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Methylcobalamin belongs to the cobalamin class, a group of compounds recognized for their essential role in human health since the discovery of vitamin B12 deficiency as a cause of pernicious anemia in the early 20th century. Early research saw scientists wrestling with the mystery of an “anti-pernicious anemia factor” in liver extracts. Through lengthy and methodical work involving Nobel winners like Dorothy Hodgkin and George Whipple, vitamin B12’s structure and different forms were finally identified. Among these, methylcobalamin emerged as a naturally active form in the body, found in food sources like fish, meat, milk and eggs, as well as produced by certain bacteria. My own clinical experience and research readings have shown a slow shift in medicine: injectable cyanocobalamin—synthetic and easy to make—set the standard for decades. Once labs established methylcobalamin’s distinct biochemical roles, especially in nerve health, interest picked up in using this specific compound for targeted therapies, rather than defaulting to its synthetic cousins.
Methylcobalamin comes as a red crystalline powder, a trait shared among many cobalamin forms due to the cobalt atom at its core. You see it available in bulk for supplement manufacturers, in tablets and capsules for over-the-counter vitamins, and in injectable forms for medical use. This product forms the backbone of many B12 supplementation programs. It’s found in pharmacy vitrines and health food shops alike, sometimes used under dose guidance by physicians for people dealing with nutritional gaps, aging, or nerve problems. Companies sell it by various trade names and under generic labeling, from mainstream nutraceutical brands to clinical-use pharmaceutical vials.
Methylcobalamin stands out in the lab with its bright red crystals. It dissolves in water but breaks down when exposed to light and high temperatures. Its structure centers around a corrin ring, a cobalt atom, and a methyl group attached as its primary ligand—a setup crucial for how cells recognize and use the vitamin. Its molecular formula clocks in at C63H91CoN13O14P, yielding a hefty molecular mass and making it one of the most complex vitamins humans use. This structural complexity makes manufacturing challenging but gives it a crucial advantage in neurological health because the methyl group is ready for biological action without conversion, the way cyanocobalamin or hydroxocobalamin require. I remember in my lab days, storage always mattered: keep the bottles dark, cool, and tightly sealed, or the color fades and activity drops.
A look at supplement facts panels will show that methylcobalamin often gets measured in micrograms or milligrams. Packaging lists content per tablet or vial, purity percentages, and expiration dates, reflecting stability research conducted under various storage conditions. Reputable manufacturers include certificates of analysis showing testing for heavy metals, microbial contamination, and specific vitamin content using HPLC or spectrophotometry. A tablet labeled “methylcobalamin 1 mg” typically fulfills daily requirements with a massive margin, since the RDA for vitamin B12 hovers around 2-3 micrograms for adults. Labels also mention “methyl B12” as a synonym, and list excipients added for tablet form or carriers in liquids. Serious supplement users check these documents to avoid undisclosed additives or allergens and to verify the product delivers real methylcobalamin rather than a low-grade generic form.
Manufacturing methylcobalamin demands technical skill and careful process control. The chemical builds up via biosynthetic fermentation, often using genetically engineered microbes—usually Propionibacterium or Pseudomonas strains—fed nutrients like cobalt salts. Once colonies multiply and generate crude vitamin B12, chemical modification swaps out the original cobalt ligand for a methyl group, usually through methylation reactions under strict conditions. The compound gets isolated, crystallized, and repeatedly washed to remove fermentation residues. Picking the right growth media and purification method strongly affects yield and contaminants. Years back, I witnessed a production facility walk-through where every section from fermentation bioreactor to high-pressure liquid chromatography column had teams monitoring the process, proof of how much effort goes into a single batch of this bright vitamin.
Methylcobalamin differs from cyanocobalamin and adenosylcobalamin mostly through the functional group attached to the cobalt core. Chemists can swap groups through nucleophilic substitution, using methyl halides to latch a methyl group onto reduced cobalamin intermediates. Acidic or oxidative settings break the methyl group off, reverting the compound back to a base cobalamin structure. These reactions also open doors for labeling vitamin B12 derivatives for research, tracing metabolic pathways in animal and cell studies. I’ve seen research labs tune these modifications for radio-labeling, which proves essential in tracking the vitamin’s fate in the body or in mapping out neurological repair processes, especially for demyelinating diseases where methyl group transfer plays a key role.
