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Product Name: Dinitrogen Tetroxide
Synonyms: Nitrogen Tetroxide, NTO
Chemical Formula: N2O4
CAS Number: 10544-72-6
Recommended Use: Used in rocket propellants, chemical synthesis, analytical reagent
Manufacturer: Refer to product supplier
Emergency Contact: Local emergency numbers or national poison center
Address: Manufacturer’s facility or distribution site as listed on product label
Hazard Class: Acute Toxicity (Inhalation, Oral, Dermal), Corrosive to metals and skin, Oxidizing agent
Hazard Statements: Toxic if inhaled, causes severe skin burns and eye damage, may cause respiratory irritation, harmful if swallowed
Signal Word: Danger
GHS Classification: Acute Toxicity Category 2 (Inhalation), Skin Corrosion Category 1B, Specific Target Organ Toxicity (STOT) Category 3
Pictograms: Skull and crossbones, corrosion symbol, exclamation mark
Precautionary Statements: Avoid breathing vapors, wear protective gloves and eye/face protection, wash hands thoroughly after handling, use only outdoors or in a well-ventilated area, keep container tightly closed
Chemical Name: Dinitrogen Tetroxide
Synonyms: Nitrogen Tetroxide, NTO
Concentration: 100% (pure substance)
Impurities: Trace amounts of nitrogen dioxide may be present depending on storage and handling
Inhalation: Move victim to fresh air immediately, keep person calm and warm, seek medical attention right away, administer oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing, rinse affected skin with running water for at least 15 minutes, wash with soap and water, do not reuse contaminated clothing, get medical assistance
Eye Contact: Directly flush eyes with plenty of water for at least 15 minutes, lift eyelids occasionally, seek immediate medical attention
Ingestion: Never give anything by mouth to an unconscious person, do not induce vomiting, rinse mouth, seek immediate medical help
Main Symptoms and Effects: Respiratory irritation, difficulty breathing, skin burns, severe eye irritation, pulmonary edema (delayed)
Suitable Extinguishing Media: Flooding quantities of water, do not use dry chemical or carbon dioxide on this oxidizer
Unsuitable Extinguishing Media: Avoid chemicals that react with oxidizers (e.g. organic foams, dry powders)
Hazardous Combustion Products: Releases toxic nitrogen oxides, corrosive and irritating fumes
Specific Hazards in Fire: Strong oxidizer; intensifies fire, may react violently with many materials
Firefighting Instructions: Evacuate area, wear full protective gear including SCBA, cool containers from safe distance
Personal Precautions: Evacuate area, eliminate ignition sources, ventilate space, wear chemical splash suit, gloves, safety goggles, and SCBA
Environmental Precautions: Prevent release to waterways, soil, and drains
Cleanup Procedures: Stop source of leak if safe, absorb liquid with inert non-combustible absorbent, collect for disposal, flush residual with water while wearing protective equipment, ventilate area thoroughly
Disposal: Follow local hazardous waste regulations, do not mix with combustibles during cleanup
Handling: Use with strict chemical hygiene practices, avoid inhaling fumes, prevent contact with skin and eyes, use only in fume hood or with exhaust ventilation, do not handle near organic materials or flammable substances, transfer using corrosion-resistant equipment
Storage: Store in tightly sealed containers, keep away from reducing agents, metals, organics, acids, bases, store in cool, dry, well-ventilated area away from sunlight and incompatible materials, regularly inspect containers for corrosion or leaks, label storage area clearly as toxic, oxidizer, and corrosive hazard
Occupational Exposure Limits: OSHA PEL (TWA) 0.2 ppm; ACGIH TLV 0.2 ppm (0.76 mg/m3), STEL 1 ppm (3.6 mg/m3)
Engineering Controls: Local exhaust ventilation, chemical fume hood, corrosion-resistant equipment, leak detection and gas monitoring
Personal Protective Equipment: Self-contained breathing apparatus for high concentrations, full chemical-resistant suit, nitrile or neoprene gloves, safety goggles, face shield, protective boots
