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Product Name: L-Ornithine Hydrochloride
Chemical Formula: C5H12ClN2O2
Synonyms: 2,5-Diaminovaleric acid monohydrochloride
CAS Number: 3184-13-2
Recommended Use: Nutritional supplement, research and biochemical preparations
Supplier Information: Contact details, emergency phone number, and address should be accessible by those storing or using the substance in academic, industrial, or manufacturing settings.
Classification: Not classified as hazardous under GHS guidelines. Monitoring for chronic exposure or concentration in dust form helps minimize potential respiratory tract irritation.
Label Elements: No pictogram, warning, or precautionary statement mandated under standard laboratory use.
Health Hazards: May cause mild eye, skin, or respiratory irritation on contact or inhalation.
Environmental Hazards: Low expected risk for acute or chronic toxicity in typical quantities.
Physical Hazards: Not flammable or explosive, but powder handling may generate nuisance dust.
Chemical Name: L-Ornithine Hydrochloride
Percent Composition: 100% pure
Impurities: No hazardous impurities expected when supplied for laboratory, research, or food grade use.
Molecular Weight: 170.62 g/mol
Inhalation: Move affected person to fresh air. Seek medical attention if coughing or irritation persists.
Skin Contact: Remove contaminated clothing. Wash skin with water and mild soap. Avoid prolonged contact.
Eye Contact: Rinse with plenty of water for several minutes. Remove contact lenses. Seek medical advice if irritation or redness continues.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by a healthcare professional. Get medical attention for significant discomfort or persistent symptoms.
Notes to Physician: Treat symptomatically based on patient’s condition.
Extinguishing Media: Use dry chemical, carbon dioxide, water spray, or foam as appropriate for surroundings.
Specific Fire Hazards: Decomposition may release nitrogen oxides, hydrogen chloride, or carbon oxides at high temperatures.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear.
Advice for Firefighters: Cool adjacent containers with water spray in cases of significant fire exposure.
Personal Precautions: Wear gloves, goggles, and laboratory coat during cleanup. Prevent inhalation of dust.
Environmental Precautions: Avoid bulk transfer into drains or natural water sources. Use containment to prevent spreading.
Cleanup Methods: Sweep up solid or powder material, transfer to a sealed waste container. Minimize dust generation and ventilate the area. Dispose according to regulations.
Decontamination: Wash area of spill with water after removal.
Handling: Avoid generating and breathing dust. Wear appropriate protective gear like safety glasses and gloves. Always wash hands after use.
Storage: Store in tightly closed containers in a dry, cool, well-ventilated location away from direct sunlight and moisture.
Incompatibilities: Keep away from strong oxidizing or reducing agents.
Safety Practices: Train personnel on safe handling procedures. Keep location information posted for reference.
Exposure Limits: No established limits from OSHA, ACGIH, or NIOSH.
Engineering Controls: Use local exhaust ventilation for bulk handling and weighing. Use dust controls where necessary.
Respiratory Protection: Simple dust mask or respirator may be required if high dust concentration is unavoidable.
Eye Protection: Chemical safety goggles recommended.
Hand Protection: Nitrile or latex gloves for laboratory and industrial handling.
Other Protection: Laboratory coat or coverall to minimize skin contact.
Hygiene Measures: Do not eat, drink, or smoke during use. Wash hands before breaks and after handling.
Appearance: White crystalline powder
Odor: Odorless
pH (solution): 4.0 - 5.5 in water
Melting Point: 220–235°C (decomposes)
Solubility: Freely soluble in water; insoluble in organic solvents like ethanol or ether
Vapor Pressure: Not relevant at ambient temperatures
Density: 1.69 g/cm³
Partition Coefficient (log Kow): Not expected to bioaccumulate
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: No particular reactivity risk known for normal laboratory or warehouse storage.
Incompatibility: Strong oxidizers, acids, and bases may cause degradation.
Hazardous Decomposition Products: At high temperature, expect possibility of nitrogen oxides, carbon oxides, hydrogen chloride.
Polymerization: Hazardous polymerization does not occur.
Acute Toxicity: Not expected to be acutely toxic by oral, inhalation, or dermal exposure in small volumes. LD50 (oral, rat) > 2000 mg/kg.
Irritation: May cause mild, reversible irritation to eyes or skin in sensitive individuals.
Sensitization: Not expected to cause skin or respiratory sensitization.
Long-Term Effects: No known carcinogenic, mutagenic, reproductive, or organ toxicity associated with L-ornithine hydrochloride.
Target Organs: No evidence of systemic organ damage from low-dose exposure.
Ecotoxicity: Low risk for aquatic or terrestrial organisms due to biodegradability and low toxicity.
Mobility: Soluble in water; unlikely to persist in soil or sediment.
Persistence and Degradability: Readily biodegradable under environmental conditions.
Bioaccumulation: Does not bioaccumulate.
Other Adverse Effects: No substantial ozone depletion, photochemical, or other atmospheric effect.
Waste Management: Dispose in accordance with local, regional, and national regulations. Use approved waste facilities; do not dump into environment, sewers, or public waterways.
Container Disposal: Triple rinse non-contaminated containers before recycling or disposal. Contaminated containers should be treated as chemical waste and incinerated or disposed by licensed contractors.
Special Considerations: Keep waste records and reporting for regulatory inspection.
UN Number: Not regulated as a hazardous material for air, ground, or marine shipment.
Proper Shipping Name: L-Ornithine Hydrochloride
Hazard Class: Non-hazardous
Packing Group: None
Labeling: No special labeling or marking requirements.
Transport Precautions: Use sealed, robust packaging to prevent spillage or dust release during transit.
Global Inventories: Substance listed or exempt on major chemical inventories, including TSCA (US), EINECS (EU), ENCS (Japan), and DSL (Canada).
OSHA Hazard Communication: Not classified as hazardous; SDS communication suggested.
SARA Title III: Not subject to reporting under Sections 302, 304, or 313.
California Prop 65: Not listed as a carcinogen or reproductive toxin.
Workplace Labeling: Use common chemical identification and hazard language as recommended by GHS.
International Regulations: World Health Organization (WHO) and Food Chemicals Codex accept L-ornithine hydrochloride for dietary use within set purity guidelines.
