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Material Safety Data Sheet for Caprylyl Glycine

1. Identification

Product Name: Caprylyl Glycine
Chemical Name: N-Octanoylglycine
CAS Number: 14246-53-8
Recommended Use: Preservative, personal care ingredient
Supplier Information: Company details, address, contact phone, and emergency phone
Synonyms: Octanoylglycine, Glycine, N-octanoyl-
Product Form: Solid or liquid, based on manufacturer
Relevant Identified Uses: Cosmetic raw material, preservative systems, skin conditioning agent

2. Hazard Identification

Hazard Class: Not classified as hazardous under GHS; low acute toxicity
Signal Word: None
Hazard Statements: Not expected to present significant hazards to health under normal conditions
Precautionary Statements: Avoid contact with eyes and prolonged skin contact. Keep away from children and pets
Other Hazards: May cause mild irritation to eyes or skin upon direct or repeated contact

3. Composition / Information on Ingredients

Chemical Identity: N-Octanoylglycine
Concentration: 95–100% (depending on supplier specifications)
Impurities: Typically none known with relevance to hazard classification
Molecular Formula: C10H19NO3
Molecular Weight: 201.26 g/mol

4. First Aid Measures

Inhalation: Move person to fresh air; seek medical attention if symptoms develop
Skin Contact: Wash affected skin thoroughly with soap and water; remove contaminated clothing
Eye Contact: Rinse eyes cautiously with water for several minutes, lift upper and lower eyelids; seek medical advice if irritation persists
Ingestion: Rinse mouth with water; drink water to dilute; seek medical attention if large amounts swallowed or if symptoms occur

5. Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Specific Hazards: May release carbon monoxide, carbon dioxide, and nitrogen oxides upon combustion
Protective Equipment: Firefighters wear self-contained breathing apparatus and protective clothing
Fire Fighting Instructions: Cool containers with water spray to prevent bursting; avoid breathing vapors or smoke

6. Accidental Release Measures

Personal Precautions: Use personal protective equipment (gloves, eye protection) to avoid direct contact
Spill Cleanup: Collect spilled material with non-combustible absorbent, sweep and place into labeled waste container
Environmental Precautions: Prevent runoff to drains, surface waters, and soil
Methods for Containment: Cordon off spill area; ventilate the area if significant vapors present

7. Handling and Storage

Handling: Use in well-ventilated spaces, limit unnecessary direct handling, avoid dust generation, prevent eye and skin contact
Storage: Keep tightly closed in original container in a cool, dry, and well-ventilated place, away from incompatible materials
Storage Conditions: Store below 30°C, protect from light, moisture, and heat sources
Incompatible Materials: Strong oxidizing agents, strong acids, and bases

8. Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established
Engineering Controls: Provide general ventilation; use fume hood during large-scale transfers
Personal Protective Equipment—Skin: Protective gloves (nitrile, latex)
Personal Protective Equipment—Eye: Chemical safety goggles
Personal Protective Equipment—Respiratory: Not normally required; use mask for powder handling or limited ventilation
General Hygiene: Wash hands after handling and before eating, drinking, or smoking

9. Physical and Chemical Properties

Appearance: White to off-white powder or crystalline substance (may present as colorless liquid from some suppliers)
Odor: Mild, characteristic
pH (1% solution): 6.5–7.5
Melting Point: Approx. 95–100°C
Boiling Point: Not applicable or not available
Solubility: Slightly soluble in water, freely soluble in organic solvents
Flash Point: Not determined
Vapor Pressure: Not applicable
Density: Approx. 1.06 g/cm³
Partition Coefficient n-octanol/water: Not available

10. Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Not expected to react dangerously under normal use
Conditions To Avoid: Excessive heat, moisture, incompatible materials
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides under fire conditions
Incompatible Materials: Strong acids, bases, or oxidizers may trigger decomposition or hazardous reaction

11. Toxicological Information

Acute Toxicity: Low oral toxicity; oral LD50 (rat) above 2000 mg/kg
Skin Corrosion/Irritation: May cause mild irritation from repeated or prolonged exposure
Eye Damage/Irritation: May cause mild, transient irritation if splashed
Respiratory Sensitization: Not expected to produce sensitization
Chronic Toxicity: No data suggesting mutagenic, carcinogenic, or reproductive effects
Other Health Effects: May cause general discomfort if large quantities are inhaled or ingested

12. Ecological Information

Ecotoxicity: No evidence of significant toxicity to aquatic or terrestrial life; minimize environmental release
Persistence and Degradability: Expected to be readily biodegradable based on structure and use pattern
Bioaccumulation: Not expected to bioaccumulate due to physical and chemical properties
Mobility in Soil: Slight mobility due to low water solubility
Other Effects: Avoid large-scale uncontrolled release to surface waters and soil; observe regional regulatory thresholds

13. Disposal Considerations

Method of Disposal: Send to approved chemical disposal facility in accordance with local, regional and national laws
Handling of Packaging: Triple rinse empty containers; dispose as hazardous waste if contaminated
Do Not: Release product or rinsate to drains, waterways, or environment
Recycling: Recycling options depend on contamination and local guidelines

14. Transport Information

UN Number: Not regulated; not classified as a dangerous good
Proper Shipping Name: No special designation
Transport Hazard Class: None
Packing Group: None
Special Precautions: Protect from mechanical damage, moisture during transit
Transport Label: No label or placard necessary under normal regulations

15. Regulatory Information

Relevant Regulations: Product complies with cosmetic and chemical safety regulations including REACH (EU), TSCA (USA), and other national inventories
Inventory Status: Listed in major chemical inventories
Chemical Safety Assessment: Not required for substances used as cosmetic ingredients at current usage levels
Labeling: No hazard pictograms or signal words required for consumer use; observe workplace labeling requirements
Restrictions: No specific restrictions for normal commercial and industrial use; recommended to review customer country regulations