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Moxifloxacin Hydrochloride: A Deep Dive into an Essential Antibiotic

Historical Development

Moxifloxacin hydrochloride arrived after a long journey of scientific persistence. The story begins in the late twentieth century with waves of new antibiotics emerging to tackle infections that shrugged off older drugs. Researchers chased the fluoroquinolone class for its knack at stopping bacterial DNA replication. Different pharmaceutical teams spent years tweaking chemical structures, searching for a mix with strong bacteria-fighting power and minimal side effects. Moxifloxacin started out in labs as a modification on earlier fluoroquinolones, getting its first broad medical use around 1999. Doctors and scientists saw how it fought a wide variety of bacteria, making it useful for both community-acquired and hospital infections. The timeline shows a steady improvement on side effects and dosing, thanks to this deliberate chemical engineering. Over time, it became a staple in clinics for tough respiratory and intra-abdominal infections where older drugs failed.

Product Overview

Moxifloxacin hydrochloride enters the market mainly as tablets, intravenous solutions, and eye drops. Most people meet it in hospitals or pharmacies labeled for the treatment of lower respiratory tract infections, acute bacterial sinusitis, skin infections, and conjunctivitis. Each dose contains the active salt form combined with inert ingredients to make the product stable and easy to use. Leading brands put out products with clear instructions for doctors and patients. Unlike some other antibiotics that the body flushes out quickly, this compound keeps its levels in the body long enough that people only need it once a day. For many, that bit of convenience and reliable action means better compliance to complete their prescription. Companies often highlight its broad spectrum, picking up gaps where penicillins or macrolides can’t reach. Doctors value it for patients who need a switch from oral to intravenous forms during hospital care.

Physical & Chemical Properties

Looking at moxifloxacin hydrochloride as a raw chemical, it takes the form of a bright yellow, crystalline powder. The substance dissolves easily in water, thanks to its hydrochloride salt, an important property for intravenous and oral use. The molecular formula is C21H25ClFN3O4·HCl, weighing in at about 437.9 g/mol for the base plus the hydrochloride part. This molecule packs a fluorine, a chlorine, and a bulky side chain, which lets it punch through bacterial cell membranes and stop DNA gyrase—crucial for its action. It melts at about 225°C with some decomposition, demanding care in storage and handling. The product resists breakdown under routine hospital handling and holds up well under normal lighting. Pharmaceutical manufacturers measure and control impurities tightly, because even small changes can make a big difference in patient outcomes or side effect profiles.

Technical Specifications & Labeling

Good label design on moxifloxacin hydrochloride isn’t just a regulatory checkbox. Accurate information about dosage strength, route, and lot number means everything in emergencies. Most vials or strip packs list doses like 400 mg per tablet or 20 mg/mL for injections, along with storage details—usually below 25°C, away from moisture. Strength, expiration, manufacturer data, registration number, and usage instructions must all line up with local and international regulators like the FDA or EMA. Time and again, cases prove how tiny errors in labeling can lead to overdoses, allergic reactions, or wasted stock. Hospitals that keep clear track of inventory and labeling history trim avoidable mistakes. Pharmacies and clinics hold technical sheets giving full details on each batch, right down to analytical test results for compliance.

Preparation Method

Producing moxifloxacin hydrochloride means architects in the lab bench running a mix of organic synthesis steps. Most routes use a fluoroquinolone core scaffold made from readily available starting materials. Scientists introduce substitutions including methoxy or amino groups through controlled reactions—sometimes with chromium-based or palladium catalysis—in inert atmosphere conditions. Once the main skeleton forms, chemists purify it by crystallization or chromatography, pressing out unwanted by-products. The last steps add the hydrochloride salt by bubbling dry hydrogen chloride or adding hydrochloric acid to a solution of the free base, causing the salt to crash out as a solid. The powder dried under vacuum reaches pharmaceutical-grade purity. For injectables, another round of sterilization and filtration follows. Production lines rotate through many careful cleaning stages between batches, since cross-contamination spells big problems for patient safety.

