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Product Name: Hexaethyl Tetraphosphate
Synonyms: HETP, hexaethyl pyrophosphate
Chemical Formula: C8H21O7P3
Recommended Use: Pesticide, insecticide (historic, use highly restricted)
Manufacturer/Supplier: –
Emergency Telephone: Local poison control center, CHEMTREC, or emergency services
Classification: Extremely hazardous by inhalation, skin contact, ingestion
Acute Health Hazards: Causes cholinesterase inhibition, twitching, convulsions, respiratory distress
Chronic Health Hazards: Repeated low-level exposure may damage nervous system
Target Organs: Central nervous system, lungs, liver
GHS Label Elements: Danger – fatal if swallowed, skin and respiratory irritant, toxic to aquatic life
Signal Word: Danger
Chemical: Hexaethyl Tetraphosphate
CAS Number: 78-40-0
Percent Composition: >90% pure
Impurities: May contain trace amounts of phosphoric esters
Other Ingredients: None declared
Inhalation: Move person to fresh air, provide oxygen, seek immediate medical attention
Skin Contact: Remove contaminated clothing, wash thoroughly with soap and water, urgent medical care required
Eye Contact: Flush eyes with water for at least 15 minutes, consult ophthalmologist
Ingestion: Rinse mouth, give activated charcoal if conscious, do not induce vomiting, get medical help without delay
Notes for Doctors: Atropine and pralidoxime recommended antidotes; monitor for respiratory depression
Suitable Extinguishing Media: Carbon dioxide, dry chemical, alcohol-resistant foam
Unsuitable Extinguishing Media: Water jets may cause spreading
Hazardous Combustion Products: Irritant and toxic fumes, including phosphorus oxides and carbon monoxide
Firefighter Protection: Full body suit, self-contained breathing apparatus
Special Hazards: Containers may rupture in heat, runoff water may pollute waterways
Personal Precautions: Avoid breathing vapors, wear personal protective equipment, ventilate area
Environmental Precautions: Prevent entry into sewers, watercourses, and soil
Spill Clean-Up Methods: Absorb with inert material, sweep up and place in approved chemical waste container, wash spill area with detergent solution
Decontamination: Use sodium hydroxide or sodium carbonate solution to neutralize residues
Disposal: Follow local, regional, and national regulations for hazardous waste
Handling: Use in well-ventilated chemical fume hood, avoid inhalation and contact with skin or eyes, keep away from food or drink
Hygiene Measures: Thorough hand washing after use, no eating, drinking, or smoking near work area
Storage Conditions: Keep in tightly sealed original container, in cool, dry, well-ventilated space, out of direct sunlight and heat sources
Incompatible Materials: Strong acids, alkalies, oxidizers
Storage Temperature: Recommended below 25°C (77°F)
Engineering Controls: Mechanical exhaust, process enclosures, eyewash stations, emergency showers
Exposure Limits: OSHA, NIOSH, and ACGIH STEL/PEL: None officially assigned for HETP; treat as highly toxic
Respiratory Protection: Full-face respirator with organic vapor cartridge, or powered air purifying respirator if available
Skin Protection: Chemical-resistant gloves (nitrile, Viton), impervious clothing, boots
Eye/Face Protection: Chemical splash goggles, face shield
Work Practices: Remove contaminated clothing directly after use, dispose as hazardous waste
Appearance: Colorless to pale yellow oily liquid
Odor: Faint, characteristic ester-like
Melting Point: -42°C (-43.6°F)
Boiling Point: 215°C (419°F) at 14 mmHg
Flash Point: 125°C (closed cup)
Density: 1.27 g/cm³ at 20°C
Solubility: Miscible with most organic solvents, hydrolizes in water
Vapor Pressure: 0.6 mm Hg at 25°C
pH: Not applicable (not water soluble)
Partition Coefficient: n-octanol/water logP: Data not fully established
Chemical Stability: Stable in closed containers at recommended storage conditions
Conditions to Avoid: Strong heat, light, moisture
Incompatible Materials: Strong acids, strong bases, oxidizers
Hazardous Decomposition Products: Phosphorus oxides, ethyl compounds, flammable vapors
Polymerization: Not expected under normal conditions
Routes of Exposure: Skin, eye, inhalation, oral
Acute Toxicity: Highly toxic, LD50 (oral, rat): 1.12 mg/kg; LD50 (skin, rabbit): as low as 2 mg/kg
Symptoms: Nausea, vomiting, muscle twitching, sweating, difficulty breathing, unconsciousness, convulsions
Delayed Effects: Possible long-term nerve, liver dysfunction after exposure
Carcinogenicity: Not classified by EPA or IARC
Other Data: Inhibits acetylcholinesterase activity, may lead to respiratory failure without prompt treatment
Ecotoxicity: Highly toxic to aquatic life, fish, invertebrates, beneficial insects
Persistence and Degradability: Decomposes in water over time, but hydrolysis products are still hazardous
Bioaccumulation: Not expected to bioaccumulate significantly
Mobility in Soil: Can leach to groundwater, risk to drinking water sources
Other Hazards: Runoff can cause serious environmental harm even at low concentrations
Disposal Methods: Hand over as hazardous waste to authorized incinerator with flue gas scrubbing, dilution or neutralization not appropriate for large amounts
Contaminated Packaging: Must also be collected and disposed of as hazardous material
Precautions: Never discharge into drains, surface water, or soil
Regulatory Compliance: Follow regional, national hazardous waste rules, documentation required for transfer and disposal
UN Number: UN 2783
Proper Shipping Name: Organophosphorus pesticide, liquid, toxic
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: I (most restrictive)
Labels Required: Toxic (Skull and crossbones), Marine pollutant, Environmental hazard
Special Precautions: Emergency response guidebook available, restrict access during transit, use secondary containment in case of leaking
Transport Regulations: Comply with IMDG, IATA, DOT hazardous materials requirements
U.S. EPA Status: Banned for most uses; subject to Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) controls
TSCA Status: Listed, significant new use rule applies
OSHA: Hazardous substance
ECHA (EU): Subject to strict REACH authorization and restriction
Other Regulations: International and national controls limit agricultural and commercial applications; reporting required for releases or exposures exceeding federal thresholds
