© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Work on Iprodione kicked off in the 1970s, fuelled by rising concerns over persistent crop diseases. Farms in Europe and North America were seeing fungal outbreaks that wouldn’t budge with older pesticides. Researchers aimed to find a molecule that could fight molds and offer more precise control with fewer environmental repercussions than some older broad-spectrum protectants. Through years of chemical tweaking and field trials, the dicarboximide structure of Iprodione showed real promise against pathogens like Botrytis cinerea. By the 1980s, regulatory approval followed across the US, Australia, and large parts of Asia for use in food production, especially for fruits and vegetables. The active ingredient’s market success mirrored a global shift toward targeted fungicides with shorter environmental half-lives. Companies and farmers quickly caught on, reshaping disease management in grapes, lettuce, and ornamentals.
Iprodione acts as a non-systemic, contact fungicide with a knack for halting spore germination and fungal growth on plant surfaces. Growers saw real benefits in reduced crop losses, and the chemical’s low phytotoxicity meant fewer worries about stunted growth or burns. Besides its action on Botrytis and similar fungi, Iprodione got picked for a wide swath of crops, from berries and tomatoes to turf and ornamentals. Product offerings range from wettable powders to suspension concentrates, with dosing guidelines fine-tuned over years of trial and real-world practice. Formulation scientists tapped its stable nature to package the substance in different forms to match farm equipment and application timing throughout a growing season.
This chemical stands out for its beige or grayish-white appearance, like fine flour. It brings a faint musty odor—nothing overpowering on a breezy day in the spray shed. Iprodione melts at about 133°C and holds up during typical storage in cool, dry places without rapid breakdown. It has poor solubility in water; just about 13 mg per liter dissolve at room temperature, but the material mixes with most common organic solvents. Farmers appreciate its persistence: even though UV light and weather gradually break it down, a scheduled spray program will keep disease at bay. The molecule stays mainly on the leaf surface, resisting plant uptake and rain wash-off, making it a favorite for protective coverage.
Most commercial Iprodione carries a technical grade content above 97%, with impurities such as related dicarboximides and trace solvents kept under tight control to pass regulatory muster. Labels lay out clear mixing instructions: heavy-duty gloves, closed mixing systems, and strict avoidance of skin or eye contact. Package information always spells out re-entry intervals, no-spray zones near water bodies, and vehicle cleanout directions. Over the years, regulators clamped down on claims, demanding data-backed intervals before harvest and direct cautions for environmental hazards, especially to aquatic life. Companies post regular bulletins with reminders about drift, runoff, and proper disposal.
Synthesis relies on reactions between substituted anilines and anhydrides, bringing together the right substituents onto a dicarboximide backbone. In the lab, acylation steps follow, using controlled temperatures and acid chlorides as activating agents. Yields depend on careful pH control and purification—separation of the crude material from excess reagents and byproducts through aqueous washes, followed by drying and crystallization. After that, packaging fills out the process, ensuring the final formulation hits target performance and purity thresholds for farm and turf use.
On the molecular scale, Iprodione holds up to moderate heat and mild acids but breaks down with strong alkalis and UV light. In the environment, the molecule slowly cleaves to release 3,5-dichloroaniline, a compound watchdog groups have flagged for possible health and ecological risks. Agrichemical companies have tried modifying its structure to boost efficacy and reduce runoff, with varying degrees of success. Lab teams explored analogues seeking greater selectivity or breakdown to less persistent metabolites, balancing disease control with safety. The dicarboximide core, though, anchors all these developments, remaining the mainstay of product action.
Growers and dealers know Iprodione under names like Rovral, Chipco, and Verisan on shelves across different continents. Each brand markets the active ingredient in various formulations, yet refers back to the same core molecule. Sometimes the code numbers RD-143, or technical-grade references, crop up in industry bulletins. The chemical’s unique structure—3-(3,5-dichlorophenyl)-N-isopropyl-2,4-dioxoimidazolidine-1-carboxamide—anchors its spot on regulatory registries and procurement sheets.