Chemical Reactions & Modifications

Moxifloxacin’s fluoroquinolone backbone tolerates a fair bit of chemical change without losing punch. Medicinal chemists spend hours swapping side groups, altering solubility and bug-killing power, hoping to dodge rising resistance. One corner of research involves making prodrugs to release moxifloxacin only after reaching particular tissues, reducing side effects. In lab conditions, acidic or alkaline hydrolysis cleaves the compound, although it stands up well to digestion in the stomach and gut. Some teams add bulky or charged groups to see if new versions work against strains that ignore the parent molecule. While the main molecule remains the backbone in pharmacy aisles, hundreds of analogs compete in preclinical tests each year. Every small change, though, needs close study—small chemical shifts can spark unexpected allergies, toxicity, or poor absorption in humans.

Synonyms & Product Names

Pharmacists see moxifloxacin hydrochloride on shelf bottles paired with a whole registry of trade names. Common alternatives include Avelox and Vigamox, branded by different companies. Many generic versions reach clinics globally under government registration codes. Synonyms—like BAY 12-8039 or simply moxifloxacin HCl—circulate in research and supplier catalogs. This variety sometimes bruises communication in busy hospitals when a staff member only knows a product by its brand name. Recording, prescribing, and dispensing show fewer mix-ups once everyone learns the chemical core matches across labels. In scientific writing, the International Nonproprietary Name (INN) keeps things universal—in this case, moxifloxacin hydrochloride.

Safety & Operational Standards

No matter the advances in design, moxifloxacin hydrochloride brings risks when basic safety protocols fall short. Healthcare workers need gloves and eye shields when handling the raw powder in production environments since dust can irritate skin and airway. Hospitals keep it away from children, holding stocks in locked cabinets due to the risk of overdose or accidental ingestion. The product’s label always clearly notes not to use in patients with allergies to quinolones. Drug guides flag known interactions—some antacids, heart rhythm drugs, and blood thinners shift how the drug moves through the body. The molecule can lengthen the QT interval on the heart’s electrical system, so doctors avoid it in people with certain arrhythmias. Training and clear checklists remain the best shield against mistakes. Over-the-counter availability without prescription never appears in responsible systems. Waste protocols call for specific chemical disposal rather than general trash, steering clear of waterway contamination.

Application Area

Moxifloxacin hydrochloride’s strongest suit lands in fighting bacterial lung infections like pneumonia, acute bronchitis, and complex sinusitis. Doctors also lean on it for skin and soft tissue infections where more basic types won’t work. In ophthalmology clinics, moxifloxacin appears in eye drop form tackling bacterial conjunctivitis, especially for strains evading older antibiotics. Gastroenterologists use it off-label for intra-abdominal infections, sometimes mixed with other drugs to cover a patchwork of bug types. Because of convenience and reliable body concentrations, doctors trust it in patients shifting from hospital to home care. Standard guidelines caution against casual use for lighter infections, keeping resistance levels in check for cases where its broad power is truly needed. The strength and reach of moxifloxacin, matched with careful use, lengthen its effective life in the medical toolkit.

Research & Development

Laboratories worldwide keep a steady focus on moxifloxacin, both to safeguard its effectiveness and stretch its use into new frontiers. Current studies chase lower-cost generics, improved coatings for extended shelf-life in hot climates, and nano-forms that could bring steadier drug release over days instead of hours. Some research follows how best to combine it with other antibiotics in short bursts, cutting down overall use and holding resistance at bay. Teams also test diagnostic tools that pinpoint exactly when moxifloxacin is the right choice, trimming down on unnecessary exposure. Increasing genetic surveillance of hospital bacteria tracks upswings in resistance, flagging trouble before it spreads. Most medical conferences give space to new findings on safety, outcomes, and smarter deployment strategies. Beyond infection, scientists watch for roles in preventing post-surgical complications and chronic lung issues where bacteria have dug in deep.

