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Product Name: N-Octanenitrile
Chemical Formula: C8H15N
Synonyms: 1-Cyanooctane, Octanenitrile
CAS Number: 629-86-1
Recommended Use: Laboratory chemical, organic synthesis intermediate
Manufacturer Information: Most chemical suppliers for industrial and research applications
Emergency Contact: Refer to local poison control centers and company emergency response numbers
GHS Classification: Acute toxicity oral (Category 4); Acute toxicity dermal (Category 4); Acute toxicity inhalation (Category 4)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, in contact with skin, or if inhaled; may cause respiratory and skin irritation
Pictograms: Exclamation mark (harmful), Health Hazard Schema
Precautionary Statements: Avoid breathing dust, fume, gas, mist, vapors, spray; Wash hands thoroughly after handling; Use only outdoors or in a well-ventilated area; Wear protective gloves, protective clothing, eye protection, face protection
Health Hazards: Toxic if ingested or absorbed through skin; central nervous system effects possible following exposure; may target respiratory system
Environmental Hazards: May cause short-term negative effects to aquatic life, potential for bioaccumulation
Specific Hazards: Volatile organic compound; flammable vapors may form explosive mixtures
Chemical Identity: N-Octanenitrile
Purity: Typically >98% for laboratory use
Impurities of Concern: Trace organic solvents, related nitriles
Common Additives: None in analytical grade
Component Contribution: Main toxicity and hazard arise from the nitrile group
Inhalation: Remove person to fresh air as soon as possible; support breathing with oxygen if available; seek immediate medical attention for symptoms like coughing or lack of consciousness
Skin Contact: Remove contaminated clothing and flush skin with water for at least 15 minutes; wash with soap and water after flushing; obtain medical advice if irritation develops
Eye Contact: Rinse eyes with water for several minutes while holding eyelids open; remove contact lenses if able; get medical attention if symptoms occur
Ingestion: Rinse mouth thoroughly; do not induce vomiting; never give anything by mouth to an unconscious person; seek medical attention immediately
Most Important Symptoms: Headache, dizziness, drowsiness, nausea, local skin and eye irritation; higher levels may cause respiratory difficulty or central nervous system depression
Immediate Medical Attention Required: Always call for professional help in case of acute exposure
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide; water spray for large fires
Fires to Avoid: Do not use direct water jet as it may scatter product
Fire Hazards: Vapors may form explosive mixtures with air above flash point; combustion generates toxic gases such as carbon monoxide, hydrogen cyanide, nitrogen oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, chemical protective suit; stay upwind
Special Procedures: Cool exposed containers with water spray; evacuate area and control sources of ignition
Personal Precautions: Evacuate area; ventilate space; wear gloves, protective clothing, eye and respiratory protection
Environmental Precautions: Prevent entry into drains, surface water or soil; report significant spillage to relevant authorities
Clean-up Procedures: Use non-sparking tools for collection; absorb with earth, sand, or non-combustible material; collect in sealed containers for disposal
Spill Response: Small spills – wipe with absorbent material; large spills – dike area and remove by explosion-proof pump
Safe Handling: Always use in a fume hood or well-ventilated space; keep away from open flames and hot surfaces; do not breathe vapors; minimize direct contact with skin and eyes
Precautionary Measures: Use spark-proof equipment; ground all containers during transfer; avoid buildup of static electricity
Storage Recommendations: Store in tightly closed containers in a cool, dry, well-ventilated location; segregate from strong acids, bases, oxidizers, and reducing agents; keep away from sunlight and ignition sources
Storage Class: Flammable liquid; toxic substance storage recommended
Occupational Exposure Limits: No established ACGIH TLV or OSHA PEL; keep exposure as low as possible
