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Product Name: Methylphenidate Acid
Chemical Formula: C14H19NO4
Synonyms: Ritalinic acid; Hydrochloride Salt of Ritalinic acid
Recommended Use: Research, pharmaceutical intermediate
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CAS Number: 19395-41-6
Hazard Classification: Irritant to eyes, skin; potentially harmful by inhalation
Signal Word: Warning
Hazard Statements: Causes eye and skin irritation, toxic if ingested or inhaled, may cause respiratory tract irritation
Precautionary Statements: Prevent contact with skin and eyes, wash hands thoroughly after handling, use only in a well-ventilated place, avoid generation of dusts or aerosols
Pictograms: Exclamation mark
Routes of Exposure: Eye, skin, inhalation, ingestion
Target Organs: Nervous system, respiratory system, skin, eyes
Chemical Name: Methylphenidate Acid
CAS Number: 19395-41-6
Concentration: ≥98% (by weight)
Impurities and Additives: Minimal, typically below 2% (by weight)
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, seek medical attention if irritation persists
Skin Contact: Immediately wash with plenty of soap and water, remove contaminated clothing, get medical attention if symptoms continue
Inhalation: Remove person to fresh air away from exposure, keep person comfortable for breathing, if symptoms develop, get medical advice
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting, seek prompt medical help
Most Significant Symptoms: Irritation to mucous membranes, headache, dizziness, nausea
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet in confined areas due to splatter risk
Special Hazards: May give off toxic fumes such as nitrogen oxides, carbon monoxide during fire
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear
Instructions: Move containers from fire area if safe, avoid inhaling combustion products, control run-off to prevent entry into drains and waterways
Personal Precautions: Use personal protective equipment, avoid breathing dust, ensure adequate ventilation
Environmental Precautions: Prevent material from entering drains and surface water, dike spillage if possible
Methods for Clean-Up: Sweep up and place in a suitable container for disposal, wipe residual amounts using a damp cloth with detergent, ventilate area, wash affected area after collection is complete
Disposal of Contaminated Material: Dispose as chemical waste following local regulations
Handling: Use appropriate personal protection, avoid generation of dust, avoid inhaling any dust or fumes, wash hands after use, do not eat or drink during handling
Storage: Store in tightly closed containers, keep in a dry, well-ventilated place, store at room temperature (15–25°C), protect from moisture, segregate from oxidizing agents and strong acids
Specific End Use(s): Laboratory chemical, intermediate for synthesis
Control Parameters: No established occupational exposure limits, monitor air levels if dust formation is likely
Engineering Controls: Work in fume hood or use adequate exhaust ventilation
Personal Protective Equipment:
Gloves (nitrile or appropriate chemical-resistant), lab coat or protective clothing, safety glasses with side-shields or chemical goggles
Respiratory Protection: Use dust mask or respirator if dust or aerosol formation occurs
Hygiene Measures: Wash hands and face after handling, remove contaminated clothing and wash before reuse
Appearance: White to off-white crystalline powder
Odor: Odorless or slight characteristic odor
pH: Neutral to slightly acidic (5-7, aqueous solution)
Melting Point: Above 150°C
Boiling Point: Not available (decomposes before boiling)
Flash Point: Non-flammable
Solubility: Soluble in water, alcohol
Vapor Pressure: Negligible at room temperature
Relative Density: Approximately 1.2 g/cm³
Other Data: Stable under recommended handling, sensitive to strong oxidizers
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: No dangerous reactions known under normal conditions
Conditions to Avoid: Moisture, extreme heat, incompatible chemicals
Incompatible Materials: Strong acids, strong oxidizing agents, alkali metals
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides
Hazardous Polymerization: Will not occur under normal conditions
Acute Toxicity: Data limited; similar compounds have low to moderate acute toxicity
Routes of Exposure: May irritate eyes, skin, and respiratory tract, harmful if ingested in quantity
Symptoms: Nausea, vomiting, headache, dizziness, sensitization potential
Chronic Effects: No data on repeated dose toxicity, presumed low risk at low exposure
Carcinogenicity: Not classified as carcinogenic by IARC, OSHA, or NTP
Mutagenicity/Teratogenicity: No known risk based on available data
Further Information: Observe proper industrial hygiene and avoid unnecessary exposure
Ecotoxicity: Data on specific compound limited, related compounds suggest low aquatic toxicity
Biodegradability: Expected to degrade slowly in environment
Mobility: May move through soil, especially if spilled
Bioaccumulation Potential: Low based on predicted partitioning behavior
Other Environmental Risks: Avoid release to waterways to help protect aquatic life
Waste Disposal Methods: Dispose of as chemical waste, follow all local, regional, national, and international regulations
Container Disposal: Triple rinse, puncture, and send to licensed chemical disposal facility
Contaminated Packaging: Treat as hazardous waste, dispose per regulations
Sewage Disposal: Do not discharge to drains or rivers, contain and collect spills whenever possible
UN Number: Not classified as dangerous for transport
Transport Hazard Class: Not regulated
Packing Group: Not assigned
Label Shipping Name: Laboratory chemical or research compound
Special Precautions: Use sealed containers, avoid direct sunlight and high temperatures during transit
Transport in Bulk: Not suitable for bulk transport
Inventory Status: Listed or exempt on national chemical inventories
Federal Regulations: Not specifically regulated by US EPA or OSHA as a hazardous substance
SARA Title III: Not listed as a hazardous chemical
California Proposition 65: Not listed
REACH Status (EU): Research use, not registered for commercial applications
Additional Information: Users must comply with any updates or amendments to chemical or workplace safety laws wherever handled or used