Respiratory Protection: Approved respirators for concentrations above allowable limits, escape masks for emergencies
Hygiene Measures: Do not eat, drink, or smoke in work area, wash hands thoroughly after handling, remove contaminated clothing immediately
Appearance: Colorless to reddish-brown liquid or gas (depending on temperature)
Odor: Acrid, sharp, irritating
Molecular Weight: 92.01 g/mol
Melting Point: -11°C (12°F)
Boiling Point: 21°C (69.8°F)
Solubility: Soluble in water, reacts to form nitric and nitrous acid
Vapor Pressure: 36 kPa at 20°C
Density: 1.45 g/cm3 at 15°C
pH: Not applicable (reacts with water)
Partition Coefficient (octanol/water): Not available
Flash Point: Not flammable
Oxidizing Properties: Strong oxidizer
Chemical Stability: Stable at ambient temperatures in airtight containers
Reactivity: Reacts vigorously with organic materials, reducing agents, metals, strong bases, ammonia, combustibles
Hazardous Reactions: May cause explosion or fire on contact with organics or certain metals, forms corrosive gases with water
Hazardous Decomposition: Nitrogen oxides (NO, NO2) release in decomposition or fire
Conditions to Avoid: Contact with incompatible materials, heat, sunlight, moisture
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Effects: Severe respiratory irritation, difficult breathing, pulmonary edema, burns on skin and mucous membranes, eye damage
Chronic Effects: Chronic respiratory problems, possibly fatal lung inflammation, sensitization possible
LD50 (Inhalation): 88 ppm (rat, 4 hours)
Symptoms: Shortness of breath, chest pain, coughing, headache, skin redness or burns, impaired vision
Carcinogenicity: Not listed by IARC, NTP, or OSHA as carcinogen
Mutagenicity and Reproductive Toxicity: No conclusive evidence, but avoid chronic exposure due to severe acute effects
Ecotoxicity: Harmful to aquatic organisms, can cause damage to aquatic life at low concentrations
Persistence and Degradability: Reacts rapidly with water, hydrolyzes to nitric and nitrous acids, which acidify water and soil
Bioaccumulative Potential: Low, due to rapid hydrolysis and conversion to simple nitrogen oxides and acids
Mobility in Soil: Highly mobile, reacts in moist air and water, may contaminate ground and surface waters
Other Adverse Effects: Contributes to acidification of aquatic and terrestrial environments, involvement in formation of acid rain from atmospheric release
Waste Disposal: Dispose of using licensed hazardous waste collectors, never pour to sewer, landfill, or regular trash, neutralization may be performed by trained personnel at approved facilities only, follow national and international hazardous waste regulations
Contaminated Packaging: Treat as hazardous waste, decontaminate thoroughly before disposal, send to approved drum reconditioning or hazardous waste incineration facility
UN Number: UN1067
Proper Shipping Name: Dinitrogen Tetroxide, liquefied
Hazard Class: 2.3 (Toxic Gas), 5.1 (Oxidizing agent)
Packing Group: I
Label Requirements: Toxic gas, oxidizer
Special Provisions: Keep away from heat, direct sunlight, and incompatible substances during transport, ensure all containers are leak-tight and properly labeled, emergency response guide available during transit
Marine Pollutant: Yes; dangerous for water shipment
Transport Regulations: Subject to regulation under IATA, IMDG, and DOT for hazardous materials
OSHA: Hazardous chemical under OSHA Hazard Communication Standard
TSCA: Listed on the US Toxic Substances Control Act (TSCA) Inventory
SARA: Title III Section 302 extremely hazardous substance, Section 313 reportable toxic chemical
EPCRA: Reportable Quantity: 10 lbs (4.54 kg)
CERCLA: Not specifically listed, but reportable due to hazardous nature
Other Regulations: Subject to local, state, national, and international regulations for hazardous, toxic and oxidizing substances; use personal protective and environmental controls as defined in each applicable region
