© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Immobilized Arginase
Chemical Family: Enzyme preparation immobilized on solid carrier
Manufacturer: Supplier contact information
Recommended Use: Biocatalysis, research applications, industrial processes
Synonyms: Arginase, L-arginine amidinohydrolase immobilized
Product Code: Relevant code from supplier
Emergency Telephone Number: 24-hour emergency contact
Email Address: Safety data inquiries
GHS Classification: Non-hazardous in standard conditions, mild respiratory sensitizer potential, low toxicity
Signal Word: None required
Pictograms: Not classified under GHS
Hazard Statements: Dust may cause mild transient irritation of eyes, skin, or respiratory tract
Precautionary Statements: Avoid dust formation, use protective equipment
Potential Health Effects: Direct contact with large amounts may trigger irritation, pre-existing respiratory conditions could worsen
Symptoms of Exposure: Redness, coughing, mild discomfort on contact, rare allergic reaction
Main Ingredient: L-arginase enzyme (CAS Number: 9000-96-8), typically 3-10% by weight
Carrier Material: Inert polymer or silica-based solid, deposit process varies by supplier
Preservative: Trace amounts of sodium azide or similar, less than 0.1%
Other Ingredients: Buffer salts, residual moisture
Impurities: Levels within acceptable laboratory and industrial use standards, not expected to change hazard classification
Inhalation: Remove victim to fresh air, seek medical advice if irritation or breathing difficulty continues
Skin Contact: Wash with plenty of soap and water, seek assistance if symptoms persist
Eye Contact: Rinse cautiously with water for at least 15 minutes, contact healthcare provider if irritation develops
Ingestion: Rinse mouth thoroughly, seek professional advice, avoid inducing vomiting unless directed by medical personnel
Medical Attention: Symptomatic treatment based on clinical assessment, sensitivity testing if allergic reaction suspected
Suitable Extinguishing Media: Water spray, CO2, dry chemical, foam
Unsuitable Media: Avoid direct high-pressure water jet on powder spills
Special Hazards: Thermal decomposition could release carbon oxides, nitrogen oxides, possibly vapors of carrier material
Protective Equipment for Firefighters: Full protective gear, self-contained breathing apparatus
Additional Information: Dust in air may form explosive mixtures in rare situations — fire control involves containing spread and limiting exposure to dust clouds
Personal Precautions: Wear approved respiratory protection if dust forms, use gloves and goggles
Environmental Precautions: Prevent spillage from entering streams, drains, or soil to avoid unintended ecological impact
Methods for Cleaning Up: Collect using non-sparking tools, shovel material into suitable containers for disposal, ventilate area, wash residue with water
Reference to Other Sections: Consult relevant sections for personal protection, handling, disposal, and ecological impact
Safe Handling: Minimize dust generation, handle using recommended PPE, work in areas with appropriate ventilation, avoid contact with skin or eyes, avoid inhalation
Storage Conditions: Store in tightly sealed containers at 2–8°C, keep away from heat, oxidizers, and moisture
Incompatibilities: Strong acids, bases, oxidizing agents, high temperatures degrade activity and may damage carrier matrix
Other Precautions: Label containers, maintain inventory logs, inform staff about enzyme and carrier material risks
Occupational Exposure Limits: No established limits for immobilized arginase, observe general enzyme dust threshold (<5 mg/m³ for respirable fraction)
Engineering Controls: Use local exhaust ventilation, fume hood, containment systems for powder
Personal Protective Equipment: Safety glasses, chemically resistant gloves, long-sleeved lab coat, NIOSH-approved dust mask or respirator when airborne particles form
Hygiene Measures: Wash hands thoroughly after handling, avoid eating or drinking in work area, remove contaminated clothing before breaks
Appearance: Fine, off-white to tan powder or granules, dependent on carrier material
Odor: Slight to none
pH (10% suspension): 6.5–8.0
Melting Point/Freezing Point: Not applicable (decomposes before melting)
Solubility in Water: Insoluble as solid, enzyme activity may be released upon contact with aqueous solution
Boiling Point: Not applicable
Flash Point: Not established
Vapor Pressure: Negligible
Density: 0.3–0.7 g/cm³ (bulk)
Other Properties: Stable under recommended storage, may clump if exposed to moisture
Chemical Stability: Stable under normal laboratory and storage conditions
Reactivity: No hazardous reactions in standard use, reacts strongly with oxidizing agents
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen compounds upon burning or high-temperature decomposition
Polymerization: Not known to polymerize
Conditions to Avoid: Prolonged exposure to moisture, high temperature, strong acids or bases
Potential Health Effects: Mild irritation possible after prolonged exposure, rare allergic sensitization to proteins
Acute Toxicity: Low oral and inhalation toxicity for both enzyme and carrier, LD50 not determined due to low hazard
Chronic Toxicity: No evidence of carcinogenicity, reproductive toxicity, or mutagenicity from current literature on immobilized enzymes
Routes of Exposure: Inhalation, skin and eye contact, accidental ingestion
Symptoms: Rash, itch, mild respiratory irritation, especially for atopic individuals
Aquatic Toxicity: Based on enzyme biochemistry, very low toxicity for aquatic organisms at expected dilutions
Degradability: Protein components degrade naturally, carrier matrix persistence matches typical inert solid-phase materials
Bioaccumulation: Not expected to bioaccumulate
Mobility: Immobilized enzyme unlikely to spread through soil or water except as particulate
Other Effects: High concentrations in confined ecosystems pose theoretical risk by physical smothering rather than chemical toxicity
Waste Treatment Methods: Collect unused or spilled material in labeled containers, follow local and national regulations for disposal of enzyme and carrier material
Incineration: Acceptable disposal route in permitted waste incinerators
Landfill: Small quantities, after deactivation, permitted by local regulation
Duty of Care: Avoid uncontrolled release, label disposal containers, consult waste management officials for additional requirements
Contaminated Packaging: Rinse and treat as chemical waste, avoid reuse for food or pharmaceutical storage
UN Number: Not regulated under ADR, IMDG, IATA
Proper Shipping Name: Non-hazardous research enzyme
Hazard Class: Not classified as dangerous goods
Packing Group: Not applicable
Special Precautions: Ship in sealed containers, control moisture, ship chilled for long journeys to preserve active enzyme
Transport Labeling: Ensure clear identification and safety labeling in transit
Labelling: Not subject to hazardous chemical labeling under GHS, OSHA, WHMIS or EU CLP
Inventory Status: Components listed in TSCA, EINECS, DSL and other major chemical inventories
Relevant Legislation: Complies with applicable safety, environmental, and workplace regulations for research and industrial enzymes
Other regulations: Not controlled as biotoxin, not scheduled in CWC or other restricted lists
Worker Training: Staff handling should receive training in safe management of biologically active ingredients
Reporting Requirements: None specific, ensure safety procedures and incident logs retained as standard laboratory or industrial practice
