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Material Safety Data Sheet – Ethopabate

Identification

Product Name: Ethopabate
Chemical Name: 4-Acetamido-2-ethoxybenzoic acid ethyl ester
CAS Number: 59-06-3
Synonyms: 4-Acetamido-2-ethoxybenzoic acid ethyl ester, Coccidiostat
Recommended Use: Veterinary pharmaceutical, coccidiostat in poultry feed
Supplier Details: Manufacturer contact information required for traceability and emergency response
Emergency Contact: National chemical spill hotline or poison control center recommended for rapid intervention

Hazard Identification

GHS Classification: Not generally considered hazardous under GHS, but may cause irritations
Main Hazards: May cause eye, skin, and respiratory tract irritation especially in cases of prolonged exposure to dust
Warning Symbols: None mandated, though precaution signs for dust inhalation advised
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Health Effects: May provoke mild discomfort or allergic reaction; symptoms could include redness, itching, mild headache after direct exposure; ingestion may cause stomach upset
Environmental Hazards: Not classified as hazardous to aquatic life in low quantities, but runoff from large spills may pose risks

Composition / Information on Ingredients

Chemical Identity: Ethopabate
Concentration: >97% pure (varying by batch, traces of residual solvents possible)
Impurities: Minor solvent residues possible from production process; other impurities not usually present in manufactured product
Additives: Typically none, but may be present in formulated feed preparations
Molecular Formula: C13H17NO4
Molecular Weight: 251.28 g/mol

First Aid Measures

Inhalation: Move the person to fresh air as a priority; if symptoms persist, medical attention advised
Skin Contact: Remove contaminated clothing immediately, rinse skin thoroughly with soap and water; prolonged irritation call for doctor consultation
Eye Contact: Rinse eyes gently with plenty of water for at least 15 minutes holding eyelids open; persistent irritation prompts examination by a medical professional
Ingestion: Rinse mouth with water; do not induce vomiting unless directed by medical staff; seek medical help if large quantity ingested
Acute Symptoms: No severe toxic effects anticipated in minor exposure cases; larger exposures require assessment for allergic reaction or gastrointestinal distress
Note for Physicians: Symptomatic and supportive care recommended; no specific antidote

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, CO2, and water spray effective; avoid using high-pressure streams that may disperse dust
Specific Hazards: Product decomposes under intense heat producing carbon oxides, nitrogen oxides, and potentially irritating vapors
Precautions for Firefighters: Wear full protective clothing including self-contained breathing apparatus to prevent inhalation of hazardous decomposition gases
Explosion Risk: Not classified as flammable or explosive, though fine dust can present ignition risk in confined spaces
Thermal Decomposition: Produces hazardous and noxious gases; ensure proper ventilation after extinguishing a fire

Accidental Release Measures

Personal Precautions: Use appropriate personal protective equipment such as gloves, goggles, and respiratory protection to prevent direct contact and dust inhalation
Environmental Precautions: Prevent spillage from entering surface water drains; notify local environmental authorities if large contamination occurs
Cleanup Procedures: Collect spillage using a method that minimizes dust generation (e.g., damp sweeping, vacuuming with HEPA filter); dispose in accordance with local regulations
Decontamination: Clean area thoroughly using water and detergent after initial dry cleanup
Emergency Procedures: Evacuate immediate area if airborne dust concentrations develop, especially in confined or poorly ventilated areas

Handling and Storage

Handling: Maintain good industrial hygiene; avoid breathing dust and contact with skin and eyes; wash hands thoroughly after handling; use in well-ventilated areas
Storage: Store in tightly closed containers, in a dry, well-ventilated place, away from direct sunlight and incompatible chemicals such as strong strong acids, bases or oxidizers
Temperature Sensitivity: Stable under normal room temperature and humidity ranges; avoid excessive heat
Special Requirements: Keep away from food, drink, and animal feeding areas; label containers properly for identification and hazard awareness
Incompatibilities: Strong oxidizing agents and bases may promote degradation or hazardous reactions

