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Product Name: Diclazuril
Chemical Name: 2,6-Dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2-yl)benzeneacetonitrile
CAS Number: 101831-37-2
Intended Uses: Anticoccidial agent in veterinary medicine for poultry and livestock
Manufacturing Company: Name and address provided on invoice and packaging
Telephone Number: Check label or packaging for emergency contact
Email for SDS Requests: Found on company website or packaging inserts
Synonyms: Diclazurilium, Coccidiostat, Veterinary anticoccidial
Recommended Restriction: Not for human medical use, recommended for professional and industrial handlers, veterinarian guidance advised
GHS Classification: Acute Toxicity (Oral) Category 4, Eye Irritation Category 2A
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes serious eye irritation, may cause respiratory irritation, not classified as flammable or explosive
Pictograms: Exclamation mark
Potential Health Hazards: Inhalation may cause respiratory tract irritation; skin or eye contact can result in temporary discomfort or irritation; repeated or prolonged exposure may increase sensitization risk
Environmental Hazards: Toxic to aquatic life with long-lasting effects, avoid contamination of water resources
Other Hazards: Not known to be carcinogenic, teratogenicity and mutagenicity not established but should not be assumed safe without precautions
Active Ingredient: Diclazuril
Concentration: Typically 98% or greater in technical grade, with the remainder composed of trace impurities and stabilizers
Impurities: Levels below 2%, exact nature depends on synthesis; does not contain known hazardous excipients at significant levels
Formulation Additives (If present): May contain bulking agents, carriers such as cornmeal or lactose for premixes
Physical Form: Fine powder or crystalline solid, varies with supplier
Molecular Formula: C17H9Cl3N4O2
Molecular Weight: 407.6 g/mol
Inhalation: Remove to fresh air and monitor breathing, seek medical attention if symptoms persist such as coughing or shortness of breath
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, seek medical help if irritation occurs
Eye Contact: Rinse cautiously with clean water for at least 15 minutes holding eyelids open, obtain medical aid if discomfort remains
Ingestion: Rinse mouth, do not induce vomiting unless instructed by a medical professional, seek immediate medical care and show label or SDS where possible
Recommended Medical Treatment: Symptomatic and supportive care, no known antidote
Self-Protection for First Aiders: Avoid direct contact, wear gloves and safety glasses
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, or foam
Unsuitable Extinguishing Media: High-pressure water jets may spread dust
Special Fire Hazards: Decomposes under high heat to form hazardous and irritating fumes, chlorine, nitrogen oxides, hydrogen chloride may evolve
Firefighter Protection: Wear self-contained breathing apparatus, full protective gear; avoid getting substance on skin or in eyes
Firefighting Tips: Contain runoff to prevent environmental contamination, use water spray to cool containers
Personal Precautions: Use protective gear (gloves, goggles, mask), avoid breathing dust, ventilate area well
Environmental Precautions: Prevent entry into drains, rivers, or soil; report major spills to authorities
Methods for Cleaning Up: Scoop up using non-sparking tools, avoid dust generation, place in labeled containers for proper waste management, wipe residues with damp cloth or absorbent material
Spill Disposal: Dispose in accordance with local regulations, do not allow material to contaminate groundwater or ecological systems
Safe Handling: Use in well-ventilated areas, minimize dust, wash hands thoroughly after use, do not eat or drink during use
Storage Conditions: Keep in tightly closed, labeled containers; store in a cool, dry place away from light, heat sources, and incompatible materials
Specific Storage Location: Locked chemical cabinet or storage room, keep out of reach of children and unauthorized persons
Incompatible Materials: Avoid exposure to strong oxidizing agents, acids, or bases that may lead to dangerous decomposition
Recommended Materials for Packaging: Polyethylene, glass, other suitable inert containers
Occupational Exposure Limits: No established threshold limit values for diclazuril, aim for minimal exposure based on general dust hazard recommendations
Engineering Controls: Provide exhaust ventilation or local fume extraction to control airborne particles
Personal Protection: Safety goggles, chemical-resistant gloves (nitrile or latex), dust mask or respirator (NIOSH-approved), long-sleeved clothing or protective apron
