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Product Name: Isopropyl Mercaptan
Chemical Name: 2-Propanethiol
Synonyms: Isopropanethiol, Dimethylmethanethiol
CAS Number: 75-33-2
Recommended Use: Industrial chemical, often used in odorants, laboratory reagents, chemical synthesis
Supplier Information: Manufacturer or distributor details, including emergency contact number, mailing address, and general inquiry phone number
Emergency Phone: Provided by supplier, available 24 hours for chemical emergencies
Classification: Flammable liquid, Acute toxicity (oral, inhalation, dermal), Skin corrosion/irritation, Serious eye damage/irritation, Specific target organ toxicity single exposure
Label Elements: Signal word: Danger, Hazard pictograms: flame, skull and crossbones, exclamation mark
Hazard Statements: Flammable liquid and vapor, Harmful if swallowed, Toxic if inhaled, Causes skin and eye irritation, May cause respiratory irritation
Precautionary Statements: Keep away from heat, sparks, open flames, No smoking, Avoid breathing vapors, Use only outdoors or in a well-ventilated area, Wear protective gloves, protective clothing, eye, and face protection
Main Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Health Effects: Short-term exposure can result in irritation, headaches, coughing, nausea, and dizziness; long-term exposure brings risk of organ damage, possible nervous system effects
Environmental Hazards: Harmful to aquatic organisms, risk of long-term adverse effects in aquatic environment
Chemical Identity: 2-Propanethiol
CAS Number: 75-33-2
Content: 98-100% by weight Isopropyl Mercaptan
Impurities: Contains trace amounts of related sulfur compounds, not expected to alter classification
Stabilizers/Additives: None indicated in technical-grade product
Molecular Formula: C3H8S
Molecular Weight: 76.16 g/mol
Inhalation: Move the exposed person to fresh air, keep at rest, monitor for breathing difficulties, give oxygen if breathing is labored or stops, seek immediate medical help
Skin Contact: Remove contaminated clothing and shoes, flush skin with large amounts of water for at least 15 minutes, wash with soap, do not reuse clothing until properly decontaminated, medical care required if irritation or symptoms develop
Eye Contact: Rinse with gentle stream of water for at least 15 minutes, keep eyelids open, removal of contact lenses if present and easy, seek immediate medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, monitor airway and breathing, seek medical attention immediately, never give anything by mouth to an unconscious person
Symptoms: Headache, nausea, vomiting, respiratory discomfort, skin irritation, eye pain, tearing; in severe cases, drowsiness and unconsciousness
Medical Attention: Special treatment may involve measures against respiratory depression and hypoxia, symptomatic and supportive care recommended
Suitable Extinguishing Media: Dry chemical powder, alcohol-resistant foam, carbon dioxide, water spray used to cool containers; avoid direct water streams
Unsuitable Extinguishing Media: Water jets may spread burning liquid
Special Hazards Arising from the Substance: Highly flammable vapors form explosive mixtures with air, combustion produces sulfur oxides, carbon monoxide, carbon dioxide, highly irritating fumes and gases
Firefighters’ Protective Equipment: Self-contained breathing apparatus, fully protective suit resistant to chemicals, approach from upwind
Other Firefighting Measures: Keep fire-exposed containers cool with water spray, do not allow runoff water to enter drains or waterways, evacuate area and fight fire from a safe distance, take care to prevent static build-up and sparks
Personal Precautions: Evacuate area, keep unnecessary personnel away, ventilate closed spaces before entry, eliminate ignition sources, use non-sparking tools, avoid inhalation and direct contact
Emergency Procedures: Use personal protective equipment including gloves, boots, safety goggles, and respirator approved for organic vapors
Environmental Precautions: Prevent entry into soil, drains, surface water, or groundwater; notify authorities if large spill occurs
Containment: Stop leak if safe to do so, use vapor suppressing foam to reduce vapors, cover spills with inert absorbent (sand, earth, vermiculite), do not flush with water
Clean-Up Methods: Collect absorbed material using non-sparking tools, transfer into labelled drums for safe disposal, ventilate contaminated area thoroughly, wash spill site after material pickup is complete
Safe Handling: Use only in well-ventilated areas, avoid inhalation of vapors and mist, prevent skin and eye contact, ground and bond containers during transfer, keep away from combustible materials, handle away from heat, sparks, flames
Hygiene Measures: Wash hands thoroughly after handling, do not eat, drink, or smoke in work area, contaminated clothing should not leave the workplace
Storage Conditions: Store in a cool, dry, well-ventilated area, keep container tightly closed and properly labelled, separate from incompatible substances like strong oxidizers, acids, and alkalis, store away from direct sunlight
Packaging Materials: Use containers approved for flammable liquids, keep away from materials that may be affected by sulfur compounds, check containers for leaks before storage
Special Requirements: Emergency venting in storage areas, spill containment measures, keep in secondary containment where practical
Occupational Exposure Limits: OSHA PEL: 0.5 ppm, ACGIH TLV: 0.5 ppm (skin)
Engineering Controls: Local exhaust ventilation required to control vapors, explosion-proof ventilation where flammable concentrations may arise, fume hood recommended for laboratory use
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), impervious protective clothing, boots, and apron, chemical splash goggles and face shield
Respiratory Protection: NIOSH/MSHA approved respirator for organic vapors or supplied air respirator if exposure is high or oxygen is limited, respirator programs according to employer and legal standards