A shopper or prescriber bumps into plenty of alternative names for methylcobalamin: “Mecobalamin,” “Methyl B12,” “Coenzyme B12,” “Cobalamin (methyl),” among others. Each name reflects a slice of chemistry or a marketing angle. Some brands adopt codes or catalog numbers, catering to labs buying analytical-grade samples. Japanese and Indian pharmaceutical firms label it as Mecobalamin on prescription sheets, thanks to local regulatory listings, while US labels almost always feature “methylcobalamin” prominently. Blanket designations like “active B12” or “coenzyme B12” crop up, though technically, adenosylcobalamin competes for the “coenzyme” title in biochemistry textbooks.
Handling methylcobalamin in manufacturing plants or medical settings follows strict playbooks: workers wear gloves to avoid skin contact, maintain clean rooms to keep out bacteria and human hair, and monitor air temperature and humidity. Manufacturing lines include steps for in-process batch testing—checking for purity, checking the pH of solutions, and confirming sterility for injectable versions. These steps help catch contamination risks, like heavy metals from fermentation tanks or pyrogens from bacterial breakdown. The supplement and pharmaceutical industry borrows many procedures from GMP (Good Manufacturing Practice), FDA guidelines, and ISO quality systems—approaches that reduce recalls, product variability, and consumer risk. The Vitamin B12 complex sits on the low end for toxicity, but real-world reports show allergic reactions or rare sensitivities in high-dose users. Medical teams remain alert to reactions, particularly in injection clinics, always keeping epinephrine at hand in case of rare but serious allergies.
Doctors turn to methylcobalamin for classic B12 deficiency, especially in patients with impaired absorption—elderly folks, people with gastric surgery, vegetarians, and folks on long-term heartburn medicines. It plays a recognized role in treating neuropathies, from diabetic nerve pain to “pins and needles” cases seen in chemotherapy survivors. In Japan and parts of Europe, the compound enjoys wide prescription for nerve repair and general vitality, based on clinical results over several years. Supplement makers push it for cognitive support, energy boost, and healthy mood claims—even though some of those benefits go beyond current science. From my own dives into neurology research, studies suggest methylcobalamin can accelerate nerve regeneration after injury, and some clinical reports link daily supplements with improved sleep cycles in people with circadian rhythm disorders. Its ready-to-use methyl group speeds up processes in methylation pathways, a big selling point for folks with certain genetic variations (like MTHFR mutations), who don’t convert cyanocobalamin efficiently.
University labs and pharmaceutical companies keep chasing new angles for methylcobalamin. The vitamin draws interest in neurology, looking past anemia to how it helps with axonal repair and healthy myelin production. There’s an uptick in papers on autism, dementia, and amyotrophic lateral sclerosis (ALS), probing whether extra methylcobalamin tweaks the pace of neurological decline or symptom relief. Teams test modified forms or delivery systems—slow-release tablets, nasal sprays, sublingual lozenges—to drive better absorption especially for those with gut problems. Tech advances in recombinant DNA and fermentation processes drive down costs and improve purity, helping get the right dose in developing countries where deficiency remains a hidden threat. At industry events, researchers swap data on actionable health outcomes, but real breakthroughs hinge on how well future studies nail down cause and effect in patient groups.
Published science paints methylcobalamin as extremely safe, with no established upper intake limit for normal adults. Clinical trials in humans often dose up to several milligrams per day without major incident. Animal tests stretching the dosing far above typical intake show a high threshold before adverse effects surface. Still, isolated cases of acne-like rash, itchy skin, or trouble breathing have surfaced, especially with injectable forms. For patients with kidney failure, excess accumulation of inactive B12 forms has raised questions, though clear links to harm remain weak. Data from long-term supplement users show that, aside from rare allergic reactions, methylcobalamin carries far less risk than most medications or even certain other vitamins. Public health bodies, such as the NIH, recommend B12 checks for older adults or people with certain medical conditions, but they seldom sound alarm bells about methylcobalamin’s toxicity profile. Tighter research around special cases—a genetic inability to process methylcobalamin, or underlying blood disorders—could carve out exceptions, but for the average person, high-dose supplements look safer than a typical multivitamin containing fat-soluble vitamins at high doses.
