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Product Name: Indoxacarb
Chemical Formula: C22H17ClF3N3O7
Common Synonyms: Steward, Avaunt
Recommended Uses: Insecticide used in agriculture for crop protection
Manufacturer Information: DuPont Crop Protection and other licensed agrochemical suppliers
Emergency Phone Numbers: Provided by local supplier, often a 24-hour service
UN Number: 2588 (for hazardous shipments)
CAS Number: 173584-44-6
Relevant Identifiers: EPA Registration Number printed on packaging
Prepared By: Safety departments within manufacturing organization
Hazard Class: Acute toxicity (oral, dermal), environmental hazard
Signal Word: Warning (on packaging and labels)
Hazard Statements: Harmful if swallowed, causes moderate eye irritation, very toxic to aquatic organisms
Pictograms: Exclamation mark, environment (dead fish/tree)
Precautionary Statements: Avoid release to the environment, wash thoroughly after handling, do not eat or drink while using
Potential Health Effects: May cause headaches, dizziness, gastrointestinal pain if ingested
Routes of Exposure: Inhalation, ingestion, skin contact
Target Organs: Central nervous system, liver (in rodents)
Active Ingredient: Indoxacarb Technical Grade
Concentration: 95% or higher (technical), 15-30% (formulated plant protection products)
Other Ingredients: Inert carriers, water, surfactants, spreaders, preservatives (in formulated products)
Impurities: Not intentionally added, but present in trace levels below regulatory limits
Chemical Family: Oxadiazine insecticide
Inhalation: Move to fresh air, observe for respiratory distress, seek medical advice if symptoms develop.
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, remove contact lenses.
Skin Contact: Remove contaminated clothing, wash skin thoroughly with water and mild soap.
Ingestion: Do not induce vomiting, rinse mouth, consult a doctor or poison control center immediately.
Most Important Symptoms: Nausea, vomiting, abdominal discomfort, mild respiratory symptoms.
Advice for Physicians: Symptomatic treatment, no specific antidote.
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray
Specific Hazards: Combustion produces toxic fumes including nitrogen oxides, hydrogen chloride, hydrogen fluoride
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective gear
Special Procedures: Prevent run-off to drains and waterways, keep containers cool with water spray
Explosion Hazard: Not classified as explosive, but dust can increase risk of ignition
Decomposition Products: Oxides of carbon, nitrogen, hydrogen chloride, hydrogen fluoride
Personal Precautions: Wear chemical-resistant gloves and goggles, avoid inhalation and skin contact
Environmental Precautions: Prevent uncontained product from entering watercourses, drains, or soil
Clean-up Method: Use absorbent materials such as sand or earth, collect residue in marked containers
Decontamination: Wash affected area with plenty of water, ventilate enclosed spaces
Waste Disposal: Dispose of through licensed chemical waste contractor in accordance with local regulations
Spill Reporting: Notify local environmental authorities in case of larger releases
Safe Handling Techniques: Avoid splashing, use only in well-ventilated areas, prevent dust formation in dry products
Suitable Storage Conditions: Store in original tightly closed packaging in a cool, dry, well-ventilated area
Temperature Limitations: Keep away from heat, sparks and open flames
Incompatible Materials: Strong oxidizing agents, alkaline substances
Hygiene Measures: Wash hands and arms before eating, drinking or smoking after handling
Occupational Exposure Limits: No workplace exposure limit set, use precautions recommended by product label
Engineering Controls: Local exhaust ventilation, eyewash stations in work areas
Respiratory Protection: Use NIOSH-approved respirators if dust or aerosol is generated
Skin Protection: Wear chemical-resistant gloves, long sleeves and trousers, wash exposed skin immediately
Eye/Face Protection: Safety goggles or face shield
Environmental Controls: Avoid surface water contamination, manage waste effluent responsibly
Appearance: Off-white to beige crystalline solid (pure technical), various forms in formulated products
Odor: Slight aromatic, not strong
Melting Point: 87–92 °C (technical grade)
Solubility: Slightly soluble in water, higher solubility in organic solvents
Density: Approximately 1.5 g/cm³ (pure active)
Vapor Pressure: Very low at room temperature (1.3 x 10⁻⁹ mm Hg at 25°C)
pH: 4–8 (1% solution as typically tested)
Flash Point: Not flammable as a solid
Stability: Stable in standard storage conditions
Chemical Stability: Stable under recommended use and storage conditions
Hazardous Reactions: None expected in normal conditions, avoid strong bases and oxidizers
Conditions to Avoid: Prolonged high temperature, exposure to direct sunlight
Hazardous Decomposition: Combustion generates toxic gases, as identified in fire section
Polymerization: Does not occur under standard use
Acute Toxicity: Oral LD50 in rats typically ranges from 200 to 500 mg/kg (moderate hazard)
Skin Irritation: Mild or no irritation in standard tests
Eye Irritation: Slight eye irritant based on animal data
Skin Sensitization: Not a known skin sensitizer
Chronic Toxicity: Animal studies suggest effects on liver and blood at high, long-term doses
Carcinogenicity: Not classified, no convincing evidence in animal studies
Mutagenicity: Tests did not show mutagenic potential
Reproductive Toxicity: No established risk at occupational exposure levels from available animal data
Toxicity to Fish: Highly toxic to many fish species (low LC50 values)
Toxicity to Aquatic Invertebrates: Extremely toxic to aquatic insects and crustaceans
Toxicity to Birds and Bees: Moderate to low acute toxicity to birds, low risk to pollinators under proper use
Environmental Fate: Low mobility in soil, rapidly binds to soil particles
Biodegradability: Slowly biodegradable
Bioaccumulation: Potential for bioaccumulation in aquatic organisms
Persistence and Degradation: Persistent under some environmental conditions, sunlight can speed break down
Disposal Practices: Triple rinse empty containers, puncture or crush before disposal
Container Disposal: Avoid reuse, recycle or incinerate only in licensed facilities
Waste Treatment: Do not pour residues into drains or water bodies
Incineration Conditions: Control temperature and emissions
Local Regulatory Compliance: Follow statutes regulating hazardous waste or pesticide waste
UN Number: 2588 (Toxic solid, organic, n.o.s.)
Proper Shipping Name: Indoxacarb formulation (if applicable)
Transport Hazard Class: 6.1 (toxic substances)
Packing Group: III
Marine Pollutant: Yes
Special Precautions: Avoid packages breaking or leaking, label as hazardous cargo
Air/Sea/Rail Transport: Subject to international dangerous goods regulations, check specific carrier rules
International Regulations: Listed with the US EPA, Canada PMRA, EU Plant Protection Product databases
OSHA Classification: Can be considered hazardous under Hazard Communication Standard
TSCA Status: Exempt for pesticide-specific formulations
WHMIS (Canada): D2B (toxic material causing other toxic effects – eye irritant)
REACH Registration (EU): Managed under crop protection regulations
Other Local Laws: Use permitted only by trained and certified applicators in many territories
Labeling Requirements: Follow national laws for hazard symbols, warning phrases, directions for use and safe disposal
Worker Protection Standard: Requires safety training, restricted reentry intervals after application, and controlled entry during application
