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Hexaflumuron and Diflubenzuron: A Deep Dive into Modern Insect Growth Regulators

Historical Development

In the battle against crop-damaging insects and termites, Hexaflumuron and Diflubenzuron grew out of a need for a new kind of protection. Pests built resistance to common chemical sprays, so researchers started looking for a different angle by the late 1960s. Diflubenzuron, first registered in the United States in 1979, followed years of exploration into benzoylurea derivatives. These compounds showed they could stall the life cycle of insects, hitting them right at the molting stage, a point of real vulnerability. Hexaflumuron joined the family much later, quickly becoming a popular termiticide, prized for its ability to keep colonies from rebounding. The history of these two isn’t simply about chemistry — it’s a story of shifting focus from killing pests outright to disrupting their renewal and survival, reducing the pressure on broad ecology along the way.

Product Overview

Both products serve specific roles. Diflubenzuron, often labeled under names like Dimilin, targets caterpillars and beetles in crops and forest applications. Hexaflumuron, sometimes seen on termite bait systems, blocks insect development without the broad toxicity of older pesticides. Unlike many legacy chemicals, these compounds target chitin synthesis, undermining the armor insects need to grow. Farmers see healthier plants, termite control companies see real reductions in colony strength, and environmental regulators notice fewer risks to people and animals. As demand grows for smarter, safer crop and urban pest strategies, these products draw attention from a wide range of industries.

Physical & Chemical Properties

Hexaflumuron appears as a white crystalline powder, stable for long periods under normal conditions. Water solubility rates run low, so leaching into water supplies remains a minor concern in use. As a benzoylurea, it combines fluoroaromatic and trifluoromethyl phenyl structures, offering chemical toughness needed for outdoor applications. Diflubenzuron carries a similar white or off-white profile, less soluble than many organophosphates, with stability rooted in its own trifluoromethyl and urea bonds. Both compounds keep their shape under light and heat, which means they stay active longer in soils or bait stations. These characteristics — low vapor pressure, slow degradation, and targeted potency — have real meaning for users deciding which tools to trust.

Technical Specifications & Labeling

In the field, numbers matter. Registered diflubenzuron formulations usually range from 25% to 98% technical grade, with granular and wettable powder options for spreaders and aerial spraying. Labels stick close to legally defined limits: maximum annual application rates depend on crop, with withdrawal periods for edible produce. Hexaflumuron comes in termite bait cartridges, concentrations adjusted to the smallest fractions of a percent. Both list clear reentry intervals, shelf life expectations, PPE requirements, and storage instructions. Each country’s regulators set specific guidelines for maximum residue levels, bound by environmental standards and risk tolerance. The clarity on a label helps contractors, growers, and safety inspectors manage hazards and compliance.

Preparation Method

Scaling up production of these active ingredients demands tight process control. Diflubenzuron synthesis routes usually couple 4-chlorophenyl isocyanate with 2,6-difluorobenzamide in solvents under specific temperatures. Certification for each batch means high-purity output and no surprises in environmental release. Hexaflumuron draws on multistep routes involving fluorination, acylation, and coupling reactions, using intermediates that skilled chemists must handle precisely. Waste streams receive treatment according to hazardous waste laws, with strict record-keeping from the earliest step to final packaging. The facility’s level of automation — batch or continuous — makes or breaks the economics, but every operator knows the downstream impact of even minor slip-ups. Product quality stems from a marriage of robust process design and accountability at every link.

Chemical Reactions & Modifications

On the molecular level, both compounds take their power from interfering with chitin biosynthesis. That means blocking the conversion steps that insects rely on for proper exoskeleton formation. Chemists have explored changing side groups to raise activity against specific insect orders or blunt non-target impacts. Halogenation steps create distinct profiles for spectrum and degradation times, and these adjustments translate into serious competitive differences in the market. Research continues into creating derivatives with quicker environmental breakdown or reduced human exposure. Real progress demands a careful balance between stability for application and safe, controlled disappearance from fields or homes. Competitive pressures encourage innovation in formulation and application mode, so the chemistry doesn’t stand still for long.

Synonyms & Product Names

Market names can confuse the story for anyone outside the industry. Diflubenzuron, for example, shows up as Dimilin, Micromite, or Vigilant, each tied to different regions and crops. Hexaflumuron carries commercial brands like Sentricon and Recruit in termite control systems. Synonyms like N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide for diflubenzuron, or 1-(3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl)-3-(2,6-difluorobenzoyl)urea for hexaflumuron, fill chemical catalogs and regulatory filings, reinforcing the need for clear label reading and local translation.

