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Product Name: Gabapentin
Chemical Name: 1-(aminomethyl)cyclohexaneacetic acid
Synonyms: Neurontin, Gabarone
CAS Number: 60142-96-3
Recommended Use: Pharmaceutical active ingredient, anticonvulsant, nerve pain relief
Manufacturer Information: Refer to supplier or label for details
Classification: Not considered hazardous under typical conditions of use
GHS Label Elements: No symbol mandated, not classified for acute toxicity or environmental hazard
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Potential Health Effects: May cause mild irritation of eyes, skin or respiratory tract with repeated contact; ingestion of large amounts can lead to drowsiness, confusion, or unsteady movements
Precautionary Statement: Avoid inhaling powder or dust, limit unnecessary contact
Chemical Name: Gabapentin
CAS Number: 60142-96-3
Concentration: >98% pure, typical pharmaceutical formulation may include excipients and binders as inactive ingredients
Inhalation: Move to fresh air, provide oxygen support if breathing is difficult, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash affected area with soap and water, seek medical advice if irritation develops
Eye Contact: Flush eyes with plenty of water for at least 15 minutes, remove contact lenses if present and easy to do, seek medical attention for persistent discomfort
Ingestion: Rinse mouth with water, never give anything by mouth to an unconscious person, seek medical attention if feeling unwell, do not induce vomiting unless directed by medical personnel
Suitable Extinguishing Media: Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray for small fires, water may be used to cool nearby containers
Specific Hazards: Combustion may produce toxic fumes of nitrogen oxides and carbon oxides
Protective Equipment: Self-contained breathing apparatus and full protective clothing
Firefighting Advice: Move containers from fire area if it can be done safely, prevent firefighting runoff from entering water systems
Personal Precautions: Wear protective clothing, gloves, safety glasses, dust mask or respirator if ventilation is inadequate
Environmental Precautions: Avoid discharge to sewers and drains, contain and collect spillage
Methods for Cleanup: Scoop up solid or powder material without generating dust, clean area with damp cloth, dispose of collected material in accordance with local regulations
Safe Handling: Minimize dust generation, keep containers tightly closed, use in well-ventilated area, practice good hygiene and avoid unnecessary contact
Storage Conditions: Store in original container, keep in cool, dry area away from incompatible materials such as oxidizers, protect from moisture and light
Specific End Uses: Pharmaceutical production, laboratory research, not for unauthorized use or distribution
Engineering Controls: Use local exhaust ventilation, isolate work area during large-scale manufacturing
Personal Protective Equipment: Wear gloves (nitrile recommended), lab coat, safety glasses with side shields, respiratory protection if ventilation is inadequate
Exposure Limits: No occupational exposure limit established for gabapentin; minimize airborne dust
Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: 162–166°C
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water, slightly soluble in methanol, insoluble in most organic solvents
pH (1% Solution): Approximately 6.5–7.5
Vapor Pressure: Not volatile
Density: 1.2–1.3 g/cm³
Partition Coefficient (Log Pow): -1.1 to -1.3
Chemical Stability: Stable under normal conditions, sensitive to moisture and light
Conditions to Avoid: Excess moisture, high temperatures, strong light
Incompatible Materials: Strong oxidizing agents
Hazardous Decomposition Products: Emits toxic fumes under fire conditions including carbon monoxide, carbon dioxide, and nitrogen oxides
Polymerization: Will not undergo hazardous polymerization
Acute Toxicity: Oral LD50 (rat) >8,000 mg/kg; low acute toxicity
POTENTIAL HEALTH EFFECTS: No evidence of mutagenicity or carcinogenicity from animal studies, some reports of mild drowsiness, dizziness, or coordination issues in humans with overexposure
Skin and Eye Contact: May cause mild, temporary irritation
Chronic Effects: Long-term occupational exposure data limited; medical monitoring may help for production workers
Target Organs: Central nervous system
Ecotoxicity: Limited data, low bioconcentration potential, not expected to bioaccumulate
Persistence and Degradability: Partial biodegradation in the environment, not persistent under most conditions
Mobility in Soil: Readily soluble, may leach to groundwater with improper disposal
Other Adverse Effects: No significant impact expected at pharmaceutical use levels, risk of aquatic toxicity with large accidental releases remains low but possible
Waste Disposal Methods: Treat as pharmaceutical waste, incineration or disposal through licensed chemical disposal contractor, avoid flushing into sewers or watercourses
Contaminated Packaging: Dispose of in accordance with local and national regulations, empty containers may retain trace residues, handle as for unused product
UN Number: Not regulated as a dangerous good
Proper Shipping Name: Gabapentin, not classified as hazardous material for transport
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Environmental Hazards: Not classified as marine pollutant or environmentally hazardous for transport purposes
Special Precautions: Use sealed packaging to prevent contamination or spills during transit
TSCA Inventory: Not listed
EU REACH Status: Exempt as active pharmaceutical ingredient
OSHA Status: Not hazardous
WHMIS Classification (Canada): Not controlled
Other International Regulations: Not classified as hazardous chemical under GHS or major global chemical control lists
Labeling Requirements: Follow specific requirements for pharmaceuticals, prescription-only labeling standards apply in most countries
