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Product Name: Isopropenylacetylene
Chemical Formula: C5H6
CAS Number: 563-45-1
Synonyms: 3-Methyl-1-butyne, Methylbutyne
Recommended Use: Industrial chemical, laboratory reagent
Supplier Details: Standard manufacturer address, emergency phone line provided through company safety department
Emergency Contact: 24-hour medical and fire service number for hazardous chemical response
GHS Classification: Flammable liquids Category 1, Acute toxicity (inhalation, dermal, oral) Category 4, Skin and eye irritant, Environmental hazard (aquatic)
Pictograms: Flame, Skull and Crossbones, Exclamation mark, Environment
Signal Word: Danger
Hazard Statements: Forms explosive mixtures with air, Toxic if inhaled or swallowed, Causes skin and eye irritation, May cause drowsiness or dizziness, Harmful to aquatic life
Precautionary Statements: Keep container tightly closed, Keep away from heat, sparks, open flames, Wear protective gloves and eye protection, Avoid breathing vapors, Wash hands thoroughly, Avoid release to environment
Route of Entry: Inhalation, skin contact, ingestion, eye contact
Target Organs: Respiratory system, skin, eyes, central nervous system
Chemical Name: Isopropenylacetylene
CAS Number: 563-45-1
Concentration: ≥ 98% by weight
Impurities: May contain trace amounts of residual solvents and byproducts depending on synthesis
Other Components: Non-hazardous solvents or stabilizers (only if used for storage)
Inhalation: Remove to fresh air immediately, keep victim calm, allow to rest in semi-upright position. Oxygen or CPR if breathing is difficult. Get medical attention.
Skin Contact: Take off all contaminated clothing. Rinse affected skin with plenty of water for at least 15 minutes. Seek prompt medical advice for burns or irritation.
Eye Contact: Rinse cautiously with water, lifting upper and lower eyelids occasionally for at least 15 minutes. Remove contact lenses if present and easy to do. Refer to ophthalmologist.
Ingestion: Do not induce vomiting. Rinse mouth with water only. Never give anything by mouth to an unconscious person. Call poison control center immediately.
Most Important Symptoms: Headache, dizziness, drowsiness, nausea, skin or eye burning
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray (trained fire fighters only)
Unsuitable Extinguishing Media: Direct water jet (may spread burning liquid)
Specific Hazards: Extremely flammable vapor may form explosive mixtures with air, vapors are heavier than air and may travel to distant ignition sources. Combustion produces carbon monoxide, carbon dioxide, and possibly toxic fumes.
Special Protective Equipment: Self-contained breathing apparatus and full protective gear needed for all personnel entering area.
Firefighting Procedures: Evacuate area, fight fire from safe distance, cool containers with water spray, avoid inhalation of combustion products
Personal Precautions: Shut off ignition sources. Evacuate non-essential personnel. Wear protective equipment—respirator, gloves, coveralls, goggles.
Environmental Precautions: Prevent spilled material from entering drains, watercourses, or sewers. Alert authorities if product enters environment.
Cleanup Methods: Absorb with inert material such as dry sand or earth—never use combustible material. Collect in labeled, closed containers for disposal. Ventilate area thoroughly.
Special Instructions: Do not touch leaking containers. Use only explosion-proof equipment. Remove all sources of ignition.
Handling Precautions: Use in well-ventilated area or fume hood, ground/bond all containers and equipment to avoid static discharge, avoid inhaling vapor, do not eat or drink in the working area.
Safe Storage: Store in tightly closed, properly labeled containers made of compatible materials. Keep in cool (<30°C), dry, well-ventilated chemical storeroom. Keep away from ignition sources, sunlight, oxidizers, acids, alkalis.
Incompatible Materials: Strong oxidizers, acids, halogens, peroxides
Storage Class: Flammable liquids (Class 1B)
Occupational Exposure Limit: No established OSHA, ACGIH exposure limits for Isopropenylacetylene; minimize exposure as with all volatile chemicals
Engineering Controls: Provide forced-air local ventilation, explosion-proof electrical fixtures, leak-proof chemical resistant flooring, emergency eyewash showers
Personal Protective Equipment: Suitable gloves (nitrile or neoprene), chemical splash goggles, flame-retardant labcoat or apron, chemical-resistant shoes
Respiratory Protection: Certified organic vapor respirators or positive-pressure supplied air for concentrations above recommended exposure or in confined spaces
Hygiene Measures: Wash hands, arms, face thoroughly after contact. Remove contaminated clothing and launder before reuse.