Safety & Operational Standards

Safe handling starts with the basics. Both compounds need gloves, eye protection, long sleeves, and trained users who understand the product’s label. Diflubenzuron and hexaflumuron present low toxicity to humans at typical use rates, though dust or fine particles call for respiratory protection indoors. Spill containment equipment and emergency wash facilities belong wherever these powders or liquids get handled. Technicians adopt protocols for mixing, application, cleanup, and disposal, as regulators check that run-off doesn’t exceed limits for aquatic habitats. Workers need to know about low acute risk, but chronic exposure data keeps agencies looking for signs of long-term effects. Regular safety training makes all the difference: accidents drop, compliance jumps, and trust follows.

Application Area

On row crops and orchards, diflubenzuron works against insects that chew and molt, including gypsy moths, locusts, and cotton bollworms. Forestry programs in North America rely on aerial applications to blunt pest outbreaks in pine stands, reducing tree death and keeping wood vital for local industries. Hexaflumuron hits mainly termite colonies in buildings, schools, and critical infrastructure. Bait stations create a slow effect, letting worker insects carry active ingredients to the queen and larvae for a systemic kill. This shift from broad-spectrum spraying to pinpoint, slow-action baits keeps contact with children, pets, and wildlife at low levels. Both compounds also find use against mosquitoes in water bodies, though restrictions limit use where endangered species might be affected. People in agriculture and urban management want tools that solve real problems without trading one hazard for another, so these niche applications gain popularity wherever regulations allow.

Research & Development

The R&D engine behind these chemicals never rests. Resistance management drives much of the current inquiry. Lab studies look for early warning signs in pest populations that might survive sublethal exposure. Trials experiment with combination products, rotating active ingredients across seasons to reduce the chance of resistance genes building up. Chemists work on microencapsulated beads, gel suspensions, and “smart baits” that deploy in sync with pest peaks. Analytical teams study residue dynamics — how fast parent compounds break down and what, if any, byproducts linger in food or water. Fieldwork means plotting impact not only on target pests, but on beneficial insects, birds, and even soil microbes. The race to stay ahead of changing pests and new legal demands never slows, and progress regularly spills over into general pesticide science.

Toxicity Research

Concerns around safety push toxicology research year after year. Both diflubenzuron and hexaflumuron show low acute toxicity to people and animals by modern standards. The main worry focuses on aquatic life: diflubenzuron, for instance, can harm certain freshwater invertebrates when run-off leaves the sprayed area. Studies on chronic effects point to low cancer risks and limited potential for hormone disruption. Regulators in the EU, US, and Asia demand extensive reviews before renewal of registrations. Teams test breakdown products, making sure none trigger unexpected health impacts. Real-world use data, combined with laboratory modeling, help refine hazard maps and disaster response plans for spills or over-application. Transparency in reporting, plus sharing of adverse event databases, earns public trust that data isn’t hidden or selectively reported.

Future Prospects

Farmers want more than new chemicals; they look for integrated pest management tools that can pair with biological controls or digital monitoring systems. Energy costs, weather extremes, and changing trade rules add pressure to limit synthetic pesticide use and find lower-dose, smarter solutions. Researchers keep looking for formulations that do more with less, and companies invest in outreach and stewardship programs to keep these products working effectively long term. Upcoming regulation in Europe and California could push further advances, demanding faster degradation, more precise application, and expanded environmental monitoring. New application technologies — using drones, variable-rate sprayers, or precision baits — could help cut off resistance before it gets out of hand. What holds true in every setting is the importance of evidence, adaptability, and honest communication between industry, oversight agencies, and the communities who live beside field and forest.




What is Hexaflumuron / Diflubenzuron used for?

Understanding Their Purpose

Farmers and pest control experts know persistent bugs can wreck crops or forests or even harm public health. Hexaflumuron and Diflubenzuron hold a spot on the front lines of these battles. Both are classified as insect growth regulators. These compounds disrupt the normal development of insects. Without proper development, pests struggle to mature or reproduce—populations drop.

How They Work

Insects, such as termites, mosquitoes, caterpillars, and beetles, shed their outer skin as they grow; this is known as molting. Hexaflumuron and Diflubenzuron work by messing with how insects build their new exoskeletons after shedding the old ones. Without success in this process, growing insects die before adulthood. This targeted trick has made both chemicals popular in managing outbreaks that threaten forests, crops, or structures.

