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Cyclohexylisobutane: A Commentary

Historical Roots and Evolving Interest

Cyclohexylisobutane didn’t pop up overnight. Its story weaves through the push for new hydrocarbons in the mid-twentieth century, a period shaped by the chemical industry’s hunger for sturdy, adaptable compounds. Efforts in petrochemical refineries stood at the core of this development, pushing research beyond standard alkanes. Cyclohexyl-based hydrocarbons—like this one—emerged from those years of searching for building blocks that could handle tougher tasks in industries ranging from plastics to specialty solvents. Engineers working in post-war America and Europe often faced shortages, so the hunt for molecules that could step in for more expensive or volatile options was relentless. Cyclohexylisobutane, thanks to its blend of ring and branched structures, gave chemists a new tool for the kit.

Getting to Know the Stuff: Product and Properties

Cyclohexylisobutane stands as an organic compound straddling familiarity and subtle complexity. Structurally, it marries a six-membered ring—cyclohexyl—to an isobutane branch, forming a molecule that slips between straight alkanes and fully aromatic compounds. The result? A transparent, oily liquid, light enough to pour but hefty enough to hold its own where more volatile hydrocarbons break down. It smells faintly like mineral spirits. In physical terms, cyclohexylisobutane holds a boiling point above everyday gasoline ranges but below that of heavy oils, making it easier to separate, transport, and store than some of its class. Its density lands a bit above simple chain alkanes, reflecting that tight carbon ring. On the chemical side, the saturated nature gives it resistance to many oxidizing agents, but that same stability makes it harder to break down deliberately, so reactions tend to require a kick—heat, a catalyst, or both.

Preparing Cyclohexylisobutane: A Matter of Craft

Producing cyclohexylisobutane traces back to classic organic chemistry: a coupling of cyclohexyl and isobutyl groups, often through alkylation techniques. Early days saw attempts with Friedel-Crafts alkylation, pairing cyclohexane rings and isobutyl halides with aluminum chloride or similar Lewis acids as the catalyst. Anyone who’s worked an alkylation set-up knows it’s hardly a gentle process—acids can char glassware and leave sticky residues. Environmental concerns over traditional catalysts gave rise to new options, with zeolites or recycled alumina stepping up as greener alternatives. Purification relies on fractional distillation, depending on fine temperature controls and careful handling to separate this product from cousins with nearly matching boiling points. The result lands on the desk of chemical formulators looking for something sturdy, neutral, and dependable.

Labeling, Specs, and Nomenclature Nuances

Scientists who want to order or use cyclohexylisobutane may also see it listed as 1-cyclohexyl-2-methylpropane or, more rarely, cyclohexylisobutane. Naming conventions trip up even longtime chemists, especially since commercial catalogs sometimes lean into trade names. On a label, you’re likely to spot the molecular formula—C10H20—pointing to ten carbons, a full slate of hydrogens, and not a whiff of unsaturation. Handling the paperwork, you’ll see requirements for purity above 98% in specialty applications, mainly to avoid trace contaminants interfering downstream. Labels also lay out basic physical statistics, like boiling point and flash point, since those numbers guide everyone from process chemists to safety professionals.

Chemical Reactions and Tweaking the Structure

Many hydrocarbons welcome substitution reactions, and cyclohexylisobutane is no exception, though it holds a stubborn streak. Under heat and in the presence of bromine or chlorine, both ring and branch can accept halogenation, producing intermediates for other syntheses. Ring-opening reactions need more drastic conditions—think hefty catalysts or radical initiators—but offer access to linear derivatives prized in surfactants or lubricants. Hydrogenation isn’t really on the table given the molecule already sits fully saturated. Oxidation, outside extreme settings, runs slowly due to the compound’s resistance. Still, as new catalysts and selective functionalization methods emerge, researchers continue to try bending this molecule toward customized derivatives built for newer markets.

Safety and Getting the Job Done Right

Anyone used to handling liquid hydrocarbons knows there’s no excuse for carelessness, and cyclohexylisobutane demands the same vigilance. Its flash point sits higher than gasoline but not high enough for open flames or hot surfaces to be safe. It gives off vapors that can irritate skin, eyes, and lungs, prompting use of gloves, goggles, and fume hoods—precautions I’ve seen work time and again in industrial labs. Long-term exposure worries remain low compared to aromatic cousins like toluene, but proper ventilation still belongs in the workflow. Spills mean a call to the absorbent pads, and environmental release risks hassle from regulators. Good training and clear labeling matter more than ever, especially as new workers join seasoned hands on modern plant floors.

