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Chemical Name: Ethyl Chlorothionoformate
Synonyms: O-Ethyl chlorothiocarbonate
Common Uses: Organic synthesis, chemical research, intermediate for pharmaceuticals and agrochemicals
Appearance: Colorless to pale-yellow liquid
Odor: Pungent, sharp
Formula: C3H5ClO2S
CAS Number: 2524-04-1
Health Risks: Respiratory tract, skin, and eye irritant; may cause chemical burns; vapors dangerous when inhaled; toxic if swallowed or absorbed through the skin
Fire Hazards: Flammable, forms toxic and corrosive gases upon burning
Environmental Hazards: Harmful to aquatic life due to toxicity and persistence
GHS Classification: Corrosive to skin and eyes; acute toxicity (oral, inhalation, dermal); environmentally hazardous
Pictograms: Corrosion, skull and crossbones, environment
Active Ingredient: Ethyl Chlorothionoformate
Purity: Typically above 95% in laboratory preparations
Impurities: Trace hydrochloric acid, triethylamine, solvent residues possible from manufacturing
Inhalation: Remove person from exposure, keep comfortable, supply fresh air, seek medical attention
Skin Contact: Remove contaminated clothing, wash with soap and plenty of water for at least 15 minutes, seek prompt medical help
Eye Contact: Flush eyes cautiously with water for several minutes, continue if victim wears contacts, seek immediate medical care
Ingestion: Do not induce vomiting, rinse mouth thoroughly, call poison control or doctor without delay
Acute Symptoms: Burning sensation, coughing, breathing difficulty, red or blistered skin, eye damage
Suitable Extinguishing Media: Use foam, dry chemical powder, or carbon dioxide; avoid water jets due to chemical reactivity
Hazardous Combustion Products: Carbon oxides, hydrogen chloride, sulfur oxides, phosgene gas in intense fires
Protective Equipment: Wear full-body chemical-resistant suit, positive pressure self-contained breathing apparatus
Special Procedures: Cool containers exposed to flames with water fog; stay upwind to avoid fumes
Personal Precautions: Evacuate area, ventilate, restrict access; staff must use chemical splash goggles, gloves, and respirator
Spill Cleanup: Cover with dry earth or sand; do not use water; shovel into labeled waste containers; wash area thoroughly after removal
Environmental Precautions: Prevent product from entering drains, sewers, waterways; inform local authorities if contamination risks occur
Handling Practices: Only open in a fume hood or well-ventilated lab; never breathe vapors; avoid direct physical contact; use non-sparking tools
Storage Requirements: Keep in tightly sealed glass or compatible containers; store in a cool, dry, dedicated chemical cabinet away from bases, oxidizers, amines, and moisture
Incompatible Materials: Strong bases, water, strong oxidizers, alcohols
Protection from Light/Humidity: Store away from sunlight and atmospheric moisture, since hydrolysis releases toxic gases
Exposure Limits: No established OSHA or ACGIH TLV, but minimize exposure as much as possible
Engineering Controls: Use well-ventilated areas, chemical fume hoods, local exhaust; keep emergency showers and eyewash stations available
Personal Protective Equipment: Chemical-resistant gloves (nitrile, butyl rubber), goggles or face shield, flame-resistant lab coat, respiratory protection if ventilation lacks
Hygiene Measures: Wash hands and face after handling, remove contaminated clothing immediately, avoid eating or drinking in work areas
Physical State: Liquid at room temperature
Color: Colorless to pale yellow
Odor: Pungent, irritating
Boiling Point: About 146 °C (295 °F)
Melting Point: Below -20 °C (-4 °F)
Flash Point: Not well documented, but considered flammable
Solubility: Hydrolyzes in water to give toxic fumes
Vapor Pressure: Moderate at ambient temperatures, vapor is heavier than air
Density: Around 1.25 g/cm³
Chemical Stability: Decomposes if exposed to water, acid, or moisture in air
Thermal Decomposition: Breaks down rapidly at high temperatures, generating corrosive gases
Hazardous Reactions: Violent with water, bases, and many amines; forms toxic or irritating gases upon decomposition
Incompatible Materials: Water, strong bases, oxidizing agents, reducing agents, alcohols, amines
Acute Toxicity: Causes severe irritation; ingestion or inhalation brings symptoms such as abdominal pain, nausea, headache, breathing distress, skin and eye burns
Chronic Effects: Prolonged exposure aggravates respiratory disorders, dermatitis, sensitization possible with repeated contact
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms: Burning of eyes, nose, throat, chest; difficulty breathing; chemical burns
Carcinogenicity: No data for direct link, but related compounds show suspicion
Aquatic Toxicity: Readily toxic to fish and aquatic invertebrates
Persistence and Degradability: Breaks down slowly in soil and water without intervention; hydrolysis products can be even more dangerous to aquatic life
Bioaccumulation Potential: No reliable data, but caution necessary in all disposal and spill events
Environmental Fate: Rapid evaporation, but products of breakdown create long-term contamination risks
Waste Handling: Treat as hazardous chemical waste under controlled conditions; avoid all sewer or landfill disposal
Incineration: Possible with chemical scrubbers to remove acidic and sulfurous gases
Contaminated Packaging: Dispose of container through approved hazardous waste facility after thorough rinsing and neutralization with professional help
UN Number: Classified as dangerous under international and US transport codes
Proper Shipping Name: Organic liquid, toxic, corrosive
Transport Hazard Class: Toxic, corrosive, environmentally hazardous
Packing Group: High hazard designation due to combined toxicity and corrosive properties
Special Precautions: Only trained carriers using appropriate hazard labels and emergency response guides should handle
Chemical Inventories: Listed or regulated under US TSCA, EU REACH, and similar registries in developed nations
Hazard Communication: Labeling and training required under OSHA Hazard Communication Standard; SDS must be provided in workplaces
Restrictions: Use controls or outright bans exist in many countries except for specific research, industrial syntheses with mitigation controls
Worker Safety: National and regional regulations demand personal protective equipment and emergency facilities for any worker exposure
