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Product Name: Fosfomycin Calcium
Chemical Formula: C3H5CaO4P
Synonyms: Calcium fosfomycin, Fosfomicin calcium salt
CAS Number: 26016-99-9
Recommended Use: Pharmaceutical raw material, antibiotic
Manufacturer Details: [Manufacturer name and contact required]
Emergency Number: [To be provided by supplier]
GHS Classification: Not classified as hazardous (based on current data, but local regulations may differ)
Signal Word: Not applicable
Hazard Statements: May cause mild irritation upon contact with eyes, skin, or if inhaled
Precautionary Statements: Avoid breathing dust, wear appropriate protection, wash hands after handling
Potential Health Effects: Prolonged or repeated exposure could trigger hypersensitivity or allergic reactions in some people
Environmental Hazards: No major environmental hazards have been recorded, though large-scale release should be avoided
Chemical Name: Fosfomycin calcium
CAS Number: 26016-99-9
Weight Percentage: Typically more than 98% active ingredient
Impurities: Minor trace amounts of byproducts not considered hazardous
Eye Contact: Rinse thoroughly with water for several minutes, remove contact lenses if present, continue rinsing
Skin Contact: Remove contaminated clothing, wash skin with soap and water
Inhalation: Move exposed person to fresh air, seek medical attention if symptoms develop
Ingestion: Rinse mouth with water, do not induce vomiting, consult physician if unwell
Notes for Physicians: Treat symptomatically; allergic reactions may require antihistamines or corticosteroids
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Unsuitable Extinguishing Media: High-pressure water jets may spread powder
Special Hazards: Combustion may generate oxides of phosphorus, carbon, and calcium
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Specific Methods: Prevent entry of extinguishing media and runoff into drains or watercourses
Personal Precautions: Evacuate unnecessary personnel, avoid dust formation, use personal protective equipment
Environmental Precautions: Prevent release into soil, sewers, or waterways
Methods for Containment: Sweep or scoop up material, avoid creating dust clouds
Clean-Up Methods: Collect in a suitable container for disposal under local regulations, ventilate area, wash spill site after removal
Handling: Minimize dust generation, avoid contact with skin and eyes, provide adequate ventilation especially in bulk handling areas
Storage Conditions: Store tightly closed at 2-8°C in a dry, well-ventilated area, protected from light and incompatible substances
Incompatible Materials: Strong oxidizing or reducing agents
Specific End Use: Production of pharmaceuticals; avoid mixing with substances for which compatibility has not been established
Occupational Exposure Limits: Not established by OSHA, ACGIH, or NIOSH
Engineering Controls: Use local exhaust ventilation to control dust
Personal Protective Equipment:
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not determined
pH (1% solution): Approximately 7 to 9
Melting Point: Decomposes before melting
Boiling Point: Not applicable
Solubility: Freely soluble in water
Density: 0.8–1.0 g/cm³
Vapor Pressure: Not applicable
Partition Coefficient: Not available
Autoignition Temperature: Not determined
Decomposition Temperature: >180°C
Particle Size: Generally, fine powder with particle size below 100 microns
Chemical Stability: Stable under recommended storage conditions, sensitive to light and moisture
Reactivity: No dangerous reactions documented under normal use
Conditions to Avoid: High humidity and exposure to strong sunlight
Materials to Avoid: Strong acids, bases, oxidizers, and reducers
Hazardous Decomposition Products: Phosphorus oxides, calcium oxides, carbon oxides
Polymerization: Won’t occur under normal handling
Acute Toxicity:
Aquatic Toxicity: Data limited, but significant effects on aquatic life not suggested by current studies
Terrestrial Toxicity: No known harmful effects on soil organisms at typical contamination levels
Bioaccumulation: Not expected
Mobility in Soil: Compound is water soluble and may migrate through soil
Persistence: Degrades in the environment under microbial action, not considered persistent
Other Adverse Effects: Avoid release in large quantities to environment as a precaution
Disposal Methods: Dispose of in accordance with local, regional, national, and international laws
Waste Treatment Options: Deliver to approved chemical disposal facility or incinerate under controlled conditions
Packaging Disposal: Empty containers should be triple-rinsed and offered for recycling where possible, otherwise dispose as chemical waste
Precautions: Do not contaminate water, food, or feed by disposal
UN Number: Not regulated for transport
UN Proper Shipping Name: Not classified as dangerous for transport
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Marine Pollutant: No
Special Transport Precautions: Store securely to prevent damage or leaks during transit, avoid extreme temperatures, keep dry
US Regulations: Not listed as a hazardous substance under TSCA, CERCLA, SARA, RCRA
European Union: Not classified as hazardous under Regulation (EC) No 1272/2008
Workplace Safety: Implementation of written safety and handling procedures is strongly recommended
Other Relevant Regulations: Food and pharmaceutical-grade materials subject to additional approval and licensing, customs export controls might apply
