Chemical Name: Dibazol
Common Name: Bendazol
Chemical Formula: C8H10N4
Molecular Weight: 162.19 g/mol
Synonyms: 1-benzylbenzimidazole, Bendazolum
CAS Number: 86-92-0
Manufacturer: Manufacturer information needed based on supply source
Recommended Use: Vasodilator, pharmaceutical ingredient
Restrictions on Use: Not intended for use outside pharmaceutical manufacturing or scientific research settings
GHS Classification: Not classified as dangerous under GHS
Signal Word: Not applicable
Hazard Statements: May cause eye irritation, possibly mild skin irritation, could induce respiratory discomfort if excessively inhaled
Precautionary Statements: Avoid dust creation, do not eat or drink while handling, wash hands thoroughly after use
Physical Hazards: Not considered highly flammable or explosive under typical storage and handling conditions
Health Hazards: Prolonged exposure could cause mild irritation to eyes and mucous membranes, ingestion may lead to mild gastrointestinal symptoms
Environmental Hazards: Low risk to environment at normal concentrations, higher spills may pose local aquatic toxicity concerns
Substance: Dibazol (Bendazol)
Purity: Greater than 98%
Impurities: Other benzimidazole derivatives possible below 1%
Stabilizers/Additives: None typically added
Inhalation: Remove from exposure area, seek fresh air, medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water, consult physician if irritation occurs
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, seek medical advice if irritation continues
Ingestion: Rinse mouth, never give anything by mouth to an unconscious person, seek medical guidance if large quantities are swallowed
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, or water spray
Unsuitable Media: High-pressure water streams may disperse powder
Specific Hazards from Combustion: Emits carbon monoxide, carbon dioxide, nitrogen oxides on decomposition
Special Protective Equipment: Firefighters wear self-contained breathing apparatus (SCBA) and protective clothing
Advice to Firefighters: Operate from upwind, avoid inhalation of smoke and gases, contain fire-fighting water to prevent local contamination
Personal Precautions: Wear gloves, eye protection, and dust mask
Environmental Precautions: Prevent entry into drains, sewers, surface water or soil
Cleanup Methods: Gently scoop or sweep up without generating dust, place in suitable labeled container for disposal, ventilate area well
Decontamination: Wash contaminated surfaces with soap and water, avoid creating slurry that could enter drains
Handling: Use only in well-ventilated areas, avoid breathing dust, prevent contact with eyes and skin by wearing personal protective equipment, keep away from food and beverages
Storage: Store in tightly sealed original containers, in a cool, dry, well-ventilated area, away from incompatible substances such as strong acids, oxidizers, direct heat and sunlight, store at room temperature but avoid freezing or excessive heat
Permissible Exposure Limits: No specific occupational exposure limits assigned
Engineering Controls: Work in ventilated enclosure or fume hood, utilize local exhaust, monitor airborne concentrations in workspace
Personal Protective Equipment (PPE): Safety glasses or goggles, chemical-resistant gloves, laboratory coat, dust mask or respirator in case of excessive dust generation
Hygiene Measures: Wash hands thoroughly after handling, do not eat, drink, or smoke while working, remove contaminated clothing
Appearance: White to off-white crystalline powder
Odor: Odorless or very slight benzimidazole-like
pH: Slightly basic in solution
Melting Point: 115–118°C
Boiling Point: Not readily determined, decomposes before boiling
Vapor Pressure: Not significant at ambient conditions
Solubility: Slightly soluble in water, freely soluble in ethanol or chloroform
Density: About 1.1 g/cm³
Partition coefficient (log P): Estimated 1.7–2.2
Other Data: No explosive or oxidizing properties noted
Chemical Stability: Stable under standard conditions, retains structure at room temperature
Reactivity: Not reactive under normal laboratory handling
Incompatible Materials: Strong acids, strong oxidizing agents
Conditions to Avoid: Moisture, strong heat sources, direct sunlight, open containers
Hazardous Decomposition Products: Combustion produces toxic nitrogen oxides, benzene derivatives
Acute Toxicity: Low oral toxicity in animal studies, estimated LD50 (oral, rat) above 500 mg/kg
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms of Overexposure: Nausea, vomiting, headache, mild skin and eye irritation, drowsiness in large doses
Sensitization: Not considered a skin sensitizer
Carcinogenicity: Not listed by IARC, NTP, or OSHA as carcinogen
Mutagenicity: No known mutagenic activity under normal usage
Repeated Dose Toxicity: No data indicating long-term organ damage in mammals at therapeutic doses
Ecotoxicity: Low toxicity reported for aquatic organisms, limited data available
Persistence and Degradability: Potential for slow degradation in water and soil
Bioaccumulation: Not expected to bioaccumulate significantly, moderate log P value
Mobility in Soil: Moderate mobility, may leach with water flow if spilled in large quantities
Other Adverse Effects: Use caution to minimize discharge into the environment, as chronic effects are not fully assessed
Disposal Methods: Collect waste for incineration or disposal in authorized chemical landfill under local, state, and federal regulations
Empty Container Precautions: Triple rinse containers, dispose as hazardous waste
Special Instructions: Do not discharge into drains, waterways, or uncontrolled environments
UN Number: Not assigned for Dibazol
UN Proper Shipping Name: Not regulated as dangerous goods
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Environmental Hazards: No Marine Pollutant assigned
Transport Precautions: Protect from physical damage and moisture, keep containers tightly sealed during transit
TSCA Status: Not listed for commercial purposes as bulk chemical in the US
REACH Status: Registration might apply for quantities above 1 ton/year in EU
SARA Title III: Not classified under hazardous substances
California Proposition 65: Not listed
Labelling Requirements: Pharmaceutical standards apply, label with product and hazard details, handle following GMP and institutional guidelines
Other Regulations: Federal, state, and local regulations may apply; users encouraged to verify compliance status before importing or manufacturing in new regions