adverse effects in aquatic environments
Persistence and Degradability: Product has low biodegradability in the environment, can persist and accumulate
Bioaccumulation Potential: Expected to be low due to molecular size and polarity, but not fully ruled out
Mobility in Soil: High mobility in water, may reach groundwater
Other Adverse Effects: Discharge to the environment should be avoided, since antibiotic residues can impact microbial ecology and antibiotic resistance patterns
Waste Disposal Methods: Dispose of as hazardous pharmaceutical waste in accordance with local, national, and international regulations, do not discharge to sewer or natural waters
Contaminated Packaging: Rinse containers, send to an authorized waste disposal facility, avoid recycling of containers used for this product
Additional Precautions: Work with institutional or industrial environmental health and safety officers to identify best disposal practices, provide clear labeling for any material destined for disposal
UN Number: Not regulated as a dangerous good under UN, DOT, IATA, or IMDG
Proper Shipping Name: Neomycin Sulfate
Hazard Class: Not classified as a hazardous material
Packing Group: Not assigned
Special Precautions for User: Handle sealed containers carefully during transport to prevent damage and potential leaks, keep original labeling intact
Environmental Hazards: Prevent release outside managed processes to reduce aquatic risks
Safety, Health, and Environmental Regulations: Subject to pharmaceutical drug control regulations, may be registered with national or regional agencies such as the US FDA, EMA, or equivalent
OSHA Hazards: Considered hazardous due to potential for allergic reactions and irritation
SARA Title III: Not listed as a hazardous substance
TSCA Inventory: Not listed as it is a drug product
International Inventories: Handled as a controlled substance for medicinal use, not a general industrial chemical
Additional Information: Ensure compliance with local occupational health and safety, environmental, and transport laws for storage and handling