Engineering Controls: Chemical fume hood, eye wash station, emergency shower, local exhaust ventilation
Personal Protective Equipment: Nitrile or neoprene gloves, chemical splash goggles, lab coat, face shield, and in some cases, respirator for vapor protection
Workplace Practices: Always wash hands after handling; avoid eating, drinking, or smoking in work area; remove contaminated clothing before leaving workplace
Monitoring: Air monitoring for vapor concentrations recommended in industrial settings
Appearance: Colorless to pale yellow liquid
Odor: Mild, aliphatic scent
Odor Threshold: Not well-established
Melting Point: About -38 °C
Boiling Point: Around 191 °C
Flash Point: Approx. 83 °C (closed cup)
Density: About 0.81 g/cm³ at 20 °C
Solubility: Practically insoluble in water; soluble in organic solvents such as alcohol, ether
Vapor Pressure: 0.38 mmHg at 25 °C
Vapor Density: Heavier than air
Auto-ignition Temperature: Not determined
Partition coefficient (log Kow): Around 3.6 (hydrophobic)
Viscosity: Moderate, typical of medium-chain nitriles
Chemical Stability: Stable at room temperature under normal handling; sensitive to strong oxidizing agents
Reactivity: Can undergo exothermic reaction with acids, bases, and oxidizers; susceptible to hydrolysis under strong acidic or basic conditions
Hazardous Decomposition Products: Can produce toxic gases including hydrogen cyanide and nitrogen oxides during fire or intense heat
Polymerization: Not expected under standard conditions
Other Incompatibilities: Avoid alkali metals and strong reducing materials
Likely Routes of Exposure: Inhalation, ingestion, skin absorption, eye contact
Acute Toxicity Estimates: Oral LD50 (rat) approx. 400-1000 mg/kg; Dermal LD50 (rabbit) approx. 1500 mg/kg;
Irritation: Causes moderate skin and eye irritation; may provoke respiratory irritation
Chronic Effects: Long-term exposure may disrupt liver and kidney function; recurring exposure could increase sensitivity
Symptoms of Overexposure: Headache, drowsiness, respiratory distress, nausea; in severe cases, convulsions or collapse
Carcinogenicity: Not classified as carcinogenic by IARC or NTP
Mutagenicity and Reproductive Toxicity: No clear evidence in available studies
Ecotoxicity: Moderately toxic to aquatic life; acute LC50 (Fish, 96h): about 10-100 mg/L
Persistence and Degradability: Slow to degrade in water and soil; may persist in the environment
Bioaccumulative Potential: Expected to bioaccumulate due to hydrophobicity (log Kow > 3)
Mobility in Soil: Low water solubility and moderate vapor pressure limit extensive migration
Other Adverse Effects: Potential to disrupt aquatic organism metabolism; not classified as an ozone depleter
Waste Treatment Methods: Incinerate in approved chemical incinerator facility with afterburner and scrubber
Disposal of Product: Dispose of contents/container in accordance with local, regional, national, and international regulations
Disposal of Contaminated Packaging: Triple rinse and puncture before landfill or incineration by permitted facility
Special Precautions: Do not release to environment; keep records of disposal routes and batch numbers for traceability
UN Number: 2810
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (Octanenitrile)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III (harmful, less dangerous than I or II)
Environmental Hazards: Not a marine pollutant by IMDG criteria
Special Transport Precautions: Keep containers upright and secure; ensure clear hazard labeling
Additional Shipping Information: Comply with local carriage regulations and international agreements (ADR, ICAO/IATA, IMDG)
TSCA Inventory: Listed in the United States
REACH Registration: May require registration for import into the European Union
OSHA Hazards: Acute toxicity, skin and eye irritation
WHMIS Classification (Canada): D1B (Toxic), D2B (Irritant)
Other National Regulations: Subject to chemical control laws in many countries; SARA Title III Section 313 not listed
Labeling: Identify with all GHS required labels incl. hazard pictograms and precautionary statements
Workplace Safety: Follow all state and federal occupational safety laws regarding chemical exposure and training