Looking at global health trends, methylcobalamin stands on the edge of both opportunity and challenge. Life expectancy rises, and more people seek ways to preserve nerve health, boost energy, or compensate for age-related shifts in digestion. Veganism continues to spread, and B12 needs get more recognition in plant-based communities. Tech-forward production methods—bioreactors with tailored bacteria, cleaner purification processes, better quality assurance—promise to lower cost and broaden access. The medical field watches for big, long-term trials to answer questions about preventing cognitive decline or reducing neuropathy risk in at-risk groups. Pharmaceutical engineers develop new forms of delivery, aiming to suit picky eaters, children, or patients with taste sensitivities. At international conferences and healthcare meetings, experts push for clear labeling and unbiased clinical data, so consumers and prescribers get real answers, not just marketing spin. As more researchers test the boundaries of what methylcobalamin can do beyond traditional deficiency treatment, society’s challenge will be sorting the hype from the science, ensuring fair access, and keeping safety standards high as global demand accelerates.
Methylcobalamin is a form of vitamin B12 that comes up often in pharmacies and supplement shops. Some folks know it as the “active” B12, and it plays a serious role in the body. Every cell, from the tiniest in your toes to those running your brain, depends on B12 for energy production, DNA work, and keeping nerves talking to each other. I’ve met people who felt foggy, weak, and even numb in their hands and feet and later found out something as basic as B12 deficiency sat at the root of the problem.
People sometimes shrug at vitamins, but B12 gets tricky, especially for vegetarians, vegans, or older adults. Most B12 in diets comes from animal sources, so skipping those foods can mean real trouble later on. Studies published by Harvard and Mayo Clinic warn that about 15 percent of people over 60 show signs of B12 deficiency—sometimes from gut issues, not food choices. Taking a supplement like methylcobalamin bypasses some of these problems because the body can use it right away.
Low B12 can slow you down more than you might expect. I remember chatting with a friend, an athlete pushing through fatigue and sluggish legs, only to find out a simple B12 test flagged his low levels. Methylcobalamin puts itself to work quickly and sometimes brings folks back from that drained, foggy feeling. Tingling fingers, pale skin, mood swings, and memory slips sometimes connect back to a shortage of B12. Unchecked, it can get serious—think nerve damage and megaloblastic anemia, which leaves red blood cells large and less useful.
Walk through any supplement aisle and you’ll spot bottles labeled cyanocobalamin and methylcobalamin. Both support B12 needs, but methylcobalamin skips an extra conversion step in the liver. For those with certain gene variations—roughly 10 to 20 percent of the population—this skipping step matters. Methylcobalamin directly helps nerves and the brain, making it a better pick for folks dealing with neurological symptoms tied to low B12.
Doctors and nutritionists often steer patients to methylcobalamin for stubborn cases: peripheral neuropathy, diabetic nerve pain, or after stomach surgery that blocked B12 absorption. People with multiple sclerosis sometimes use it for nerve support. Folks on long-term metformin or acid blockers reach for it because those meds can block B12 uptake. Past a certain age, the stomach gets less efficient at grabbing B12 from food, so oral supplements or even injections become common. My own parents started using it once low B12 popped up on routine bloodwork.
Better awareness marks a good start. Busy doctors can miss subtle signs because symptoms look like aging. Routine blood panels, especially for high-risk groups, catch issues early. Methylcobalamin comes in many forms: pills, dissolvable tablets, and injectables. Clear guidance from doctors and pharmacists makes a huge difference, helping people avoid guesswork. Eating a mix of B12-rich foods, checking medications, and picking the right brand with proper dosing can steer people away from trouble. Knowledge truly puts power back in people’s hands, and sometimes one simple supplement changes the whole picture.
Methylcobalamin lives as a form of vitamin B12, something our bodies can’t make. Living with a B12 deficiency feels like moving through mud—low energy, tingling in your hands, and sometimes even memory slips. Doctors order this supplement mainly for people struggling to get enough B12, such as vegans, vegetarians, older adults, and folks with certain stomach and gut problems. In my own family, switching to a vegetarian diet forced us to pay closer attention to things like B12, since plant foods don’t carry this nutrient in amounts we need.
Most people take methylcobalamin as a pill, though you’ll find it in lozenges, injections, sprays, or even under-the-tongue dissolving tablets. Each method gets the nutrient to your bloodstream with different efficiency. Pills go through your stomach and gut before entering your blood, sometimes losing potency if you don’t absorb nutrients well. Injections or sublingual forms skip that entire first step, hitting the bloodstream fast—helpful for those who don’t digest vitamin B12 easily due to age, stomach surgeries, or certain medications.
