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Product Name: Ethyl Imidazo[1,2-a]pyridine-3-acetate
Chemical Formula: C11H12N2O2
Synonyms: Ethyl 3-(imidazo[1,2-a]pyridin-3-yl)acetate
Manufacturer: [Manufacturer information must be specified by the supplier]
Recommended Use: Research, chemical synthesis, laboratory reagent
Contact Information: [Emergency contact and local distributor details to be listed by user’s organization]
CAS Number: 774589-37-8
UN Number: [Consult local regulatory resources]
Hazard Classification: Not classified as hazardous according to GHS regulatory criteria, though adverse health and environmental effects may be present based on analogs and compound class.
Pictogram: No pictogram typically assigned; laboratory PPE recommended.
Signal Word: Caution
Hazard Statements: May cause irritation to eyes, skin, or respiratory tract. Avoid inhalation and direct contact.
Precautionary Statements: Wash exposed skin after handling, store in cool well-ventilated area, and follow laboratory protocols.
Route of Exposure: Eye contact, skin contact, ingestion, inhalation.
Symptoms: Burning of eyes, redness or itching of skin, coughing, stomach upset.
Chronic Effects: Evidence lacking for this compound; similar imidazo derivatives have low long-term toxicity but must be handled with respect due to incomplete toxicity data.
Chemical Name: Ethyl imidazo[1,2-a]pyridine-3-acetate
CAS Number: 774589-37-8
Concentration: 95-100% by weight (for pure laboratory grade compound)
Impurities: Minor residual solvents or byproducts possible, not expected to exceed 2%.
Additives: None reported; standard laboratory-grade material contains just the compound of interest.
General Advice: Remove affected individual from exposure. Seek medical attention for persistent symptoms.
Inhalation: Move to fresh air, rest in comfortable position, obtain medical advice if symptoms persist.
Skin Contact: Wash with soap and plenty of water. Remove any contaminated clothing.
Eye Contact: Rinse opened eye for several minutes under running water, lifting eyelids occasionally. Seek attention if irritation develops.
Ingestion: Rinse mouth with water. Do not induce vomiting. Call a physician or poison center.
Note for Physicians: No specific antidote; treat symptomatically based on clinical findings.
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, or alcohol-resistant foam.
Fire Hazards: Compound may release toxic fumes containing nitrogen oxides and carbon monoxide when heated intensely or burned.
Protective Equipment for Firefighters: SCBA and full protective gear required.
Specific Procedures: Keep containers cool with water spray. Prevent runoff from entering drains or water bodies due to chemical contamination.
Flash Point: Estimated >110°C (literature values lacking for exact number)
Special Hazards: Avoid inhalation of smoke or combustion byproducts.
Personal Precautions: Wear lab coat, gloves, goggles. Avoid generating dust. Evacuate area if necessary.
Environmental Precautions: Prevent chemical from entering soil, sewers, waterways.
Clean-Up Methods: Sweep or scoop up solid material and place in labeled container for disposal as hazardous waste. Wipe surfaces with damp cloth.
Ventilation: Maximize airflow and ventilate area after spill retrieval.
Decontamination: Wash surfaces thoroughly with mild detergent and water.
Waste Disposal: Dispose collected material in accordance with local environmental regulations.
Handling: Handle with appropriate protective equipment to avoid skin or eye contact. Use only in fume hood or well-ventilated area. Keep away from food and beverages.
Storage Temperature: Maintain in sealed container at room temperature or lower, out of direct sunlight.
Incompatibilities: Strong acids, strong bases, strong oxidizers. Separate from incompatible substances.
Storage Conditions: Store in original tightly closed container in a dry, cool, and well-ventilated place.
Hygiene Measures: Wash hands thoroughly after handling and before eating or drinking. Separate work clothes from street clothes.
Engineering Controls: Use exhaust ventilation or chemical fume hood to minimize airborne exposure.
Respiratory Protection: Use approved respirator if airborne dust or vapors are generated and proper air exchange is not possible.