Uses: Finding Value Across Industries

Cyclohexylisobutane may not headline the world’s chemical catalogs, yet it has carved out its role in blending, specialty solvent formulations, and the slow expansion of niche plastics. Its stable nature makes it attractive where chemical resistance is critical, such as lubricant additives. Paint chemists look to it for thinning resins without risking yellowing or quick evaporation. Some researchers push its use in polymer processing, since the molecule’s bulky shape can change the flow and setting properties of emerging materials. Automotive and aerospace suppliers consider it as a base for cleaner-burning fuels and as a pathway to new lubricants. The market may seem limited at first glance, but history shows that a hydrocarbon like this often finds its true calling in the side-lines, supporting innovation rather than grabbing the spotlight.

What the Lab Churns Out: R&D Updates

Work continues in academic and industrial labs to squeeze more from cyclohexylisobutane. Catalysis teams aim to route its branch or ring toward more active derivatives, seeking new surfactant tail groups or stable solvent components immune to easy breakdown. Some environmental chemists hunt for biodegradation pathways, looking to harness soil microbes to clear up spills or persistent waste. Analytical chemists pay close attention to trace extraction and detection techniques, since the molecule can mask itself among similar hydrocarbon mixtures. Where my own experience comes in: troubleshooting detection when standard chromatography fails often reveals the importance—and the headache—of distinguishing cyclohexyl chains from simpler ones.

Risks to Health: A Realistic Perspective

Toxicity research on cyclohexylisobutane gives cautious comfort but throws up red flags where high doses or prolonged exposure crop up. Acute poisoning remains unlikely in day-to-day use, though nausea, headaches, or dizziness can kick in if vapor concentrations climb in small, unventilated spaces. Animal studies hint at mild irritation, but no alarming system-wide toxicity has shown up at doses short of outright negligence. Environmentally, the molecule’s structure slows biodegradation compared to lighter hydrocarbons, meaning accidental spills can linger. In my own view, low-to-moderate toxicity shouldn’t breed complacency; keeping containers sealed and systems closed ranks as smart practice, not just regulatory box-ticking.

The Road Ahead: What Cyclohexylisobutane Might Offer

Looking forward, cyclohexylisobutane stands at the intersection of endurance and adaptability. New manufacturing methods might make its preparation greener, reducing the waste streams that dogged earlier days. Emerging applications—such as high-performance lubricants designed for electric vehicles—could drive demand, as engineers re-examine the carbon bones of their materials. Regulatory pressures urge further research into environmental fate and human health impacts, reminding everyone that even time-tested hydrocarbons must answer for their risks and rewards. Scientists and industry folk willing to rethink old hydrocarbons often stumble on untapped uses, sparked by a molecule’s quiet resistance to breakdown, or its knack for dissolving stubborn resins without acting up under heat. The story of cyclohexylisobutane isn’t finished; as research deepens and applications expand, its value will depend on creative, responsible use backed by clear-eyed evaluation.




What is Cyclohexylisobutane used for?

A Glimpse Into Chemical Chores

Cyclohexylisobutane often slides under the radar. People rarely stop to think about chemicals by name, but plenty of products owe their existence to it. Fact is, it’s a colorless liquid that gives industries flexible options for creating, dissolving, and cleaning. Think of it as a kind of backstage worker—no fame, but always involved somewhere behind products we use.

Fuel Additives and Why They’re Not Boring

Fuel formulas seem far removed from daily talk. Still, every drop going into engines matters. Cyclohexylisobutane acts as a blending ingredient in gasoline, especially in parts of the world where knock resistance means less engine wear and fewer repairs. Gas blends with this compound reduce pounding inside engines, keeping everything running smoother for longer. Better performance for engines leads to longer machine life and, in some cases, better miles per gallon.

