© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Chemical Name: Dimethyl 4,4'-Biphenyldicarboxylate
CAS Number: 3296-90-0
Synonyms: Dimethyl biphenyl-4,4'-dicarboxylate, 4,4'-Biphenyldicarboxylic acid dimethyl ester
Product Use: Intermediate for organic synthesis, plastics manufacturing, chemical research
Supplier/manufacturer: Refer to local distributor or manufacturer for details
Emergency phone number: Available through local hazardous materials response lines or company emergency contact
Classification: Not classified as hazardous according to GHS criteria
Labels Required: None under normal usage, monitor for dust generation
Hazards: Dust may cause slight eye, respiratory, or skin irritation. No chronic health effects documented.
Signal Word: None
Pictograms: None
Precautionary Statements: Avoid breathing dust, maintain clean workspace, wash thoroughly after handling solids
Emergency Overview: Fine particulate may form combustible dust clouds if dispersed in air
Chemical Identity: Dimethyl 4,4'-Biphenyldicarboxylate
Concentration: >98% by weight
Impurities: Residual solvents, trace organic byproducts (<2%)
Molecular Formula: C16H14O4
Molecular Weight: 270.28 g/mol
Inhalation: Remove person to fresh air, monitor breathing, offer symptomatic support if coughing continues
Skin Contact: Remove contaminated clothing, wash skin under running water with soap
Eye Contact: Rinse with water for at least 15 minutes; seek medical attention if irritation develops
Ingestion: Rinse mouth with water, provide water to drink, seek medical attention if discomfort or symptoms occur
Note for Physicians: Treat symptomatically, no specific antidote reported
Extinguishing Media: Use water spray, CO2, dry chemical, foam to extinguish flames
Unsuitable Media: Direct water jet may spread powder
Specific Hazards: Dust can form explosive mixtures with air; combustion releases carbon monoxide, carbon dioxide, toxic gases
Firefighter Protection: Self-contained breathing apparatus, full protective gear
Special Procedures: Move container from fire area if safe; cool surroundings with water
Personal Precautions: Evacuate area, avoid dust inhalation, ventilate enclosed spaces, use PPE including dust mask, gloves
Methods for Cleanup: Collect spilled solid using non-sparking tools, sweep gently; avoid raising dust.
Environmental Precautions: Prevent spill from entering drains, surface water, or soil
Waste Disposal: Store in suitable containers for disposal via licensed waste contractor
Safe Handling: Work away from ignition sources, use local exhaust ventilation, avoid creating dust clouds, wear protective clothing and eye shield
Storage Requirements: Store tightly closed in dry, cool, well-ventilated area, away from incompatible materials (strong oxidizers)
Incompatibilities: Keep away from acids, bases, and oxidizing agents
Hygiene Practices: Wash hands after use, do not eat or drink near material
Occupational Exposure Limits: No specific exposure limits for this compound, treat as nuisance dust (10 mg/m³ total dust, 3 mg/m³ respirable, ACGIH TLV)
Engineering Controls: Local exhaust, mechanical ventilation, dust collection systems
Personal Protective Equipment:
Respiratory: NIOSH-approved dust mask or respirator for concentrations above limits
Gloves: Chemical-resistant or disposable gloves
Eyes: Safety glasses with side shields or goggles
Skin: Lab coat or chemical apron to avoid contamination
Environmental Controls: Use in well-ventilated areas, prevent release into environment
Appearance: White crystalline powder
Odor: Odorless or faint aromatic
Odor Threshold: Not determined
pH: Not available (insoluble in water)
Melting Point: 233–236°C
Boiling Point: 410–415°C (decomposes)
Flash Point: >235°C
Flammability: May form combustible dust clouds
Vapor Pressure: Negligible
Solubility: Poorly soluble in water, soluble in organic solvents (methanol, ethanol, acetone, ether)
Partition Coefficient (log Kow): Estimated 3.1–3.3
Density: Approx. 1.26–1.30 g/cm³
Viscosity: Not applicable
Evaporation Rate: Not applicable (non-volatile solid)
Chemical Stability: Stable under normal use and storage conditions
Reactivity: No dangerous reactions under expected storage and handling conditions
Conditions to Avoid: High temperatures, sources of ignition, strong oxidants
Incompatible Materials: Strong acids, alkalis, oxidizing agents
Hazardous Decomposition Products: Burning produces irritating fumes, carbon monoxide, carbon dioxide, minor organic byproducts
Polymerization: Product does not polymerize spontaneously
Acute Toxicity: Low oral toxicity (estimated LD50 oral rat >2000 mg/kg); no significant dermal or inhalation data
Skin Corrosion/Irritation: Mild transient irritation may occur
Eye Damage/Irritation: Dust could irritate eyes mechanically
Respiratory Sensitization: Not classified as a respiratory sensitizer, but dust could trigger minor irritation
Ingestion: No known systemic toxicity at low doses
Carcinogenicity: Not listed as carcinogen by IARC, NTP, ACGIH, OSHA
Mutagenicity: No data indicating mutagenic potential
Reproductive Toxicity: No documented reproductive or developmental toxicity
Repeated Dose Toxicity: Not identified
Ecotoxicity: Not expected to be acutely toxic to aquatic organisms; low solubility limits environmental exposure
Persistence and Degradability: Biodegradation may take significant time, persistent in environment
Bioaccumulative Potential: Moderate potential due to insolubility and log Kow >3
Mobility in Soil: Low mobility, binds to sediment
Other Adverse Effects: No significant ozone depletion, greenhouse gas, or environmental hazards
Waste Treatment Methods: Disposal via licensed hazardous waste processor
Disposal Containers: Use lined or tightly sealed containers to prevent dust or powder escape
Incineration: Permitted in approved facilities; incinerate according to regional or national guidelines
Regulatory Controls: Dispose in line with local, state, and national regulations
Unused Material: Store as hazardous waste pending qualified disposal
UN Number: Not regulated for transport under UN Recommendations
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified as dangerous
Packing Group: Not assigned
Marine Pollutant: Not expected
Special Precautions: Prevent container damage, keep containers closed during transit, label as dust-producing material if in bulk
Transport in Bulk: Avoid dispersion of dust; use appropriate containment practices
TSCA Inventory: Listed
REACH Registration: Consult latest ECHA updates for substance status inside the EU
OSHA Regulation: Not classified as hazardous
WHMIS Classification (Canada): Not controlled
Other Regulations: Not listed in California Proposition 65, not subject to specific US SARA Title III reporting
Labeling Requirements: Standard workplace chemical label indicating chemical name and hazard warnings if dust-producing
International Inventories: Included on many national inventories; verify compliance regionally