Common Use Cases

For decades, I've seen diflubenzuron sprayed in orchards and on public lands. Municipalities use it to control gypsy moths, forest tent caterpillars, and other pests that defoliate valuable trees. Ranchers and vineyard owners often turn to these chemicals to protect cash crops from relentless insects. In urban areas, pest control companies rely on hexaflumuron to manage termite colonies without dousing homes in broad-spectrum poisons. These applications can help slow the march of pesticide resistance compared to older, more aggressive chemicals.

Why Their Use Matters

Unchecked insect populations, especially invasive species, cost billions in crop losses worldwide. The US Department of Agriculture has estimated tree damage from gypsy moths at more than $30 million a year across several states. In my farming days, a single season's infestation could wipe out years of effort if smart controls hadn’t been used. By stopping insects where it hurts—during growth—these chemicals deliver results with less risk to pollinators or people than general-purpose pesticides.

Balancing Benefits and Risks

All pesticides raise safety questions. Science shows diflubenzuron breaks down with sunlight and soil microbes; that limits long-term buildup. Its selectivity means non-target creatures like bees, birds, or mammals are less likely to get a lethal dose. Still, nothing is perfectly benign. Overuse or poor timing can hurt aquatic insects and crustaceans when run-off finds streams. Hexaflumuron and similar products must be treated as tools—powerful, but not without side effects.

Looking to the Future

Modern agriculture and forestry call for solutions that protect crops and forests while also considering health and the environment. Researchers look for ways to combine targeted insect growth regulators with natural predators or biological controls, cutting down chemical use. Governments require impact evaluations and more precise guidance for when and how to spray. Companies sometimes reformulate the active ingredients to increase selectiveness or reduce drift. Wisely using such tools fits a larger shift toward sustainable food and land management—balancing results with responsibility.

What Informed Choice Looks Like

Sound pest management doesn’t mean ignoring hazards or giving up on helpful science. It means digging into research, talking to trusted experts, and watching site conditions. Hexaflumuron and Diflubenzuron offer proven, practical help when land, forests, or structures come under attack. In the right hands and with updated science, these products keep food on the table and landscapes healthy for everyone.

How does Hexaflumuron / Diflubenzuron work to control pests?

Better Than Guesswork: How These Chemicals Fight Pests

I’ve spent enough time head-scratching over chewed-up plants and stubborn pests in my backyard to appreciate any solution that brings actual relief. Hexaflumuron and diflubenzuron belong to a group called benzoylureas, and their main trick is stopping pests from developing. They get into the insect’s system—usually once the insect eats a treated leaf or piece of wood—and mess with a key process: chitin production.

Chitin holds an insect’s outer shell together. With these chemicals in play, young insects can’t form strong exoskeletons when they molt. You end up with larvae that can’t grow up, meaning fewer adults laying eggs and fewer bugs munching on plants or wood. This focus on growth regulation matters because traditional pesticides tend to kill on contact—taking out all sorts of critters, helpful or not. By targeting life cycles and not just killing every bug in sight, we get more thoughtful, focused pest management.

Good Science Keeps Our Food and Homes Safer

Hexaflumuron shows up in bait stations for termites. Instead of spraying chemicals everywhere, pest control companies drop these stations in key spots. Termites take bait back to their nests and the whole colony suffers from failed molting and declining numbers. Studies from the U.S. Environmental Protection Agency say colonies can collapse in a matter of weeks. You see less damage to your home, and less chemical run-off heads into nearby streams or the local park.

Diflubenzuron has found a place in protecting vegetables or fruit orchards. It breaks up the breeding cycle of caterpillars, beetles, and even fungus gnats. It sticks to leaves, so only pests that eat the plant suffer, which spares a lot of useful pollinators like bees. That kind of selectivity turns out to be a big win for gardeners, orchard owners, and anyone relying on helpful insects to turn flowers into food. Food safety gets a boost, too: since these compounds don’t pile up in mammals, farmers worry less about long-term residue in the harvest.

Managing the Trade-Offs

No one likes to swap one problem for another. There’s little doubt these chemicals barely touch birds and mammals, but they aren’t without risk. Runoff can still do a number on aquatic life if folks aren’t careful about how and where they apply them. It takes steady supervision and sensible limits to make sure we don’t see fish kills or unexpected crashes in shrimp populations downstream from a farm.

A big part of this conversation points back to keeping a sharp eye on resistance. Hexaflumuron and diflubenzuron don’t act as quick-kill tools. Pests exposed too often may end up immune. Farming communities across Europe and North America have already seen this with similar products, which means we need crop rotation, alternative methods, and honest education for everyone involved—from growers to retailers.

