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Product Name: L-Mandelic Acid
Chemical Name: (S)-2-Hydroxy-2-phenylacetic acid
CAS Number: 17199-29-0
Synonyms: Mandelic acid, alpha-Hydroxybenzeneacetic acid
Recommended Use: Intermediate in pharmaceutical synthesis, cosmetics, chemical research
Supplier Details: Manufacturer’s contact information, emergency phone numbers, and address (must check updated labels or reach out directly to the supplier for specifics).
Classification: Eye irritation, category 2A; skin irritation, category 2.
GHS Label Elements: Hazard pictogram: Exclamation mark. Signal word: Warning.
Hazard Statements: Causes serious eye irritation. May cause skin irritation.
Precautionary Statements: Wash hands thoroughly after handling. Wear protective gloves and eye protection. In case of contact with eyes, rinse cautiously with water. If skin irritation occurs, seek medical advice.
Other Hazards: Dust generation may irritate respiratory system.
Chemical Identity: L-Mandelic acid
CAS Number: 17199-29-0
Percentage: Greater than 98%
Impurities/Additives: Trace solvents or manufacturing by-products may occur at levels below 1% (varies between suppliers).
Inhalation: Move person to fresh air. Provide oxygen or artificial respiration if breathing difficulty appears. Seek immediate medical attention in severe exposure.
Skin Contact: Remove contaminated clothing. Rinse skin with soap and plenty of water for at least 15 minutes. If irritation develops or persists, consult a physician.
Eye Contact: Flush eyes gently under running water for at least 20 minutes, keeping eyelids open. Remove contact lenses if present. Seek prompt medical attention.
Ingestion: Rinse mouth thoroughly. Drink water, avoid inducing vomiting unless directed by medical personnel. Immediate medical advice recommended.
Other Notes: Emergency responders need to use personal protective equipment.
Suitable Extinguishing Media: Use dry chemical, water spray, carbon dioxide, or foam extinguishers.
Unsuitable Media: Avoid using direct streams of water, which can spread material.
Fire Hazards: Decomposition may release hazardous gases like carbon monoxide and carbon dioxide under fire conditions.
Protective Equipment: Firefighters use self-contained breathing apparatus and appropriate turnout gear.
Other Instructions: Move containers from area if safe. Avoid inhalation of combustion products. Cool exposed containers with water spray.
Personal Precautions: Wear gloves, eye protection, and dust mask. Remove ignition sources and provide adequate ventilation.
Environmental Precautions: Prevent runoff into drains or water sources. Stop spread using dry sand or earth.
Clean-Up Methods: Sweep up spilled material carefully to minimize dust. Collect in suitable, labeled containers for disposal, then rinse area with water. Use industrial vacuum rather than dry brushing where possible.
Other Tips: Dispose of all cleaning materials following local and federal guidelines.
Precautions for Safe Handling: Handle in well-ventilated spaces. Avoid unnecessary contact with skin, eyes, or clothing. Do not eat, drink, or smoke around product.
Storage Conditions: Store container tightly closed in cool, dry place, away from incompatible materials like strong bases, oxidizers.
Special Storage Requirements: Use corrosion-resistant shelving and ensure secondary containment for bulk quantities. Protect from light and high temperatures.
Hygiene Measures: Clean clothing and wash skin thoroughly after use.
Occupational Exposure Limits: No specific national or international exposure limits established, but minimize dust exposure.
Engineering Controls: Use local exhaust ventilation. Enclose processes if possible to limit airborne dust.
Personal Protective Equipment:
- Eyes: Safety goggles with side-shields
- Skin: Impervious gloves and lab coat or apron
- Respiratory: NIOSH-approved dust mask in dusty conditions
- Hygiene: Remove contaminated garments; wash hands before breaks and after use
Appearance: White crystalline powder
Odor: Little or no odor
Molecular Formula: C8H8O3
Molecular Weight: 152.15 g/mol
Melting Point: 120-122°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, ethanol, ethyl acetate
pH: Acidic in water solution
Vapor Pressure: Negligible at room temperature
Density: About 1.3 g/cm3
Partition Coefficient (log Kow): 1.28
Chemical Stability: Stable under recommended conditions of storage and use
Conditions to Avoid: Heat, ignition sources, moisture, strong light
Incompatible Materials: Strong oxidizing agents, strong bases, nitrates
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide form at high temperatures
Potentially Hazardous Reactions: No dangerous reactions under normal conditions but can react with strong oxidizers or bases
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: LD50 (oral, rat): Approximately 3000 mg/kg
Symptoms: Irritation of eyes, skin, respiratory tract; possible gastrointestinal disturbances; redness and discomfort on contact
Chronic Effects: No substantial data on chronic toxicity; repeated exposure may increase risk of irritation
Sensitization: No reported allergic reactions
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not considered carcinogenic; no evidence of mutagenic or reproductive impacts based on available data
Ecotoxicity: Low acute toxicity expected for aquatic life; no significant bioaccumulation anticipated
Mobility in Soil: Likely to be moderately mobile due to water solubility
Persistence and Degradability: Biodegradable in nature over time under aerobic conditions
Environmental Concerns: Prevent large quantities from entering waterways to avoid localized effects
Waste Disposal Methods: Dispose as hazardous waste in accordance with local, regional, and national regulations
Container Disposal: Rinse completely with water; place in appropriately labeled waste containers
Recommendations: Incineration preferred for bulk waste; smaller quantities go to chemical waste collection points; avoid release to environment
UN Number: Not classified as hazardous for transport
Proper Shipping Name: Mandelic Acid
Transport Hazard Class: Not regulated
Packing Group: Not assigned
Special Precautions: Protect from physical damage, moisture, and extreme temperatures during transit
TSCA: Listed on the United States Toxic Substances Control Act inventory
REACH: Pre-registered with European Chemicals Agency (ECHA)
Other Regulatory Listings: L-Mandelic Acid appears in multiple international chemical inventories; not subject to export controls or special restrictions in major regions
Labelling Requirements: Follow GHS labeling with appropriate warnings and pictograms
Other Notes: Further local restrictions may apply; users confirm compliance with applicable regional regulations before purchase, use, and disposal
