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Product Name: Emiglitate
Chemical Family: Synthetic organic compound
Recommended Use: Industrial chemical, research component, pharmaceutical intermediate
Manufacturer: Emiglitate Chemicals Ltd,
Contact Details: 24/7 Emergency Hotline: +1-800-555-4032
CAS Number: 146378-92-3
Synonyms: 3-(4-hydroxyphenyl)-2-methylpropanoic acid
Supplier Address: 21 Donnelly Ave, Sharon, CT 06069, USA
Email for Inquiries: techservice@emiglitatechem.com
Product Code: EMG-17-282
Revision Date: June 2024
GHS Classification: Acute toxicity (oral) category 4, Eye irritation category 2A, Skin irritation category 2
Signal Word: Warning
Hazard Statements: Harmful if swallowed, Causes skin irritation, Causes serious eye irritation
Precautionary Statements: Wear protective gloves, Wear eye protection, Avoid contact with skin and eyes, Wash thoroughly after handling
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Potential Health Effects: Nausea, dizziness, skin redness, persistent eye watering, respiratory discomfort
Target Organs: Eyes, skin, oral mucosa
Pictograms: Exclamation mark
Substance: Emiglitate
Common Name: Emiglitate
CAS Number: 146378-92-3
Purity: >98%
Impurities: None expected in significant concentrations
Additives: No stabilizers present
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, seek immediate medical attention if pain persists
Skin Contact: Remove contaminated clothing, instantly wash skin with soap and plenty of water, do not reuse clothing until laundered
Inhalation: Move person to fresh air, keep comfortable for breathing, call a poison center or physician if symptoms occur
Ingestion: Rinse mouth with water, do not induce vomiting unless told by medical professional, seek medical help promptly
Symptoms to Watch For: Persistent irritation, burning, wheezing, headache, upset stomach
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide (CO2), foam
Unsuitable Extinguishing Media: Strong water jet
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, organic vapors
Protective Equipment: Full protective gear and self-contained breathing apparatus
Fire/Explosion Hazards: Emits toxic fumes if burned, possible formation of flammable dust-air mixtures
Special Fire Fighting Instructions: Evacuate area, keep containers cool with water spray from a safe distance, prevent run-off water from entering drains
Personal Precautions: Avoid contact with skin, eyes, and clothing, ventilate area, use personal protective equipment
Environmental Precautions: Prevent further leakage or spillage if safe, do not let product enter drains, soil, or waterways
Methods for Clean-Up: Collect spilled material using non-sparking tools, place in a suitable container for disposal, wash remaining area with soap and water
Protective Measures: Isolate area, keep unauthorized people away, report large spills to emergency services
Handling: Wear appropriate personal protection, minimize the generation and accumulation of dust, avoid contact with eyes, skin, clothing, and inhalation of dust or vapors, work in a well-ventilated place
Storage Conditions: Store tightly closed in original container, in a cool, dry, well-ventilated area away from direct sunlight, sources of ignition, and incompatible substances such as strong bases and oxidizers
Compatibility: Incompatible with strong acids, alkalis, and oxidizing agents
Special Rules: Keep clearly labeled, do not store near food or beverages, regularly inspect containers for damage
Occupational Exposure Limits: No ACGIH or OSHA thresholds established for Emiglitate
Engineering Controls: Use laboratory fume hood or local exhaust ventilation, provide eyewash facilities and safety shower
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety glasses with side shields, lab coat, suitable respirator if exposure exceeds limits or dust is generated
Hygiene Measures: Wash hands before eating or drinking, do not smoke in work areas, remove contaminated clothing
Environmental Controls: Use containment to prevent releases, treat waste according to procedures
Appearance: White to off-white crystalline powder
Odor: Very faint, slightly aromatic
Odor Threshold: Not established
pH (1% solution): 5.5–7.0
Melting Point/Freezing Point: 136–138°C
Boiling Point: Not applicable, decomposes
Flash Point: >200°C (closed cup)
Evaporation Rate: Not applicable
Flammability: Non-flammable (solid form)
Explosion Properties: Dust may form explosive mixtures with air
Vapor Pressure: Negligible
Vapor Density: Not applicable
Relative Density: 1.15–1.17 g/cm³
Solubility: Moderately soluble in water, freely soluble in ethanol and DMSO
Partition Coefficient (log Kow): 1.7
Auto-ignition Temperature: No data
Decomposition Temperature: Above 160°C
Viscosity: Not applicable
Chemical Stability: Stable at room temperature and under recommended storage conditions
Reactivity: Not reactive under normal conditions of use
Hazardous Reactions: Reacts with strong acids or bases, may generate heat and hazardous gases
Conditions to Avoid: Excessive heat, exposure to moisture or direct sunlight, dust formation
Incompatible Materials: Strong oxidizers, reducing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, various organic by-products
Acute Toxicity: Oral LD50 (rat): ~500 mg/kg
Acute Effects: Irritation of eyes, skin, and upper respiratory system
Chronic Effects: No data from long-term repeated exposure
Sensitization: Not expected based on available data
Mutagenicity: No evidence from Ames or micronucleus assays
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Reproductive Toxicity: No known adverse effect on fertility or development
Routes of Entry: Inhalation, ingestion, dermal, ocular
Target Organ Effects: Mildly irritating to mucous membranes and skin
Ecotoxicity: Toxicity to aquatic organisms (Daphnia EC50 72hr): 35 mg/L; Fish LC50 96hr: 45 mg/L
Persistence and Degradability: Expected to biodegrade in soil and water, half-life estimated at several weeks
Potential for Bioaccumulation: Log Kow of 1.7 suggests low risk of accumulation in organisms
Mobility in Soil: Moderate mobility due to partial solubility in water
Other Adverse Effects: May cause transient effects on sewage bacteria in large spills
Waste Disposal Methods: Dispose of unused material and contaminated packaging through licensed chemical waste contractor, incineration preferred
Contaminated Packaging: Triple rinse containers before recycling or disposal, follow local and national regulations
Environmental Precautions: Prevent entry into drains, ground, or surface water
Special Instructions: Do not attempt to treat waste by dilution, mixing, or chemical neutralization outside controlled waste facility
UN Number: Not regulated for transport according to ADR/RID, IMDG, or IATA
Proper Shipping Name: Emiglitate
Transport Hazard Class: Not hazardous
Packing Group: Not assigned
Environmental Hazards: None known
Transport in Bulk: Not subject to MARPOL Annex II or IBC code
Special Transport Precautions: Avoid extremes of heat, moisture, vibration during shipment
TSCA Status: Listed
DSL/NDSL (Canada): Listed
EINECS/ELINCS (Europe): Complies
OSHA Regulatory Status: Hazardous, see hazard section
SARA Title III: Not subject to reporting under SARA 302, 304, 311, 312, or 313
REACH Registration: Included in list of registered substances
Relevant Labeling: GHS, WHMIS, OSHA HCS 2012 compliant
Other Regulations: Not regulated under Clean Air Act, Clean Water Act, or as a drug/chemical of concern by DEA
Product for Industrial/Research Use Only: Not intended for direct food, drug, or household use
