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Name: Esomeprazole Magnesium Dihydrate
Chemical Formula: C34H36MgN6O18S3·2H2O
Synonyms: S-Omeprazole Magnesium Salt Dihydrate
Appearance: Almost white or slightly colored crystalline powder
Intended Use: Usually found in pharmaceuticals for reducing stomach acid
Odor: Odorless
Solubility: Soluble in water; more soluble in alkaline solutions
Main Hazards: Eye and skin irritation can arise from direct contact; dust inhalation can trigger respiratory irritation in sensitive individuals; not classified as carcinogenic or mutagenic
GHS Labels: Eye irritant; skin irritant
Routes of Exposure: Eyes, skin, inhalation, ingestion
Symptoms: Redness, itching, respiratory discomfort, or mild gastrointestinal disturbance if ingested in large amounts
Chemical Identity: Esomeprazole Magnesium Dihydrate
CAS Number: 217087-09-7
Concentration: Pure compound without known stabilizers, diluents, or excipients as a raw material
Inhalation: Move affected person to fresh air; medical attention should be sought if respiratory symptoms do not subside
Skin Contact: Rinse exposed area with plenty of water; remove contaminated clothing
Eye Contact: Rinse eyes with water for at least 15 minutes, avoiding rubbing; medical evaluation recommended for irritation
Ingestion: Rinse mouth; seek medical advice for persistent discomfort
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, or foam
Protective Equipment: Full protective gear and a self-contained breathing apparatus
Combustion Hazards: Oxides of carbon, nitrogen, sulfur, and magnesium may be released; dust can become combustible in high concentrations
Personal Protection: Use protective gloves, goggles, and a respirator if dusting occurs
Containment: Avoid dust formation; ventilate area
Cleanup: Sweep and scoop material into a labeled waste container; dampen to avoid dust
Disposal: Dispose of waste using a licensed facility; do not flush into drains
Handling: Limit dust generation; provide local exhaust ventilation; use protective equipment
Storage: Keep in tightly closed containers; store in a dry, cool environment away from strong oxidizers and direct sunlight
Other Considerations: Maintain good hygiene practices to reduce accidental exposure
Exposure Limits: None established for esomeprazole magnesium dihydrate
Engineering Controls: Use local exhaust to minimize airborne dust
Protective Equipment: Gloves, safety glasses, lab coat; respiratory protection in poorly ventilated settings
Hygiene: Wash hands thoroughly after handling; avoid eating, drinking, or smoking where product is used
Physical State: Crystalline solid
Color: Almost white to slightly colored
Melting Point: Decomposes before melting
Boiling Point: Not applicable
Solubility: Readily soluble in water and moderately in ethanol
pH (1% solution): Slightly alkaline
Odor: Odorless
Bulk Density: Moderate, non-dusting under normal conditions
Chemical Stability: Stable under recommended conditions; moisture-sensitive, degrades at elevated temperature or light
Incompatible Materials: Strong acids and oxidizing agents
Hazardous Decomposition: May emit toxic gases like carbon monoxide, nitrogen oxides, and sulfur oxides at high temperatures
Acute Toxicity: Low oral toxicity based on pharmacological use; accidental large ingestion may upset stomach
Chronic Exposure: Not linked to chronic effects at therapeutic doses; poorly studied in occupational settings
Irritation: Skin or eye exposure can cause mild irritation; inhalation of dust can irritate respiratory mucosa
Sensitization: Not expected to cause allergic reactions
Cancer Risk: No evidence of carcinogenicity in regulated databases
Aquatic Toxicity: Limited data, but pharmaceuticals often disrupt aquatic life if released in excess
Persistence: Chemically stable, may persist in the environment; degrades slowly under natural conditions
Bioaccumulation: Not expected to significantly bioaccumulate
Other Effects: Responsible handling reduces environmental contamination risks
Waste Disposal: Treat as hazardous pharmaceutical waste; incineration at a qualified facility preferred
Container Disposal: Rinse thoroughly before recycling or disposal
Environmental Precautions: Do not let material enter surface water or sewer systems without proper treatment
UN Classification: Not classified as hazardous for transport by land, air, or sea
Labeling: Standard chemical labeling recommended
Precautions: Prevent container damage and moisture exposure during transit
Global Inventories: Listed in some pharmaceutical regulatory agency databases
Occupational Exposure: No specific exposure limit values by OSHA, ACGIH, NIOSH, or EU authorities
Health and Environment: Subject to regulation under pharmaceutical and chemical legislation
Worker Safety: Use guided by national occupational health standards