Smarter Pest Control Starts with Us

Kids walking barefoot through the yard, dogs chasing balls, neighbors trimming their roses—these everyday scenes rely on a thoughtful balance. Chemicals like hexaflumuron and diflubenzuron keep pests from taking over, but the price of convenience lies in careful use, clear science, and respect for more than just the crop or the paycheck. Those lessons don’t show up on a product label, but they spill over into how we approach every new problem, inside or out.

Is Hexaflumuron / Diflubenzuron safe for humans and pets?

Understanding Why People Use Hexaflumuron and Diflubenzuron

Hexaflumuron and diflubenzuron often show up in products meant to fight insects that attack homes, gardens, or farms. These chemicals work by stopping bugs from growing and maturing, which helps limit their populations. Many people turn to them when battling termites, fleas, or crop pests. Homeowners hear promises of safe, targeted action, especially compared to old-school pesticides.

The Facts Behind Safety For Humans

Anyone who’s handled ant powders or termite baits has probably thought about what’s inside those pest killers. Government agencies, including the U.S. Environmental Protection Agency (EPA), have reviewed both hexaflumuron and diflubenzuron. The EPA labeled diflubenzuron as “not likely to be carcinogenic to humans” if used as directed. Hexaflumuron has cleared review for safety in termite baits placed under homes, meaning common household exposure is low.

Problems usually come from misuse, like eating or directly handling large amounts. Diflubenzuron can break down in the body into a chemical called 4-chloroaniline, which, in huge amounts, poses a risk. Medical literature reports rare cases where over-exposure can damage blood, causing a problem called methemoglobinemia. Most people using products with these chemicals won’t face these issues if they follow instructions and keep products out of reach of children.

Risks for Pets At Home

Pet safety matters to anyone using pesticides. Veterinarians often see accidental poisonings after pets chew bait stations or lick up powder. At recommended levels, diflubenzuron and hexaflumuron cause mild or no symptoms in dogs and cats. High doses might bring on vomiting, loss of appetite, or unusual tiredness. Again, trouble almost always comes from pets getting into things they shouldn’t.

Pet owners should watch where baits and treatments get placed—prefer out-of-reach spots or tamper-resistant stations. Reading product labels every time can prevent an emergency. If a pet eats a large dose, a fast call to a vet makes a difference.

What Science Says About Environmental Impact

Sometimes people overlook what these pesticides do outside their homes. Hexaflumuron and diflubenzuron don’t stick around in soil as long as old insecticides, and they don’t show up easily in groundwater. Diflubenzuron is toxic to some aquatic creatures, like shrimp, so spills matter if you treat lawns near water.

Gardeners and farmers should follow directions for mixing and applying these products. That way, birds, bees, fish, and frogs stay safe, and pesticide drift to creeks or wells drops. Solutions include using bait stations for termites instead of broad spraying or choosing targeted treatments for gardens.

The Common Sense Approach

Anyone using pesticides can lower risks for family and pets with a few habits: store chemicals in locked places, wash hands after use, and toss out leftovers in safe ways. Knowledge counts as much as the product label.

As someone who’s had to fight ants in the kitchen, I keep pest baits under appliances where my dog can’t sniff them. For outdoor use, I rope off sprayed areas till dry. These steps take only a minute and keep everyone safe.

Neither hexaflumuron nor diflubenzuron works as a magic fix. Each comes with pros and cons. Staying informed, asking pest control pros for advice, and looking for alternative options like integrated pest management all help balance pest control and safety.

What are the application methods and dosages for Hexaflumuron / Diflubenzuron?

Getting to Know the Basics

Hexaflumuron and diflubenzuron grab my attention for how they shake up standard pest management. These chemicals cut down on bugs not by poisoning adults, but by interfering with molting. Insects never make it out of their shells, so they die off slowly, which means less chance for resistance to build. Both belong to the benzoylurea class and show up mostly in agriculture, forestry, and even in urban pest management strategies.

Hexaflumuron: How It’s Applied and Used

Hexaflumuron stood out for a key reason—it found its fame as a bait in termite control systems. The most familiar setup uses cellulose-based bait stations loaded with hexaflumuron. Worker termites pick up the chemical and share it back at the colony, so the whole population gets hit. Application happens with pre-manufactured bait cartridges installed into the soil around structures.