Solvents in Manufacturing

Paints, coatings, and adhesives need solvents that evaporate at predictable speeds. Cyclohexylisobutane checks that box and more. Workers prefer its relatively low odor, which means safer, more tolerable hours on the job. I’ve walked shop floors where bad fumes force constant mask use—chemicals like this cut those risks, which matters more than people realize. That small comfort opens the door for better workplace safety and morale, besides allowing projects to finish on schedule.

Cosmetics and Household Products

Consumers don’t always connect makeup and nail polish with chemistry, but smooth application and fast drying depend on the right solvent mix. Manufacturers use cyclohexylisobutane in nail polish removers and specialty perfumes. Its quick evaporation and mild scent keep products pleasant and simple to use. Keeping harsh chemicals out of bathrooms isn’t just a smart choice; it gives customers peace of mind without sacrificing effectiveness.

Greener Options and Safety Concerns

No one can pretend that chemical compounds come without baggage. Cyclohexylisobutane’s flammability and possible environmental impact demand attention. Research groups and regulatory agencies weigh in about safe uses, pushing companies to keep levels in air and water as low as possible. Even though the chemical earns points for lower toxicity than some older alternatives, long-term impacts can’t be brushed aside. In my work with environmental teams, conversations always circle back to minimizing exposure and improving disposal procedures.

Improving Safety and Saving Energy

Companies focus on closed-loop systems, careful ventilation, and shift schedules that limit direct exposure. Personal protective equipment helps, but it takes engineering controls for real peace of mind. When cyclohexylisobutane shows up in new coatings or tire sealants, energy use drops in manufacturing plants because of faster drying times and lower emissions. New generations of chemical engineers look for these efficiencies as part of broader industry changes—cutting costs and pollution at the same time.

Role in Research and Future Development

No single chemical solves every problem. Cyclohexylisobutane earns attention in research labs looking for safer alternatives to more hazardous solvents. As companies update formulas to comply with changing regulations, this compound often slips in to replace options flagged as higher risk. The challenge lies in balancing benefits with health and environmental responsibility—a conversation that moves fast as new data comes out.

What is the chemical formula of Cyclohexylisobutane?

Building Blocks: What Cyclohexylisobutane Tells Us

Chemistry holds incredible value for anyone curious enough to look. Underneath every common solvent, fuel additive, or pharmaceutical compound, structured formulas carry the story. Cyclohexylisobutane isn’t on grocery shelves, but understanding its chemical formula shows how small details produce big impacts in both industry and daily life. Cyclohexylisobutane combines a cyclohexyl group with isobutane. It’s not just a mouthful of a name—it’s C10H20. That formula points directly to its composition: ten carbon atoms, twenty hydrogens. At first glance, someone might think: it’s just another hydrocarbon. But take those carbon atoms, arrange them in a six-membered cyclohexane ring, attach an isobutyl group, and the resulting molecule paints a completely different picture.

Why Composition Matters

People sometimes overlook hydrocarbons unless they’re talking about gasoline or plastic bags. But unique hydrocarbons like cyclohexylisobutane matter for a reason. Their structural quirks place them at a crossroads between simple alkanes and specialty solvents. Each tweak—each ring, each extra carbon branch—shapes not just boiling and melting points, but also how these compounds dissolve, interact, and influence performance in everything from adhesives to fuel mixtures.

I remember sitting in a university lab and smelling the hexane we worked with. Cyclohexyl derivatives felt like a whole different beast: slightly less volatile, less of that stabbing gasoline odor. My professor pointed out that those structural ring formations tend to produce a bit more stability and less evaporation compared to straight or branched chains like isobutane. So, beyond the chemical jargon, the structure means fewer emissions escaping, safer handling, and opportunities to develop greener alternatives, at least when compared to some lighter solvents.

Practical Implications of Knowing the Formula

Companies and researchers have to look past the page and consider real-world impact. The difference between cyclohexylisobutane and its close cousins could mean changes in fire risk, solubility for paints and coatings, or even how easily bugs or bacteria break down leftovers. For example, a straight-chain alkane fades quickly under sunlight, but ring structures can persist—sometimes benefitting stability, sometimes raising environmental flags if they don’t degrade easily.

Getting the formula right isn’t just homework—it’s the foundation for regulatory filings, safety data sheets, and responsible manufacturing. Knowing its composition gives downstream users the information to decide how much to store on-site, how to transport it, or whether it’s possible to swap in a less hazardous substitute.