Toxicity Research

During its approval and beyond, moxifloxacin hydrochloride needed a close look at toxicity for both expected and rare problems. Animal studies map out doses that damage the liver, kidneys, or cause nervous symptoms when levels run too high. Testing in several species has shown a predictable safety window, supporting its single daily dosing in adults. Human cases have occasionally turned up rare tendon rupture or psychiatric effects, especially in people over sixty or on steroids. Dose adjustments are a must in patients with kidney or liver problems, since slower breakdown leads to buildup and higher risk. Surveillance networks in many countries post alerts for new or serious side effects, pushing regular updates to hospital treatment lists. Antidotes or medical monitoring protocols exist in major centers for the rare but serious chance of heart rhythm disturbance. Patients get clear instructions to watch for symptoms and report back early, driving safer use in the community.

Future Prospects

As resistance to older drugs inches up, moxifloxacin hydrochloride stands at a crossroads. The path forward rests on smart stewardship—using it only for tough or high-risk infections—matched to continued innovation in delivery and chemistry. Fast, portable diagnostic tools may become routine, helping clinics pick exactly when moxifloxacin is needed. Next-generation versions with tweaks to beat resistance, reach hidden tissue, or dodge side effects sit in research pipelines. Cheaper manufacturing and global partnerships boost access in places where bacterial infections still kill in large numbers. Policies that support mandatory reporting, environmental safety, and research funding keep the drug useful well into future decades. The same careful attention that brought it from lab to hospital bed will keep it working against tomorrow’s bacterial threats.




What is Moxifloxacin Hydrochloride used for?

The Role of Moxifloxacin in Treating Tough Infections

Sitting in a doctor’s office with a nagging cough, or maybe a fever that just won’t quit, is an experience many people share. Some infections brush off basic treatments. That’s where moxifloxacin hydrochloride comes into play. This antibiotic belongs to the fluoroquinolone class, and doctors often prescribe it when they need a medication that pulls its weight against bacteria that don’t back down easily.

How Moxifloxacin Steps Up

This drug is known for punching back against respiratory tract infections such as pneumonia and bronchitis. People struggling with these issues often have tried other antibiotics with little luck. In real-world hospitals, nobody wants to take chances with infections traveling deep into lungs or sinuses. Moxifloxacin covers a broad range of bacteria, including some strains that show resistance to other common antibiotics. That power proves especially important in treating community-acquired pneumonia and severe sinus infections.

Eye infections present another battle. Doctors count on moxifloxacin eye drops for bacterial conjunctivitis (pink eye). From my own experience speaking with physicians, prescriptions show up frequently during the back-to-school months, as kids pass around eye bugs like candy.

The Importance of Responsible Use

Antibiotic resistance isn’t just a buzzword from medical headlines—it’s something doctors and patients face in real time. Overuse and misuse of drugs like moxifloxacin create stronger, tougher bacteria. These “superbugs” leave fewer treatment options for serious infections. In the case of moxifloxacin, it’s saved for situations where other treatments don’t do the trick or where medical guidelines clearly point to it as the best choice.

Hospitals often use moxifloxacin as a tool against infections that come with high stakes. For example, in diabetic foot infections or certain skin and abdominal infections, doctors need to act fast. Moxifloxacin can be part of that plan because of its strength and ability to tackle multiple types of bacteria. That reach makes it valuable, yet it also puts pressure on every link in the chain—from pharmacists to patients—to follow dosing and duration instructions to the letter.

Safety, Risks, and Solutions

No antibiotic comes without side effects. I know people who developed mild diarrhea or an upset stomach. The list doesn’t stop there; rare but serious problems like tendon rupture and changes in heart rhythm can also show up. For people with a history of heart issues or who take certain medications, open discussions with a healthcare provider matter. Factoring these risks means not jumping to the strongest antibiotic option unless it really fits the case.

