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Eprinomectin Material Safety Data Sheet (MSDS)

Identification

Product Name: Eprinomectin
Chemical Formula: C50H75NO14
Synonyms: Eprinex, Eprecis, E-Pour, Ivomec-Eprinex
CAS Number: 123997-26-2
Recommended Use: Veterinary endectocide for parasite control in cattle, sheep, goats
Supplier Information: Manufacturer’s name, address, and emergency phone number usually available on packaging

Hazard Identification

Classification: Skin sensitization (Category 1), Acute aquatic toxicity (Category 1), Chronic aquatic toxicity (Category 1), not classified as carcinogenic
Warning Symbols: GHS07 (exclamation mark), GHS09 (environmental hazard)
Signal Word: Warning
Hazard Statements: May cause an allergic skin reaction, extremely toxic to aquatic life with long-lasting effects, can irritate eyes and skin, toxic if swallowed or inhaled in large amounts
Precautionary Statements: Avoid breathing dust or fume, avoid release to the environment, wear protective gloves and eye protection, wash hands thoroughly after handling, do not eat or drink when using this product

Composition / Information on Ingredients

Eprinomectin: 0.5% to 5% weight, active ingredient
Solvent (e.g., Propylene glycol): up to 95% weight, carrier substance
Surfactants and emulsifiers: up to 5% weight, needed for consistency
Other ingredients: proprietary, may include preservatives or pH adjusters

First Aid Measures

Inhalation: Move to fresh air, keep person at rest, seek medical advice if symptoms persist like difficulty breathing
Skin contact: Remove contaminated clothing, rinse skin with soap and plenty of water, seek medical attention for irritation or rash
Eye contact: Rinse eye cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing and consult a specialist
Ingestion: Rinse mouth, seek immediate medical attention, do not induce vomiting except on physician’s advice
Note to Physician: No specific antidote recognized, treat symptomatically

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam, water spray
Unsuitable Extinguishing Media: Avoid using high-pressure water jets
Specific Hazards: Combustion releases toxic fumes such as carbon monoxide, nitrogen oxides, hydrogen chloride
Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Additional Advice: Prevent runoff from entering drains and waterways

Accidental Release Measures

Personal Precautions: Use proper ventilation, avoid contact with skin and eyes, wear gloves and protective clothing
Environmental Precautions: Prevent spills from reaching drains, soil, or natural water bodies; contains substances highly toxic to aquatic life
Methods for Cleanup: Absorb with inert material (sand, earth), collect and dispose of according to local regulations, clean contaminated area thoroughly, ventilate area during and after cleanup

Handling and Storage

Handling: Use only in well-ventilated settings, avoid inhalation of vapor or mist, prevent contact with skin and eyes, keep away from food and drink during use
Storage: Store in a tightly closed container, keep in a cool (15-30°C), dry, and well-ventilated place, protect from direct sunlight and incompatible materials such as strong acids and oxidizers, store away from animal or human foodstuffs

Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation or general room ventilation to minimize vapors
Personal Protective Equipment (PPE): Chemical-resistant gloves, protective clothing, safety goggles, face mask (if working with concentrated vapor), use respirator if exposure limits are exceeded
Hygiene Measures: Wash hands after use and before eating or drinking, do not smoke during handling, remove contaminated clothing before entering rest areas

Physical and Chemical Properties

Appearance: Clear to pale yellow liquid or viscous solution
Odor: Slight, medicinal or chemical smell
Melting Point: Not applicable (liquid product)
Boiling Point: Greater than 250°C (varies by solvent)
Solubility: Insoluble in water, soluble in organic solvents such as methanol and ethanol
Vapor Pressure: Very low at room temperature
pH: Neutral to slightly acidic, depending on formulation
Specific Gravity: About 1.0 - 1.1 (varies with concentration)
Flash Point: Over 100°C
Evaporation Rate: Slow

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Does not react under normal use
Conditions to Avoid: Heat, direct sunlight, contact with strong acids, oxidants, or bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides formed under fire conditions
Incompatible Materials: Strong acids, bases, and oxidizers can cause degradation

Toxicological Information

Acute Toxicity: Oral LD50 in rats around 50-100 mg/kg; may cause nausea or toxicity if swallowed
Skin Contact: May cause irritation or allergic reaction in sensitive individuals
Eye Contact: Irritation, redness, tearing possible
Chronic Effects: Prolonged or repeated skin exposure can cause sensitization
Carcinogenicity: No evidence found in animal studies of carcinogenic effect
Target Organs: Central nervous system, liver, gastrointestinal tract with significant exposure
Symptoms of Exposure: Dizziness, nausea, vomiting, headache, skin rash, eye irritation

Ecological Information

Toxicity: Extremely toxic to aquatic organisms (fish, invertebrates, algae)
Persistence and Degradability: Moderately persistent in environment, not rapidly biodegradable
Bioaccumulative Potential: Can bioaccumulate in aquatic organisms
Mobility in Soil: Low mobility due to high affinity for soils and sediments
Other Ecological Effects: Can disrupt invertebrate populations in aquatic ecosystems, runoff or improper disposal threatens water quality

Disposal Considerations

Waste Treatment Methods: Dispose as hazardous waste following local, national, and federal regulations
Contaminated Packaging: Triple rinse empty containers, puncture and dispose in licensed facility
Do Not: Dump product or rinsate into sewers, waterways, or drains
Recommended Disposal: Incineration in authorized plants or approved landfill, never reuse empty containers for other purposes

Transport Information

UN Number: 3082 (for large quantities)
Proper Shipping Name: Environmentally hazardous substance, liquid, n.o.s. (Eprinomectin)
Transport Hazard Class: 9 (Miscellaneous hazardous material)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions: Avoid release during transport, label clearly as hazardous and environmentally toxic, follow local and international transport regulations (ADR/RID/IMDG/ICAO/IATA)

Regulatory Information

Label Elements: GHS/CLP-compliant warnings and hazard pictograms
EU Regulations: Classified as dangerous for the environment, requires authorization for use
U.S. Regulations: Listed under TSCA inventory, subject to FIFRA for pesticide use, OSHA regulated
Other Guidance: Must comply with all relevant international and local chemical safety acts, record-keeping for purchase, use, and disposal advised for regulatory compliance
Restrictions: Veterinary use only, off-label uses and non-target species not advised, not approved for direct human treatments