Looking Ahead: Safer, Smarter Chemistry

Every molecule tells its own story. Cyclohexylisobutane’s formula, C10H20, invites more than memorization. With experience in labs and conversations with chemists, I’ve seen how understanding these details can seed innovations in product safety, waste reduction, and material performance. Encouraging research in alternatives—maybe tweaking the structure for better biodegradability or improved safety margins—lets the world move toward cleaner chemistry. Anyone working with or around chemicals, from industry professionals to students, earns a real benefit by keeping those details in mind.

Is Cyclohexylisobutane hazardous or toxic?

Understanding What We're Dealing With

Any mention of a chemical most folks haven’t heard of—cyclohexylisobutane—tends to raise eyebrows. The unfamiliar name sounds like something out of a lab, far removed from the home or office. But knowing whether it poses real danger matters. Safety isn't just for the factory floor. It’s often about the products and industries that eventually touch everyone’s life.

Chemists blend cyclohexylisobutane for its hydrocarbon properties. Think paint solvents, specialty lubricants, or the sort of fluids that keep machinery moving smoothly. The interest in this chemical comes partly from its low reactivity, which makes it attractive for blends. This also means most sources label it as “low acute toxicity.” That comes from published safety data sheets and studies on oral, inhalation, and dermal exposure. But those phrases alone don’t tell the whole story.

The Real Hazards Out There

Inhaling hydrocarbons, including cyclohexylisobutane, can irritate airways and sometimes depress the central nervous system at high exposures. The risk goes up for workers who handle the raw substance daily. Eyes and skin don’t take kindly to concentrated splashes either. It's less toxic than household solvents such as toluene, but that doesn't make it a free pass for careless handling. Factories often need good ventilation, gloves, and protective glasses. MSDS documents echo this advice.

There’s another part of the hazard story. Cyclohexylisobutane is classified as a “volatile organic compound,” or VOC. That means it can contribute to ground-level ozone if enough gets into the air. In cities, smog isn’t just an annoyance—it tangles up with real health problems. VOCs from all sorts of sources play a role in that. Regulations from agencies like the EPA enforce limits on these emissions. Responsible producers track, report, and reduce releases to keep in step with clean air acts.

Staying Informed and Reducing Risks

I remember learning the hard way about fumes in small spaces after a day spent in a poorly ventilated garage. Keeping a space well-aired made a huge difference with oil-based products. Anyone working with chemicals in the shop or lab knows the drill: read labels, trust the gloves, and leave the food and drinks elsewhere. Direct experience sharpens respect more than any warning label, but strong guidelines keep people out of trouble in the first place.

Mishandling chemicals, even low-toxicity ones, leads to avoidable accidents. Knowing proper storage matters. Sealing up containers, storing away from direct heat, and segregating from incompatible substances all make a safer workplace. Most fires linked to hydrocarbons trace back to someone skipping steps, overlooking a source of ignition, or leaving caps loose. Preventing that isn’t rocket science, but it calls for steady habits and clear communication among crews.

Looking Toward Better Answers

As new compounds inch into daily use, data gaps crop up. Long-term studies on substances like cyclohexylisobutane can lag behind commercial interest. Companies and regulators weigh health effects from repeat exposures, persistence in the environment, and possible breakdown products. Open access to this research really empowers everyone—whether they're on a factory floor or managing compliance for a small business. Clearer data means stronger choices for safety and less speculation about hidden risks.

The bottom line? Cyclohexylisobutane doesn’t set off alarms like some industrial chemicals. Still, it commands respect in any workplace. Smart handling, reliable data, and up-to-date safety standards are the keys to avoiding trouble today and tomorrow.

How should Cyclohexylisobutane be stored?

Getting Clear on the Risks

Cyclohexylisobutane doesn’t show up in the headlines much, but anyone who handles chemicals for a living knows how quickly things go sideways without everyday caution. I’ve spent my share of years in cramped chemical storage rooms, and I can tell you: it all starts with respect for what you’re working with. Cyclohexylisobutane easily slips into the flammable liquids category. That means it can ignite if temperatures climb or if sparks fly—not exactly something you want to find out by accident.

