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Product Name: Moxidectin
Synonyms: Cydectin, Quest, Moxidectin A1
Chemical Family: Macrocyclic lactone antiparasitic
Chemical Formula: C37H53NO8
Molecular Weight: 639.8 g/mol
CAS Number: 113507-06-5
Manufacturer: [Company-specific name]
Recommended Use: Veterinary antiparasitic
Restrictions on Use: Not intended for human consumption
Emergency Contact: [Refer to local guidelines or Safety Officer contact]
GHS Classification: Acute oral toxicity Category 3, Skin irritation Category 2, Eye irritation Category 2, Acute aquatic toxicity Category 1
Hazard Pictograms: Skull and crossbones, exclamation mark, environment
Signal Word: Danger
Hazard Statements: Toxic if swallowed, causes skin and eye irritation, very toxic to aquatic life
Precautionary Statements: Do not eat, drink or smoke when using; avoid release to the environment; wash hands thoroughly after handling; use personal protective equipment as required
Primary Routes of Exposure: Inhalation, ingestion, skin/eye contact
Potential Health Effects: Abdominal pain, nausea, skin redness, respiratory irritation, central nervous system symptoms with overdose
Chemical Name: Moxidectin
Concentration: 95%–100% (active pharmaceutical ingredient)
Impurities: Not typically present above the reporting threshold
Other Ingredients: Stabilizers, solvent residues (as trace amounts)
CAS Registry Number: 113507-06-5
General Advice: Move subject from exposure area to ventilation; keep at rest.
Ingestion: Rinse mouth with water. Seek medical attention immediately. Do not induce vomiting unless instructed by medical personnel.
Inhalation: Remove to fresh air. Monitor for signs of respiratory distress. Seek immediate medical attention if symptoms develop.
Skin Contact: Wash skin thoroughly with soap and water for at least 15–20 minutes. Remove contaminated clothing.
Eye Contact: Rinse opened eyes under running water for several minutes. Remove contact lenses. Seek quality medical help if irritation persists.
Symptoms to Watch: Drowsiness, nausea, blurred vision, allergic reactions, difficulty breathing.
Notes for Physician: Provide supportive care; treat symptomatically.
Suitable Extinguishing Media: Foam, carbon dioxide, dry chemical, water spray
Unsuitable Extinguishing Media: High-power water jet (risk of spreading)
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides, smoke
Protective Equipment and Precautions: Wear full protective gear and self-contained breathing apparatus
Flammable Properties: Not highly flammable but may burn under extreme conditions
Firefighting Instructions: Keep containers cool with water. Prevent pollutant firefighting runoff from entering drains or surface waters.
Explosion Hazard: Fine dust may form explosive mixtures with air.
Spill Response: Evacuate area, ventilate. Wear gloves, protective mask, protective eyewear.
Personal Precautions: Limit inhalation and skin contact. Avoid clouds of dust.
Environmental Precautions: Prevent entry into watercourses, drains, and soil.
Methods for Clean-Up: Sweep up without raising dust, contain material, and transfer to labeled waste container. Wash residues with copious water. Dispose per environmental regulations.
Small Spills: Dampen, scoop up, wipe residue.
Large Spills: Dike far ahead of liquid spill for collection and disposal.
Decontamination: Wash area thoroughly after spill removal.
Safe Handling Practices: Avoid contact with eyes, skin, and clothing. Do not breathe dust or vapor. Use only in well-ventilated areas. Do not eat, drink, or smoke while handling the substance.
Hygiene Measures: Wash thoroughly after handling.
Storage Conditions: Store in tightly closed container; keep in a cool, dry, well-ventilated place.
Keep Away From: Direct sunlight, strong acids, oxidizing agents.
Incompatible Materials: Acids, bases, strong oxidizers.
Shelf Life: Refer to manufacturer’s stated expiration for product integrity.
Packaging Materials: Use compatible, chemical-resistant containers.
Special Provisions: Lock storage area; restrict access only to authorized personnel.
Occupational Exposure Limits: No specific OSHA, NIOSH or ACGIH limits assigned; minimize dust generation.
Engineering Controls: Use local exhaust or general ventilation to control airborne exposure.
Respiratory Protection: Approved respirator if dust, vapor, or fumes exceed recommended limits.
Eye/Face Protection: Chemical safety goggles or face shield.
Skin/Body Protection: Wear lab coat, coveralls, chemical-resistant gloves (nitrile or neoprene recommended).
Hand Protection: Impermeable gloves selected for chemical compatibility.
