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Product Name: Latamoxef Sodium
Chemical Formula: C20H16N9NaO8S2
CAS Number: 86882-76-4
Synonyms: Moxalactam Sodium
Recommended Use: Antibiotic for clinical and research settings
Supplier Information: Manufacturer and supplier contact available on transport papers and label
Emergency Contact: Emergency numbers printed on label; local poison control centers provide 24-hour access
UN Number: 3249 (Drug, not otherwise specified)
Hazard Classification: Acute toxicity (oral, respiratory); sensitizer (skin, respiratory); potential carcinogen
GHS Label Elements: Exclamation mark, Health hazard pictogram
Signal Word: Warning
Hazard Statements: Harmful if swallowed or inhaled, may cause allergic reactions, eye and respiratory tract irritation
Symptoms of Exposure: Skin rash, eye irritation, difficulty breathing, nausea, headache, risk of anaphylactic reaction in sensitized individuals
Precautionary Statements: Avoid breathing dust; avoid skin, eye, or clothing contact; use in well-ventilated area; seek medical attention following exposure; wash hands thoroughly after handling
Chemical Name: Latamoxef Sodium
Concentration: 99% (pharmaceutical grade); remainder inert stabilizers
Impurities: Trace amounts of sodium salt byproducts, residual solvent below accepted thresholds
Molecular Weight: 590.5 g/mol
Physical Form: Fine crystalline powder
Inhalation: Remove to fresh air immediately; administer artificial respiration if breathing stops; keep airway clear; seek medical attention
Skin Contact: Remove contaminated clothing; wash affected area with soap and water for at least 15 minutes; seek medical intervention if irritation or sensitization occurs
Eye Contact: Flush with plenty of running water for 15 minutes, keeping eyelids open; consult a physician
Ingestion: Rinse mouth without swallowing; never induce vomiting unless directed by trained personnel; seek immediate medical care
Notes to Physician: Treat supportively; monitor for systemic allergic or anaphylactic response, especially with preexisting allergies
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide; avoid high-pressure jets
Specific Hazards Arising from Chemical: Hazardous compounds may include oxides of carbon, nitrogen, sulfur dioxide, and irritating fumes
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full protective suit, gloves, and eye protection
Fire/Explosion Risk: Product does not ignite easily; dust may form explosive mixtures with air under rare conditions
Special Precautions: Evacuate area, close doors to confine fire, avoid inhaling combusted material
Personal Precautions: Wear protective clothing, gloves, and respirator; prevent dust formation and dispersal
Environmental Precautions: Avoid discharge to drains, surface water, or soil; collect spillage; inform environmental authorities
Methods for Clean-Up: Sweep or vacuum spill using methods that minimize dust; place in suitable container for disposal; decontaminate area with detergent and water
Other Precautions: Ventilate area; restrict access until cleanup is complete
Safe Handling Advice: Minimize dust generation; avoid direct contact; use designated work practices for cytotoxic or antibiotic powders; employ containment devices
Storage Conditions: Store at 2–8°C (Refrigerated); keep tightly closed in original container; protect from moisture, light, and incompatible materials
Incompatibilities: Avoid strong oxidizers, reducing agents, acids, alkalis
Hygiene Practices: No eating, drinking, or smoking in handling area; wash hands thoroughly before breaks and after use
Technical Measures: Only trained personnel in designated laboratory or pharmacy facilities
Occupational Exposure Limits: Not formally established for active ingredient; recommended airborne exposure does not exceed 0.1 mg/m³
Engineering Controls: High-efficiency dust extraction, local ventilation, closed process equipment, isolation panels if available
Personal Protective Equipment (PPE): Laboratory coat, nitrile gloves, safety goggles, respiratory mask for powder handling
Special Controls: Eye wash stations and emergency showers on site; avoid skin and eye exposure
Environmental Controls: Prevent release to the environment; handle spillages according to emergency procedures
Appearance: White to off-white fine crystalline powder
Odor: Odorless or faint chemical odor
pH (1% solution): 6 to 8
Solubility: Freely soluble in water, slightly soluble in methanol, insoluble in chloroform
Melting Point: Decomposes above 180°C (typically no clear melting point)
Boiling Point: Degrades before boiling
Flash Point: Not applicable (non-volatile solid)
Explosive Properties: Not classified as explosive but fine dust may ignite in extreme circumstances
Vapor Pressure: Not applicable
Density: About 1.5 g/cm³
Chemical Stability: Stable under recommended storage and handling conditions
Decomposition: Decomposes with heat, light, or exposure to acidic/alkaline conditions
Incompatible Materials: Strong acids and bases, oxidizing or reducing agents
Hazardous Polymerization: Not expected under normal conditions
Hazardous Decomposition: Carbon dioxide, carbon monoxide, nitrogen oxides, sulfur oxides, sodium oxides
Conditions to Avoid: Moisture, elevated temperatures, direct sunlight, mechanical shock
Routes of Entry: Inhalation, ingestion, dermal, ocular
Acute Toxicity: LD50 (oral, rat) approximately 3,000 mg/kg; moderate toxicity
Chronic Exposure: Potential for allergic reactions, skin sensitization, and disturbance to gut flora
Carcinogenicity: No reliable animal or human data indicate direct risk, yet ongoing monitoring recommended
Mutagenicity: Not shown in routine bacterial or mammalian test systems, follow strict pharmaceutical hygiene
Symptoms: Nausea, vomiting, diarrhea, respiratory symptoms, allergic rash, anaphylaxis in susceptible persons
Aquatic Toxicity: Low to moderate; harmful to aquatic microorganisms and may disrupt microbial populations at higher concentration
Persistence and Degradability: Not readily biodegradable; risk of environmental persistence
Bioaccumulation Potential: Low, due to low lipophilicity
Mobility in Soil: Moderate mobility in water-rich soils
Adverse Environmental Effects: May contribute to antibiotic resistance or ecological imbalance if released
Precautions: Prevent large-scale environmental contamination; avoid discharge into drains or sewers
Waste Treatment Methods: Dispose as hazardous pharmaceutical waste using licensed contractor
Product Disposal: Incinerate in chemical incinerator, following local, state, and federal guidelines
Container Disposal: Decontaminate and triple-rinse containers; dispose according to hazardous waste regulations
Special Instructions: Never discharge unused product or washings into waterways or sewers; use closed waste systems in facilities
UN Number: 3249
Proper Shipping Name: Pharmaceutical chemical, solid, toxic, n.o.s (contains Latamoxef Sodium)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Labels Required: Toxic Substances
Sea Transport (IMDG): Follows standard packaging and labeling rules
Air Transport (IATA): Follows packaging regulations for pharmaceuticals
Special Precautions: Keep away from direct sunlight and moisture during transport; pack securely to avoid movement and breakage
OSHA Status: Not specifically listed; regulated as hazardous under general duty clause
TSCA Inventory: Not listed due to pharmaceutical use
WHMIS Classification: D2B (Toxic materials causing other toxic effects)
EU Regulation: Classified as hazardous medicine; subject to Regulation (EC) No 1272/2008 (CLP)
Risk Phrases: Harmful if swallowed, may cause sensitization, risk of serious damage to eyes
SARA Title III: Not listed under Section 313
Other Requirements: Facility must provide training for potential handlers, maintain medical monitoring for personnel, and follow strict record-keeping for inventory and incident response
