© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Kanamycin Disulfate
Chemical Formula: C18H36N4O11S2
CAS Number: 25389-94-0
Synonyms: Kanamycin sulfate, Kanamycin A disulfate salt
Recommended Use: Antibiotics in microbiological and cell culture applications
Manufacturer: Leading global chemical suppliers
Contact Details: Emergency phone and standard support lines, listed both locally and internationally; details referenced on original packaging.
Classification: Eye irritation (Category 2A), Skin sensitizer (Category 1), Potential respiratory tract irritant
Label Elements: Warning pictogram for exclamation mark; phrases alerting for skin and eye irritation; precaution to avoid dust inhalation
Hazard Statements: May cause allergy or asthma symptoms, intense coughing with prolonged exposure, rash upon skin contact; inflammation of eyes reported in occupational settings
Precautionary Statements: Recommend gloves, lab coat, and safety glasses during handling; avoid dust generation; seek fresh air after exposure; use local exhaust ventilation where possible.
Main Ingredient: Kanamycin Disulfate
Concentration: Approximately 97–102% active per labeling, purity specifications, minor organic or sulfate impurities
Impurities & Additives: Possibility of minute trace residuals from synthesis; no known protein, DNA, or common allergenic contaminants
Inhalation: Remove to open space, encourage slow and deep breaths, seek medical care if coughing lingers or breathing difficulty persists
Skin Contact: Remove contaminated clothing, flood exposed area with water at least 15 minutes, wash using non-caustic mild soap, review for rash or irritation after drying
Eye Contact: Hold eyelids open and rinse gently under flowing water for an extended period, at least 15 minutes; consult medical attention regardless of lingering symptoms
Ingestion: Rinse mouth with copious water, avoid inducing vomiting, seek medical advice if symptoms like nausea or abdominal discomfort occur; report circumstances (amount, time) to attending healthcare staff.
Suitable Extinguishing Media: Water spray, dry chemical powder, carbon dioxide, foam extinguishers
Specific Hazards: Decomposes to emit toxic fumes (nitrogen oxides, sulfur oxides, carbon oxides) when exposed to extreme heat or flames
Firefighting Instructions: Use full protective turnout gear as respiratory exposure may risk long-term lung issues, apply water fog in short bursts to minimize spreading contaminated powder
PPE for Firefighters: Positive-pressure NIOSH-approved self-contained breathing apparatus, chemical-resistant gloves and boots, no open skin exposed
Personal Precautions: Wear fitted respirator or mask, chemical safety goggles, gloves, and impervious clothing; avoid skin exposure and close-range inhalation
Environmental Precautions: Prevent residue from entering drains, waterways, storm sewers; use physical barriers and absorbent materials
Cleanup Methods: Scoop spilled powder while minimizing dust, sweep or vacuum with HEPA filtration, double-bag collected material for hazardous waste pickup; flush residue with generous amounts of water and mild detergent; properly ventilate affected area.
Handling: Only open containers in well-ventilated rooms or with effective local exhaust; avoid breathing dust, handling with bare skin, or allowing accidental ingestion; train staff with the most recent guidelines
Storage: Store below 8°C for extended stability, away from direct light, heat, acids, oxidizers, and food prep zones; keep in original airtight container or well-sealed amber bottle featuring risk communication labels; check for visible moisture or color changes on regular schedule
Engineering Controls: Designate work under fume hood or local extraction; HEPA filtration and room air monitoring provide added safety; never pipette by mouth
Personal Protective Equipment: Wear goggles, solvent-resistant gloves, fitted lab coat or gown, closed footwear, and NIOSH approved dust mask
Hygiene Measures: Never eat, drink, or smoke in storage or working areas; thorough hand washing required after handling; avoid touching face or skin before decontamination; dedicate cleaning schedule for work surfaces.
Form: White to off-white crystalline powder
Odor: Odorless or faint medicinal scent
pH: Neutral to slightly acidic when dissolved in water
Melting Point/Range: Decomposes without distinct melting below 250°C
Solubility: Freely soluble in water, nearly insoluble in organic solvents
Boiling Point: Not applicable as decomposition occurs
Relative Density: Around 1.8 g/cm³ for dry solid
Other Properties: No significant vapor pressure; stable under normal ambient conditions if kept sealed from moisture and direct sunlight.
Chemical Stability: Stable under manufacturer-recommended storage conditions, sensitive to prolonged moisture or warmth
Incompatible Materials: Strong oxidizing agents, concentrated mineral acids, selected heavy metals can trigger unwanted reactivity
Hazardous Decomposition Products: Sulfur oxides, carbon monoxide or dioxide, nitrogen oxides, ammonia compounds produced at elevated temperatures
Conditions to Avoid: Excess heat, direct sunlight, exposure to acidic or oxidizing environments, high humidity
Likely Routes of Exposure: Inhalation of airborne powder, skin absorption, eye and mucous membrane contact, accidental ingestion
Toxicity Data: LD50 Oral (rat): approximately 5500 mg/kg; large exposures may cause nephrotoxicity or ototoxicity as documented in clinical use
Symptoms: Short-term effects: coughing, minor nausea or gastrointestinal upset, skin or eye redness; long-term or large-dose exposure may impair hearing or renal function
Carcinogenicity: No evidence supporting classification as a carcinogen
Sensitization: Repeat exposure may trigger dermatologic or respiratory allergic reactions in some individuals.
Ecotoxicity: Risk of toxicity to aquatic organisms at modest concentrations, potential to inhibit microbial and algal populations in effluent
Persistence and Degradability: Slowly biodegradable in aquatic and soil conditions, moderate risk for long-term environmental exposure
Bioaccumulation Potential: Low likelihood due to high water solubility and rapid dilution
Mobility in Soil: Moves freely in waterlogged or sandy soils; risk for groundwater exposure; containment and managed waste disposal recommended
Other Effects: May contribute antibiotic resistance in microbial communities if disposal protocols ignored.
Waste Disposal: Treat as hazardous laboratory waste; segregate from regular trash, use approved chemical disposal contractors
Method: Dissolve residual powder in water, neutralize per local regulation, collect into labeled biohazard or chemical waste drums; never pour down sink or storm drains
Contaminated Packaging: Rinse empty containers with water, deface all hazard labels, send for professional incineration or landfill disposal as per regulatory guidance.
Local Regulations: Consult respective waste authority for current practices in hazardous pharmaceutical and antibiotic waste streams.
UN Number: Non-dangerous goods under standard regulations (ADR/RID/IMDG/IATA)
Transport Hazard Class: No assigned hazard class, though best managed as bioactive chemical
Packing Group: Not regulated, but double containment in unbreakable outer package required for air or express shipments
Special Precautions: Clearly label outer shipping carton with product name, ensure transport staff are equipped with chemical spill response contacts.
OSHA: Not specifically listed among hazardous substances, though standard laboratory chemical rules apply
TSCA: Kanamycin Disulfate appears on the inventory, recognized for permitted uses in research
REACH/CLP: Substance documented, not classified for restriction under European chemical safety rules
National Inventories: Registered in United States, Canada, Australia, EU, Japan, Korea, China
Other Notes: Check that local occupational safety and environmental protection authorities update their requirements yearly; use Safety Data Sheet revisions published by global suppliers to ensure compliance.