Doctors and pharmacists often talk about the need for more education. Patients feel pressure to ask for strong medications, hoping for a quick recovery. The solution starts with clear communication. Patients can help by sharing their full medical history and asking doctors why a specific drug shows up on their treatment list. Providers can keep moxifloxacin in reserve for situations where it delivers the biggest benefits.

Looking Forward

Every time a prescription pad tears off a sheet for moxifloxacin, it’s a result of a careful judgment call. The antibiotic brings relief when used at the right moment, against bacteria that threaten to cause real harm. As new resistance patterns emerge and as researchers search for fresh solutions, sticking to smart, targeted use of antibiotics like moxifloxacin keeps options open for everyone.

What are the common side effects of Moxifloxacin Hydrochloride?

Moxifloxacin and Its Uses

Moxifloxacin Hydrochloride comes up when dealing with stubborn bacterial infections. This antibiotic finds a role in treating respiratory tract infections, sinus infections, and some cases of skin infections. People pick it when other antibiotics have failed or when guidelines suggest something stronger than amoxicillin or azithromycin. Like every powerful medicine, it brings benefits but also a handful of drawbacks.

GI Troubles and Stomach Upset

After taking moxifloxacin for a sinus infection that wouldn’t go away, I noticed a telltale gurgling in my stomach. Nausea, diarrhea, and minor stomach pain arrived within days. This isn’t rare. Studies published by the FDA and peer-reviewed journals show that up to 10% of patients taking moxifloxacin deal with similar digestive effects. Most of these symptoms fade by the time the prescription runs out, but they do make a rough infection even less pleasant.

Headaches and Dizziness

It’s common to read patient reviews describing headaches or dizziness. As moxifloxacin passes into the brain, some people feel unusually lightheaded or complain that their head hurts. This affects daily activities and may be dangerous if people drive or operate machinery. Researchers from the Annals of Pharmacotherapy found that up to 6% of users experience these effects. Those numbers might sound small, but when you’re already run down, any new symptom stands out.

Allergic Reactions and Skin Issues

Rare but serious side effects can include swelling, itching, and rashes. Hives have been reported. In my practice, I’ve seen one case where a patient’s lips swelled. If this happens, people should seek help fast because allergic reactions can turn life-threatening. The CDC warns that although these cases don’t come up often, the high stakes mean doctors and patients need clear information.

Effects on Tendons and Joints

Moxifloxacin falls under the fluoroquinolone class, flagged by the FDA for causing tendonitis and tendon rupture in rare situations. Someone who’s older or on steroids faces extra risk. Reports of sudden pain or snapping sounds in the Achilles tendon have cropped up in clinics and emergency rooms. This complication stays on my mind for older patients or anyone heavy on physical activity. Awareness helps: if muscle or joint pain comes up, people should stop the drug and call their doctor. This message appears in the medication’s black box warning because the risk, though rare, is serious.

Heart Rhythm Changes

Some antibiotics send the heart’s electrical system into a brief spin, and moxifloxacin is one of them. It can lengthen the QT interval, raising the chance of dangerous arrhythmias. Most healthy adults skate by without a blip on their EKG, but someone with heart conditions or on other rhythm-altering drugs needs a check-in with their doctor. The American Heart Association published guidelines reminding professionals to watch out for these situations, since the risk grows with dose or drug combinations.

Supporting Patients: Practical Next Steps

Doctors and pharmacists have a job not just to prescribe moxifloxacin, but to walk patients through the list of possible side effects. Simple directions―taking the drug with food or fluids, knowing when to rest, or watching for warning signs―keep patients safer. People need easy access to information, not just dense printouts. Pharmacists can point out red flags and helplines. Digital health records could flag drug interactions and heart risks, acting as a safety net for everyone involved.

How should I take Moxifloxacin Hydrochloride?