Mixing and applying Iprodione calls for a steady hand and respect for safety. Training focuses on good handling practice: wearing nitrile gloves, using splash goggles, and spraying in well-ventilated spots. Direct exposure, though unlikely with newer closed-transfer systems, brings skin and eye irritation concerns, pushing management to enforce personal protective equipment rules. Agencies have capped residue tolerances—a move that helps safeguard consumers and builds confidence in export of sprayed harvests. Worker safety extends through spill response drills and wash facilities at spray sheds, integral pieces of farm compliance programs. Community organizers keep a weather eye on water monitoring data, ensuring neither runoff nor drift threatens local streams or reservoirs.
Fruits and vegetables top the charts for Iprodione use, with grape vines, lettuce, berries, and brassicas long benefiting from targeted protection. Golf courses and professional sports fields call on it to keep turf healthy under heavy wear and rain. Ornamental growers in greenhouses favor it for bulb, stem, and petal diseases that can devastate value quickly. Over the last decade, some regions phased out its use on cereals due to residue management and crop rotation pressures, but horticultural and specialty crop markets remain strongholds for the molecule’s disease-fighting performance.
University teams and manufacturer labs have devoted years to study resistance trends, sprayer calibration, and environmental fate of Iprodione. Emerging resistance in Botrytis populations pushes researchers to keep tabs on spore samples and promote rotation with unrelated fungicide classes. Newer research hinges on spray droplet size and adjuvant selection, seeking to optimize coverage and minimize off-target movement. Researchers conduct fate studies tracing breakdown products in soil, gauging how rain and temperature swing the balance between efficacy and persistence.
Scientists don’t shy away from pointing fingers at potential downsides. Chronic animal studies found impacts on liver and possible links to cancer pathways, prompting tighter regulatory reviews and special attention from watchdog groups. The chemical’s limited uptake in plants reduces residue risk, but repeated exposure for workers and aquatic life stays front and center in policy debates. Toxicologists pressed for mandatory buffer strips along streams and rigorous monitoring of possible drinking water impacts. With each finding, policymakers balance food safety, farmer livelihoods, and rural community health.
Tomorrow’s use of Iprodione hinges on two big levers: regulatory patience and resistance management. Calls grow louder across the world to phase out persistent chemicals, yet growers still face fungal threats that can gut yields fast. Research may uncover ways to tweak the molecule, shave off risk, and extend its shelf life in integrated pest management programs. Next-generation biocontrol agents and precision-spray robotics may someday take over, reducing the routine need for chemical fungicides. For now, staying smart about timing, formulation choice, and field stewardship keeps Iprodione in the toolbox, even as the drumbeat for green chemistry keeps getting louder.
Iprodione matters a lot if you care about the health of plants and the struggles growers face. This chemical gets a lot of conversation in fields and gardens across the world. People with dirty hands and weathered faces rely on it for a reason—crop diseases can crush entire seasons of work, wrecking livelihoods overnight.
Iprodione shows up in fungicides used in agriculture, especially where rot, decay, and leaf spots punch holes in a farmer’s wallet. It’s a dicarboximide fungicide, which sounds technical, but the meaning is simple: this stuff tackles certain types of fungi before they take over. I’ve spoken to grape farmers who say bunch rot used to cost them almost everything before fungicides with iprodione gave them a fighting chance.
Ask golf course keepers about patchy turf and they’ll nod knowingly. Turf managers trust iprodione to hold off dollar spot, brown patch, and other turf diseases. Walk through a greenhouse in spring and you can sometimes spot bottles with iprodione listed on the label—tomatoes, beans, lettuce, and ornamentals all benefit from prevention and early treatment.