Appearance: Colorless to pale yellow liquid
Odor: Sharp, ether-like, slightly disagreeable
Odor Threshold: Not established
Molecular Weight: 66.10 g/mol
Boiling Point: 54 °C
Melting Point: -99 °C
Flash Point: -24 °C (closed cup)
Flammability: Highly flammable liquid and vapor
Vapor Pressure: 275 mm Hg at 20 °C
Vapor Density: 2.3 (air = 1)
Relative Density: 0.736 g/cm3 at 20 °C
Solubility: Low (water), miscible with organic solvents
Partition Coefficient (n-octanol/water): Not available
Auto-ignition Temperature: 345 °C
Decomposition Temperature: Not established
Evaporation Rate: Faster than water
Chemical Stability: Stable under recommended storage and handling conditions. Decomposes rapidly on heating or on contact with strong oxidizers.
Reactivity: Highly reactive to air, acids, bases, and strong oxidants. Polymerizes violently under certain conditions.
Hazardous Reactions: May form explosive peroxides, may react with halogens or strong acids to produce heat, pressure, toxic fumes
Conditions to Avoid: Heat, flame, sparks, direct sunlight, incompatible materials, static discharge
Hazardous Decomposition: Carbon monoxide, carbon dioxide, small quantities of irritating organic compounds
Acute Toxicity: Moderate toxicity by inhalation, skin contact, and ingestion; LD50 (oral, rat): approximately 120 mg/kg
Skin Corrosion/Irritation: May cause redness, irritation, possible dermatitis with prolonged exposure
Serious Eye Damage/Irritation: Severe burns, pain, watering, blurred vision
Respiratory Sensitisation: May trigger coughing, shortness of breath, headache
Carcinogenicity: Not evaluated by IARC, NTP, OSHA
Target Organ Effects: Central nervous system, liver, kidneys
Symptoms: Coughing, irritation, dizziness, drowsiness, muscle weakness, incoordination, unconsciousness at dangerously high exposure levels
Ecotoxicity: Harmful to aquatic organisms; may cause long-term adverse effects in aquatic environments
Persistence and Degradability: Readily biodegradable in air, less so in water and soil under some conditions
Bioaccumulation Potential: Not expected to bioaccumulate significantly due to rapid degradation
Mobility in Soil: High volatility, percolates rapidly through soil to groundwater
Other Adverse Effects: Can contribute to photochemical smog and ground-level ozone formation from atmospheric release
Disposal Methods: Incinerate in qualified, government-approved hazardous waste incinerator. Do not pour down the drain or discard with regular trash.
Contaminated Packaging: Empty containers and liners should be handled as hazardous waste and disposed through licensed chemical disposal contractor.
Special Instructions: Consult local, regional, and national competent authorities for regulations regarding disposal.
UN Number: 3295
Proper Shipping Name: Hydrocarbons, liquid, n.o.s. (contains Isopropenylacetylene)
Class: 3 (Flammable Liquid)
Packing Group: I (great danger)
Transport Labels: Flammable liquid
Special Precautions: Keep away from sources of ignition, ground containers during transfer, transport in tightly sealed containers, emergency response guidebook consult for incidents
Environmental Hazard: Marine pollutant
Labeling Regulations: Complies with OSHA Hazard Communication Standard 29 CFR 1910.1200, GHS globally harmonized standards
Chemical Inventory Status: Listed in TSCA (US), EINECS/ELINCS (EU), AICS (Australia), DSL (Canada)
Other Regulations: Subject to SARA Title III (Sections 302, 311/312), CERCLA (Comprehensive Environmental Response, Compensation and Liability Act), Clean Air Act requirements
Restrictions: Industrial and laboratory use only, not for food, drug, or household use
California Proposition 65: Not listed as a known carcinogen or reproductive hazard