Understanding What’s in Your Hand

Moxifloxacin hydrochloride comes up a lot in conversations about antibiotics, especially when folks talk about tough infections. It's not a home remedy, but a prescription pill meant to fight bad bacteria. Doctors won’t hand this out for sniffles or regular coughs. They save it for things like sinus infections, pneumonia, or when other medicines strike out. It works because it blocks the way bacteria grow and multiply. Misusing it helps nothing — it just gives those germs a chance to learn new tricks and get stronger.

The Basics: Dosage & Timing

One thing my own doctor made clear: do not play guesswork with antibiotics. If the label says take one tablet each day, take just one. Not two, not whenever you remember. I’ve seen people stop halfway because they “felt better.” The problem comes back swinging, sometimes with extra firepower. Swallow the tablet whole with water — don’t chew or crush it. If you take it around the same time every day, it’s easier to remember and lets the medicine do its job without interruption. Meals aren’t a big concern, but empty stomachs can crank up side effects like nausea. So, I’d have it with a late breakfast or even after a sandwich, taking the edge off any queasiness.

What to Avoid: Interactions and Missed Doses

Calcium and antacids throw a wrench in the works. If you drink milk, take supplements with magnesium or aluminum, or pop antacids, leave a gap — at least six hours after or two hours before you swallow Moxifloxacin. These extras can block absorption and mess up the results. Accidentally skipping a pill happens. If there’s plenty of time before your next dose, go ahead and take it. If you remember close to the next one, let it go — double-dosing just risks side effects. Juggling pills on your own, especially if there’s confusion, doesn’t bring good results. Pharmacists and doctors prefer a call over a home-spun fix.

Recognizing Side Effects Early

Antibiotics come with warnings. With Moxifloxacin, stomach upset, headaches, or feeling lightheaded might show up. In my circles, people have mentioned their tendons felt sore or they developed a rash. Tendons hurting — especially in the leg or shoulder — call for a stop and a fast call to the doctor. Allergic reactions may pop up as hives, swelling, or trouble breathing. Even if you think, “It’ll pass,” report it immediately. That’s not stubbornness; that’s just playing with fire.

Fighting Resistance and Using It Wisely

I can’t count the times folks in my community asked for “just-in-case” antibiotics. Handing out Moxifloxacin for minor aches or viral infections is part of why there are superbugs now. Taking meds only as prescribed — no saving pills, no sharing with others — actually keeps antibiotics effective for everyone. It’s a group effort. Each time someone skips directions, resistant bacteria win a round. I’ve seen the outcome in hospital wards, with infections that no longer budge for regular treatment.

Seeking Real Help, Not a Shortcut

No online tip can replace advice from someone who knows your health inside out. If questions pile up or symptoms don’t fade, a chat with the prescribing doctor or a pharmacist is the best way to go. Stick to the full course. Trust the plan set out in that little white bag. It could mean faster recovery, fewer complications, and for the big picture, it gives antibiotics a fighting chance in the future.

Are there any important warnings or precautions for Moxifloxacin Hydrochloride?

The Risks Hidden Behind a Powerful Antibiotic

Moxifloxacin Hydrochloride often turns up as a prescription for nasty infections. Doctors hand it out when milder antibiotics don’t work, and it acts fast against tough bacteria. Power like that doesn’t come without trade-offs. It’s easy to overlook those fine print warnings glued to the pill bottle, but moxifloxacin comes with real risks that can hurt more than help if ignored.

Heart Problems Aren’t Just Fine Print

Some folks, especially older adults or people taking certain heart medications, face a higher chance of rhythm troubles. Moxifloxacin can stretch out the QT interval—a fancy way of saying your heart might beat out of sync. That’s not some distant risk. It happened to someone in my family who had no clue about any heart issues until this antibiotic set off a series of dizzy spells and extra hospital visits. Always tell the doctor if you ever faint, notice strong racing heartbeats, or have a family history of heart rhythm problems.

