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Product Name: Ethylene Glycol Bis(2-Aminoethyl Ether)-N,N,N',N'-Tetraacetic Acid
Synonyms: EGTA, Ethanedioic acid, EGTA tetraacetate
Chemical Formula: C14H24N2O10
Recommended Use: Chelating agent in biochemistry and analytical chemistry
Supplier: Available from many laboratory chemical providers, details on request
Emergency Contact Number: Refer to national chemical emergency numbers and poison control center listings
Classification: Not listed as hazardous under OSHA, but may cause respiratory irritation and skin, eye, or GI tract discomfort
Signal Word: Caution
Hazard Statements: Irritant (may cause irritation to skin, eyes, and mucous membranes)
Pictograms: Exclamation mark for irritant
Precautionary Statements: Avoid breathing dust; avoid contact with skin and eyes; use personal protective equipment appropriately; wash exposed skin thoroughly after handling
Chemical Name: Ethylene Glycol Bis(2-Aminoethyl Ether)-N,N,N',N'-Tetraacetic Acid
CAS Number: 67-42-5
Percent: >99% Pure in most laboratory preparations
Impurities: Water content and inorganic salts in minor trace amounts depending on manufacturer and grade
Inhalation: Move affected person to fresh air; seek medical attention if symptoms occur
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing
Eye Contact: Flush with copious amounts of water for at least 15 minutes; contact an ophthalmologist if irritation persists
Ingestion: Rinse mouth with water; do not induce vomiting; seek medical advice promptly
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical, or foam
Specific Hazards: Combustion may produce carbon oxides and nitrogen oxides
Protective Equipment: Firefighters should wear full protective gear and self-contained breathing apparatus; remove containers from fire area if safe to do so
Further Considerations: Avoid breathing fumes and runoff into surface waterways
Personal Precautions: Wear suitable PPE including gloves, lab coat, eye protection, dust mask if dust is present
Environmental Precautions: Contain spill to prevent entry into drains; keep materials out of surface water and soil
Clean-Up Methods: Sweep up solid material using methods minimizing dust formation; collect in appropriate container for disposal; ventilate area and wash spill site after material pick-up is complete
Safe Handling: Minimize dust generation and accumulation; use in a well-ventilated area; avoid contact with eyes, skin, and clothing
Hygiene Measures: Wash hands before breaks and at end of work; do not eat, drink, or smoke in working area
Storage Conditions: Store in tightly closed, labeled containers; keep in a cool, dry place protected from direct sunlight and moisture; segregate from incompatible substances, especially strong acids and oxidizers
Engineering Controls: Work in well-ventilated environment; use local exhaust ventilation if available
Respiratory Protection: Use approved particulate respirator where dust levels exceed occupational exposure limits
Eye Protection: Chemical safety goggles or face shield as appropriate
Hand Protection: Suitable protective gloves resistant to chemicals
Skin Protection: Lab coat or protective clothing
Occupational Exposure Limits: Not established for EGTA, general dust exposure limits apply; keep under 10 mg/m³ total inhalable dust
Appearance: White to off-white crystalline solid
Odor: Odorless
Melting Point: Approximately 220°C (decomposes without boiling)
Solubility: Moderately soluble in water
pH: 2.5 – 3.5 (1% solution in water)
Vapor Pressure: Negligible at room temperature
Partition Coefficient: Not determined
Boiling Point: Not applicable (decomposes)
Relative Density: 1.30 (approximate)
Flash Point: Not flammable under normal conditions
Chemical Stability: Stable under recommended storage conditions
Reactivity: Chemically inactive under normal laboratory conditions
Incompatible Materials: Strong acids, strong bases, strong oxidizing agents
Hazardous Decomposition Products: Thermal decomposition may generate carbon dioxide, carbon monoxide, and nitrogen oxides
Polymerization: No hazardous polymerization expected
Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Effects: May cause irritation of respiratory tract, gastrointestinal tract, skin, and eyes
Chronic Effects: Long-term exposure data insufficient; not listed as carcinogen by IARC, ACGIH, NTP, or OSHA
LD50 (Oral, rat): Estimated >2,000 mg/kg (low toxicity based on analogs)
Skin Sensitization: Not expected, but extended exposure can cause dryness or cracking
Eye Effects: Redness, watering, or discomfort
Medical Conditions Aggravated: Existing respiratory conditions may worsen upon exposure
Ecotoxicity: Not classified as hazardous for the environment in low volumes, but large spills can impact aquatic organisms due to elevated metal chelation in water
Mobility in Soil: Readily dispersible in water, potential for rapid movement through soil
Persistence and Degradability: Product not considered biologically degradable, can persist in environment
Bioaccumulative Potential: Not expected to accumulate in living organisms
Aquatic Data: No specific data available, chelation impact on waterborne metal ions may disrupt aquatic systems if present in bulk
Waste Treatment Methods: Collect and place material in a suitable, labeled waste container
Disposal Recommendations: Dispose of according to local, regional, or national regulations for non-hazardous laboratory chemicals; avoid disposal via drains
Contaminated Packaging: Empty containers should be rinsed and disposed in the same way as the product itself
Special Instructions: Contact a licensed chemical waste disposal contractor for bulk material
UN Number: Not regulated for transport
Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified as a dangerous good
Packing Group: Not applicable
Environmental Hazards: None known; product is not listed as a marine pollutant
Transport Precautions: Transport in sealed containers; protect from moisture and physical damage during movement
OSHA: Not listed as a hazardous chemical under the Hazard Communication Standard
TSCA: Listed
SARA 313: Not subject to reporting requirements
California Proposition 65: Not listed
REACH/CLP (Europe): Not classified as hazardous; ensure compliance for import/export
Other Restrictions: Users should check all national and international regulatory guidance before handling
