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Name: L-Theanine
Chemical Formula: C7H14N2O3
Common Appearance: White crystalline powder
Main Use: Found in tea leaves, often added to supplements for its calming effects
Odor: Usually odorless, not typically irritating
Solubility: Dissolves in water, not especially tricky to work with in most labs or supplement factories
Synonyms: Gamma-glutamylethylamide, N5-ethyl-L-glutamine
Other Names: Natural presence in tea, especially green tea, also produced synthetically for broader use
Common Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Effects: Mild irritation possible with dust contact on eyes or skin; not classified as hazardous for most handling
Chronic Effects: Health authorities rate toxicity as low for normal use; accidental large intake might cause stomach upset
Possible Signs of Overexposure: Discomfort, minor coughing or sneezing if powder becomes airborne
Occupational Risk: Sensible to avoid breathing in dust or rubbing it into your eyes; rare to see long-term problems in responsible use
Main Component: L-Theanine around 99% purity in supplement-grade batches
Impurities: Trace moisture, trivial organic residues depending on manufacturing
Mixtures: Rarely supplied as a blend, more often a pure component for blending by supplement makers
Inhalation: Move person to fresh air, rinse mouth, monitor for breathing difficulty
Skin Contact: Wash with soap and water, take off contaminated clothing
Eye Contact: Rinse well with water, blink to help removal, see a doctor if irritation lingers
Ingestion: Rinse mouth, drink water for dilution, unlikely to cause severe harm in reasonable doses, medical help only needed if unlikely symptoms appear
Flammability: Not highly flammable, but can contribute to combustion if exposed to open flame
Suitable Extinguishing Media: Basic foam, dry powder, CO2, or water spray
Hazardous Combustion Products: Can give off nitrogen oxides or carbon oxides if burning
Special Protective Equipment: Standard fire gear with self-contained breathing air; avoid breathing smoke
Firefighting Precautions: Try to keep containers cool using water spray to prevent pressure increase
Personal Precautions: Gear up with gloves and dust masks to block inhalation
Spill Cleanup: Sweep up without raising dust; gather spills for disposal in labeled container
Ventilation: Fans or open windows in enclosed spaces cut down on dust
Environmental Concerns: Not particularly hazardous to waterways in small amounts, but sensible disposal avoids unnecessary exposure for wildlife
Handling: Try to keep dust down, use gloves, and avoid eating or drinking in work area
Storage Conditions: Cool, dry place, containers sealed tightly to keep moisture and contaminants out
Incompatible Materials: Keep away from strong acids, oxidizers, common sense storage for organic compounds
Special Advice: Store off the ground and out of direct sunlight; label containers clearly
Engineering Controls: Local exhaust for dusty operations
Personal Protection: Dust masks, basic chemical-resistant gloves, safety glasses for bulk handling or powder transfers
Hygiene Measures: Wash hands well after use, don’t touch eyes or face with contaminated hands
Exposure Limits: There are no specific legal exposure limits set by OSHA or similar agencies; risk considered low for reasonable workplace use
Appearance: White crystalline powder
Solubility: Easily dissolves in water, hard to dissolve in oils or fats
Melting Point: Around 174°C to 176°C
Odor: Almost none
pH: Neutral to mildly basic in water solution
Boiling Point: Not meaningful since it decomposes before boiling
Density: Close to 1.2 grams per cubic centimeter
Stability: Stable when kept dry and at room temperature
Hazardous Polymerization: Not a concern for L-theanine
Reactivity: Not especially reactive under normal lab or workplace conditions
Decomposition Products: Ammonia, carbon dioxide, and other basic gases if burned or seriously overheated
Acute Toxicity: Low, with little evidence of harm from reasonable intake or workplace exposure; animal studies find high safety margin
Skin/Eye Irritation: Only mild and temporary if it happens at all
Inhalation: Mild irritation possible if dust gets airborne and is breathed in
Sensitization: No strong data suggesting allergy risk
Long-Term Effects: No evidence for cancer, genetic impacts, or permanent toxin buildup
Environmental Fate: Degrades easily in water and soil
Aquatic Toxicity: No evidence of harm to water organisms at environmental concentrations from normal dietary wastes
Bioaccumulation: Not likely, easily metabolized by common organisms
Soil Mobility: Moves with water but breaks down before causing concern
General Disposal: Small amounts can go with regular lab or facility waste; larger batches through licensed chemical waste processes
Special Consideration: Contaminated packaging should be triple rinsed or trash disposed under normal conditions
Environmental Releases: Routine disposal avoids water drains; no hazardous legacy expected in landfill
UN Number: Not classified as hazardous for transport
Shipping Name: L-theanine (or “Amino acid supplement”)
Primary Hazard Class: None
Packing Group: Not regulated
Special Precautions: Pack in sturdy containers to avoid breakage and dust spreading; keep paperwork handy to clarify its non-hazardous nature during checks
GHS Classification: Generally not classified as dangerous
US EPA: No significant regulatory concerns
EU: Safe for food or supplement use, must comply with regulations on purity and product labeling
Other Regions: National health authorities oversee use in supplements; rules may differ, but theanine stays clear of the more restrictive toxic substance laws
Workplace Safety: Simple requirement for labeling and training on safe handing, no advanced controls demanded by law for standard quantities