Your body uses vitamin B12 in tiny amounts, but low storage can lead to nerve problems and anemia. Most adults need just 2.4 micrograms per day, and many supplements offer way more than that—sometimes thousands of micrograms. A healthy person with no risk factors can rely on their diet, or a standard multivitamin, to meet their needs. People with real deficiencies or those who’ve been prescribed high-dose methylcobalamin might get much larger doses, up to 1,000 micrograms daily under medical supervision. Some older adults and people with absorption issues require regular injections instead of oral forms. General rules rarely work for every person — lab tests and a doctor’s guidance give the best answer.
Methylcobalamin carries a strong track record for safety. I have taken it myself for fatigue, and besides neon yellow pee after a big dose, nothing unusual happened. Very high doses rarely bring mild upset stomach or headaches, and allergic reactions almost never show up. The body stores extra B12 in the liver or gets rid of what it doesn’t use. I’ve never met anyone who overdosed on B12 from supplements, though taking too many vitamins can burn a hole in your wallet or make your pee very expensive. Still, with any new pill, it pays to watch your body for unexpected reactions.
Doctors, registered dietitians, and pharmacists have strong training when it comes to supplements like methylcobalamin. Online forums and social media spit out dozens of dosing ideas, but that doesn’t mean they work for you. A quick appointment and a blood test settle doubts. Even drugstore B12 supplements work fine for most, if the brand follows quality standards and you take the amount recommended by your doctor. Nutrition isn’t one-size-fits-all—I learned that after years of watching relatives chase health fads. Reliable guidance and real bloodwork always give clearer answers than internet guesses.
The real key with methylcobalamin: personalize it. Pay attention to reason for taking it, know your risks, talk with your healthcare provider, and get regular tests if you’re at risk for deficiency. Eating a balanced diet, checking labels, and skipping mega-doses unless your provider says so keeps you covered. Consistent habits beat sporadic fixes. That kind of straightforward plan works for most people aiming to keep their B12 in the healthy zone without emptying their wallets or taking unnecessary risks.
Methylcobalamin pops up in health conversations, especially for people feeling wiped out, nerve issues, or those following a plant-based diet. It’s one of the forms of vitamin B12 that the body uses to keep nerves humming and red blood cells coming. For most folks, taking methylcobalamin is about getting energy back or patching up a deficiency.
Walk into a pharmacy, and you’ll find methylcobalamin in B12 supplements, injections, and all sorts of multivitamin blends. Why aren’t more people talking about side effects? It’s easy to assume “vitamin” always means “safe.” Life’s not that simple. My own interest in B12 ramped up after years on a vegetarian diet, when my hands started tingling. No one warned me about possible downsides of loading up on B12 supplements. It pays to look a little closer.
Most people can take methylcobalamin and barely notice anything. For those who react, side effects typically land on the mild side. Upset stomach, diarrhea, some itching, maybe a rash—these symptoms can happen if you take larger doses. Older studies show allergic reactions can sometimes follow injections, but tablets are less risky and rarely cause trouble. Some users have brought up dizziness or headache, though in my own experience and what doctors see in clinics, those cases stay rare.
Ignoring high doses and chugging supplements each day? That’s where risk grows. High levels might lead to an acne-like rash, especially in people with sensitive skin. There are even case reports with skin breakouts or rosacea flares. Some neurologists point out that anyone with severe vitamin B12 deficiency who starts treatment quickly might briefly feel anxiety or mood swings as nerves begin healing. This bumpy ride usually smooths out.
Not every body handles methylcobalamin the same way. People with kidney problems, for example, need to tread carefully. Since kidneys filter out B12, any supplement hanging around in the blood can add stress to already struggling organs. In my own family, a cousin with chronic kidney disease ended up with higher-than-normal B12 numbers without ever touching supplements, thanks to their kidney function. Add an extra dose, and things get messy fast.
Anyone dealing with allergies, especially if you’ve reacted to cobalt, needs a heads-up before starting methylcobalamin. Though rare, hypersensitivity can bring on hives, swelling, or even breathing trouble. These aren’t stories meant to scare, just a reminder that one-size-fits-all doesn’t exist in medicine.
