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Product Name: Indoline-2-Carboxylic Acid
Chemical Formula: C9H9NO2
Molecular Weight: 163.18 g/mol
CAS Number: 610-14-6
Synonyms: 2-Carboxyindoline, Indoline-2-carboxylate
Recommended Use: For research, laboratory chemicals, synthetic intermediates
Supplier Information: Manufacturer or distributor details, emergency contact numbers, address, website, email, and telephone support
Emergency Phone: Local poison control center or 24-hour emergency chem line
Classification: Not classified as hazardous under GHS criteria, precaution encouraged for all experimental chemicals
GHS Label Elements: No pictogram, signal word, or hazard statement mandated
Potential Health Effects: May cause irritation by inhalation, skin contact, or eye exposure; prolonged or repeated exposure increases risk
Environmental Hazards: Not expected to cause significant environmental impact in small quantities, vigilance needed due to limited data
Precautionary Statements: Avoid breathing dust or vapors, use only in well-ventilated spaces, minimize skin and eye contact, wash thoroughly after handling
Chemical Name: Indoline-2-Carboxylic Acid
Concentration: ≥98% (pure substance), trace impurities below 2%
Impurities: Typical laboratory grades contain minor related indole derivatives
CAS Number: 610-14-6
EC Number: 210-192-1
Inhalation: Move to fresh air; seek medical advice for any symptoms
Skin Contact: Wash immediately with soap and water; remove contaminated clothing; seek medical attention if irritation develops
Eye Contact: Rinse cautiously with water for at least 15 minutes; remove contact lenses if present and easy; get medical assistance
Ingestion: Rinse mouth with water; do not induce vomiting; get medical help if unwell; never give anything by mouth to an unconscious person
Most Important Symptoms: Irritation by contact; no acute toxicity data reported
Protection for First Aiders: Use gloves, mask, goggles; avoid direct contact with contaminated fluids or clothing
Suitable Extinguishing Media: Carbon dioxide, dry chemical, foam, water spray
Unsuitable Extinguishing Media: Direct water jets may spread spilled material
Specific Hazards: Combustion produces carbon oxides, nitrogen oxides, possible toxic vapors
Protective Equipment for Firefighters: Full protective gear, self-contained breathing apparatus (SCBA)
Fire Explosion Hazards: No known explosive hazards, avoid dust generation
Special Firefighting Procedures: Stay upwind, wear chemical-resistant clothing, prevent fire-fighting runoff from entering drains
Personal Precautions: Wear gloves, protective clothing, goggles, dust mask or particulate respirator
Environmental Precautions: Prevent release to the environment, avoid drainage into water bodies or soil
Clean-up Method: Sweep up spills gently; avoid raising dust; collect in suitable container for disposal; ventilate area
Decontamination: Wash spill site with water and mild detergent after material removal
Notification Procedures: Report large spills to environmental authorities as required
Handling: Use in a fume hood or well-ventilated area for pipetting or weighing; wear gloves and goggles; avoid inhaling dust or contact with skin and eyes; keep away from food or drink
Storage Conditions: Store in tightly sealed container, cool dry place, protect from light, away from incompatible substances such as strong acids, bases, oxidizing agents
Storage Temperature: Typically ambient, avoid extreme heat or cold
Incompatible Materials: Strong oxidizers, reducing agents, strong bases
Handling Precautions: Use appropriate containers; practice safe laboratory hygiene
Engineering Controls: Local exhaust ventilation, chemical fume hood, eye wash station, and safety shower in working area
Occupational Exposure Limits: No established exposure limit for indoline-2-carboxylic acid; use general dust limits as precaution
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile or neoprene), lab coat, safety goggles, dust mask (N95 or equivalent) for dusty handling
Hygiene Measures: Wash hands after handling, remove contaminated clothing, avoid eating or drinking in work area
Appearance: White to off-white crystalline powder
Odor: Odorless or faintly characteristic
pH: Not applicable (solid)
Melting Point: 222–226°C
Boiling Point: Data not available
Solubility: Slightly soluble in water, soluble in ethanol, and organic solvents
Vapor Pressure: Negligible at room temperature
Density: Approximate 1.3–1.4 g/cm³
Partition Coefficient (log Kow): Not determined
Flash Point: Not available
Autoignition Temperature: Not available
Decomposition Temperature: Data limited, avoid prolonged heating above melting point
Chemical Stability: Stable under normal laboratory conditions
Reactivity: Not reactive with water or ordinary atmospheric conditions
Conditions to Avoid: Excess heat, moisture, light exposure, incompatible chemicals
Incompatible Materials: Strong acids, strong bases, oxidizers, reducing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides
Hazardous Polymerization: No hazardous polymerization expected
Acute Toxicity: No data for oral, dermal, or inhalation routes; presumed low toxicity based on structure and related chemicals
Chronic Toxicity: No long-term studies found; avoid unnecessary exposure
Irritation: May cause irritation of skin, eyes, respiratory system on direct contact
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, or OSHA
Mutagenicity: No mutagenicity data available
Reproductive Effects: No data available, best practice to minimize exposure
Other Effects: Not expected to cause systemic toxicity in small laboratory quantities, avoid ingestion and repeated exposure
Toxicity: Data insufficient, not known to be acutely toxic to aquatic life
Persistence and Degradability: Not fully assessed; likely to persist in soil and water due to aromatic structure
Bioaccumulative Potential: Not established; structure indicates moderate potential
Mobility in Soil: Limited data, low volatility
Other Adverse Effects: Avoid release to the environment; follow standard containment practices
Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations; chemical waste containers for laboratory solvents and solids
Contaminated Packaging: Triple rinse and destroy or submit to chemical waste stream
Special Precautions: Do not dispose of in regular trash, down drains, or general laboratory waste; work with approval from waste management officer
Disposal Containers: Use labeled, sealed HDPE or glass waste bottles for solids
UN Number: Not regulated for transport
Proper Shipping Name: Chemical, N.O.S. (not otherwise specified)
Transport Hazard Class: Not classified as hazardous for air, sea, or land
Packing Group: Not applicable
Environmental Hazards: Not expected to present significant hazard during transport
Precaution During Transport: Securely package, ensure secondary containment, follow general good shipping practices
Inventory Status: Complies with TSCA (U.S.), DSL (Canada), REACH (EU) registries as a laboratory substance
Labeling Requirements: Not classified under GHS for hazard labeling
SARA Title III: Not listed or regulated
California Proposition 65: Not listed
Other Regulations: Meets requirements for laboratory research exemption in most jurisdictions; users must follow institutional and governmental safety protocols; review site HS&E and local environmental laws for chemical handling and reporting
