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Material Safety Data Sheet: Dodecanoyl Chloride

Identification

Product Name: Dodecanoyl Chloride
Chemical Formula: C12H23ClO
CAS Number: 112-16-3
Synonyms: Lauryl Chloride, Lauroyl Chloride
Recommended Use: Intermediate for organic synthesis, used in surfactant manufacture, and chemical research
Supplier Details: Chemical manufacturer and distributor information, including address and emergency telephone number for rapid contact in emergencies

Hazard Identification

Classification: Corrosive to skin and eyes, respiratory and skin sensitizer, hazardous if inhaled, causes severe burns
GHS Labels: Corrosive (GHS05), Acute Toxicity (GHS06)
Hazard Statements: Causes serious skin burns and eye damage, toxic if inhaled, harmful if swallowed, may cause respiratory irritation
Precautionary Statements: Wear protective gloves, protective clothing, eye and face protection, avoid breathing vapors, use only in well-ventilated areas, wash thoroughly after handling

Composition / Information on Ingredients

Chemical Identity: Dodecanoyl Chloride
Concentration: ≥ 98%
Impurities: May contain very small amounts of related acid chlorides and residual solvents from synthesis

First Aid Measures

Inhalation: Move individual outdoors to fresh air, keep person calm and warm, seek immediate medical attention if symptoms persist such as coughing or shortness of breath
Skin Contact: Remove contaminated clothing, rinse skin with flowing water for at least 15 minutes, obtain medical help, do not neutralize the chemical on the skin
Eye Contact: Remove contact lenses, flush eyes with clean, flowing water for at least 15 minutes, prioritize getting the person to an eye specialist
Ingestion: Rinse mouth, do not induce vomiting, never give anything by mouth to someone losing consciousness, get medical attention without delay

Fire-Fighting Measures

Suitable Extinguishing Media: Dry powder, carbon dioxide, foam for large fires, avoid using water jets directly due to risk of violent reaction with water
Hazards: Releases toxic and corrosive gases such as hydrogen chloride and carbon monoxide under fire conditions
Special Precautions: Fire-fighters must wear full protective gear and self-contained breathing apparatus to deal with fumes, keep containers cool by spraying open flames with water spray from a safe distance

Accidental Release Measures

Personal Precautions: Wear suitable protective clothing, gloves, and chemical splash goggles, work in well-ventilated spaces or a fume hood
Spill Cleanup: Absorb with inert material like dry sand or earth, avoid using water directly, collect residue in sealable containers for disposal, ventilate the area
Environmental Precautions: Block entry to sewers, surface waters, or soil, notify authorities in case of large spills or contamination risks

Handling and Storage

Handling: Use with adequate ventilation, do not breathe vapors, employ local exhaust systems in enclosed areas, never eat, drink, or smoke during use
Storage: Store tightly closed in cool, dry, well-ventilated area away from moisture, acids, bases, alcohols, amines, and strong oxidizing agents, label containers clearly, use corrosion-resistant shelving

Exposure Controls and Personal Protection

Engineering Controls: Fume hoods, local exhaust ventilation, emergency eyewash stations, hand wash facilities
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), splash-proof safety goggles, face shield, long-sleeved lab coat, chemical apron, suitable respiratory protection for airborne concentrations
Occupational Exposure Limits: No established exposure limits, minimize exposure as much as possible

Physical and Chemical Properties

Appearance: Clear to yellowish liquid
Odor: Pungent, irritating odor
Melting Point: 10-13°C
Boiling Point: 292°C
Density: 0.94–0.96 g/cm³ at 20°C
Solubility: Reacts violently with water, miscible with most organic solvents
Vapor Pressure: Low at room temperature
pH: Not applicable (hydrolyzes in water)

Stability and Reactivity

Chemical Stability: Stable when stored dry and under recommended conditions
Conditions to Avoid: Exposure to moisture, strong oxidizers, bases, alcohols, amines
Hazardous Decomposition: Hydrogen chloride gas, carbon oxides, phosgene
Hazardous Reactions: Exothermic reaction with water liberating hydrochloric acid and heat

Toxicological Information

Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Effects: Severe burns to skin and mucous membranes, eye damage, respiratory tract irritation
Chronic Effects: Risk of long-term skin and respiratory sensitization, potential development of asthma-like symptoms
Toxicity Data: LD50 (oral, rat): Data limited, but classified as harmful if swallowed
Symptoms: Burning sensation, coughing, shortness of breath, ulceration of exposed tissues

Ecological Information

Ecotoxicity: Harmful to aquatic organisms as hydrolysis products persist and acidify water
Persistence and Degradability: Reacts rapidly with water forming lauric acid and hydrochloric acid, both capable of impacting local pH and posing risk to aquatic life
Bioaccumulation Potential: Low, but precaution advised due to toxicity of hydrolysis products
Mobility in Soil: High, due to water reactivity, can migrate through moist soils as acid forms
Special Notes: Avoid release into the environment, never pour down drains or into watercourses

Disposal Considerations

Methods: Send to licensed hazardous waste treatment facility, do not mix with household waste, neutralize and dispose under expert supervision, avoid contact with water during disposal process
Contaminated Packaging: Rinse thoroughly with an approved neutralizing agent inside specialized facilities, dispose of packaging through hazardous waste channels

Transport Information

UN Number: UN 1758
Proper Shipping Name: Chlorinated fatty acid derivative, corrosive, n.o.s. (Dodecanoyl Chloride)
Hazard Class: 8 (Corrosive substances)
Packing Group: II
Transport Labels: Corrosive label required, keep away from incompatible substances, ship in tightly sealed containers compliant with transit regulation for hazardous materials

Regulatory Information

OSHA: Covered under Hazard Communication Standard, considered hazardous
TSCA: Listed
REACH: Registered, subject to special handling stipulations in the EU
Other Regulations: Complies with applicable national and local environmental, safety, and health requirements in major industrial regions; detailed procedures for notification of accidental releases required in certain jurisdictions