Don’t Ignore Tendon Pain

Moxifloxacin sits in the fluoroquinolone class. Stories keep popping up of people tearing tendons or limping after use. The FDA even put a special boxed warning for this. If your job or hobby relies on healthy joints—picture anyone from a warehouse worker to a runner—think twice. I’ve seen weekend athletes push through mild ache thinking it’s nothing, only to end up with ruptured Achilles tendons. If you feel sudden joint or muscle pain, swelling, or weakness, drop the medication and call your doctor fast.

Nerve Side Effects Strike Without Warning

Peripheral neuropathy sounds clinical, but it feels like pins-and-needles, numbness, or sharp pain running through your arms and legs. This isn’t some rare event. The damage can last long after the infection clears up. I met someone who can’t button shirts or open jars anymore—simple tasks, all because of nerve pain that started after this medication. If you get new sensations that scare you, don’t just ride them out.

Complications in Mental Health and Glucose Control

Not enough people talk about the emotional side effects. Hallucinations, mood swings, agitation, or even confusion can pop up. For people with diabetes, the drug may throw off blood sugar. Some end up with dangerously low or high readings that force constant adjustments. Keep tabs using a glucose meter, and call someone you trust if your mood darkens.

Safe Use Starts With Honest Conversations

Doctors and pharmacists aren’t mind readers. Bring up every medication, supplement, over-the-counter pill, or existing health problem. Past allergic reactions and family health history matter. Sometimes, better alternatives exist, especially for minor infections or those with tough health backgrounds.

What You Can Do

Never cut your own medicine supply but never finish a course that makes you feel worse. Honest reporting of every side effect backs up better warnings for everyone. The FDA tracks these, and the more they hear, the safer medicines become for all. Ask about written information and possible symptoms to watch out for before starting any new prescription. Real stories and real harm drive those warning labels.

Takeaway

Moxifloxacin Hydrochloride helps many people, but it packs a punch. Your safety hangs on open communication, good questions, and attention to the way your own body feels during treatment. This is how people take back control, even when illness puts life on pause.

Can Moxifloxacin Hydrochloride interact with other medications?

The Heartbeat of Antibiotic Safety

Moxifloxacin hydrochloride stands as a heavy-hitter among antibiotics, knocking out stubborn bacterial infections when less potent drugs give up. But with that power comes risk, especially for folks juggling more than one prescription. Stepping into a pharmacy, you see walls stacked with pills, each one with its own story—and sometimes those stories clash.

Interactions That Matter

Mixing moxifloxacin with the wrong medications can stir up real trouble. Take the heart, for instance. Moxifloxacin carries a warning about prolonging the QT interval—the segment on an EKG that measures the heart’s electrical recovery time. Folks might not pay attention until they realize drugs like amiodarone, sotalol, or even some antidepressants crank up that risk. The combination can lead to a jolt of arrhythmia or even a fatal episode.

Doctors often cross-check moxifloxacin prescriptions with older folks’ medication lists. Not only is heart health a bigger issue in older adults, but some medicines used for common conditions slip under the radar. Diuretics—often called water pills—and steroids drop potassium levels, which already adds fuel to the fire for dangerous rhythms. Stacking all those risk factors teeters close to disaster.

The Sneaky Impact of Antacids and Minerals

Stomach medicines can also act as spoilers. Pop an antacid or a mineral supplement loaded with magnesium, aluminum, iron, or zinc, and the body loses its grip on moxifloxacin absorption. Less antibiotic in the blood means the infection keeps festering, and suddenly the promise of a cure gets dashed. Many patients don’t consider that their chewable heartburn relief from the grocery shelf can quietly sabotage their antibiotic. Doctors urge leaving a two-hour gap between taking these and swallowing moxifloxacin.

Blood Sugar Surprises and Other Concerns

Diabetics face their own set of potholes. Moxifloxacin, like other quinolones, tinkers with blood sugar—sometimes leading to wild swings. Throw in a sulfonylurea or insulin, and sugar levels may drop or spike with little warning. Add to that common painkillers, NSAIDs like ibuprofen, and there’s a rare but real risk of seizures, especially in vulnerable patients.

