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Product Name: N-Isopropyl-N-Phenyl-Chloroacetamide
Chemical Family: Aromatic amide
CAS Number: 38041-04-0
Synonyms: 2-Chloro-N-(propan-2-yl)-N-phenylacetamide
Recommended Use: Laboratory reagents, chemical synthesis intermediate
Supplier: Indicate full company name, address, emergency phone
Emergency Contact Number: +1-800-XXX-XXXX
Classification: Acute toxicity—oral, dermal, and inhalation (Category 4); Skin irritation (Category 2); Eye irritation (Category 2A); Specific target organ toxicity - single exposure (Category 3)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, in contact with skin or inhaled; Causes skin and eye irritation; May cause respiratory irritation
Pictograms: Exclamation mark symbol for harmful substances
Precautionary Statements: Avoid breathing dust/vapors, wash thoroughly after handling, wear protective gloves, clothing, eye and face protection, do not eat, drink or smoke when using, use only outdoors or in well-ventilated area
Potential Health Effects: Irritation to skin, eyes, respiratory system; symptoms include headache, dizziness, nausea if inhaled or ingested
Chemical Name: N-Isopropyl-N-Phenyl-Chloroacetamide
Concentration: 95% or higher
CAS Number: 38041-04-0
Impurities: NMT 0.5% (specify if known)
Other Components: None
Inhalation: Move person to fresh air immediately, monitor for respiratory distress, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin thoroughly with plenty of soap and water, seek medical advice if irritation develops
Eye Contact: Flush with large amounts of water for minimum 15 minutes, remove contact lenses if present and easy to do, get medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, offer water to drink only if fully conscious, seek immediate medical treatment
Most important symptoms and effects: Redness, irritation, possible shortness of breath, gastrointestinal upset
Notes for physician: Treat symptomatically, monitor for possible airway compromise or allergic reaction
Suitable Extinguishing Media: Dry chemical, CO2, alcohol-resistant foam
Unsuitable Extinguishing Media: Never use water jet, may spread fire
Specific Hazards: May produce toxic fumes under fire conditions (hydrogen chloride, nitrogen oxides, carbon oxides)
Protective Equipment for Firefighters: Full protective suit, self-contained breathing apparatus
Firefighting Instructions: Evacuate area, stay upwind, cool exposed containers with water spray to prevent pressure build-up
Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide, nitrogen oxides
Personal precautions: Evacuate all non-essential personnel, wear respiratory protection, gloves, goggles, and protective clothing
Environmental precautions: Prevent spillage into drains, surface and ground water, notify competent authorities if entry occurs
Methods for Containment: Cover spill with inert absorbent material (sand, earth, vermiculite), sweep up and transfer to a labeled container for proper disposal
Clean-up Procedures: Wash spill site after material pick-up, ventilate area, avoid raising dust
Handling: Handle in a chemical fume hood, avoid breathing dust or vapor, prevent skin and eye contact, use only non-sparking tools
Storage: Keep in tightly closed containers, store in a cool, dry, and well-ventilated location; segregate from oxidizers and acids
Storage Temperature: Recommended 2–8°C (Refrigerated)
Keep Away From: Heat, open flames, strong oxidizing agents, strong acids
Incompatible Materials: Strong oxidizing agents, acid chlorides, acid anhydrides
Special Storage Consideration: Protect container from physical damage and moisture
Exposure Limits: No established occupational limits for this compound, minimize exposure
Engineering Controls: Use with adequate local exhaust ventilation, chemical fume hood required
Personal Protective Equipment: Nitrile gloves, safety goggles, lab coat, suitable respirator in absence of proper ventilation
Hygiene Measures: Do not eat, drink, or smoke during use, wash hands thoroughly after handling
Environmental Exposure Controls: Use spill control and containment systems, avoid ecosystem discharge
Appearance: Off-white to beige crystalline solid
Odor: Mild aromatic odor
Odor Threshold: Not established
Molecular Formula: C11H14ClNO
Molecular Weight: 211.69 g/mol
Melting Point: 74–77°C
Boiling Point: Decomposes before boiling
Density: Approx. 1.15 g/cm³ at 25°C
Solubility: Low solubility in water; soluble in organic solvents such as ethanol, methanol, acetone
Vapor Pressure: Negligible at room temperature
pH: Not applicable
Partition Coefficient (log Kow): Not determined
Flash Point: Not established
Autoignition Temperature: Not determined
Decomposition Temperature: Not available
Evaporation Rate: Not determined
Upper/Lower Flammability Limits: Not established
Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: High ambient temperature, moisture, open flame
Reactvity: May react with strong oxidizers, acids, reducing agents
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon oxides
Polymerization: Not expected under normal handling
Incompatible Materials: Oxidizing agents, strong acids
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin; LD50 data unavailable but toxicity anticipated based on chemical similarities
Skin Corrosion/Irritation: Causes skin irritation on contact
Serious Eye Damage/Irritation: Will cause moderate or severe eye irritation
Respiratory Sensitization: May cause respiratory irritation, cough, or difficulty breathing
Skin Sensitization: No data available, but recommend caution
Carcinogenicity: Not classified by IARC or NTP
Reproductive Toxicity: No available studies; handle with care
Specific Target Organ Toxicity: May cause drowsiness, nausea, or headache from short term exposure
Aspiration Hazard: No indication of aspiration toxicity
Ecotoxicity: Data not available for aquatic or terrestrial organisms; structurally similar chemicals show toxicity to aquatic invertebrates
Persistence and Degradability: Persistent under normal environmental conditions; unlikely to undergo rapid biodegradation
Bioaccumulative Potential: Potential for bioaccumulation based on partition coefficient of related compounds
Mobility in Soil: Likely moderate to low mobility due to organic solubility
Other Adverse Effects: Avoid discharge to environment, potential risk of toxicity
Waste Treatment Methods: Collect spillage and dispose of in a chemical waste container using a licensed contractor
Product Disposal: Incinerate in accordance with local, state, and federal requirements; do not discharge to drain or natural waterways
Container Disposal: Triple rinse containers, puncture, process through approved waste disposal contractor
Special Precautions: Contact waste disposal authority for guidance; classify as hazardous waste
UN Number: Not assigned
UN Proper Shipping Name: Not regulated as hazardous for transportation in small laboratory quantities
Transport Hazard Class: Not assigned
Packing Group: Not determined
Marine Pollutant: Not established
Transport Precautions: Transport in a tightly closed container, protected from physical damage and temperature extremes, ensure labeling meets regulations
Special Transport Notes: Handle according to chemical safety guidelines at all times
OSHA Hazard Communication: This product meets criteria for hazardous chemicals, subject to reporting under OSHA HazCom Standard
TSCA Inventory: Check product status for inclusion on US Toxic Substances Control Act Inventory
SARA Title III: Not known to be subject to reporting under Sections 302, 304, 313
California Proposition 65: Not listed, though handle as chemical of unknown hazard
WHMIS (Canada): D2B – Toxic Material Causing Other Toxic Effects
Other National or International Regulations: Check compliance with local, state, national, and int'l regulations; workplace and laboratory safety protocols apply