The Realities of Storage Facilities

In most chemical storerooms, space gets tight, and shortcuts look easy. I’ve watched folks stack drums close to heat sources just to clear a path. That kind of practice invites trouble. Cyclohexylisobutane belongs in a cool, shaded area, away from heaters, piping, and direct sunlight. The right spot stays under 30°C, and humidity remains low. Think about it: less heat means less vapor forming, less risk in case of a leak.

Ventilation isn’t Optional

A lot of people—especially those new to chemical work—overlook the air these fires need. But poor airflow just lets vapors build up. Not everyone has luxury warehouse space, so sometimes it takes a bit of creativity: high shelves, open racks, exhaust fans. What matters is moving air so fumes can’t collect. Without that, even a small spill can become a big nightmare.

No Room for Weak Containers

It happens more than you’d think: smaller labs reusing containers, or sealing caps with tape. Cyclohexylisobutane eats away at weaker plastics. If you can, stick with tightly sealed metal drums or HDPE containers graded for hydrocarbons. I once saw a slow leak from a thin plastic bottle—sticky and dangerous on floor tiles. Tough packaging means fewer emergencies later on.

Labels Actually Matter

More than once, I’ve walked into storerooms where bottles miss labels, or handwriting gets hard to read by the next month. Each time, I see risk multiply. Printed, rugged, legible labels—showing exact contents, hazard warnings, and emergency info—keep everyone a bit safer. They also save time if something goes wrong.

Fire Protection is a Lifesaver

Fires don’t wait for you to get your bearings. It’s not about paranoia—it’s about being able to grab an extinguisher that actually handles flammable liquids. Water isn’t enough; a foam or dry chemical extinguisher stands a real chance. I’ve been through enough drills to see muscle memory kick in when it counts. Regular checks matter as much as the equipment itself.

Spill Response Plans: More than Just Paperwork

None of us look forward to chemical spills, yet being ready changes the outcome. Having a spill kit is only the start. Training everyone, from interns to senior staff, to handle leaks or vapor releases shrinks the danger—fast absorption materials and clear exit plans help clear the space quickly and safely. Documenting regular training adds another layer of protection, meeting regulatory expectations and giving peace of mind.

Why It’s Worth the Trouble

It’s easy to get complacent when nothing’s gone wrong for a while, but Cyclohexylisobutane isn’t forgiving. The time and resources spent on proper storage pay off with fewer injuries, no ruined stock, and less legal trouble. Safe practices aren't just about following rules—they protect jobs, reputations, and lives.

What are the physical properties of Cyclohexylisobutane?

What Sets Cyclohexylisobutane Apart?

Cyclohexylisobutane belongs to a class of organic chemicals called alkylcycloalkanes. Its molecular backbone features a cyclohexane ring connected to an isobutyl group. This structure shapes how it performs in practical settings, especially in industries like specialty chemicals and certain synthetic lubricant fields. Getting a grip on its real-world behavior starts with its physical properties.

Appearance and State Under Normal Conditions

Cyclohexylisobutane comes as a clear, colorless liquid at room temperature. In my experience working around various hydrocarbons, substances like this tend to slip by unnoticed until you catch a whiff — and even then, simple alkanes stay fairly odorless. That keeps accidental exposures subtle unless vigilance stays sharp.

Boiling and Melting Points

This compound boils somewhere between 170°C and 175°C, sitting higher than straight-chain isobutane due to its bulkier ring. Heating it on a standard lab hotplate brings out that elevated threshold. Melting lands close to -80°C, so you’re looking at a substance that stays liquid in most common environments, even in an unheated warehouse in winter. From my own stints running high and low-temperature stability tests, the wide liquid range means fewer surprises from phase changes in actual use.

Density and Solubility

Density makes a chemical’s handling and shipping a lot more straightforward or complicated. For cyclohexylisobutane, you’ll see something just under 0.8 g/cm³ at 20°C. That keeps it floating slightly over water, but not foam-like, which often helps with spill cleanups and storage. You won't get it to mix with water — the two separate cleanly. It does, though, dissolve well in organic solvents like ether or hexane. This behavior pops up over and over in the lab and the plant, especially when prepping samples or cleaning up equipment.

