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Product Name: L-Aspartic Acid Diethyl Ester Hydrochloride
Chemical Formula: C8H16ClNO4
CAS Number: 1065-06-3
EC Number: 213-917-2
Synonyms: Diethyl L-Aspartate HCl, L-Aspartic Acid, diethyl ester, hydrochloride
Recommended Use: Pharmaceutical Intermediates, Chemical Research
Manufacturer Contact: Available with supplier, including emergency phone hotline on SDS
GHS Classification: Not classified as hazardous under GHS criteria
Signal Word: None
Hazard Statements: May cause mild irritation to eyes or skin upon contact, possible respiratory tract irritation on dust inhalation
Precautionary Statements: Avoid breathing dust, wash exposed area thoroughly after handling, use in well-ventilated area
Pictograms: None for this classification
Potential Health Effects: Prolonged skin or eye exposure may lead to redness or discomfort; accidental ingestion could lead to mild gastrointestinal symptoms
Chemical Name: L-Aspartic Acid Diethyl Ester Hydrochloride
Concentration: ≥98% (typical)
Impurities: Traces of unreacted starting material, solvents used for purification
Other Components: No known hazardous impurities present above regulatory disclosure limits
Inhalation: Remove subject to fresh air, monitor breathing, get medical help if symptoms persist
Skin Contact: Wash affected area with plenty of soap and water, remove contaminated clothing, seek medical attention for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, consult ophthalmologist if irritation occurs
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice if feeling unwell
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam, water spray
Unsuitable Extinguishing Media: High-pressure water jets may scatter material
Specific Fire Hazards: Combustion could produce carbon monoxide, carbon dioxide, nitrogen oxides, hydrogen chloride gas
Protective Equipment: Firefighters should wear self-contained breathing apparatus, full protective gear
Special Precautions: Move containers away from fire area if safe, cool exposed containers with water
Personal Precautions: Wear protective gloves, eye protection, and dust mask to prevent exposure
Environmental Precautions: Prevent further leakage or spillage if safe, avoid discharge into drains or water sources
Methods for Cleanup: Sweep up and collect spilled material using non-sparking tools, place in labeled container for disposal, ventilate area and wash spill site after material pickup
Safe Handling Advice: Handle with care in a well-ventilated area, minimize dust generation and accumulation, avoid direct contact with skin, eyes, or clothing
Storage Conditions: Store in original tightly sealed container, keep in cool, dry place away from incompatible materials like oxidizers and acids, protect from moisture
Storage Temperature: Recommended storage below 25°C, away from sources of heat or direct sunlight
Packaging Materials: Compatible with polyethylene, glass, or plastic containers lined with PVDF
Occupational Exposure Limits: No established limits for this compound
Engineering Controls: Use local exhaust ventilation or fume hood to prevent accumulation of airborne dust or vapors
Personal Protective Equipment: Chemical-resistant gloves (nitrile or latex), lab coat or apron, safety goggles, suitable dust respirator if airborne levels exceed exposure guidelines
Hygiene Measures: Wash hands and face after handling, do not eat, drink, or smoke during use, keep contaminated clothing separate and launder before reuse
Appearance: White crystalline powder
Odor: No characteristic odor
Melting Point: 142–145°C
Boiling Point: Decomposes prior to boiling
Solubility: Soluble in water, moderately soluble in methanol or ethanol
pH Value: 3.0–4.5 (5% solution in water)
Vapor Pressure: Negligible at room temperature
Partition Coefficient (Log Kow): Data not available
Flash Point: Not applicable
Autoignition Temperature: Data not available
Density: 1.22 g/cm³ (25°C)
Molecular Weight: 225.68 g/mol
Chemical Stability: Stable under normal temperature and handling conditions
Stability Notes: May degrade if exposed to moisture, acids or heat
Hazardous Reactions: No data for hazardous polymerization or incompatibility with most common laboratory reagents
Incompatible Materials: Strong oxidizing agents, strong acids or bases
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, hydrogen chloride upon combustion or decomposition
Conditions to Avoid: Sources of ignition, excessive heat, moisture, prolonged exposure to air
Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Effects: Low toxicity by oral or dermal route, may cause mild transient irritation to mucous membranes
Sensitization: No evidence of sensitization or allergic reaction in animal studies
Chronic Effects: No long-term toxicological data recorded, not known to cause heritable genetic damage or carcinogenicity
LD50 (estimate): Greater than 2000 mg/kg (rat, oral)
Mutagenicity/Carcinogenicity: Not classified as mutagenic or carcinogenic by IARC, NTP, or OSHA
Symptoms of Overexposure: May include cough, mild nausea, skin redness, eye discomfort
Ecotoxicity: Not expected to pose significant hazards to aquatic or terrestrial organisms at low concentrations
Persistence and Degradability: Readily biodegradable under environmental conditions
Bioaccumulative Potential: Low potential for accumulation in living organisms
Mobility in Soil: Expected to exhibit moderate mobility in soil due to water solubility
Other Effects: Avoid direct release to water courses or sewage systems to minimize localized environmental burden
Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations; transfer waste to a licensed chemical incinerator with afterburner and scrubber
Packaging Disposal: Containers should be emptied completely and rinsed, then disposed through approved waste contractors
Hazardous Waste Code: Not assigned for this substance in many jurisdictions, but handle as chemical waste
UN Number: Not regulated for transport as a hazardous material
Proper Shipping Name: Chemical, non-hazardous
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not applicable
Marine Pollutant: No
Special Transport Precautions: Protect from moisture during transport, use sealed containers, avoid stacking heavy loads on top to prevent spillage
TSCA Status: Listed or exempt
REACH Status: Registered, pre-registered or exempt from registration
Canadian DSL/NDSL: Present on the Domestic Substances List
OSHA Hazards: Not regulated
Other Regulations: Not listed as a controlled drug or substance, no reporting requirements under SARA Title III or California Proposition 65
Label Phrases: Handle in accordance with good industrial hygiene and safety practices, not intended for food, drug, or household use