For dosage, cartridge concentrations usually float around 0.5% active ingredient. Each station holds about 120 to 150 grams of bait, replaced as termites consume it or every few months if the feeding slows. I’ve seen pest operators swear by this more sustainable approach. Field data from the US Department of Agriculture show that full colony elimination often kicks in after 3 to 6 months, with expert monitoring crucial to avoid missed spots.

In my own experience with homeowners, those open to slow-acting, less disruptive controls appreciate the way hexaflumuron sidesteps the health risks of broad-spectrum sprays and, even better, doesn’t require drilling into floors or walls the way traditional liquid termiticides often do.

Diflubenzuron: Versatile and Well-Studied

Diflubenzuron’s reach extends further, especially in crops and forest management. Sprays, dusts, and even aerial applications keep pests like gypsy moths, locusts, and caterpillars away. As a water-dispersible granule or suspension concentrate, diflubenzuron finds its sweet spot in foliar sprays. Doses typically run at 25 to 75 grams of active ingredient per hectare. Spray volume changes with crop type, but most orchards and vegetable fields receive enough carrier fluid to cover foliage—usually 400 to 1,000 liters per hectare by ground equipment.

In mosquito management, municipal teams add bridged doses of diflubenzuron to stagnant water—roughly 0.5 to 2 milligrams per liter, for controlling larvae. This low dose matters because non-target aquatic life, like fish and amphibians, show fewer side effects at these levels. Regular follow-up keeps waters from acting as breeding grounds.

Problems pop up with resistance and accidental exposure. Continuous monitoring, rotating pesticides, and using integrated pest management (IPM) have become more than recommendations—they’re necessities. The European Food Safety Authority and EPA both stress safe handling, with gloves and proper storage to limit accidental human or animal contact.

Finding Balance in Chemical Tools

The appeal of these insect growth regulators echoes my own preference for targeted, safer solutions over blanket sprays. Both are not silver bullets. The better path means matching application to real pest pressures, taking weather and crop cycles into account, and incorporating physical and biological controls whenever possible. In my time working with growers and city pest teams, I’ve watched energetic teams use these tools as part of a system—not a reflex. That’s the kind of thinking that pushes both safety and effectiveness, helping limit problems like pesticide run-off and resistance, all while keeping harvests and homes more secure for folks who count on them.

Are there any environmental impacts or restrictions when using Hexaflumuron / Diflubenzuron?

The Story Behind These Pesticides

Hexaflumuron and diflubenzuron belong to a class of chemicals called insect growth regulators. Farmers and pest control operators value them because they play havoc with an insect's ability to molt, effectively breaking pest lifecycles. They show up in termite baits, fruit orchards, and forestry projects. These compounds might seem like silver bullets—targeted, potent, and not directly toxic to mammals. Still, there's more to the story than what the label claims.

How Environment Pays the Price

After years in agriculture and watching the ebb and flow of new chemistry, I’ve become cautious about claims that any pesticide stays where it’s put. Both hexaflumuron and diflubenzuron end up in soil and water. Diflubenzuron has been detected in runoff from treated fields and forests. In a 2020 U.S. Geological Survey study, diflubenzuron residues persisted in surface water at concentrations risky for aquatic insects and some species of fish. The agency noted that insect nymphs and larvae can be more sensitive than mature insects, meaning stream life isn’t so safe.

Birds and terrestrial mammals typically face lower direct risks—these compounds target chitin, which only insects and crustaceans build—but the food web ties everyone together. In the California rice fields where I used to work, treatments knocked out aquatic midges, stunting the diets of frogs and swallows during peak breeding. If regulators only track what happens to individual pest bugs and not to the broader ecological net, real damage gets missed.

Regulations Try to Keep Problems Contained

Government agencies do set limits, sometimes outright bans, on the use of these chemicals near sensitive waterways. In the European Union, diflubenzuron received major restrictions for use in forests due to threats to non-target arthropods and aquatic ecosystems. Certain states in the U.S. now require buffer zones between treated land and water bodies; enforcement, though, often depends on whether someone notices a problem after the fact.

Regular sprayers face paperwork and training to avoid accidental drift. Labels demand that applicators keep treated surfaces away from wind. For pest control operators, hexaflumuron’s use in termite baits avoids broad spraying, but improperly disposed bait stations can still contaminate local soils. From what I’ve seen, even experienced users make mistakes during hectic workdays, and nobody watches stormwater runoff unless regulations bring real teeth.

