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Chemical Name: Isophthaloyl Chloride
Synonyms: Benzene-1,3-dicarbonyl dichloride
Molecular Formula: C8H4Cl2O2
Appearance: White to pale yellow crystalline solid
Typical Uses: Raw material in polymers and resins, especially in heat-resistant plastics, coatings, and fibers.
Classification: Highly corrosive, dangerous for inhalation, toxic if swallowed, severe skin and eye damage risk
Main Dangers: Fumes can burn airways, contact can burn skin or eyes, intense reaction with water
Signal Word: Danger
Symptoms: Burning sensation, coughing, shortness of breath, pain or blistering at contact sites, tearing, vision disturbance
Main Component: Isophthaloyl Chloride (C8H4Cl2O2)
Impurities: Trace acid chlorides, possible hydrochloric acid traces
Concentration: Typically above 98 percent active ingredient in commercial shipments
Inhalation: Move to fresh air, loosen tight clothing, get medical help fast, artificial respiration if breathing fails
Skin Contact: Remove contaminated clothing, wash skin vigorously with soap and water, call for emergency support
Eye Contact: Rinse with water for minutes, don't rub, call for emergency medical help immediately
Ingestion: Rinse mouth completely, never induce vomiting, seek clinic or hospital care without delay
Suitable Extinguishers: Dry chemical powder, carbon dioxide, foam rated for chemical fires
Hazardous Combustion Products: Toxic fumes including hydrogen chloride and phosgene gas
Fire Behavior: Vigorous reaction with water, creates corrosive vapors, intensifies fire if heated
Personal Protection: Wear chemical suit, self-contained breathing apparatus, minimize contact or direct exposure
Personal Protection: Chemical-resistant gloves, goggles, hooded suit, respirator
Spill Response: Isolate spill area, avoid water on spill, shovel up into dry containers, ventilate well
Environmental Caution: Do not flush into drains or water supplies, contain leaks with absorbent material suited for acid spills
Handling Advice: Work in a fume hood, avoid breathing dust or vapor, prevent skin or eye contact, use sealed containers and piping
Storage Requirements: Store cool and dry, away from water sources or humidity, separate from base chemicals and strong oxidizers
Container Materials: Use corrosion-resistant, airtight containers, check seals regularly for leakage
Ventilation: Strong local exhaust in work areas, closed system operation if possible
Personal Protective Equipment: Acid-resistant gloves, chemical suit, full-face respirator with acid gas filter, splash-proof goggles
Workplace Monitoring: Routine air sampling in processing areas, regular maintenance and inspection of protection equipment
State: Solid at standard room temperature
Color: Off-white, sometimes yellow tinge
Odor: Strong, pungent, acrid
Melting Point: 73–76 °C
Boiling Point: Decomposes before boiling
Solubility: Reacts with water, soluble in non-aqueous polar solvents
Vapor Pressure: Low at normal temperature, risk increases with heating
Chemical Stability: Stable under airtight, dry, cool storage
Reactivity Hazards: Immediate, vigorous reaction with water, alcohols, strong bases or oxidizers releases corrosive gases
Dangerous Byproducts: Hydrogen chloride gas, phosgene, other acid gases on contact with water or certain chemicals
Routes of Entry: Inhalation, skin absorption, ingestion, direct contact
Health Effects: Severe burns, respiratory distress, possible permanent lung damage, eye corrosion or blindness
LD50 (Acute Toxicity Estimates): Data from animal studies show toxicity at low milligram levels per kilogram, but variability based on species and exposure method
Chronic Effects: Repeated, low-level exposure can sensitize airway or induce chronic lung disease in some cases
Environmental Toxicity: Highly toxic to aquatic organisms, potential to acidify water on release
Persistence: Rapid breakdown in soil and water, but releases acid byproducts that continue to damage ecosystems
Bioaccumulation: Low—degrades quickly, but secondary effects from acidification are longer lasting
Waste Handling: Neutralize carefully with dilute base under controlled conditions, ensure all gas releases handled with scrubbers
Container Disposal: Avoid rinsing with water, decontaminate with approved neutralizing agents, send to hazardous waste facility
Regulatory Status: Classed as hazardous waste requiring documented treatment and tracking
Shipping Name: Toxic solid, organic, corrosive, n.o.s. (contains Isophthaloyl Chloride)
Transport Hazard Class: Corrosive and toxic materials
Packing Group: Group II or I depending on purity and quantity
Transport Guidelines: Label with corrosive and inhalation hazard warnings, secure containers tightly, avoid mixed loads with water-reactive materials
Workplace Limits: Exposure ceiling set by health agencies, usually parts-per-million low range due to acute hazard
Risk Phrases: Corrosive, toxic, hazardous to aquatic environments
Handling Controls: Subject to controls under chemical hazard, air quality, and environmental protection statutes