Plenty of people grab supplements after a friend’s suggestion, a social media post, or a doctor’s quick comment. But not every tired body needs extra methylcobalamin. Simple blood work can settle whether you need B12 at all. Doctors sometimes run full panels rather than guessing. Once you know where you stand, it’s easier to choose the right dose—whether you’re taking daily pills or getting injections for a diagnosed deficiency.
Regular checkups help you sidestep accidental overload. Nobody benefits from loading up on vitamins without a reason. Pharmacists and clinicians provide guidance tuned to your age, gender, medical history, and diet. Nutrition has no shortcuts—good advice doesn’t come from the back of a supplement bottle.
Methylcobalamin provides a form of vitamin B12, which the body relies on for nerve health, red blood cell growth, and DNA production. Doctors often talk about vitamin B12 when helping pregnant women avoid certain deficiencies. Not getting enough B12 during pregnancy can carry risks for both mother and baby—think developmental problems or severe fatigue that sometimes leads to lasting nerve damage.
Pregnancy and breastfeeding turn normal nutrition on its head. Personal stories always stand out. I remember meeting a new mom who struggled with tiredness and tingling hands only to find out she wasn’t getting enough B12. After she began supplementing under medical advice, her symptoms faded. B12 isn’t a magic fix for every ache, but for women with low levels, it can change everything.
Plenty of adults meet their B12 needs by eating eggs, meat, dairy, or fortified cereals. Some folks turn to supplements, either by choice or out of necessity. Vegetarians, vegans, and women with certain stomach or digestive issues fall into this group more often. For pregnant or breastfeeding women, keeping B12 at the right level becomes much more important. That’s where questions about forms like methylcobalamin start to pop up.
Doctors have studied methylcobalamin and the standard cyanocobalamin for years. There isn’t evidence showing methylcobalamin causes harm to mothers or babies during pregnancy or breastfeeding. In fact, the body uses B12 to help a baby’s brain and nervous system get off to a strong start. Major health organizations such as the American College of Obstetricians and Gynecologists support B12 supplementation in mothers with documented low levels. The Centers for Disease Control and Prevention points out how pregnant women need 2.6 micrograms each day, and breastfeeding women need a bit more—2.8 micrograms.
Large doses rarely lead to side effects, since the body flushes out the excess. Research hasn’t linked normal doses of methylcobalamin to birth defects or problems for babies drinking breast milk. Still, not every woman's situation is the same. Women who have anemia, certain gastrointestinal conditions, or take medications that interfere with absorption need tailored advice.
While many turn to friends or online forums for answers, real peace of mind comes from honest conversations with doctors or registered dietitians. Routine blood tests can uncover a deficiency before symptoms ever show up. Health professionals might suggest B12 supplements in a prenatal vitamin or point out how to tweak meals to cover the gap. In situations where absorption is an issue, injections or higher oral doses of methylcobalamin sometimes get the job done.
Beware of self-diagnosing or chasing after the highest-dose supplement on the shelf. A doctor can weigh allergies, kidney conditions, or interactions with other medications—things the average person can easily miss.
Food sometimes falls short, especially for those who avoid animal products or stick to limited diets. Regular check-ins with healthcare providers, blood tests, and, if needed, well-chosen supplements all protect mother and baby. Sharing honest health history, asking questions about brands and doses, and keeping up with checkups build a safety net around families. Methylcobalamin supports those who actually need it, but only as one piece of the greater puzzle of maternal health.
Methylcobalamin, a form of vitamin B12, pops up everywhere from supplement aisles to doctor’s offices. It keeps nerves healthy and helps bodies produce red blood cells. Some people, especially those who’ve dealt with numbness or tingling in hands and feet, often hear about this vitamin. Doctors suggest it for folks with low B12 levels, often due to issues like dietary choices, chronic stomach problems, or old age. A lot of conversation about B12 revolves around cyanocobalamin, but methylcobalamin stands out for people who want the “active” B12—the type the body can use right away.
The right dosage depends on personal needs. I’ve seen people in clinics and at pharmacy counters, sometimes almost desperate, ask what dose to take after blood tests show their B12 is in the basement. For adults dealing with deficiency, doctors usually start with 1,000 micrograms, often daily for a stretch. After numbers get back to normal, many switch to that dose weekly or a couple times a month. For people taking methylcobalamin just to cover dietary gaps, 250 to 500 micrograms per day seems common and safe. Studies from the National Institutes of Health back up these numbers. More isn’t always better—mega-doses don’t seem to offer extra benefits and could just cost more money.