Grape growers, carrot producers, and even folks managing large fields of potatoes use this compound to keep diseases like botrytis, sclerotinia, and alternaria in check. Where winters are wet and spring comes late, fungal problems explode. Iprodione intervenes where crop rotation alone cannot keep problems away.
With something this helpful, you’d expect an easy road. That doesn’t match reality. Iprodione has raised serious concerns for decades. Studies flagged it as a possible carcinogen, and worries also focus on impacts to groundwater. A lot of tough conversations happen in farming communities and regulatory offices, because chemicals in the soil stick around longer than anyone would like.
People value clean water and safe food. I’ve listened to friends who won’t eat produce unless they know chemicals like iprodione have been used responsibly and in small amounts. Using more than recommended, or at the wrong times, risks contaminating more than just the plant—it can drift into streams and affect wildlife. That’s a heavy weight on honest growers trying to feed us.
Farmers don’t want to depend on expensive chemicals for every crop. Most are eager for alternatives. Integrated pest management offers real hope: more crop rotation, better drainage, time-tested disease-resistant varieties, and bio-fungicides. Universities run field trials that swap out heavy chemical treatments for a mix of prevention strategies, letting the soil breathe a bit more in between.
Nobody gets excited about new paperwork and limits on what works in the field—but rules forcing safer storage, more careful application, and lower allowed residues all push growers to reconsider habits learned over generations. My own experience with homegrown vegetables reminds me that a healthy mix of caution, science, and hands-on observation often wins out over shortcuts.
Iprodione still has a place in agriculture, especially during tough seasons. As better options become real and trustworthy, the whole industry can lean more on balance than brute chemical force. Real sustainability always grows from honest conversations, grounded in science, and respect for the people and earth we all depend on.
Iprodione is a fungicide—you’ll spot it on farms, sports turf, and even in greenhouses. It gets sprayed on crops like lettuce, carrots, onions, beans, and grapes to stop mold and rot in their tracks. Many growers counted on it for decades because it worked. I’ve seen farmers lean on these chemicals during seasons when disease pressure is relentless. They worry about losing a year’s income, so something like Iprodione often seems like insurance.
Looking through published studies, Iprodione isn’t a household name, but its health story deserves attention. It can bother skin or eyes on contact. Breathing in the dust or spray causes irritation. Long-term effects are the real worry. Animal tests show that large, repeated doses sometimes cause reproductive problems, and raise cancer risk. The U.S. Environmental Protection Agency classified it as a possible human carcinogen based on these findings.
Humans picking, packing, or spraying Iprodione get the most exposure. Farmworkers need gloves, masks, coveralls, and plenty of training. Most urban folks or casual gardeners won’t come close to this risk. Traces sometimes show up on veggies at grocery stores, but residue limits keep those numbers low. Still, watchdogs like the European Food Safety Authority keep reviewing new studies. In 2017, the EU decided to pull Iprodione from the approved list after spotting gaps in its safety data. They didn’t like the cancer signals, and they thought breakdown products stuck around in soil and water too long.
Cows, goats, and chickens aren’t usually fed feed sprayed with Iprodione, but they might graze nearby if run-off happens. Wildlife gets exposed when spray drifts or soil and water carry residues. Testing on rats, rabbits, and fish points to long-term harm at high doses. Bees and beneficial insects don’t always fare well either. With declining pollinator numbers, taking pesticide risks seriously feels urgent.
Pet poisoning cases pop up, usually if dogs chew on grass soon after fresh spraying. Symptoms include drooling, vomiting, and trouble walking. Vets suggest washing feet and seeking help fast. Households with kids or pets shouldn’t store these fungicides casually.
Research suggests safer options for controlling crop diseases. Integrated pest management brings together better plant spacing, drought-tolerant varieties, and organic compost to stop mold before it starts. Rotating fungicides also slows resistance. Switching to products with lower toxicity or relying on natural predators helps cut down chemical use overall.
