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Product Name: N-Propyl N-Butyrate
Chemical Name: Propyl butanoate
CAS Number: 105-66-8
Synonyms: Propyl n-butyrate, n-Propyl butyrate
Molecular Formula: C7H14O2
Molecular Weight: 130.19 g/mol
Uses: Commonly used as a flavoring agent and fragrance, found in the food, beverage, and cosmetic industries. Occasionally used as a solvent in chemical synthesis.
Supplier Details: Refer to attached supply chain documentation for company contact information, emergency telephone, and address.
GHS Classification: Flammable Liquids, Category 3
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor. May cause skin and eye irritation. Inhalation can cause dizziness, headache, or respiratory discomfort.
Pictograms: Flame (fire hazard), Exclamation Mark (irritant)
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Precautionary Statements: Keep away from heat, sparks, open flames, and hot surfaces. No smoking. Avoid breathing vapor or mist. Use only outdoors or in well-ventilated areas. Wear protective gloves and eye and face protection.
Chemical Name: N-Propyl N-Butyrate
CAS Number: 105-66-8
Concentration: 99% purity typical in commercial samples
Impurities: May contain trace levels of butyric acid and propanol depending on manufacturer
Other Information: Not formulated with any additives or stabilizers, supplied as a pure liquid ester.
Inhalation: Move exposed person to fresh air. Support breathing if needed. Seek medical attention if irritation, coughing, or symptoms persist.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water for at least 15 minutes. Seek medical advice if rashes or irritation appear.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Call for medical help if eye irritation continues.
Ingestion: Rinse mouth with water. Do not induce vomiting. Get medical attention immediately. Never give anything by mouth to an unconscious person.
Symptoms: Headache, dizziness, coughing, burning sensation in eyes or skin.
Suitable Extinguishing Media: Use dry chemical powder, foam, carbon dioxide, or water spray (fog only – full jet may spread fire).
Unsuitable Extinguishing Media: Do not use strong water jets as fire may spread.
Special Protective Equipment: Wear self-contained breathing apparatus and full protective clothing.
Hazards from Combustion: Produces carbon oxides (CO, CO2), irritating fumes, and smoke.
Firefighting Tips: Remove all ignition sources from area. Cool closed containers with water spray. Prevent runoff from entering drains or watercourses.
Personal Precautions: Evacuate area. Ventilate space. Avoid contact with skin, eyes, and inhalation of vapors. Eliminate all sources of ignition.
Protective Equipment: Chemical-resistant gloves, safety goggles, impervious clothing, NIOSH-approved respirator if ventilation is poor.
Environmental Precautions: Prevent spillage from entering waterways or soil. Contain and absorb leaks with inert material (sand, earth), transfer to safe containers for disposal.
Cleanup Methods: Use nonsparking tools. Avoid creating mist or vapor clouds. Dispose of according to local environmental regulations.
Handling: Handle in a chemical fume hood or well-ventilated area. Avoid directly breathing vapors or mist. Electrically ground and bond containers when moving liquids. Avoid contact with incompatible chemicals – especially strong oxidizers and acids.
Storage Conditions: Store in tightly closed containers made from compatible materials (glass, stainless steel). Keep in a cool, dry, and well-ventilated place, away from direct sunlight, sources of ignition, or heat.
Special Precautions: Store away from food and beverages. Do not reuse containers for other chemicals. Keep out of reach of children and untrained personnel.
Control Parameters: No OSHA PEL or ACGIH TLV established for this material; lower exposure by minimizing vapor/mist.
Engineering Controls: Local exhaust and general room ventilation required. Use explosion-proof electrical equipment.
Personal Protection: Wear chemical splash goggles and face protection, nitrile or butyl rubber gloves, laboratory coat or apron, and, if airborne concentrations reach unsafe levels, a NIOSH-certified organic vapor respirator.
Hygiene Measures: Wash hands, face, and any exposed skin before breaks and after handling. Remove contaminated clothing and wash before reuse.
Appearance: Colorless to pale yellow liquid
Odor: Fruity, pleasant, sweet (resembling pineapple or pear)
Odor Threshold: Not established
pH: Not applicable (neutral liquid)
Melting Point: -75°C
Boiling Point: 146°C
Flash Point: 36°C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid and vapor
Upper/Lower Flammability Limits: 1.2% (Lower); 7.4% (Upper) by volume in air
Vapor Pressure: 3 mmHg at 20°C
Vapor Density: 4.5 (air = 1)
Solubility: Slightly soluble in water; miscible with organic solvents
Partition coefficient (log Kow): 2.0
Auto-ignition Temperature: 410°C
Decomposition Temperature: No data
Viscosity: 0.74 mPa·s (20°C)
Chemical Stability: Remains stable under recommended handling, storage, and use conditions.
Possibility of Hazardous Reactions: May react with strong oxidizing agents, acids, or strong bases. Polymerization does not occur.
Conditions to Avoid: Elevated temperatures, open flames, sparks, hot surfaces, direct sunlight, static discharge.
Incompatible Materials: Strong oxidizing compounds, acids, and alkalis.
Hazardous Decomposition Products: Releases irritating fumes, carbon monoxide, carbon dioxide on combustion and thermal breakdown.
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion.
Acute Effects: Eye, skin, and respiratory tract irritation. Headache, nausea, dizziness from inhaling vapors.
LD50 (Oral, Rat): 9300 mg/kg
LD50 (Dermal, Rabbit): >5000 mg/kg
LC50 (Inhalation, Rat): Not available
Chronic Exposure: No data suggesting carcinogenicity, mutagenicity, or reproductive toxicity.
Other Information: Not listed by NTP, IARC, or OSHA as a carcinogen.
Ecotoxicity: Not classified as environmentally hazardous, but releases can harm aquatic life, especially in high concentrations. LC50 (fish, 96 h): >100 mg/L.
Mobility in Soil: Moderate mobility, may leach through soil to groundwater.
Persistence/Degradability: Expected to biodegrade readily in the environment. Estimated half-life ranges from several days to weeks.
Bioaccumulation Potential: Low bioaccumulation (log Kow 2.0); not expected to biomagnify across food chains.
Other adverse effects: Avoid contamination of water sources and sewers.
Waste Disposal Methods: Treat as hazardous waste. Follow all federal, state, and local environmental control regulations. Incinerate in a chemical incinerator equipped with afterburner and scrubber.
Container Disposal: Empty containers may hold residue. Do not reuse. Puncture and triple-rinse, then dispose by sanitary landfill or through a licensed waste management company.
Special Precautions: Avoid disposal into drains, surface water, or routine landfill. Notify authorities if a major spill enters natural waterways.
UN Number: UN 1993
Proper Shipping Name: Flammable Liquid, N.O.S. (N-Propyl N-Butyrate)
Transport Hazard Class: 3
Packing Group: III
Environmental Hazards: Not classified as marine pollutant.
Special Precautions: Use explosion-proof vehicles or containers. Label as flammable. Handle by trained personnel according to national/international transport regulations (DOT, IATA, IMO).
USA (TSCA): Listed on the Toxic Substances Control Act inventory.
OSHA Hazards: Flammable liquid, irritant.
EPCRA 311/312: Fire hazard, acute health hazard.
SARA 313: No components subject to reporting.
California Proposition 65: Not listed.
EU (REACH): Registered under EC no. 203-308-5.
GHS Classification: Flammable liquids, irritant.
Other Local Regulation: Refer to national and regional chemical safety and labeling regulations for handling and reporting requirements.
