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Material Safety Data Sheet: Glucamine

Identification

Product Name: Glucamine
Synonyms: 1-Deoxy-1-(methylamino)-D-glucitol
CAS Number: 486-62-4
Recommended use: Used in pharmaceutical synthesis, analytical chemistry, some industrial applications
Manufacturer/Supplier: Refer to product label for supplier details
Emergency Phone: Check local resources or product label

Hazard Identification

Classification: Skin irritation, Eye irritation, May cause respiratory irritation
GHS Label Elements: Warning symbol, Hazard statements refer to mild irritant potential (skin, eye, respiratory)
Route of Exposure: Inhalation, Skin contact, Eye contact, Ingestion
Pictograms: Exclamation mark for irritant
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, May cause respiratory irritation, Harmful if swallowed in large quantities
Precautionary Statements: Avoid breathing dust, Use with ventilation, Wear eye/face protection

Composition / Information on Ingredients

Chemical Name: Glucamine
Common Name: Glucamine
Concentration: 98-100% pure
Impurities: Typically contains minor amounts of related sugars or amines (trace)
Molecular Formula: C7H17NO5
Molecular Weight: 195.21

First Aid Measures

Inhalation: Move to fresh air, support breathing as needed, seek medical advice for irritation or symptoms
Skin Contact: Wash with plenty of water and soap, remove contaminated clothing, seek medical help for irritation
Eye Contact: Rinse carefully with water for several minutes, remove contact lenses as needed, continue rinsing, get medical help if irritation persists
Ingestion: Rinse mouth, drink water if conscious, do not induce vomiting, seek medical assistance if symptomatic
Most Important Symptoms: Coughing, skin/eye redness, discomfort

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Hazards From Combustion: Produces carbon oxides and nitrogen oxides
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus, full protective gear
Fire/Explosion Hazard: Minimal, but dust formation may create slight explosion risk in confined spaces
Advice: Cool exposed containers with water

Accidental Release Measures

Personal Precautions: Use proper personal protective equipment, avoid breathing dust, ventilate area
Spill Cleanup: Sweep up material, collect in suitable container, avoid generating dust
Environmental Precautions: Prevent runoff to drains, soil, or waterways
Methods for Clean-Up: Gather with non-sparking tools, flush residue with water while containing run-off
Reference To Other Sections: See Exposure Controls and Disposal Considerations

Handling and Storage

Handling: Avoid contact with skin, eyes, and clothing, use in well-ventilated areas, wash hands thoroughly after use
Storage: Store in tightly closed containers in a dry, cool, well-ventilated place, protect from moisture and incompatible substances
Protective Procedures: Ground and bond containers for transfer of solid/dust
Incompatibilities: Strong acids, strong oxidizers, reducing agents

Exposure Controls and Personal Protection

Exposure Limits: None established for this compound
Engineering Controls: Use local exhaust ventilation, enclose processes to prevent airborne dust
Personal Protective Equipment: Wear safety glasses or goggles, chemical-resistant gloves, lab coat or apron, dust mask or respirator as required
Hygiene Measures: Wash thoroughly after handling, remove contaminated clothing, avoid eating/drinking in work areas

Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Odorless or slight amine-like smell
Melting Point: About 130–140°C
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water, slightly soluble in ethanol
Density: About 1.3 g/cm³
pH (solution): Around 7–9 (in water)
Flammability: Non-flammable as solid; dust can combust
Flash Point: Not applicable or >200°C (solid)
Vapor Pressure: Negligible
Partition Coefficient (log Ko/w): Not determined

Stability and Reactivity

Stability: Stable under normal conditions, avoid high heat and moisture
Incompatible Materials: Strong oxidizers, strong acids, alkali metals
Hazardous Decomposition: Carbon monoxide, carbon dioxide, nitrogen oxides may evolve on combustion
Hazardous Polymerization: Will not occur
Conditions to Avoid: Excessive heat, moisture, sources of ignition

Toxicological Information

Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Oral LD50 in rats estimated above 2000 mg/kg (low acute toxicity)
Skin Corrosion/Irritation: Mild irritant to skin
Serious Eye Damage/Irritation: Can cause temporary eye irritation
Respiratory Sensitization: No data, avoid inhaling dust
Carcinogenicity: Not classified as carcinogen, not listed by IARC, NTP, or OSHA
Reproductive Toxicity: No known effects on reproduction
STOT-SE/RE: No information on specific organ toxicity
Symptoms: Coughing, soreness, eye redness, digestive upset if ingested in quantity

Ecological Information

Ecotoxicity: Not expected to be hazardous in low concentrations
Aquatic Toxicity: Low toxicity to aquatic life
Persistence and Degradability: Biodegradable, degrades readily in environment
Bioaccumulative Potential: Low, no significant accumulation expected
Mobility in Soil: Highly soluble in water, will move through soil
Other Adverse Effects: Avoid large releases to surface water, best practice prevents unnecessary exposure

Disposal Considerations

Product Disposal: Dispose of in accordance with local, regional, national, and international regulations
Contaminated Packaging: Empty containers must be decontaminated before reuse or disposal
Waste Treatment Methods: In controlled facility, chemical incineration can be used, avoid release to environment
Special Considerations: Avoid discharge to sewers, waterways, natural environments

Transport Information

UN Number: Not classified as hazardous for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not hazardous
Packing Group: Not assigned
Special Precautions: Ensure packaging prevents dust leakage, handle as non-hazardous solid
Marine Pollutant: No
Labels: None required for transport

Regulatory Information

TSCA: Listed
EINECS: 207-635-4
REACH Status: Registered
SARA Title III: Not a Section 313 chemical
California Prop 65: Not listed
Other State Information: Not regulated
Workplace Hazard Symbols: Warn workers concerning dust and irritation hazards
International Inventories: Included in several chemical inventories globally