Vapor Pressure and Volatility

Vapor pressure shows how much the compound wants to jump into the air. Cyclohexylisobutane sits at moderate vapor pressure at room temperature. In practice, letting a bottle sit open doesn’t make it vanish as fast as lighter alkanes, but it doesn’t linger forever either. A fume hood takes care of the rest, keeping the air clear. Staying aware of vapor pressure impacts storage strategies, exposure risks, and fire hazards — important in my own lab routines.

Practical Considerations and Solutions for Safe Handling

Flammability always sits right near the top of the checklist with hydrocarbons. Cyclohexylisobutane catches fire, with a flash point around 50°C. That puts it just within the “flammable liquid” rules in most regions. From fire extinguishers to grounded containers, controlling ignition sources becomes critical on job sites and in transit. Over the years, I’ve seen accidents drop dramatically when teams stay consistent about these basics.

This molecule resists reacting with acids, bases, and most other mild chemicals, which means you’re dealing with a predictable, stable chemical. That stability feels like a relief for anyone setting up bench-top experiments or process vessels, reducing what-ifs in day-to-day work.

Direct Uses and Industry Outlook

One of cyclohexylisobutane’s main draws is its low reactivity combined with its workable liquid state. These features make it valuable as a solvent or building block in chemical syntheses. While not as widely used as some traditional alkanes, industries appreciate its clean-burning nature and stability, which help limit unwanted byproducts during manufacturing.

Using closed-system handling, regular training on flammable liquids, and proper labeling top the list of risk control strategies. Strong chemical safety protocols lower the odds of spillages or fire, proven by lower incident rates at sites that take those steps.

Cyclohexylisobutane
Cyclohexylisobutane
Cyclohexylisobutane
Names
Preferred IUPAC name 1-(Cyclohexyl)-2-methylpropane
Other names 1-Cyclohexyl-2-methylpropane
Isobutylcyclohexane
Pronunciation /ˌsaɪ.kloʊˌhɛks.ɪl.aɪ.soʊˈbjuː.teɪn/
Identifiers
CAS Number 13331-79-0
3D model (JSmol) `/data/mol*jsmol/Cyclohexylisobutane.sdf`
Beilstein Reference 1721394
ChEBI CHEBI:136602
ChEMBL CHEMBL3185107
ChemSpider 7798667
DrugBank DB16674
ECHA InfoCard 100.202.829
EC Number 204-698-0
Gmelin Reference Graefenberg [1828] Gmelin 1877 (4) 397
KEGG C19848
MeSH D029457
PubChem CID 12316744
RTECS number GU8575000
UNII 2V0583F76Z
UN number UN3295
CompTox Dashboard (EPA) DTXSID70804234
Properties
Chemical formula C10H20
Molar mass 140.27 g/mol
Appearance Colorless liquid
Odor Odorless
Density 0.824 g/mL at 25 °C (lit.)
Solubility in water Insoluble in water
log P 2.9
Vapor pressure 0.41 kPa (at 25°C)
Acidity (pKa) The acidity (pKa) of cyclohexylisobutane is approximately 50.
Magnetic susceptibility (χ) -8.72 × 10⁻⁶
Refractive index (nD) 1.447
Viscosity 1.31 cP (25°C)
Dipole moment 0.13 D
Thermochemistry
Std molar entropy (S⦵298) 437.7 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -245.3 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -6806.2 kJ/mol
Pharmacology
ATC code Not assigned
Hazards
GHS labelling GHS02, GHS07
Pictograms GHS02,GHS07
Signal word Warning
Hazard statements H225, H304, H315, H336, H411
Precautionary statements Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of water.
NFPA 704 (fire diamond) 2-3-0
Flash point 52 °C
Autoignition temperature 245 °C
Explosive limits Explosive limits of cyclohexylisobutane: 1.0–8.1% (in air)
Lethal dose or concentration LD50 (oral, rat): > 5000 mg/kg
LD50 (median dose) LD50 (median dose): 5000 mg/kg (rat, oral)
NIOSH NA7176
PEL (Permissible) PEL (Permissible Exposure Limit) for Cyclohexylisobutane: Not established
REL (Recommended) 200 ppm
Related compounds
Related compounds Cyclohexylmethane
Isobutane
Cyclohexane
tert-Butylcyclohexane