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Product Name: Enrofloxacin Hydrochloride
Chemical Formula: C19H23FN4O3•HCl
CAS Number: 112732-17-9
Synonyms: Enrofloxacin hydrochloride, Baytril hydrochloride salt
Recommended Use: Veterinary antibiotic, used primarily for bacterial infections in animals
Supplier Information: Manufacturer and distributor name, address, and contact number should be listed here
Emergency Number: Emergency contact specific to company or poison control center
Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Specific target organ toxicity – single exposure (Category 3)
GHS Label Elements: Signal word: Warning, Hazard pictograms: Exclamation mark
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause respiratory irritation, toxic to aquatic life
Precautionary Statements: Avoid breathing dust or fumes, wash hands thoroughly after handling, avoid release to the environment, wear protective gloves, clothing, and eye protection
Potential Health Effects: May cause eye, skin, and respiratory tract irritation; ingestion may impact liver and kidney function
Chemical Identity: Enrofloxacin Hydrochloride
Concentration: 100% or as specified on supplier documentation
Impurities/Additives: Minor process impurities below regulatory thresholds, typically not mentioned on datasheet unless relevant for safety
Molecular Weight: Approximately 405.9 g/mol
Hazard Components: Enrofloxacin hydrochloride as the sole active ingredient with noted toxicological concern
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, seek medical attention if irritation persists
Skin Contact: Remove contaminated clothing, wash affected area with soap and plenty of water, seek medical advice if irritation continues
Inhalation: Move victim to fresh air, keep at rest, seek medical attention if symptoms develop
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical advice
Most Important Symptoms/Effects: Eye irritation, skin redness and soreness, sore throat if inhaled, possible stomach discomfort if swallowed
Advice for Doctors: Provide supportive treatment, treat symptoms, no specific antidote known
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide (CO2), or foam as required for area
Hazards from Combustion: Emits toxic fumes of chlorine, nitrogen oxides, hydrogen fluoride, and carbon oxides in fire
Special Protective Equipment: Wear self-contained breathing apparatus, chemical-protective clothing, gloves, and face shield
Firefighter Advice: Use water spray to cool fire-exposed surfaces, avoid inhaling combustion products, contain runoff from fire control to prevent contamination of water sources
Personal Precautions: Evacuate unnecessary personnel, ventilate area, use personal protective equipment such as gloves, goggles, and dust mask
Environmental Measures: Prevent further leakage or spillage if safe to do so, do not allow entry into drains, soil, or waterways
Cleanup Methods: Sweep up and shovel spilled material, avoid creating dust, place into suitable labeled container for proper disposal
Decontamination: Wash spill site after material pickup is complete, ventilate area, dispose of residues in accordance with local regulations
Handling: Handle in well-ventilated areas, avoid contact with skin and eyes, avoid inhaling dust or vapor, use appropriate personal protective equipment, do not eat, drink or smoke during use
Storage: Keep container tightly closed, store in a cool, dry, and well-ventilated location, segregate from incompatible substances (acids, bases, oxidizers)
Incompatibilities: Store away from acids, alkalis, strong oxidizing agents, and moisture
General Hygiene: Wash hands thoroughly after handling, remove and wash contaminated clothing before reuse
Exposure Limits: No occupational exposure limit established, minimize dust generation
Engineering Controls: Local exhaust ventilation or general ventilation to control airborne dust
Personal Protective Equipment: Wear protective gloves, impervious clothing, safety goggles, and dust respirator if potential for high airborne concentrations exists
Hygiene Measures: Wash hands and face after handling and before breaks or eating, avoid contact with eyes and skin
Appearance: White to off-white crystalline powder
Odor: Odorless or slightly characteristic pharmaceutical odor
Odor Threshold: Not determined
pH: Data not readily available for solid formulation; solution pH slightly acidic
Melting Point/Freezing Point: Decomposes before melting, decomposition temperature above 200°C
Boiling Point/Range: Not applicable (decomposes before boiling)
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Non-flammable under normal conditions
Vapor Pressure: Negligible
Vapor Density: Not applicable
Solubility: Soluble in water, low solubility in organic solvents
Partition Coefficient (log Kow): Not determined
Autoignition Temperature: No data available
Decomposition Temperature: Above 200°C, may emit toxic fumes
Other Info: Stable under recommended storage conditions, avoid exposure to light and heat
Chemical Stability: Stable under recommended storage conditions, sensitive to moisture, avoid excessive heat
Reactivity: No known reactivity hazards under normal handling and storage
Possibility of Hazardous Reactions: May react with strong acids, strong bases, and oxidizers
Conditions to Avoid: Exposure to moisture and extreme heat
Incompatible Materials: Strong acids, strong alkalis, oxidizing agents
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, fluorine and carbon oxides under fire or extreme heat conditions
Acute Toxicity: Oral LD50 (rat) estimated above 2,000 mg/kg
Skin Corrosion/Irritation: Causes irritation with redness, dryness, and soreness
Eye Damage/Irritation: Causes serious eye irritation with possible damage to eye membranes
Respiratory Sensitization: Dust may cause throat and respiratory irritation
Germ Cell Mutagenicity: Not classified as mutagenic in in vivo studies
Carcinogenicity: No evidence of carcinogenicity in experimental animal studies
Reproductive Toxicity: Adverse effects on developing fetus observed in animal studies at high doses
Specific Target Organ Toxicity – Single Exposure: May cause respiratory irritation, dizziness, headache, and nausea
Repeated Exposure: Potential to cause liver and kidney effects at high, repeated doses
Medical Conditions Aggravated: Individuals with allergies or pre-existing respiratory conditions may experience increased sensitivity
Ecotoxicity: Harmful to aquatic life with long lasting effects, LC50 values for fish (zebra danio) between 12-30 mg/L
Persistence and Degradability: Not readily biodegradable, persistent in the environment
Bioaccumulation: Low potential based on partition coefficient, bioaccumulation factor below significant concern
Mobility in Soil: Moderate mobility in soil, risk of groundwater contamination if not contained
Other Adverse Effects: May disrupt aquatic microbial communities, potentially impacting wastewater treatment
Safe Handling of Waste: Do not discharge to sewer or environment, prevent contamination of water sources
Disposal Methods: Collect waste in clearly labeled, sealed containers, dispose of in compliance with local, regional, and national regulations
Incineration: Preferred method for destruction under controlled conditions at permitted facility
Contaminated Packaging: Treat empty containers as hazardous, do not reuse, ensure complete decontamination or professional disposal
Special Instructions: Consult local hazardous waste disposal authority for guidance, avoid landfill whenever possible
UN Number: Not regulated as a dangerous good by transport authorities
Proper Shipping Name: Enrofloxacin hydrochloride, not classified as hazardous for transportation
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Environmental Hazards: Not classed as marine pollutant under IMDG
Special Precautions: Secure packaging to avoid spillage and minimize dust release, keep away from food and feedstuffs
ADR/RID, IATA/ICAO, IMDG Status: Not subject to transport regulation
US Regulations: Not listed as a hazardous substance under CERCLA, SARA, or TSCA, prescription drug under FDA veterinary regulations
EU Regulations: Classified according to Regulation (EC) No. 1272/2008 (GHS); veterinary use only, not permitted for use in food-producing animals in some regions
International Inventories: Listed or exempted in local chemical inventories (consult supplier for confirmation)
Workplace Regulations: Use as directed under OSHA standards, local occupational health guidelines apply
Other Statements: Observe all industry, regional, national, international regulations applicable to veterinary pharmaceuticals and hazardous substances, including disposal and reporting requirements