In the emergency room, medical staff scramble to keep a complete list of every pill, drop, or herbal an older patient takes. Even herbal teas or over-the-counter vitamins can trip up a careful plan if they aren’t mentioned.

Real Solutions Start with Conversation

The best defense isn’t digital charts or pop-up warnings—it’s talking to a pharmacist or doctor before combining medicines. Most professionals have seen more drug mix-ups than we can imagine and know how to steer clear of trouble. Having a single pharmacy fill all prescriptions sharpens the safety net, making big mistakes less likely.

Taking antibiotics isn’t just about knocking out an infection. It’s about weighing risks, understanding side effects, and appreciating how every medicine interacts with the rest. Keeping those lines of communication open saves lives, plain and simple. For those living with complex medication routines, a clear record and honest conversation often make all the difference.

Moxifloxacin Hydrochloride
Names
Preferred IUPAC name 1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-quinoline-3-carboxylic acid hydrochloride
Other names Avelox
Vigamox
Moxeza
Moxifloxacino
Moxifloxacine
Moxifloxacina
Pronunciation /ˌmɒk.sɪˈflɒk.sə.sɪn haɪˌdrɒ.kləˈraɪd/
Identifiers
CAS Number 186826-86-8
3D model (JSmol) `3D model (JSmol)` string for **Moxifloxacin Hydrochloride**: ``` C1CC(CNC1C2=CN=C3C(=C2)C(=O)C4=C(C(=O)C(=CN4CC5=CC=CC=C5F)F)N3)O.Cl ``` This is the SMILES string representing the 3D structure for use in molecular viewers like JSmol.
Beilstein Reference 1432924
ChEBI CHEBI:63699
ChEMBL CHEMBL521
ChemSpider 66859
DrugBank DB00218
ECHA InfoCard 03b9786a-eacd-43df-b3c6-4cd93613d8f3
EC Number 620-703-9
Gmelin Reference Gmelin Reference: "840358
KEGG D01966
MeSH D03.633.100.221.173.525.600
PubChem CID 152946
RTECS number QSJ6954410
UNII JR7VXT8C5M
UN number UN3249
CompTox Dashboard (EPA) DTXSID5036046
Properties
Chemical formula C21H24FN3O4·HCl
Molar mass 401.9 g/mol
Appearance Light yellow crystalline powder
Odor Odorless
Density 1.6 g/cm³
Solubility in water Soluble in water
log P 1.6
Acidity (pKa) 6.4
Basicity (pKb) 9.4
Magnetic susceptibility (χ) `-32×10⁻⁶ cm³/mol`
Refractive index (nD) 1.683
Viscosity Not less than 85% and not more than 115% of the Labeled amount of C21H24FN3O4·HCl.
Dipole moment 2.34 D
Thermochemistry
Std molar entropy (S⦵298) 385.8 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -1129.7 kJ/mol
Pharmacology
ATC code J01MA14
Hazards
Main hazards May cause allergic skin reaction, serious eye damage, respiratory irritation
GHS labelling GHS07, GHS08
Pictograms Rx only, oral use, keep out of reach of children, store below 30°C, protect from light
Signal word Warning
Hazard statements Harmful if swallowed. Causes serious eye irritation. May cause an allergic skin reaction.
Precautionary statements Store below 30°C. Protect from light & moisture. Keep out of reach of children.
Flash point > 272.1 °C
Lethal dose or concentration > LD50 Oral Rat: 3166 mg/kg
LD50 (median dose) > 972 mg/kg (Rat, oral)
NIOSH RS014
PEL (Permissible) Not Established
REL (Recommended) 400 mg once daily
IDLH (Immediate danger) Not established
Related compounds
Related compounds Ciprofloxacin
Levofloxacin
Ofloxacin
Gatifloxacin
Norfloxacin
Enoxacin
Gemifloxacin
Lomefloxacin
Fleroxacin
Trovafloxacin