Environmental Controls: Install spill containment and vapour suppression systems in high-risk areas, monitor for ambient vapor concentrations using gas detection methods
Work Practices: Minimize exposure duration, strictly follow decontamination routines before leaving work areas
Appearance: Colorless to pale yellow liquid
Odor: Strong, unpleasant, skunk-like odor
Odor Threshold: Detectable at extremely low concentrations (parts per billion), used as odorant due to strong smell
pH: Not applicable
Melting Point: -113.5°C
Boiling Point: 58.4°C
Flash Point: -18°C (closed cup)
Evaporation Rate: Rapid (similar to alcohols, faster than water)
Flammability: Highly flammable liquid
Explosion Limits: Lower: 2.1%, Upper: 19% (in air)
Vapor Pressure: 244 mmHg at 25°C
Vapor Density: 2.6 (air=1)
Relative Density: 0.794 g/cm³ at 20°C
Solubility: Slightly soluble in water, miscible with many organic solvents
Partition Coefficient (log Pow): 1.8
Auto-ignition Temperature: 399°C
Decomposition Temperature: Not specified
Viscosity: Low, similar to other light aliphatic hydrocarbons
Chemical Stability: Stable under normal conditions, product decomposes at elevated temperatures and with exposure to strong acids, bases, or oxidizers
Conditions to Avoid: Heat, flames, sparks, static discharge, direct sunlight
Incompatible Materials: Strong oxidizing agents (peroxides, chlorates, nitrates), acids, alkalis, halogens; contact generates toxic gases, risk of explosion
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, sulfur oxides, hydrogen sulfide, and other toxic or irritating fumes released during combustion
Possibility of Hazardous Reactions: Violent reaction with oxidizers, polymerization does not occur under ambient conditions
Reactivity: Reacts with acids, oxidizers, alkali metals, forming flammable and sometimes toxic gases
Likely Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: Inhalation LC50 (rat): approx. 402 ppm/4h, Oral LD50 (rat): approx. 210 mg/kg, Dermal LD50: data limited but considered harmful
Skin Corrosion/Irritation: Causes redness, dryness, blistering on contact
Serious Eye Damage/Irritation: Causes pain, tearing, conjunctivitis
Respiratory or Skin Sensitization: Limited evidence, not classed as a sensitizer
Specific Target Organ Toxicity (Single Exposure): May affect central nervous system, cause headaches, dizziness, confusion, at high concentrations leads to unconsciousness
Chronic Effects: Prolonged exposure linked to liver, kidney, and nervous system effects
Mutagenicity, Carcinogenicity, Reproductive Toxicity: No conclusive data, not listed by IARC, NTP, or OSHA as a known carcinogen
Other Effects: Unpleasant odor may trigger headaches, vomiting, psychogenic symptoms even at low levels
Medical Conditions Aggravated by Exposure: Pre-existing skin, respiratory, liver, or kidney conditions may be worsened by exposure
Ecotoxicity: Toxic to aquatic life, algae, invertebrates, and fish; observed effect concentrations (LC50, EC50) in the low mg/L range
Persistence and Degradability: Biodegradable in the environment, degrades via oxidation or microbial action in soil and water, persistent sulfurous odor may linger
Bioaccumulative Potential: Low potential, log Kow of 1.8 suggests limited bioaccumulation
Mobility in Soil: High volatility, limited mobility due to evaporation from dry surfaces, some leaching through soil with water
Other Adverse Effects: Risk of tainting groundwater and surface water due to strong smell, accidental release causes public nuisance from odor
Environmental Fate: Oxidizes in atmosphere, ultimately forms sulfate and carbon dioxide, sulfur residues may accumulate temporarily in soils and sediments
Waste Disposal Methods: Incinerate under controlled conditions in a facility permitted for hazardous wastes; land disposal not recommended
Contaminated Packaging: Triple rinse containers, puncture, and send to approved recycler or hazardous waste disposal site, avoid reuse
Precautions for Disposal: Avoid discharge to sewage or surface water, comply with all local, regional, national regulations for hazardous waste
Special Instructions: Consult national or local authority for detailed information, label waste containers, keep incompatible chemicals separated
Other Notes: Do not attempt disposal by combustion in open air, avoid all sources of ignition during packaging and movement of waste
UN Number: 2409
UN Proper Shipping Name: Isopropyl mercaptan
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: I (high danger)
Labels Required: Flammable liquid, toxic
Marine Pollutant: Not listed as marine pollutant, but notify carrier
Special Transport Precautions: Segregate from foodstuffs and strong oxidizers, ensure containers are upright and secure, emergency kits required on vehicles
Transport Codes: ADR/RID, IMDG, IATA all classify as flammable liquid; requirements for ventilation, no smoking, sign posting must be followed
Other Notes: Notify emergency response before transport in bulk, update shipping documents with emergency contact information
OSHA: Considered hazardous under Hazard Communication Standard (29 CFR 1910.1200), must be included in chemical inventories
TSCA: Listed on the Toxic Substances Control Act inventory
SARA Title III: Subject to reporting under SARA 302 (extremely hazardous substances), SARA 311/312 (acute health, fire hazard), may trigger SARA 313 (toxic chemical release reporting)
State Regulations: Listed under California Proposition 65, subject to state worker and environmental safety acts
WHMIS (Canada): Classified as B2 (flammable liquid), D1B (toxic), D2B (irritant)
REACH (Europe): Registered, subject to restrictions and safety assessments
Other Agency Findings: Not regulated as a carcinogen, but all releases and uses subject to local, regional, and federal inspection
Labelling: Requires Globally Harmonized System (GHS) labelling, SDS availability, training for users, periodic review of safety practices, and annual inventory reports