Eye Protection: Wear safety goggles with side shields.
Skin Protection: Nitrile or neoprene gloves, long-sleeved lab coat recommended.
Other Protective Measures: Do not eat, drink, or smoke while handling; keep away from unprotected personnel.
Exposure Limit Values: No occupational exposure limits established; handle as if potentially hazardous.
Appearance: Off-white to light yellow powder or crystalline solid
Odor: No characteristic odor, mild chemical scent
Odor Threshold: Data not available
pH: Not applicable (solid); soluble in some polar organic solvents
Melting Point: 110-115°C (if pure; literature variations occur)
Boiling Point: Decomposes before boiling
Flash Point: >110°C (estimate)
Flammability: Not highly flammable, but combustible as organic solid
Vapor Pressure: Not measurable under standard room conditions
Solubility: Slightly soluble in water, soluble in ethanol, methanol, DMSO
Relative Density: ~1.2 g/cm³
Partition Coefficient (log Kow): Data unavailable
Decomposition Temperature: >160°C with possible toxic fumes
Chemical Stability: Stable for months under recommended storage conditions; hydrolyzes slowly under extreme acidic or basic conditions.
Hazardous Reactions: Violent reaction unlikely; reacts with strong oxidizing agents and acids or bases.
Incompatibilities: Strong oxidizers, reducing agents, potent acids or bases.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide.
Reactivity: No explosive or self-reactive properties recorded in literature or supplier's testing.
Acute Toxicity: No specific LD50 data for this compound. No direct toxicity findings; extrapolation from similar imidazo core structures indicates moderate toxicity.
Skin Corrosion/Irritation: Mild irritation may result from prolonged exposure.
Eye Damage/Irritation: Direct contact may cause irritation, redness, watering.
Respiratory Sensitization: Prolonged inhalation of dust can cause airway irritation.
Ingestion: Small amounts unlikely to cause acute toxicity, but avoid ingesting laboratory chemicals.
Mutagenicity: No available mutagenicity studies. Handle with care due to unknown long-term effects.
Carcinogenicity: Not listed by IARC, NTP, OSHA as carcinogen.
Chronic Effects: Chronic exposure studies absent. Avoid unnecessary or prolonged exposure.
Ecotoxicity: No measured ecotoxicity for this compound; analog compounds show low acute toxicity for aquatic organisms, but persistence in environment is possible.
Persistence and Degradability: Likely moderately persistent if released to environment due to aromatic ring structure.
Bioaccumulative Potential: Potential for bioaccumulation not studied; molecular size suggests low risk.
Mobility in Soil: Low to moderate; limited water solubility slows leaching.
Other Hazards: Avoid release to surface water or drains. No major ozone depletion potential.
Waste Treatment Methods: Dispose of contents and container as hazardous chemical waste.
Disposal of Product: Incinerate in licensed facility or contract hazardous waste processor.
Disposal of Contaminated Packaging: Triple rinse bottles/glassware before recycling or disposal.
Special Precautions: Follow local, state, and federal regulations. Never discharge to surface water, sewer, or environment.
UN Number: Not regulated as hazardous for ground, air, or sea transport under current guidelines.
Proper Shipping Name: Laboratory chemical; see local shipment guidelines.
Hazard Class: Not assigned.
Packing Group: Not assigned.
Special Transport Precautions: Use secondary containment during shipment. Prevent exposure to high heat or direct sunlight.
Environmental Hazards During Transport: Keep away from food and feedstuffs.
International Inventories: Not listed on TSCA, EINECS/ELINCS, DSL/NDSL for general commercial import.
U.S. Regulations: OSHA: Non-hazardous; SARA 313: Not listed; CERCLA: Not listed; California Proposition 65: Not listed as known to cause cancer, birth defects, or other reproductive harm.
EU Regulations: Not classified under REACH based on current available data.
Other Regulatory Data: User must consult local/national regulations to verify status before bulk use, especially in academic labs, pilot plants, or any process scale-up.