Work Practice Controls: Strict personal hygiene, change clothes if contaminated, regular workplace cleaning
Environmental Controls: Use containment to minimize release, monitor for dust and airborne contamination, avoid contamination of the environment during transfer and weighing
Appearance: White or off-white crystalline powder
Odor: Odorless or faint characteristic odor
pH (1% solution): Not data available, typically neutral
Melting Point/Freezing Point: 290-295°C (with decomposition)
Boiling Point: Not applicable under atmospheric pressure (decomposes)
Solubility: Slightly soluble in water, freely soluble in dimethyl sulfoxide, soluble in methanol and acetone
Vapor Pressure: Not volatile at ambient temperature
Density: About 1.6 g/cm3
Flash Point: Not relevant (not flammable)
Partition Coefficient (log Pow): 2.5 - 3.0
Explosive Properties: Not classified as explosive
Decomposition Temperature: Above 290°C (releases hazardous gases)
Chemical Stability: Stable under recommended storage conditions, sensitive to strong heat, light, and incompatible chemicals
Reactivity: No known dangerous reactivity under normal handling
Conditions to Avoid: Exposure to direct sunlight, open flames, high temperatures, moisture
Hazardous Decomposition Products: Hydrogen chloride, chlorine gas, nitrogen oxides, other harmful fumes at high temperature
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Polymerization: No hazardous polymerization expected
Acute Toxicity (Oral): LD50 (rat, oral) > 3,000 mg/kg
Acute Toxicity (Dermal): Not acutely toxic in animal tests
Skin Irritation: Mild irritation may occur after prolonged or repeated contact
Eye Irritation: Moderate irritation observed in laboratory animals
Inhalation Toxicity: No confirmed reports of significant toxicity, avoid inhalation of dust
Chronic Effects: Prolonged exposure not well studied, based on animal data, not anticipated to cause carcinogenic, mutagenic or reproductive toxic effects at low doses used for treatment in animals
Sensitization: Rare instances of allergy or skin sensitization
Other Data: No evidence of target organ toxicity at doses typically encountered in working conditions
Aquatic Toxicity: Toxic to fish and aquatic invertebrates; LC50 values in relevant species are < 10 mg/L
Persistence and Degradability: Slowly biodegradable in the environment, persistent in soils and sediment
Bioaccumulation: Potential to bioaccumulate in aquatic organisms is low to moderate
Mobility in Soil: Low mobility predicted due to low water solubility, strong adsorption to soil particles
Other Harmful Effects: Harmful to algae and plankton, ecosystem disruption possible in case of accidental large-scale release
Precaution: Keep away from natural water sources; follow established waste management protocols; avoid spread beyond controlled application zones
Waste Treatment Methods: Incineration under controlled conditions is preferred route; landfill only if approved for hazardous organics disposal
Packaging Disposal: Contaminated packaging should be cleaned before recycling where possible, empty containers completely before disposal, never reuse for food or drink
Regulations: Adhere to local and national hazardous waste regulations, inform authorities in case of large-scale disposal activities
Environmental Precautions: Do not release to surface water, sewer systems, or unprotected ground
User Responsibility: Responsibility for disposal lies with the owner/handler of unused product and packaging
UN Number: Not classified as dangerous goods under transportation regulations
UN Proper Shipping Name: Not dangerous for air, sea, or ground transport
Transport Hazard Class: Not regulated
Packing Group: Not assigned
Special Transport Precautions: Package securely to prevent leaks or spills, protect from humidity and rough handling in transit
Environmental Hazards: Avoid accidental release into waterways during loading and unloading
Transport Label: Standard labeling for chemical products, not subject to hazardous labeling
EU: Diclazuril listed on EC inventory; covered by CLP regulation for chemical classification and labeling
US: Not subject to stringent TSCA reporting as veterinary pharmaceutical, regulated under FDA and state laws
China: Registered as a veterinary drug with the Ministry of Agriculture
Other Jurisdictions: Regulatory status varies, check local and national authority listings for import, export, and handling guidelines
Workplace Regulations: OSHA or equivalent workplace guidelines may apply for general chemical safety, dust hazard, and personnel training
Product Restrictions: Use only in animal health applications, banned or restricted in certain countries for food-producing animals
