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Product Name: L-Glutamine
Chemical Name: (S)-2,5-Diamino-5-oxopentanoic acid
Synonyms: Glutamic acid, 2-amino-4-carbamoylbutanoic acid
CAS Number: 56-85-9
Recommended Use: Pharmaceutical manufacturing, laboratory reagents, nutritional supplements
Supplier: Stated by manufacturer on container label
Contact Number: Refer to accompanying packaging labels for local contact
GHS Classification: Not classified as hazardous
Hazard Statements: Not considered hazardous according to OSHA HCS (2012)
Hazard Symbol: None required
Precautionary Statements: Avoid contact with eyes or prolonged skin exposure, avoid inhalation of dust
Potential Health Effects: Slight irritation in sensitive individuals on skin or eye contact, no significant effect reported from ingestion at standard concentration
Signal Word: None
Chemical Name: L-Glutamine
Formula: C5H10N2O3
Purity: Typically ≥ 98%
Impurities: Trace amounts of enantiomers or other amino acids may be present based on source
Ingredient Type: Single component substance
Concentration: 100% (unless listed as blended formulation)
Inhalation: Remove person to fresh air; seek medical attention if irritation or difficulty breathing occurs
Skin Contact: Wash with soap and water; remove contaminated clothing
Eye Contact: Immediately flush eyes with large amounts of water for at least 15 minutes; seek medical attention if irritation persists
Ingestion: Rinse mouth; drink water to dilute; seek medical assistance if feeling unwell persists
Notes to Physician: Treat symptomatically
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Media: None known
Hazardous Combustion Products: Carbon oxides, nitrogen oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus and protective clothing
Specific Hazards: Dust can form explosive mixtures with air if significant quantities become airborne in a confined space
Personal Precautions: Avoid dust formation; ventilate area; wear appropriate PPE
Environmental Precautions: Prevent entry into drains, sewers, watercourses
Methods for Containment: Sweep up without creating dust, place in suitable waste container
Cleaning Procedures: Minor residues can be wiped up with damp cloth; larger spills need vacuum or soft brush with personal protection; wash area after cleanup
Disposal: Dispose in accordance with local, regional, and national regulations
Handling: Keep container tightly closed; avoid dust generation; use in well-ventilated area
Storage Conditions: Keep in cool, dry, and well-ventilated place; protect from light and moisture; store away from incompatible substances
Incompatible Materials: Strong oxidizers
Hygiene Practices: Wash hands thoroughly after handling; do not eat, drink or smoke during use; wash contaminated clothing before reuse
Exposure Limits: No occupational exposure limit values established by OSHA, ACGIH, or NIOSH
Engineering Controls: Use local exhaust ventilation if dust or aerosols are generated
Personal Protective Equipment: Safety goggles, lab coat, gloves (nitrile or latex), dust mask or respirator in case of insufficient ventilation
Environmental Exposure Controls: Minimize release to environment; adhere to local emission guidelines
Appearance: White crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH (1% solution): 4.5 - 6.0
Melting Point: Approximately 185°C (decomposes)
Boiling Point: Decomposes prior to boiling
Flash Point: Not applicable
Flammability: Not classified as flammable
Explosive Properties: Dust may present an explosion hazard in air under specific conditions
Vapor Pressure: Negligible
Solubility: Water soluble, slightly soluble in alcohol
Partition Coefficient (n-octanol/water): -3.0 (estimated)
Auto-Ignition Temperature: Not available
Decomposition Temperature: >185°C
Relative Density: Approx. 1.47 g/cm³
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: No dangerous reactions known under normal conditions
Possibility of Hazardous Reactions: None expected with typical use
Conditions to Avoid: Excessive temperature, contact with strong oxidizers, moisture exposure
Incompatible Materials: Strong oxidizers
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides under fire conditions
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: LD50 (oral, rat): >8,000 mg/kg
Skin Corrosion/Irritation: Mild irritation possible in sensitive individuals
Eye Damage/Irritation: Mild irritation may occur
Respiratory or Skin Sensitization: No data supporting allergic sensitization
Germ Cell Mutagenicity: Not classified as mutagenic
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence of adverse effects
Delayed/Chronic Effects: Not identified under recommended handling
Ecotoxicity: Expected low hazard to the aquatic environment; not classified as hazardous
Persistence and Degradability: Readily biodegradable under environmental conditions
Bioaccumulative Potential: Low, does not accumulate in organisms
Mobility in Soil: High mobility due to water solubility
Other Adverse Effects: None known, avoid large-scale release
Waste Treatment Methods: Send to authorized disposal facility with appropriate labeling
Disposal of Packaging: Rinse empty containers and recycle or dispose as per local regulations
Special Precautions: Do not release to environment in unregulated quantities
Regulatory Status: Non-hazardous waste under US RCRA regulations, unless contaminated with hazardous materials
UN Number: Not regulated for transport
Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: None
Transport in Bulk: Not applicable
Special Precautions for User: Protect from moisture during transit; avoid excessive heat
US Regulations: Not listed as hazardous under TSCA, SARA Title III, CERCLA
EU Regulations: Not classified as hazardous under EC No. 1272/2008
Canada: Not listed as controlled product under WHMIS
Other Chemical Inventories: Listed on most national chemical inventories (TSCA, EINECS, ENCS, DSL, AICS)
Label Elements: Safety labeling not required for workplace handling in standard quantities
