© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Name: Everolimus Chemical Formula: C53H83NO14 CAS Number: 159351-69-6 Form: Solid, white to off-white powder Common Uses: Treatment for certain cancers, transplant rejection prevention Routes of Exposure: Inhalation, ingestion, skin and eye contact
Health Hazards: Immunosuppressive agent, may lower ability to fight infections, risk of mouth ulcers, increased cholesterol, non-infectious pneumonitis reported with exposure, potential for kidney or liver trouble with chronic exposure, unsafe exposure levels not established but no deliberate contact suggested Environmental Hazards: Risk of toxicity in aquatic environments if released in quantity Fire or Explosion Risk: Dust buildup and fine particulates contribute to respiratory irritation and can become combustible with sufficient accumulation
Main Ingredient: Everolimus Purity: Typically above 98% when supplied in pure form Inactive Ingredients: Not relevant in isolated substance state Known Impurities: Minimal, pharmaceutical-grade handling reduces risk
Inhalation: Move affected individual to fresh air, seek medical attention if symptoms, such as respiratory discomfort or coughing persist Skin Contact: Remove contaminated clothing, wash exposed area well with soap and water, look for rash or persistent irritation, consult a healthcare provider if required Eye Contact: Flush eyes thoroughly with water, check for redness or blurred vision, prompt evaluation recommended if discomfort continues Ingestion: Rinse mouth, do not induce vomiting without medical supervision, immediate attention needed for larger quantities or symptoms such as dizziness or stomach upset
Suitable Extinguishing Media: Carbon dioxide, dry powder, foam Hazardous Combustion Products: Emits toxic fumes, potential for nitrogen oxides and carbon oxides under intense heat Protective Equipment for Firefighters: Wear full protective equipment and approved self-contained breathing apparatus in enclosed areas, minimize contact with smoke or residue Fire Response: Isolate area, clear unnecessary personnel, contain runoff from fire control to prevent environmental contamination
Personal Precautions: Wear gloves, mask, and goggles Environmental Precautions: Prevent release into soil or water systems, avoid dust formation Spill Cleanup Methods: Gently collect powders, mop with damp disposable material, deposit waste in sealed container designated for pharmaceutical disposal Decontamination: Wash surfaces and hands thoroughly after spill management, ventilate area thoroughly to remove lingering dust
Handling: Use protective gear to avoid exposure, avoid ingestion or inhalation, limit bottle or blister opening to controlled environments Storage: Store in tightly closed container, away from light and moisture, temperature-controlled cabinet recommended, restrict access to trained personnel only Incompatible Materials: Avoid contact with strong oxidizers, acids, and excessive heat Precautionary Tips: Do not eat, drink, or smoke where Everolimus is handled, routine cleaning of storage and preparation areas is crucial
Engineering Controls: Work under a certified chemical fume hood or with local exhaust ventilation Personal Protective Equipment: Impermeable gloves, fitted laboratory coat, goggles or full-face shield, disposable mask or respirator in dust-prone procedures Hygiene Measures: Wash hands after work, avoid contact with personal belongings, restrict hand-to-mouth contact until thoroughly cleansed Occupational Exposure Limits: No established regulatory limits, minimize exposure as a precaution Environmental Controls: Secure waste disposal and emission containment reduce environmental risk
Appearance: White to off-white crystalline powder Odor: Odorless Molecular Weight: 958.2 g/mol Melting Point: Decomposes at elevated temperature, exact data scarce Solubility: Poorly soluble in water, soluble in organic solvents like ethanol, methanol, DMSO Volatility: Negligible under normal handling pH: Not applicable as a solid, solution pH varies with solvent
Chemical Stability: Stable if kept dry and cool, light sensitive Reactivity: Generally non-reactive unless exposed to strong oxidizing agents, acids, or extreme heat Hazardous Decomposition: High temperatures cause breakdown with possible emission of noxious fumes Conditions to Avoid: Moisture, sunlight, open flames, and incompatible chemicals
Acute Toxicity: Data from animal studies suggest low acute toxicity in standard quantities, high quantities or occupational misuse can cause immunosuppression Potential Health Effects: Headaches, mouth ulcers, GI disturbance, potential kidney or liver impact, hematological abnormalities over long-term exposure Chronic Toxicity: Immunosuppressive action linked to increased infection risk and delayed healing Carcinogenicity: Not classified by IARC, available data insufficient for conclusive human rating Routes of Exposure: Dust or powder as inhalation hazard; accidental skin or eye contact may cause irritation
Ecotoxicity: Bioactive compound, chronic aquatic exposure risk, not intended for widespread environmental distribution Persistence and Degradability: Likely to undergo partial breakdown in soil and water, active ingredients may persist and affect microorganisms Bioaccumulative Potential: Evidence lacking for significant bioaccumulation, but unknowns remain regarding effects on food chains Precaution: Pharmaceutical waste never belongs in regular wastewater streams for community safety
Safe Disposal: Designate as hazardous pharmaceutical waste, avoid drains or household trash, dedicated incineration recommended Handling Waste: Wear gloves, close and label all waste containers, arrange for pickup by specialized service Recycling: Not suitable for recycling given the toxic potential and lack of neutralization Regulatory Considerations: Adhere to local and national regulations for cytotoxic or hazardous substance disposal to protect workers and the environment
UN Number: Not classified as dangerous for transport by most regulatory agencies in standard therapeutic amounts Packing Group: Standard pharmaceutical transport guidelines apply, secure from contamination or accidental release Precautions in Transit: Tight packaging avoids moisture, light, accidental crushing, not shipped with food or feed Shipping Instructions: Label as pharmaceutical, provide hazard and exposure reference data for shipping personnel
Governing Agencies: FDA status as prescription drug, subject to pharmacy board handling rules, controlled handling within workplaces Occupational Guidelines: Strict access, use of safety equipment where exposure is possible Environmental Protection: Classified as hazardous waste under US EPA rules if discarded in large quantities Worker Training: Emphasize best practice protocols, reporting and managing accidental exposures
