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Product Name: Firocoxib
Chemical Formula: C17H20O5N3S
CAS Number: 189954-96-9
Synonyms: Previcox, Equioxx
Product Use: Veterinary anti-inflammatory drug (COX-2 inhibitor)
Manufacturer: Pharmaceutical laboratory or veterinary supplier details as listed on product label
Emergency Contact: Refer to local poison control center or regulatory agency
Recommended Restrictions: For animal treatment only, not for use in animals intended for human consumption
Classification: Harmful if swallowed; may cause allergic reactions upon contact or inhalation; possible target organ effects; not classified as flammable
Signal Word: Warning
Hazard Statements: Causes eye and skin irritation, harmful if inhaled or absorbed through skin, may cause gastrointestinal and renal disturbances after ingestion, long-term exposure may damage organs
Pictograms: Health hazard, exclamation mark
Precautionary Statements: Use gloves and eye protection, avoid inhalation, wash hands thoroughly after handling, do not eat or drink when using this product
Potential Health Effects: Overexposure symptoms include nausea, vomiting, abdominal pain, skin or eye irritation, respiratory tract irritation
Active Ingredient: Firocoxib (Purity ≥99%)
Other Ingredients: Trace surfactants, excipients, stabilizers, binders as listed on proprietary blend
Impurities: Less than 0.1%, composed mainly of process-related organic compounds
Concentration: Pure compound as supplied is 100% Firocoxib; finished dosage forms may vary by manufacturer
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, seek medical advice if irritation develops
Skin Contact: Wash skin with mild soap and water, remove contaminated clothing, seek attention if redness or blistering appears
Inhalation: Move affected person to fresh air, monitor for difficulty in breathing, seek medical attention if symptoms persist
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel, contact a poison control center for advice
Note to Physician: Provide symptomatic treatment; no specific antidote available
Extinguishing Media: Use carbon dioxide, dry chemical powder, foam, or water spray as appropriate for surrounding fire
Hazards from Combustion: Toxic fumes of carbon monoxide, sulfur oxides, nitrogen oxides, other undetermined decomposition products
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective clothing, evacuate area nearby if significant amounts burn
Specific Methods: Cool containers exposed to fire with water, avoid dispersing dust from powdered product
Personal Precautions: Avoid creating dust, wear suitable respiratory protection, gloves, and safety goggles
Environmental Precautions: Prevent product entering drains or watercourses, use soil or sand to contain spill if necessary
Methods for Cleanup: Sweep or scoop up without creating dust, transfer to a sealed and labeled container, ventilate area after cleanup, dispose according to local regulations
Decontamination: Wash spill area with water and detergent, collect rinsate for proper disposal
Safe Handling: Handle in a well-ventilated space, avoid breathing dust or vapors, do not ingest, prevent contact with skin, eyes, or clothing
Prohibited Practices: Eating, drinking, or smoking in areas where product is handled or stored
Safe Storage Conditions: Store in original closed container, keep in a cool, dry, well-ventilated location, away from direct sunlight, incompatible substances include strong oxidizers and acids
Special Provisions: Keep out of reach of children and unauthorized personnel, prevent freezing or excessive heat
Engineering Controls: Use local exhaust ventilation to minimize exposure to airborne dust
Personal Protection: Wear lab coat or protective clothing, chemical-resistant gloves, safety goggles, and dust mask or respirator if dust is generated
Exposure Guidelines: No established occupational exposure limit for firocoxib, use good industrial hygiene practice to minimize risk
Hygiene Measures: Wash hands and face before breaks and at end of work, do not reuse contaminated clothing until washed
Appearance: White to off-white crystalline powder
Odor: Odorless or faint chemical smell
Melting Point: 216-218 °C
Boiling Point: Decomposes before boiling
Solubility in Water: Insoluble, soluble in organic solvents like methanol or acetonitrile
Density: Approximately 1.29 g/cm³ at 20°C
Vapor Pressure: Not significant at room temperature
pH: Neutral to slightly acidic in aqueous suspension
Flash Point: Not applicable under expected conditions
Chemical Stability: Stable under recommended storage and use conditions
Reactivity: Not reactive with most substances under normal handling
Hazardous Decomposition: Exposure to fire produces toxic fumes including CO, NOx, SOx
Incompatible Materials: Strong oxidizers, acids, alkalis
Polymerization: Will not undergo hazardous polymerization
Likely Routes of Exposure: Ingestion, inhalation, skin and eye contact
Acute Toxicity: Oral LD50 (rat): >2000 mg/kg; Dermal LD50 (rat): >2000 mg/kg
Symptoms of Overexposure: Gastrointestinal upset, skin rashes, headache, dizziness, allergic reactions
Chronic Toxicity: Long-term exposure can affect renal system, potential for reproductive or developmental toxicity based on animal studies
Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA
Mutagenicity: Not found to be mutagenic in standard tests
Reproductive Effects: Evidence of fetal toxicity in animal studies at high doses
Ecotoxicity: Harmful to aquatic organisms, causes long-term adverse effects in aquatic environments
Environmental Fate: Persists in soil and sediment, low bioaccumulation in aquatic organisms, not rapidly biodegradable
Mobility: Low mobility in soil due to high molecular weight and low solubility
Aquatic Toxicity: LC50 (fish): ≥1 mg/L (estimated); EC50 (daphnia): ≥1 mg/L (estimated)
Other Adverse Effects: No known ozone depletion or groundwater contaminant effects under normal usage
Disposal Methods: Collect and place in tightly sealed containers for incineration under approved chemical waste guidelines
Contaminated Packaging: Triple rinse and puncture empty containers, dispose as chemical waste, do not reuse
Waste Codes: Dispose in accordance with local, regional, national, and international regulations for pharmaceutical and hazardous waste
Precautions: Do not release into environment, avoid contamination of sewers, streams, or soil
UN Number: Not classified as dangerous for transport under ADR/RID, IMDG, IATA
Proper Shipping Name: Firocoxib as shipped or trade-specific name
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Special Precautions: Prevent movement or breakage during transport, ship in original containers, follow all local and international regulations
Labelling Requirements: As per local and international chemical and pharmaceutical standards
Regulatory Status: Prescription veterinary drug under FDA and EMA guidelines
REACH Information: Not registered for chemical production or general industry except for veterinary use
SARA Title III: Not subject to reporting requirements
Other Regulations: Handled and distributed under veterinary and pharmaceutical jurisdiction, not listed as a controlled substance
