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Product Name: Isopropyl Isovalerate
Chemical Name: Propanoic acid, 3-methyl-, 1-methylethyl ester
CAS Number: 4199-60-4
Recommended Uses: Cosmetic ingredient, skin conditioning agent, solvent
Supplier Details: Contact details for manufacturer or distributor, emergency phone number, and address
Classification: Flammable liquid, Category 3 (GHS)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor. May cause eye and skin irritation. Inhalation of vapors may cause respiratory discomfort.
Pictogram: Flame, exclamation mark (GHS07, GHS02)
Precautionary Statements: Keep away from ignition sources. Wear suitable protection. Use in well-ventilated areas. Wash hands thoroughly after handling.
Other Hazards: Can form explosive mixtures with air. Prolonged contact may lead to dermatitis.
Chemical: Isopropyl Isovalerate
Synonyms: 3-Methylbutanoic acid isopropyl ester
CAS No.: 4199-60-4
EC No.: 224-090-8
Concentration: 98-100%
Impurities: Trace esters of isovaleric acid, trace isopropanol
Inhalation: Move affected person to fresh air. Loosen tight clothing. Seek medical attention if symptoms persist or breathing becomes difficult.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water. Seek medical advice if irritation develops.
Eye Contact: Rinse cautiously with water for several minutes, lifting eyelids. Remove contact lenses if present. Continue rinsing. Get medical help if irritation occurs.
Ingestion: Rinse mouth. Do not induce vomiting. Get immediate medical advice. Provide symptomatic support.
Most Important Symptoms: Irritation, redness on skin or eyes, headache, dizziness from inhalation.
Advice for Doctors: Symptomatic treatment and supportive care as required.
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam.
Unsuitable Extinguishing Media: Direct water jet.
Specific Hazards: Vapors may travel and ignite at distant points. Fire may produce toxic fumes including carbon oxides.
Special Fire Fighting Precautions: Wear full protective gear and self-contained breathing apparatus.
Firefighting Instructions: Move containers from fire area if possible. Cool exposed containers with water spray.
Explosion Hazard: Containers may explode under fire conditions due to vapor pressure buildup.
Personal Precautions: Evacuate unnecessary personnel. Use personal protective equipment. Prevent inhalation of vapors.
Environmental Precautions: Prevent product from entering drains, surface water or soil.
Containment Methods: Stop leak if safe to do so. Dike spilled material.
Clean-Up Procedures: Absorb spill with inert material like sand, earth, or vermiculite. Shovel into a suitable container for disposal. Ventilate area.
Disposal: Follow disposal regulations for industrial chemicals. Avoid contaminating groundwater.
Handling: Ground and bond containers to prevent static discharge. Use spark-proof tools and explosion-proof equipment. Avoid direct contact with skin or eyes. Use in areas with local exhaust ventilation.
Hygiene Measures: Wash thoroughly after handling. Do not eat, drink, or smoke during use.
Storage: Store in tightly sealed containers in a cool, dry, and well-ventilated location, away from sources of ignition and incompatible materials.
Storage Conditions: Recommended storage temperature between 2°C and 8°C. Protect from sunlight.
Incompatibles: Strong oxidizers, acids, bases.
Engineering Controls: Local exhaust ventilation. Explosion-proof equipment for handling flammable vapors.
Exposure Limits: No specific workplace exposure limit values established for Isopropyl Isovalerate; adhere to general solvent exposure controls.
Personal Protective Equipment: Safety goggles, chemical-resistant gloves (nitrile or neoprene), lab coat or apron. Wear suitable respiratory protection if vapors are generated or ventilation is inadequate.
Environmental Controls: Minimize release to the environment. Use closed systems or discharge to a scrubber.
Workplace Monitoring: Check flammable vapor concentrations in work area, especially during transfer operations.
Appearance: Clear, colorless to pale yellow liquid
Odor: Pleasant, ester-like
Molecular Formula: C8H16O2
Molecular Weight: 144.21 g/mol
Melting Point: Data not available
Boiling Point: 180-190°C (approximate)
Flash Point: 78°C (closed cup)
Flammability: Flammable liquid
Density: 0.86-0.88 g/cm³ at 20°C
Solubility: Insoluble in water; soluble in organic solvents
Vapor Pressure: 0.2 mmHg at 20°C
Partition Coefficient (log Kow): Estimated 3.1
Autoignition Temperature: > 200°C
Evaporation Rate: Moderate, slower than acetone
Chemical Stability: Stable under normal conditions of use and storage.
Reactivity: Can react with strong oxidizers, strong acids, and bases.
Conditions to Avoid: Heat, sparks, open flames, sunlight.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, possible low-molecular-weight hydrocarbons
Polymerization: Not expected to occur under recommended conditions.
Incompatibilities: Avoid contact with strong oxidizing or reducing agents.
Acute Toxicity: Data on isopropyl isovalerate itself limited; structurally similar esters have low oral toxicity (LD50 rats > 2000 mg/kg).
Skin Irritation: May cause mild to moderate irritation with prolonged contact.
Eye Irritation: May cause redness or discomfort.
Respiratory Effects: High concentrations of vapors can cause dizziness, headache, or irritation.
Chronic Effects: Repeated or prolonged skin contact may cause dermatitis.
Carcinogenicity / Mutagenicity: No data available; not classified by IARC.
Sensitization: Not known to cause sensitization.
Routes of Exposure: Inhalation, dermal, ocular, ingestion.
Other Information: Low systemic toxicity anticipated for typical workplace exposures.
Ecotoxicity: Limited data; not expected to be highly toxic to aquatic life based on chemical structure.
Mobility in Soil: Low water solubility, likely to partition to organic matter.
Persistence and Degradability: Expected to be readily biodegradable under aerobic conditions.
Bioaccumulation Potential: Log Kow suggests some potential for bioaccumulation in aquatic organisms.
Other Adverse Effects: Unlikely to cause long-term environmental issues at low concentrations.
Regulatory Information for Environment: Controlled discharges recommended to avoid buildup in water bodies.
Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations.
Recommended Disposal: Burn in chemical incinerator equipped with afterburner and scrubber. For smaller quantities, absorb onto inert material and send to hazardous chemical disposal.
Packaging: Rinse containers three times before disposal. Puncture and collect containers for recycling.
Do Not: Pour into drains, water courses, or onto soil.
Sewage Disposal: Avoid release to wastewater systems.
UN Number: 1993
UN Proper Shipping Name: Flammable Liquid, n.o.s. (Contains Isopropyl Isovalerate)
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Labels: Flammable Liquid - 3
Marine Pollutant: No data indicates this classification.
Special Precautions for Transport: Keep containers tightly closed and upright. Use approved containers for flammable liquids. Keep away from heat and direct sunlight.
Regulations: IMDG, IATA, ADR guidelines apply.
Safety, Health, and Environmental Regulations: Product subject to regulation under chemical safety rules such as OSHA Chemical Hazard Communication, EU REACH, and GHS standards.
Inventory Status: Listed under TSCA (US), REACH (EU), DSL (Canada)
Labelling: Signal word “Warning”, hazard and precautionary statements as per GHS.
Restrictions: Not specifically regulated in cosmetics or food at the national level; users must check relevant local industry requirements.
Other Information: Safety data provided for information and risk assessment; users remain responsible for compliance with site, industry, and regulatory standards applicable to their operations.