Exposure Controls and Personal Protection

Exposure Limits: No specific workplace exposure limits defined; handle as nuisance particulate in absence of data
Engineering Controls: Provide local exhaust ventilation to control airborne dust; ensure general area ventilation meets workplace standards
Personal Protective Equipment: Use chemical-resistant gloves, safety goggles, dust mask or respirator if airborne dust is present
Hygiene Measures: Prohibit eating, drinking, or smoking in handling area; wash thoroughly after operations
Environmental Controls: Prevent material from reaching drains or waterways by enforcing appropriate workplace controls

Physical and Chemical Properties

Appearance: White or near-white crystalline powder
Odor: No distinctive odor
Melting Point: 155–160°C
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not available
Solubility: Slightly soluble in water; more soluble in organic solvents such as ethanol, chloroform
Vapor Pressure: Not significant at room temperature
Density: Approximately 1.3 g/cm³
pH: Data not available (not relevant for solid form)

Stability and Reactivity

Chemical Stability: Stable under standard storage and handling conditions; avoid moisture and air exposure for prolonged periods
Reactivity: Non-reactive with most commonly encountered materials but reacts with strong oxidizers
Decomposition Products: Thermal decomposition yields toxic and irritating fumes including oxides of nitrogen, carbon monoxide, and carbon dioxide
Conditions to Avoid: Excessive heat, strong sunlight, sources of ignition, strong acids and bases
Polymerization: Product does not polymerize under normal conditions

Toxicological Information

Acute Toxicity: Oral LD50 in rats estimated at >2,000 mg/kg, indicating low acute toxicity; may cause minor symptoms such as headaches or nausea in exposed humans
Chronic Toxicity: No clear evidence of chronic toxicity in recommended use; possible mild effects on liver at high occupational exposure in laboratory animals
Skin Contact: Irritant potential low; allergic reactions occur rarely
Eye Contact: May cause mild, transient irritation
Inhalation: Dust inhalation could lead to mild irritation but lacks evidence for chronic respiratory effects
Carcinogenicity: Not classified as a known carcinogen by major regulatory agencies
Mutagenicity/Teratogenicity: Laboratory testing indicates no mutagenic or teratogenic risks in typical exposure scenarios

Ecological Information

Ecotoxicity: Not classified as hazardous for aquatic organisms in typical environmental concentrations, but avoid significant runoff
Persistence and Degradability: Product expected to biodegrade under certain conditions though rates remain unquantified
Bioaccumulation: Low potential for bioaccumulation
Mobility in Soil: Limited mobility due to low water solubility so risk of widespread aquatic contamination remains low
Other Adverse Effects: High concentration spills near water or food sources need addressing to prevent unintended long-term impacts on non-target species

Disposal Considerations

Product Disposal: Dispose of waste and residues in accordance with local, regional, or national regulations; incineration at licensed facility or chemical landfill recommended
Container Disposal: Rinse emptied packaging thoroughly before recycling or disposal; containers with significant residue require special handling
Environmental Precautions: Minimize waste by using product completely; do not discharge into sewer systems, surface water, or storm drains
Special Disposal Instructions: Consult with hazardous waste disposal specialists for large quantities

Transport Information

UN Number: Not assigned as non-hazardous for transport
Proper Shipping Name: Ethopabate
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Environmental Hazards During Transport: Avoid contact with food and feed in transit; ensure no leaks or spills during handling
Special Precautions: Handle containers to prevent breakage and uncontrolled release

Regulatory Information

Global Inventories: Listed on relevant chemical inventories where used as a feed additive
Regulation in Veterinary Use: Permitted as a coccidiostat in many jurisdictions under veterinary oversight
Labelling Requirements: Appropriate hazard labeling required for workplace containers in most countries
SARA Title III: Not regulated as a hazardous substance
Other Regulations: Follow national feed and agricultural chemical laws and workplace safety codes for transport, use, storage