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Product Name: Isoxaflutole
Synonyms: Balance, Raptor, N-(3-isoxazolyl)-2-(methylsulfonyl)-4-(trifluoromethyl)benzamide
Recommended Use: Herbicide for agricultural applications
CAS Number: 141112-29-0
Manufacturer Contact: Safety, compliance, and emergency support lines listed on the package label
Emergency Phone Numbers: National chemical safety hotlines and poison control resources
Address: Manufacturer’s registered location on product label documents
UN Number: 3077 (for environmental hazards in transport)
GHS Classification: Acute toxicity (Oral) Category 4, Acute aquatic hazard Category 1, Chronic aquatic hazard Category 1
Signal Word: Warning
Hazard Statements: Harmful if swallowed, very toxic to aquatic life with long lasting effects
Pictograms: Exclamation mark, dead fish and tree
Precautionary Statements: Avoid release to the environment, wash hands thoroughly after handling, do not eat or drink while using the product, use personal protection
Physical Hazards: Dust generated by handling can create a fire risk in some conditions
Chemical Name: Isoxaflutole
Active Ingredient Concentration: Varies by formulation, often 75% purity in technical grade
Inert Ingredients: Dispersants, anti-caking agents, surfactants for wettable powders or granules, specific substance details by manufacturer
Impurities: Less than 1% total, not considered relevant for classification based on toxicology review
Inhalation: Move exposed person to fresh air, keep at rest, seek medical attention if respiratory symptoms develop
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical attention immediately, provide product container or label to physician
Skin Contact: Remove contaminated clothing, wash skin with soap and large amounts of water, consult a physician for irritation or allergic reaction
Eye Contact: Rinse thoroughly with water for several minutes, remove contact lenses if present, continue rinsing, seek medical attention for redness or irritation
Symptoms: Nausea, headache, respiratory irritation, eye and skin irritation, rarely more severe symptoms
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam
Specific Hazards: Combustion may release carbon monoxide, sulfur oxides, nitrogen oxides, hydrogen fluoride, toxic fluorinated compounds
Protective Equipment: Self-contained breathing apparatus, protective clothing
Special Instructions: Do not allow contaminated runoff to enter sewers or water sources, cool containers with water spray if exposed to fire
Personal Precautions: Wear chemical-resistant gloves, safety goggles, and dust mask or respirator, avoid breathing dust
Environmental Precautions: Prevent product from entering waterways, drains, or soil, contain spillage with sand, earth, or inert material
Methods for Cleanup: Shovel up material, place in labeled containers for disposal, vacuum dust if possible, ventilate area
Decontamination: Clean contaminated surfaces with detergent, do not reuse cleaned-up material, dispose of in accordance with local regulations
Precautions for Safe Handling: Use with adequate ventilation, avoid creating or inhaling dust, do not mix with incompatible chemicals, wear protective clothing, avoid skin and eye contact, no eating or drinking during use
Conditions for Safe Storage: Keep container tightly closed in a cool, dry, and well-ventilated place, keep away from food, feed, and animal housing, store in original container, label and date containers, protect from direct sunlight and moisture
Incompatibilities: Strong acids, strong bases, strong oxidizers
Occupational Exposure Limits: No established exposure limit for Isoxaflutole, but minimize dust exposure
Engineering Controls: Local exhaust ventilation, general dilution ventilation, enclosed handling when possible
Personal Protective Equipment (PPE): Chemical-resistant gloves, long-sleeved clothing, protective eyewear, filtering facepiece respirator or P2/P3 mask for dust, wash thoroughly after handling
Hygiene Measures: Remove contaminated clothes immediately, do not breathe dust, wash hands and face before breaks or meals
Appearance: Off-white to beige crystalline powder
Odor: Slight characteristic odor
Melting Point: 137–139°C
Boiling Point: Decomposes before boiling
Vapor Pressure: 5.67 × 10⁻⁷ Pa at 25°C
Solubility (Water): 6.7 mg/L at 20°C
Solubility (Other): Soluble in polar organic solvents (methanol, acetone)
Density: 1.5 g/cm³
pH: 7–8 (1% aqueous solution)
Partition Coefficient (log Kow): 2.1
Flash Point: Not flammable
Autoignition Temperature: Not self-igniting
Explosive Properties: Not explosive but fine dust can burn under the right conditions
Oxidizing Properties: Not an oxidizer
Chemical Stability: Stable under normal use and storage conditions
Hazardous Reactions: No hazardous polymerization expected
Conditions to Avoid: Excessive heat, open flames, sparks, incompatible chemicals
Incompatible Materials: Strong acids and bases, potent oxidizers
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, sulfur oxides, hydrogen fluoride, nitrogen oxides, other toxic fumes on combustion
Acute Toxicity: Oral LD₅₀ (rat): 1,790 mg/kg, Dermal LD₅₀ (rat): > 5,000 mg/kg, Inhalation LC₅₀ (rat, 4h): > 4.8 mg/L
Skin Irritation: Slight irritant
Eye Irritation: Mild irritant
Skin Sensitization: Not a sensitizer in standard studies
Chronic Effects: No carcinogenic effects observed in animal studies with prolonged exposure, no evidence of reproductive toxicity at field rates
Other Effects: No reported mutagenicity or teratogenicity in regulatory studies
Toxicity to Fish: LC₅₀ (96h, rainbow trout): 0.04 mg/L
Toxicity to Aquatic Invertebrates: EC₅₀ (48h, Daphnia magna): 0.02 mg/L
Toxicity to Algae: EC₅₀ (72h, green algae): 0.014 mg/L
Persistence and Degradability: Moderately persistent in soil, half-life of 5 to 20 days (depending on conditions), forms degradates that can move in groundwater
Bioaccumulative Potential: Low based on log Kow and bioconcentration factor data
Mobility in Soil: Moderate mobility, leaching potential higher in sandy soils with low organic content
Other Adverse Effects: Highly toxic to non-target aquatic plants, consider drift and runoff controls in agricultural landscapes
Waste Treatment Methods: Collect and contain swept-up product for disposal at a licensed facility, do not dump into sewers or waterways, follow local hazardous waste and pesticide regulations
Container Disposal: Triple rinse empty containers, offer for recycling or dispose of according to national guidelines, do not reuse for any other purpose
Environmental Precautions: Avoid discharge to environment, minimize residual waste, utilize appropriate landfill or incineration options permitted by law
Precautionary Disposal Codes: Check applicable regulatory requirements for classification and safe destruction
UN Number: 3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (contains Isoxaflutole)
Transport Hazard Class: 9 (Miscellaneous dangerous substances and articles)
Packing Group: III
Marine Pollutant: Yes
Special Precautions: Protect against damage, avoid temperature extremes, secure to prevent container spillage while in transit
U.S. EPA Registration: Registered pesticide, subject to tolerance and residue limitations
EU Regulation: Notified substance, use and exposure specifically governed under REACH and Plant Protection Product regulations
Labeling Requirements: GHS-compliant hazard statements, pictograms, precautionary direction on product label
Other Regulations: Subject to Clean Water Act for aquatic protection, SARA Title III reporting, FIFRA labeling, and local chemical safety acts
Worker Protection Standard: User training and PPE required as per agricultural employer rules
