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Product Name: N-Acetyl-DL-Leucine
Synonyms: Acetyl-DL-leucine, AcDLLeu
Chemical Formula: C8H15NO3
Molecular Weight: 173.21 g/mol
CAS Number: 7523-51-7
Manufacturer: Listed by supplier or manufacturer information
Recommended Use: Laboratory reagents, research and chemical synthesis
Emergency Contact: Refer to local supplier data, poison control center, or regulatory listing.
Classification: Not classified as hazardous under GHS standards
Hazard Statements: May cause mild irritation to respiratory system, eyes, and skin on direct contact
Pictogram: None for general use; consult workplace safety requirements
Signal word: None required
Precautionary statements: Use personal protective equipment, avoid dust formation, wash hands after handling, prevent inhalation of dust or particulates
Health Effects: Inhalation or ingestion may cause mild irritation
Chemical Name: N-Acetyl-DL-Leucine
CAS Number: 7523-51-7
Concentration: ≥98% (by weight)
Impurities: Trace solvent residues, unreacted precursors, moisture content (specific values depend on manufacturer and batch analysis)
Inhalation: Remove to fresh air, keep comfortable for breathing, seek medical attention if symptoms persist
Skin Contact: Wash exposed area thoroughly with soap and water, remove contaminated clothing
Eye Contact: Flush eyes with plenty of water for at least 15 minutes, call for medical assessment if irritation continues
Ingestion: Rinse mouth, give water to drink if person is conscious, seek medical advice if feeling unwell
Symptoms: Minor irritation to mucous membranes or skin possible
Advice for Medical Professionals: Treat symptomatically
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, foam
Specific Hazards: Combustion may release CO, CO2, and nitrogen oxides
Protective Measures: Wear self-contained breathing apparatus and protective clothing
Special Procedures: Cool containers with water source to prevent rupture, avoid inhaling combustion products
Firefighting Equipment: Standard fire service PPE and breathing apparatus
Personal Precautions: Use personal protective gear, avoid breathing dust, ensure adequate ventilation, keep unprotected people away
Spill containment: Avoid spill contact with water systems and drains, prevent further spread
Clean-Up Methods: Collect powder by mechanical means, sweep or vacuum, place in labeled containers, clean area with water and detergent
Waste Disposal: Refer to disposal section for local regulations
Environmental Considerations: Avoid release to environment, especially water streams
Handling: Use in well-ventilated area, minimize dust formation, avoid contact with skin and eyes, wash hands after handling
Storage Conditions: Store in cool, dry, well-ventilated area, avoid exposure to sunlight, keep tightly closed
Incompatible Materials: Strong oxidizing agents, acids, bases
Shelf Life: Refer to manufacturer for recommended storage period
Specific End Use: Research, laboratory, formulation work; follow institutional guidelines for safe handling
Occupational Exposure Limits: No occupational exposure limits set by OSHA, ACGIH, or NIOSH for N-Acetyl-DL-Leucine
Engineering Controls: Local exhaust ventilation recommended, dust capture systems advised
Personal Protective Equipment: Protective clothing such as laboratory gowns or coats, nitrile or latex gloves, chemical splash goggles, dust masks or particulate respirators
Hygiene Measures: Wash thoroughly after handling, remove and wash contaminated clothing before reuse
Environmental Exposure Controls: Prevent product release into water, soil, or drains unless in compliance with regulations
Appearance: White to off-white crystalline powder
Odor: Odorless or faint chemical odor
Melting Point: 145–148°C (manufacturer test data may vary)
Boiling Point: Not applicable, decomposes under extreme heat
Solubility: Freely soluble in water, sparingly soluble in ethanol
pH: 5.0–7.0 (for 1% aqueous solution)
Vapor Pressure: Negligible
Partition Coefficient: logP value around 0.06 (literature estimate)
Specific Gravity: Approximately 1.2 (solid bulk)
Flash Point: Not established
Flammability: Not flammable under normal working conditions
Evaporation Rate: Not applicable
Chemical Stability: Stable under standard temperatures and pressures
Reactive Conditions: Excessive heat or light, exposure to strong oxidizers or acids
Decomposition Products: May produce carbon oxides, nitrogen oxides on thermal decomposition
Polymerization: No hazardous polymerization expected
Incompatible Substances: Avoid strong oxidants, acids, bases
Acute Toxicity: No acute toxicity data published for humans; animal pharmacological data indicate low acute toxicity profile at typical laboratory doses
Skin Irritation: Low risk; slight irritation possible upon repeat or prolonged contact
Eye Irritation: Mild irritation may occur upon contact
Inhalation Risk: Dust may cause respiratory discomfort or minor cough
Sensitization: No evidence for skin sensitization noted
Chronic Effects: No data indicating carcinogenic, mutagenic, or reproductive hazards
Exposures: Intended for controlled laboratory or research use, not for food, drug, or household application without further assessment
Ecotoxicity: No substantial aquatic toxicity data; based on structure, predicted low hazard to aquatic organisms at environmental concentrations
Persistence and Degradability: Appears biodegradable, related substances metabolized in natural settings
Bioaccumulation: Unlikely due to high water solubility, low logP value
Mobility in Soil: Expected to have moderate to high mobility in aqueous environments
Additional Notes: Avoid uncontrolled release due to unknown influence on microbial or aquatic communities
Waste Treatment Methods: Dispose by incineration at licensed waste disposal facility where permitted, chemical residues must not be released to sewer
Packaging Disposal: Rinse empty containers, remove labels if possible, follow chemical waste procedures
Local Disposal Rules: Must comply with hazardous residue disposal rules, refer to national or regional regulatory agency
Special Precautions: Contain spills promptly to avoid environmental discharge
UN Number: Not regulated for transport
Transport Hazard Classification: Not hazardous according to IATA, ADR, IMDG
Packaging Requirements: Use tightly sealed original containers, protect from moisture and physical damage
Special Transport Precautions: Keep upright, avoid impact, secure containers to avoid spillage
Bulk Transport: Not specified for bulk handling by regulation; follow laboratory or institutional guidelines
Labelling: Not required for consumer markets, specific workplace labelling may apply
GHS Classification: Not classified as hazardous
OSHA/NIOSH/ACGIH: No specific exposure limits
REACH/CLP: Not listed as substance of very high concern
Other Regional Regulations: Review applicable chemical inventories and country-specific restrictions before import, purchase, or use