Farmers are under pressure to deliver clean produce and protect their livelihoods. Regulators can improve safety by speeding up reviews of old pesticides, pulling those that raise questions, or limiting use near waterways. Grocery buyers can ask more about how food is grown and support farms investing in safer practices.
Iprodione’s safety depends on how and where it’s used. Living downwind of farms means experiences and risks might look different from office workers downtown. Staying curious, reading labels, and pushing for smarter farming often moves the needle more than waiting for a ban or sticking with the status quo.
Out in the field, real success depends as much on how something’s applied as the product itself. Iprodione brings a solid shield against fungal disease for everything from lettuce to beans, but it’s not set-and-forget. I’ve seen firsthand, both in my own backyard and while working alongside local growers, careful handling of this fungicide means healthier plants and better harvests—without risking resistance or food safety.
Fungal issues don’t show up at random. If the season brings extra rain or humidity, the risk goes up. Iprodione tackles botrytis and sclerotinia. From talking to researchers and following test plots, I’ve learned it works best when applied just before you expect infection—think of a field after a few damp nights. Spraying before you see big problems stops diseases at the gate.
Each crop tells its own story. Iprodione goes on at certain stages: for beans, right as pods set; for onions, just as bulbs swell. I make sure to study the label not as a legal safety net but as a guide written by folks who’ve tested hundreds of variables. Missing the window or spraying too often opens the door to resistant fungus. Following recommended intervals—usually 7 to 14 days apart—keeps you on the right track.
A lot rides on good mixing. Iprodione needs water and agitation. Lumps in the tank spell trouble, so take the time to mix thoroughly. My local extension agent showed me—slow, steady stir with good water pressure beats pouring powder straight in. Spray rigs or backpacks, it all works, but even coverage matters most. If you skip the undersides of leaves or let nozzles clog, you’ve wasted product and time.
Sun, clouds, and wind matter more than most folks reckon. If you spray and clouds break for a downpour, much of what you just sprayed goes into the soil instead of sticking to leaves. On windy days, product drifts into the ditch or your neighbor’s yard, putting money and safety at risk. I wait for calm early mornings or late afternoons. Applying during the cool part of the day keeps the spray where it should be and limits burn.
Iprodione belongs only on the plants that need it. Gloves, goggles, and a mask are bare essentials—my family’s health and my own depend on care. Cleaning up means rinsing tanks out in a way that doesn’t send runoff to ponds and streams. I follow the “no spray” buffer by ditches and gardens, since residue tails off fast but a little care up front protects pollinators and neighbors.
Disease cycles get outsmarted with rotation. Using the same tools season after season hands the upper hand to fungus, even the ones that don’t seem tough to start. Alternating with other fungicide classes every season keeps iprodione useful longer. I’ve joined grower groups and compared notes—rotating crops and carefully logging sprays slows down resistance, and it preserves soil health, too.
Smart use of iprodione draws on science, experience, and respect—for the land, our families, and the food we grow. When we take the time to get every step right, crops stay healthy and food keeps coming to our tables.
Iprodione earned a reputation as a useful fungicide. You’ll find it on vegetable plots, orchards, and even golf courses. People might not realize how many crops rely on its protection when dark spots and rot threaten entire harvests. Growers face uphill battles against fungi like Botrytis or Sclerotinia. In my experience walking fields with farmers, nobody wants to watch a bumper crop get ruined days before it’s ready.
Iprodione covers a lot of ground. Lettuce growers turn to it during cool, damp spring weather, a breeding time for lettuce drop and gray mold. Onions, carrots, and celery show similar vulnerability. Root crops need protection when the soil stays wet, making disease nearly impossible to contain through crop rotation alone.
Fruit crops count on Iprodione, too. Strawberry growers look for quick action against gray mold in particular. Grapes, plums, cherries, and peaches battle brown rot, which can wipe out fruit within days. If you ever watched fruit ripen in humid weather, you know one infected berry or plum can take out dozens nearby. Table grapes, destined for grocery shelves, lose their value if rot shows up on a single cluster.