Better Paths for the Future

Sustainable pest management doesn’t only mean swapping one chemical for another. Integrated practices—rotating crops, using beneficial insects, shifting planting dates—hold real power to reduce the dependence on these pesticides. Water-friendly buffer strips work, trapping chemical runoff before it reaches streams. In some fruit orchards, netting and pheromone traps reduce the need for growth regulators entirely.

Policy brings progress when it listens to land managers as well as scientists. The tools and training for stewardship grow stronger when end-users help shape the rules. We shouldn’t pretend that any pesticide, no matter how targeted, comes without risk. It’s easy to lean on technical fixes and forget about nature’s complexity, but land and water demand respect, not shortcuts.

Hexaflumuron / Diflubenzuron
Names
Preferred IUPAC name N-[(3,5-dichloro-4-fluorophenyl)carbamoyl]-2,3-dihydro-2,2-dimethyl-7-(trifluoromethyl)benzofuran-4-carboxamide
Other names Ascend
Consult
Cycluron
Dimilin
Grubguard
Micromite
OMS-2017
Shinlin
Spotless
Veclean
Pronunciation /ˌhɛksəˌfluːmjʊˈrɒn/ /daɪˌfluːˈbɛnzjʊˌrɒn/
Identifiers
CAS Number 86479-06-3 / 35367-38-5
3D model (JSmol) Hexaflumuron (JSmol 3D model string): ``` CC1=NC(=O)N(C(=O)N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)F ``` Diflubenzuron (JSmol 3D model string): ``` C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)F)F ``` *(These are SMILES strings commonly used for 3D modeling with JSmol.)*
Beilstein Reference 4-26-00-04055
ChEBI CHEBI:91572
ChEMBL CHEMBL1782856
ChemSpider Hexaflumuron: "151511" Diflubenzuron: "11694
DrugBank DB11260
ECHA InfoCard 03b110a6-4db7-4e44-aa83-83da2c2df37c
EC Number 606-051-00-8
Gmelin Reference Gmelin Reference: "Gmelin 41(3)230
KEGG hexaflumuron: C18730 diflubenzuron: C11127
MeSH D02.705.400.625.465
PubChem CID Hexaflumuron: "9831128" Diflubenzuron: "3030
RTECS number MB3600000
UNII PNQ70JU75I
UN number UN3077
CompTox Dashboard (EPA) CompTox Dashboard (EPA)" for Hexaflumuron: **DTXSID4045822** "CompTox Dashboard (EPA)" for Diflubenzuron: **DTXSID8020727**
Properties
Chemical formula C16H8Cl6F2O7
Molar mass 461.2 g/mol
Appearance White crystalline solid
Odor Odorless
Density 1.44 g/cm³
Solubility in water Hexaflumuron: 0.016 mg/L (20°C), Diflubenzuron: 0.1 mg/L (20°C)
log P 3.5
Vapor pressure Hexaflumuron: 3.1 × 10⁻⁸ mmHg (25°C); Diflubenzuron: 1.7 × 10⁻⁷ mmHg (25°C)
Acidity (pKa) 10.31
Basicity (pKb) 3.75
Magnetic susceptibility (χ) Diamagnetic
Refractive index (nD) 1.627
Dipole moment Hexaflumuron: 2.78 D Diflubenzuron: 3.78 D
Thermochemistry
Std molar entropy (S⦵298) Diflubenzuron: "364.0 J·mol⁻¹·K⁻¹
Std enthalpy of combustion (ΔcH⦵298) Hexaflumuron: "-823.6 kJ/mol" Diflubenzuron: "-629.2 kJ/mol
Pharmacology
ATC code QC856
Hazards
Main hazards Possible health hazard. Avoid breathing dust. Avoid contact with skin and eyes.
GHS labelling GHS07, GHS09
Pictograms GHS07
Signal word Warning
Hazard statements H317, H351, H410
Precautionary statements P264, P270, P273, P280, P301+P312, P305+P351+P338, P330, P337+P313, P501
NFPA 704 (fire diamond) Hexaflumuron / Diflubenzuron: "1-1-0
Lethal dose or concentration LD₅₀ (oral, rat): >5000 mg/kg
LD50 (median dose) LD50 (median dose): >5000 mg/kg (oral, rat)
PEL (Permissible) There is no PEL (Permissible Exposure Limit) established for Hexaflumuron or Diflubenzuron.
REL (Recommended) 0.02 mg/m³
IDLH (Immediate danger) Not established
Related compounds
Related compounds Chitin synthesis inhibitors
Benzoylureas
Lufenuron
Teflubenzuron
Triflumuron
Novaluron