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Product Name: Moxifloxacin Hydrochloride
Chemical Formula: C21H24FN3O4·HCl
CAS Number: 186826-86-8
Synonyms: Avelox, BAY 12-8039 HCl
Recommended Use: Active pharmaceutical ingredient (API) for antibacterial medications
Supplier Contact Information: Manufacturer’s name, address, and emergency contact phone number listed on packaging and shipping documents
GHS Classification: Acute toxicity (oral and inhalation category 4), Eye irritation (category 2A), Skin sensitization (category 1)
Pictograms: Exclamation mark symbol for irritation and sensitization hazards
Signal Word: Warning
Hazard Statements: May cause allergic skin reaction, may cause eye irritation, harmful if swallowed or inhaled
Precautionary Statements: Avoid breathing dust, use gloves, use eye protection, wash hands thoroughly after handling
Chemical Name: Moxifloxacin Hydrochloride
Concentration: 98%+ (typical for pharmaceutical grade)
Impurities: Trace related substances from synthesis, typically below 0.1%
Molecular Weight: 437.9 g/mol
Form: Crystalline powder or solid
Inhalation: Move to fresh air, monitor breathing, seek medical help if symptoms develop
Skin Contact: Remove contaminated clothing and rinse skin with water, use soap if irritation appears
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, seek medical attention if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, seek prompt medical attention
Medical Notes: Show MSDS to healthcare provider for guidance
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide or foam
Unsuitable Extinguishing Media: Strong water jets may spread powder
Fire Hazards: Possible emission of toxic fumes (hydrogen chloride, nitrogen oxides, carbon oxides, and fluorinated gases) during combustion
Protective Equipment: Self-contained breathing apparatus and full protective gear
Special Procedures: Prevent runoff, ventilate area, keep dust to minimum
Personal Precautions: Wear gloves, face shield, respirator for dust
Spill Procedures: Avoid dust generation, sweep or vacuum up material
Environmental Precautions: Prevent entry into sewers and waterways
Cleanup Methods: Use damp cloths, collect and place in secure container for disposal following regulations
Safe Handling: Use local exhaust ventilation, handle in well-ventilated areas, avoid skin and eye contact, avoid inhaling dust
Storage Conditions: Store in tightly closed containers, keep at 2–8°C, protect from moisture, light, and incompatible materials
Incompatibilities: Strong oxidizers, bases, and acids
Engineering Controls: Laminar flow hoods, dust extraction, negative pressure rooms
Personal Protective Equipment: Nitrile gloves, laboratory coats, protective safety glasses with side shields, appropriate respiratory protection in the absence of adequate ventilation
Hygiene Measures: No eating, drinking, or smoking near handling area; wash hands and face after work; dispose of contaminated clothing properly
Occupational Exposure Limits: Limits not established specifically for moxifloxacin hydrochloride; handle as a pharmaceutical-grade hazardous compound
Appearance: Yellow to light yellow crystalline powder
Odor: Odorless or slight chemical odor
pH (1% solution): 4–6
Solubility: Freely soluble in water, sparingly soluble in methanol
Melting Point: 220–230°C
Vapor Pressure: Not measurable at standard conditions
Boiling Point: Not applicable (decomposes before boiling)
Molecular Weight: 437.9 g/mol
Partition Coefficient (log P): –0.43 (estimated)
Bulk Density: 0.45–0.60 g/cm³
Chemical Stability: Stable under recommended storage conditions
Incompatible Materials: Strong oxidizers and acids may react violently
Conditions to Avoid: High temperatures, humidity, exposure to light
Hazardous Decomposition Products: Hydrogen chloride, fluorinated organic compounds, nitrogen oxides, carbon oxides
Polymerization: Does not occur under normal laboratory or warehouse conditions
Acute Toxicity: Oral LD50 in rats approximately 1500 mg/kg; inhalation and dermal toxicity not fully characterized in humans
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Symptoms of Overexposure: Nausea, dizziness, headache, allergic skin reactions, eye irritation, gastrointestinal upset
Sensitization: Skin sensitizer in susceptible individuals
Carcinogenicity: No evidence of cancer risk in animal studies, not listed as a carcinogen by IARC or NTP
Other Effects: May cause photosensitivity and mild liver enzyme elevations
Aquatic Toxicity: Toxic to aquatic life at low concentrations, chronic exposure can affect organisms such as daphnia, algae, and fish
Persistence and Degradability: Not readily biodegradable, may persist in water and soil
Bioaccumulation Potential: Low potential, but monitoring in pharmaceutical waste is necessary
Mobility in Soil: Moderate; risk of groundwater contamination near production or waste disposal sites
Other Adverse Effects: Active pharmaceutical ingredients can disrupt microbial communities in the environment
Disposal of Product: Must be disposed of as hazardous pharmaceutical waste, in accordance with local, state, and national regulations
Waste Container Requirements: Use sealed, labeled chemical waste containers; prevent leaks or contamination
Handling Contaminated Packaging: Rinse containers thoroughly before recycling or disposal; treat as chemical waste
Incineration: Preferred method for destruction under controlled conditions; not for disposal in regular landfill or sewage systems
UN Number: Not assigned for pharmaceutical substances not classified as dangerous goods
Transport Hazard Class: Not regulated by ADR, IMDG, or IATA
Packing Group: Not applicable for non-dangerous drug substances
Proper Shipping Name: Moxifloxacin Hydrochloride, API
Special Precautions: Keep containers tightly sealed during transit, avoid breakage and spillage, handle with care in accordance with good distribution practices for pharmaceuticals
Regulatory Status: Prescription drug substance; regulated under FDA, EMA, and other national drug laws; not a controlled substance
OSHA Status: Not specifically regulated as a hazardous chemical
TSCA / REACH / DSL: Not listed as a commercial chemical; exemptions may apply for approved pharmaceuticals
Environmental Regulations: Subject to discharge limits under pharmaceutical waste frameworks
Other Notes: Handle and dispose according to Good Manufacturing Practice (GMP), workplace safety, and environmental requirements; specific regulations and guidance available from regulatory authorities