Other Protective Equipment: Use safety shower and eye wash station in work area.
Work Practice Controls: Avoid walking through spill area. Do not touch contaminated surfaces with bare skin.
Appearance: Light yellow to white solid, crystalline powder
Odor: Odorless or slight organic odor
Odor Threshold: Not established
pH: Not applicable (insoluble in water)
Solubility: Practically insoluble in water, soluble in organic solvents like acetone, dimethylsulfoxide
Melting Point: 141–146°C
Boiling Point: Decomposes before boiling
Vapor Pressure: Negligible at room temperature
Vapor Density: Not available
Specific Gravity: Approx. 1.2–1.3 (estimated)
Partition Coefficient (log P): 5.6
Flash Point: Not flammable under typical conditions
Auto-Ignition Temperature: Not determined
Viscosity: Not applicable
Evaporation Rate: Not applicable
Explosive Properties: Fine dust may create explosion risk in air.
Oxidizing Properties: Not classified as an oxidizer.
Chemical Stability: Stable under normal conditions of handling and storage
Reactivity: No dangerous reactions known under recommended conditions
Hazardous Reactions: Avoid mixing with strong acids, bases, or oxidizing agents
Decomposition Products: May emit toxic fumes, including nitrogen oxides, carbon monoxide, and carbon dioxide, during thermal decomposition
Conditions to Avoid: Excess heat, direct sun, moisture. Strong oxidizers or acids can cause rapid degradation.
Polymerization: Will not occur under standard conditions.
Acute Toxicity: Oral LD50 (rat): 61 mg/kg; Dermal LD50 (rat): >2,000 mg/kg; Inhalation: data not determined
Symptoms of Exposure: Headache, dizziness, nausea, ataxia, vomiting, possible convulsions at high doses
Irritation: Causes skin and serious eye irritation; prolonged or repeated contact may intensify effects
Sensitization: Possible skin sensitizer; rare cases of allergic reaction reported
Chronic Effects: Not classified as carcinogen, mutagen or reproductive toxicant in the current evidence base
Target Organs: Nervous system may be affected in large exposures
Medical Conditions Aggravated: Individuals with pre-existing neurological conditions should minimize exposure.
Other Data: No known human epidemiological studies published; data primarily from animal models
Ecotoxicity: Extremely toxic to aquatic organisms; high risk to invertebrates and fish at trace levels
Aquatic Toxicity: LC50 (Fish, 96hr): 0.0032 mg/L; EC50 (Daphnia, 48hr): 0.00034 mg/L
Persistence/Degradability: Not readily biodegradable in soil or water; environmental persistence expected
Bioaccumulation: High potential for bioaccumulation, especially in aquatic systems (log Kow >5)
Soil Mobility: Moderate to low mobility in soil; binds strongly to organic matter
Other Adverse Effects: Decreases populations of non-target insects; impacts soil microfauna and dung-recycling insects
Notes: Avoid contamination of local waterways; long-term environmental effects possible
Product Disposal: Hand off expired or unwanted material to licensed hazardous waste contractors; incinerate under controlled conditions
Container Disposal: Triple rinse empty containers; recycle or puncture and bury in approved landfill as allowed by regulations
Disposal Restrictions: Do not discharge into surface water, soil, or storm drains.
Precautions: Wear protective gear when disposing of product or residue.
Local Regulations: Follow country, state, and local laws governing chemical disposal.
Special Instructions: Consult environmental officer before large-scale disposal or remediation.
UN Number: 3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (contains moxidectin)
Transport Hazard Class: 9
Packing Group: III
Marine Pollutant: Yes
Special Transport Provisions: Use original, sealed containers; label per hazardous materials regulations
Emergency Response Guide Number: 171
International Air Transport (IATA): Not regulated as hazardous if shipped in small quantities but always check carrier’s instructions
Transportation Precautions: Secure loads, maintain separation from foods and feedstuffs, avoid temperature extremes.
TSCA Status: Not listed
RCRA Status: Not a listed hazardous waste, but state/local regulations may apply
OSHA Status: Not specifically regulated by OSHA
SARA Title III: Not subject to reporting under Sections 302, 304, 313
California Proposition 65: Not listed
EPA Registration: Registered under FIFRA for use as a veterinary antiparasitic
European Regulations: Listed in EINECS/ELINCS; classified as toxic to environment (Dangerous for the Environment, N)
WHMIS (Canada): D2B (Toxic Material Causing Other Toxic Effects)
Other Regulations: Users should check with local, federal, and regional agencies for updated requirements.
