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Product Name: Menadione Sodium Bisulfite
Chemical Name: 2-Methyl-1,4-naphthoquinone sodium bisulfite complex
Product Use: Nutritional supplement, food additive, veterinary use, laboratory reagent
Manufacturer: Contact details available on commercial invoice and packaging
CAS Number: 130-37-0
Synonyms: Vitamin K3 sodium bisulfite, Menadione sodium bisulfite adduct
Emergency Contact: Refer to local poison control center or emergency services listed on package
GHS Classification: Eye irritation, Category 2A; Skin sensitization, Category 1; Specific target organ toxicity, single exposure Category 3
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, may cause an allergic skin reaction, may cause respiratory irritation
Precautionary statements: Avoid breathing dust; wash hands thoroughly after handling; use only outdoors or in well-ventilated area; wear protective gloves/eye protection; contain spillage
Label Pictograms: Exclamation mark
Routes of Exposure: Skin contact, inhalation, eye contact, ingestion
Potential Health Effects: Redness, tearing, itching of eyes; skin rash in sensitive individuals; throat and respiratory discomfort upon inhalation; nausea and abdominal pain if ingested
Chemical Name: 2-Methyl-1,4-naphthoquinone sodium bisulfite complex
CAS Number: 130-37-0
Concentration: 98–100%
Impurities: Water <2%, residual sodium sulfate <1%
Molecular formula: C11H8NaO5S
Molecular weight: 294.24 g/mol
Other Additives: None known to contribute to classification
Inhalation: Move affected individual to fresh air; administer oxygen if breathing is difficult; seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with soap and plenty of water for at least 15 minutes, consult physician if irritation develops
Eye Contact: Rinse eyes cautiously with water for at least 15 minutes holding eyelids apart, remove contact lenses if present, seek medical aid
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, seek immediate medical attention
Important symptoms/effects: Redness, eye pain, allergic reactions possible
Notes for physician: Treat symptomatically, monitor respiratory and allergic responses
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet on powder
Specific Hazards: Emits toxic fumes under fire conditions (sulfur oxides, carbon oxides, sodium oxides); dust may form explosive mixture with air
Protective Equipment: Full-face self-contained breathing apparatus, protective suit
Special Procedures: Prevent runoff from entering waterways, use water spray to cool exposed containers
Personal Precautions: Wear respirator, chemical-proof gloves, safety goggles, and protective clothing to avoid contact
Environmental Precautions: Prevent material from entering drains, surface or groundwater
Methods for Containment: Sweep up and collect spilled material without creating dust; place in suitable closed containers for disposal
Cleaning Methods: Vacuum with HEPA filter or wet brushing; avoid dry sweeping and generate as little dust as possible; ventilate area
Handling: Avoid breathing dust, direct contact with skin, eyes, and clothing; use local exhaust ventilation in handling areas; avoid generation of airborne dust
Safety Measures: Use only equipment rated for chemical powders; keep containers tightly closed when not in use; maintain good industrial hygiene
Storage Conditions: Store in a cool, dry, well-ventilated area away from sources of ignition and incompatible materials such as oxidizers and acids
Storage Container: Keep in original or approved tightly-sealed packaging
Storage Limits: Do not store large volumes without containment system
Incompatible Materials: Strong oxidizing agents, reducing agents, strong acids
Occupational Exposure Limits: No OSHA PEL or ACGIH TLV established; use workplace monitoring in high-dust settings
Engineering Controls: Local exhaust ventilation, process enclosure, safety showers, eye wash stations
PPE-Eye/Face: Chemical splash goggles or full-face shield
PPE-Skin: Resistant gloves (nitrile, latex), laboratory coat or coveralls
PPE-Respiratory: Approved particulate respirator/N95 mask, especially during powder handling
Environmental Controls: Prevent dust accumulation; use dust suppressants if needed
Appearance: Yellow to yellowish-brown crystalline powder
Odor: Faint, characteristic, non-pungent
Odor Threshold: Not determined
pH (1% solution): 6.5–7.5
Melting Point/Range: 225-230°C (decomposes)
Boiling Point/Range: Not applicable
Flash Point: Not flammable under standard conditions
Evaporation Rate: Not applicable
Flammability: May form combustible dust concentrations in air
Explosive Limits: Not established
Vapor Pressure: Negligible at room temperature
Vapor Density: Not relevant
Relative Density: 1.75–1.85 g/cm³
Solubility: Soluble in water
Partition Coefficient: Log Kow not available
Auto-ignition Temperature: Not determined
Decomposition Temperature: Above 220°C
Viscosity: Not applicable
Chemical Stability: Stable under ordinary conditions, hygroscopic when exposed to air
Reaction with Water: No hazardous reaction expected, dissolves easily
Reactivity: Reacts with strong oxidizing and reducing agents; generates heat and gases when mixed with acids or bases
Hazardous Polymerization: Will not occur
Decomposition Products: Sodium oxides, sulfur oxides, carbon oxides, toxic vapors
Conditions to Avoid: Temperature extremes, moisture, static discharges, incompatible chemicals
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: LD50 (oral, rat): ~500 mg/kg; LD50 (skin, rabbit): >2000 mg/kg
Skin Irritation: Moderate irritant to some individuals
Eye Irritation: Causes sustained irritation, possible corneal injury
Sensitization: May trigger allergic reactions with repeated skin contact
Carcinogenicity: No evidence in humans; IARC, NTP, OSHA do not classify as carcinogenic
Mutagenicity: Bacterial mutagenicity possible at high dosages
Reproductive Toxicity: No evidence of reproductive effects detected in standard studies
Chronic Effects: Repeated contact may result in persistent dermatitis or eczema for sensitive individuals
Ecotoxicity: Harmful to aquatic life at high concentrations (LC50 for fish: <10 mg/L/96hr)
Persistence/ Degradability: Moderately persistent in surface water conditions, slow degradation in neutral pH and low light
Bioaccumulative Potential: Expected low, log Kow not measured
Mobility in Soil: Moderately mobile, will infiltrate into porous soils in liquid form
Other Adverse Effects: Releases bisulfite ions which may contribute to oxygen depletion in water bodies
Disposal Methods: Dispose through licensed chemical waste contractors; solid waste landfill only if allowed by local regulation
Container Disposal: Triple rinse then offer containers for recycling or reconditioning if possible
Regulatory Considerations: Comply with all relevant local, regional, and national guidelines; do not dispose in drains or natural water courses
Precautions: Wear suitable protective equipment during handling and disposal
UN Number: Not regulated under most international transport codes (UN, IMDG, IATA)
Proper Shipping Name: Menadione sodium bisulfite or Vitamin K3, powder (non-hazardous)
Transport Hazard Class: Not classified
Packing Group: Not applicable
Environmental Hazards: No significant hazards for normal transport volumes
Special Transport Precautions: Avoid shipment with strong oxidizers and acids, keep containers tightly sealed
International Inventories: Listed in TSCA (USA), EINECS (EU); included in several local substance registries
OSHA Hazard Communication: Classified as hazardous per OSHA 29 CFR 1910.1200
SARA Title III: Not subject to reporting under Sections 302, 304, 311/312, 313
REACH Status (EU): Registered substance, refer to dossier for specific restrictions
California Proposition 65: Not listed
WHMIS Classification (Canada): D2B (toxic, eye/skin irritant)
Other national inventories: Complies with Japan ENCS, China IECSC, Korea ECL
Labeling requirements: Hazard pictograms, precautionary and hazard statements visible on packaging