Kids with B12 deficiency need much smaller amounts. Doctors usually start with 50 to 100 micrograms depending on their age and how low their levels have dropped. Relying on advice from friends or what someone read online isn’t the best move, especially for kids. Blood work and guidance from someone who understands the numbers matter here.
One trap comes from the internet obsession with “biohacking.” Some folks, especially those who feel tired all the time, grab big bottles of B12 hoping to supercharge energy. For people without diagnosed deficiency or absorption issues, there’s no proof that high doses of methylcobalamin make a difference. For years now, research groups—including Harvard Medical School—have warned that most healthy adults get enough from food, assuming no health problems mess with absorption. Loading up on supplements doesn’t cure unexplained fatigue unless a real B12 shortage is in play.
Vegans, vegetarians, and people with digestive conditions get a different deal. Plants don’t give up B12, so people who skip animal products have to look to supplements or fortified foods. Older adults and those with certain medical issues can struggle to pull B12 from food, landing them in the “test and supplement” club. Instead of guessing, testing blood levels and working with a healthcare professional makes the most sense. Some people absorb B12 better through shots or sublingual tablets, so talking through options helps avoid wasted money or vitamin pills that do little good.
Trying to figure out the right dose takes more than reading the back of a bottle. Anyone thinking about methylcobalamin needs to talk with a doctor or registered dietitian, especially before upping doses on their own. Most reputable brands stick to doses that research supports for daily use. Avoid the temptation to buy “megadose” versions unless a real medical reason exists.
Absorption can get unpredictable. For those with certain gut problems, B12 by mouth may not work well. Sometimes injections or specific lozenges bypass the digestive tract. For persistent symptoms like numbness, memory slips, or unshakable tiredness, a conversation with a health professional beats guessing every time.
| Names | |
| Preferred IUPAC name | Cobamamide |
| Other names |
Vitamin B12 MeCbl Mecobalamin Methyl B12 |
| Pronunciation | /ˌmɛθɪlkoʊˈbæləˌmɪn/ |
| Identifiers | |
| CAS Number | 13422-55-4 |
| Beilstein Reference | 1849304 |
| ChEBI | CHEBI:64393 |
| ChEMBL | CHEMBL1206 |
| ChemSpider | 21737270 |
| DrugBank | DB00115 |
| ECHA InfoCard | 100.236.701 |
| EC Number | EC 4.1.1.41 |
| Gmelin Reference | 53568 |
| KEGG | Cobalamin |
| MeSH | D020805 |
| PubChem CID | 643914 |
| RTECS number | LC1400000 |
| UNII | 7QWM220FJH |
| UN number | UN3077 |
| CompTox Dashboard (EPA) | DTXSID2020679 |
| Properties | |
| Chemical formula | C63H91CoN13O14P |
| Molar mass | 1344.38 g/mol |
| Appearance | Red crystalline powder |
| Odor | Odorless |
| Density | 2.22 g/cm3 |
| Solubility in water | Slightly soluble |
| log P | -2.62 |
| Vapor pressure | Negligible. |
| Acidity (pKa) | Base pKa = 2.72 |
| Basicity (pKb) | 3.61 |
| Magnetic susceptibility (χ) | Paramagnetic |
| Refractive index (nD) | 1.610 |
| Dipole moment | 6.69 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 416.9 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -278.3 kJ/mol |
| Pharmacology | |
| ATC code | B03BA05 |
| Hazards | |
| Main hazards | No significant hazards. |
| GHS labelling | GHS07, GHS08 |
| Pictograms | health-hazard|exclamation-mark |
| Signal word | No signal word |
| Precautionary statements | Keep out of reach of children. If pregnant or breastfeeding, ask a health professional before use. Store in a cool, dry place. Protect from light. Do not use if seal is broken or missing. |
| NFPA 704 (fire diamond) | 1-1-0 |
| LD50 (median dose) | LD50 (rat, oral): >5000 mg/kg |
| PEL (Permissible) | PEL (Permissible Exposure Limit) for Methylcobalamin is not specifically established by OSHA or other major regulatory agencies. |
| REL (Recommended) | 1500 mcg |
| IDLH (Immediate danger) | Not listed |
| Related compounds | |
| Related compounds |
Cyanocobalamin Hydroxocobalamin Adenosylcobalamin Cobinamide |