Greenhouse vegetables may seem more sheltered from disease, but tomatoes, peppers, and ornamentals get their share of fungal threats. Growers work hard to balance prevention with safe produce. They want to keep their yields up and their compliance records clean.
It’s easy to forget sports turf and ornamental plants in this discussion. Golf course superintendents battle dollar spot and brown patch. Parks and nurseries treat cut flowers and bedding plants—often delicate, expensive to replace, and more likely to move across state lines. Spoiled plants cost time and money, and fungal spores don’t care whether you’re growing lettuce or landscaping snapdragons.
Chemical residues pop up at every talk about fungicides. Iprodione has residue guidelines that differ from crop to crop. For example, strawberries face stricter limits than carrots. That point matters. Nobody wants a child’s lunchbox turning into a chemistry experiment. Several studies have measured residue decay rates, showing that following recommended intervals keeps produce within safe limits. Farmers often rely on systems that track how long after the last spray before harvest, skipping treatments close to picking time to minimize risk. That’s a practical, boots-on-the-ground approach I’ve witnessed across continents.
Resistance runs as another concern. Overuse leads to fungal strains that laugh off what used to be reliable sprays. Many farm advisors encourage rotating Iprodione with chemicals from different classes or biological controls. That method works a lot like combination therapy in medicine—don’t give the fungi a chance to adapt.
Regulations on Iprodione shifted in places like Europe, largely out of health and environmental caution. Some suppliers scaled back availability. Farmers in those regions returned to old-school methods or accepted higher labor costs with hand or mechanical removal of rotten produce. Integrated management stands out as the future: smart timing, better airflow between plants, drip irrigation, and biological products can team up with fungicides to keep fields healthy.
Caring about which crops rely on Iprodione means understanding the tightrope walk farmers face. Every glass of juice, fruit bowl, or salad on the table carries the story of pests, weather, and safe use of crop protectants. We all share a part in the conversation—at the market, in policy, and by caring what goes into our food.
Iprodione has been a workhorse fungicide for many vegetable and fruit growers. Its ability to keep diseases like grey mold at bay in lettuce, grapes, and carrots creates real economic security on farms. Lots of farming families rely on a healthy harvest, so the idea of losing a crop to fungal outbreaks feels unbearable. Yet, the decision to use chemical fungicides never feels simple. I’ve worked around farming, and friends debate each season about that hazy line between managing crop loss and introducing potential problems into the ecosystem.
Regular use of Iprodione keeps fungal disease under control, but this can sow the seeds for resistance—fungi develop ways to shrug off the product. Over the years, that cycle gets harder for the farmer, leading to heavier chemical use or even loss of effective control. It’s not just the fungus in the field either. Research published by the European Food Safety Authority shows residue from Iprodione lingers on produce. Regulatory agencies have set limits, but the presence of residues can add anxiety for the health-conscious shopper, especially for families who worry about what lands in lunchboxes week by week.
Chemicals in soil rarely stay put. Iprodione breaks down, but its byproducts—especially 3,5-dichloroaniline—raise red flags. That compound sits on lists of water contaminants because it can slip into rivers and streams when fields drain after rain. Studies in places that rely on shallow wells have connected fungicide runoff to lowered water quality, making life difficult for both local wildlife and people who draw from those sources.
Beyond water, consider the community of life that keeps soil healthy. Earthworms, insects, and beneficial fungi pay the price if Iprodione overuse strips away organisms that keep the underground food web alive. Soils treated repeatedly with fungicides can lose their bounce—plant roots grow less vigorously, soil doesn’t absorb water as readily, and diverse life vanishes. The land’s long-term health can suffer, undermining future harvests and the resilience that small farms—especially organic ones—prize so highly.
Iprodione’s reach doesn’t end in the fields. Runoff makes its way into wetlands and ponds. The U.S. Environmental Protection Agency has marked amphibians and aquatic insects as groups that can take a hit. Tadpoles and frogs, already up against habitat loss, face bigger threats when water carries extra chemical loads. Not every downstream effect appears right away. Insects and small creatures may not vanish overnight but may grow fewer in number across seasons, taking out food for birds and other wildlife that depend on insect populations.
Big changes rarely come easy on farms, but there are ways to tip things back toward balance. Regulators in Europe and Australia have already moved to phase out or restrict Iprodione, which nudges growers toward better alternatives and more creative farming strategies. Rotating crops and fostering healthier soils often lowers disease risk in ways that don’t require constant chemical support. Biocontrols and disease-resistant seeds show promise—but only if growers get access to them without climbing through mountains of paperwork or spending twice as much on seed.
Results from California’s sustainable farms point to one lesson: local solutions shine brightest when communities, scientists, and public officials cooperate. Keeping food safe shouldn’t demand a trade-off with water and wildlife. Smart support for research and fair farm policies will help break the cycle of dependence on products like Iprodione.
| Names | |
| Preferred IUPAC name | 3-(3,5-dichlorophenyl)-N-(1,2-dihydro-3H-imidazol-4-yl)-2,4-dioxoimidazolidine-1-carboxamide |
| Other names |
Rovral Chipco26019 Rovral FLO C-2253 Bayer 29541 Sanfeno |
| Pronunciation | /ˌaɪ.proʊˈdaɪ.oʊn/ |
| Identifiers | |
| CAS Number | 36734-19-7 |
| Beilstein Reference | 80368 |
| ChEBI | CHEBI:34732 |
| ChEMBL | CHEMBL1389 |
| ChemSpider | 60859 |
| DrugBank | DB11979 |
| ECHA InfoCard | ECHA InfoCard: 100.102.011 |
| EC Number | 3.8.92 |
| Gmelin Reference | 87509 |
| KEGG | C06588 |
| MeSH | D010006 |
| PubChem CID | 37684 |
| RTECS number | NT1750000 |
| UNII | 6EQ4LB096X |
| UN number | UN3077 |
| Properties | |
| Chemical formula | C13H13Cl2N3O3 |
| Molar mass | 330.13 g/mol |
| Appearance | White powder |
| Odor | Odorless |
| Density | 1.32 g/cm³ |
| Solubility in water | 56 mg/L (20 °C) |
| log P | 2.90 |
| Vapor pressure | 2.7 × 10⁻⁷ mm Hg (25 °C) |
| Acidity (pKa) | 12.45 |
| Basicity (pKb) | 8.21 |
| Refractive index (nD) | 1.613 |
| Dipole moment | 4.02 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 610.3 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -460.5 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -475.7 kJ/mol |
| Pharmacology | |
| ATC code | D01AE17 |
| Hazards | |
| Main hazards | May cause cancer; suspected of damaging fertility or the unborn child; causes serious eye irritation; may cause respiratory irritation. |
| GHS labelling | GHS07, GHS09 |
| Pictograms | GHS07, GHS08, GHS09 |
| Signal word | Warning |
| Hazard statements | H302, H315, H317, H319, H351, H410 |
| Precautionary statements | Use personal protective equipment as required. Avoid release to the environment. Dispose of contents/container in accordance with local regulations. |
| NFPA 704 (fire diamond) | 2-1-1 |
| Flash point | > 201 °C |
| Autoignition temperature | 590 °C |
| Lethal dose or concentration | Oral rat LD₅₀: 3,500 mg/kg |
| LD50 (median dose) | LD50 (median dose): 3500 mg/kg |
| NIOSH | REL: 5 mg/m³ |
| PEL (Permissible) | 0.5 mg/kg |
| REL (Recommended) | 7 days |
| Related compounds | |
| Related compounds |
3,5-Dichloroaniline Procymidone Vinclozolin |
